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  1. Article ; Online: Randomly Layered Superstructure of In

    Jiang, Shaojie / Chen, Xiaobo / Huang, Xin / Li, Can / Wang, Zhongwu / Zhao, Bo / Zhang, Lihua / Zhou, Guangwen / Fang, Jiye

    Journal of the American Chemical Society

    2024  Volume 146, Issue 12, Page(s) 8598–8606

    Abstract: This study outlines the preparation and characterization of a unique superlattice composed of indium oxide ( ... ...

    Abstract This study outlines the preparation and characterization of a unique superlattice composed of indium oxide (In
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.4c00563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reconfigurable Tri-Mode Metasurface for Broadband Low Observation, Wide-Range Tracing, and Backscatter Communication.

    Ning, Jing / Zheng, Yilin / Wang, Shaojie / Jiang, Tian / Zhao, Junming / Chen, Ke / Feng, Yijun

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2024  Volume 11, Issue 15, Page(s) e2304879

    Abstract: In the current prevalent complex electromagnetic (EM) environment, intelligent methods for versatile and integrated control of EM waves using compact devices are both essential and challenging. These varied wave control objectives can at times conflict ... ...

    Abstract In the current prevalent complex electromagnetic (EM) environment, intelligent methods for versatile and integrated control of EM waves using compact devices are both essential and challenging. These varied wave control objectives can at times conflict with one another, such as the need for broad absorption to remain inconspicuous, while also requiring enhanced backward scattering for highly reliable tracing and secure communication. To address these sophisticated challenges, a microwave-frequency reconfigurable tri-mode metasurface (RTMM) is introduced. The proposed innovation enables three distinct operational modes: broadband low observation, enhanced EM wave tracing, and backscatter communication over a wide-angle range by simple control of the PIN diodes embedded in each meta-atom. The proof-of-concept demonstration of the fabricated prototype verified the switchable tri-mode performance of the RTMM. This proposed RTMM can be adapted to various applications, including EM shielding, target detection, and secure communication in complex and threatening EM environments, paving the way for environmentally-adaptive EM wave manipulation.
    Language English
    Publishing date 2024-02-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202304879
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  3. Book ; Online: Contour Context

    Jiang, Binqian / Shen, Shaojie

    Abstract Structural Distribution for 3D LiDAR Loop Detection and Metric Pose Estimation

    2023  

    Abstract: This paper proposes \textit{Contour Context}, a simple, effective, and efficient topological loop closure detection pipeline with accurate 3-DoF metric pose estimation, targeting the urban utonomous driving scenario. We interpret the Cartesian birds' eye ...

    Abstract This paper proposes \textit{Contour Context}, a simple, effective, and efficient topological loop closure detection pipeline with accurate 3-DoF metric pose estimation, targeting the urban utonomous driving scenario. We interpret the Cartesian birds' eye view (BEV) image projected from 3D LiDAR points as layered distribution of structures. To recover elevation information from BEVs, we slice them at different heights, and connected pixels at each level will form contours. Each contour is parameterized by abstract information, e.g., pixel count, center position, covariance, and mean height. The similarity of two BEVs is calculated in sequential discrete and continuous steps. The first step considers the geometric consensus of graph-like constellations formed by contours in particular localities. The second step models the majority of contours as a 2.5D Gaussian mixture model, which is used to calculate correlation and optimize relative transform in continuous space. A retrieval key is designed to accelerate the search of a database indexed by layered KD-trees. We validate the efficacy of our method by comparing it with recent works on public datasets.

    Comment: 7 pages, 7 figures, accepted by ICRA 2023
    Keywords Computer Science - Robotics ; Computer Science - Computer Vision and Pattern Recognition
    Subject code 006
    Publishing date 2023-02-13
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Editorial: Aging-friendly environments and healthy aging.

    Jiang, Yuling / Wu, Yifei / Li, Shaojie / Fu, Shihui / Lv, Yuebin / Lin, Hualiang / Yao, Yao

    Frontiers in medicine

    2023  Volume 10, Page(s) 1211632

    Language English
    Publishing date 2023-06-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1211632
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  5. Article: Long-segment common carotid occlusion presenting with limb-shaking transient ischemic attack: Case report.

    Jiang, Qingjun / Bai, Jun / Nie, Shaojie / Jin, Jie / Qu, Lefeng

    Frontiers in surgery

    2023  Volume 9, Page(s) 1028004

    Abstract: Background: Limb-shaking transient ischemic attack (LS-TIA) is a rare manifestation of carotid artery occlusion. Common carotid artery occlusion (CCAO) is a relatively rare condition, and both its natural history and recommendations for treatment are ... ...

    Abstract Background: Limb-shaking transient ischemic attack (LS-TIA) is a rare manifestation of carotid artery occlusion. Common carotid artery occlusion (CCAO) is a relatively rare condition, and both its natural history and recommendations for treatment are still unclear.
    Case description: A 67-year-old female suffered from transient episodes of unilateral limb shaking. Computer tomographic angiography (CTA) showed long-segment occlusion of the right common carotid artery. Computer tomographic perfusion (CTP) demonstrated hypoperfusion of the corpus striatum, which suggests that hemodynamic failure is a potential mechanism underlying the LS-TIA secondary to common carotid artery occlusion. The occlusion was successfully recanalized by retrograde common carotid endarterectomy, and the episodes of left limb shaking disappeared after surgery.
    Conclusions: The occlusion was successfully recanalized by retrograde common carotid endarterectomy, and the episodes of left limb shaking disappeared after surgery. Hypoperfusion of the corpus striatum might be a potential mechanism underlying the LS-TIA secondary to common carotid occlusion.
    Language English
    Publishing date 2023-02-15
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2022.1028004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Analysis of Dietary Patterns Associated with Kidney Stone Disease Based on Data-Driven Approaches: A Case-Control Study in Shanghai.

    Wang, Yifei / Liu, Shaojie / Zhao, Qi / Wang, Na / Liu, Xing / Zhang, Tiejun / He, Gengsheng / Zhao, Genming / Jiang, Yonggen / Chen, Bo

    Nutrients

    2024  Volume 16, Issue 2

    Abstract: The main objective of this study was to analyze dietary patterns using data-driven approaches and to explore preventive or risk dietary factors for kidney stone disease (KSD). A case-control matching study was conducted in adults ( ...

    Abstract The main objective of this study was to analyze dietary patterns using data-driven approaches and to explore preventive or risk dietary factors for kidney stone disease (KSD). A case-control matching study was conducted in adults (
    MeSH term(s) Adult ; Female ; Male ; Humans ; Case-Control Studies ; Dietary Patterns ; China/epidemiology ; Kidney Calculi/epidemiology ; Kidney Calculi/etiology ; Kidney Calculi/prevention & control ; Meat
    Language English
    Publishing date 2024-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16020214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021.

    Wu, Qing / Qian, Wei / Sun, Xiaoli / Jiang, Shaojie

    Journal of hematology & oncology

    2022  Volume 15, Issue 1, Page(s) 143

    Abstract: The United States Food and Drug Administration (US FDA) has always been a forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs (excluding vaccines, cell-based therapies, and gene therapy products) have been approved as new ... ...

    Abstract The United States Food and Drug Administration (US FDA) has always been a forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs (excluding vaccines, cell-based therapies, and gene therapy products) have been approved as new molecular entities (NMEs) or biologics license applications (BLAs). A total of 228 of these 1050 drugs were identified as cancer therapeutics or cancer-related drugs, and 120 of them were classified as therapeutic drugs for solid tumors according to their initial indications. These drugs have evolved from small molecules with broad-spectrum antitumor properties in the early stage to monoclonal antibodies (mAbs) and antibody‒drug conjugates (ADCs) with a more precise targeting effect during the most recent decade. These drugs have extended indications for other malignancies, constituting a cancer treatment system for monotherapy or combined therapy. However, the available targets are still mainly limited to receptor tyrosine kinases (RTKs), restricting the development of antitumor drugs. In this review, these 120 drugs are summarized and classified according to the initial indications, characteristics, or functions. Additionally, RTK-targeted therapies and immune checkpoint-based immunotherapies are also discussed. Our analysis of existing challenges and potential opportunities in drug development may advance solid tumor treatment in the future.
    MeSH term(s) Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Biological Products/therapeutic use ; Humans ; Immune Checkpoint Inhibitors ; Immunoconjugates/therapeutic use ; Neoplasms/drug therapy ; Pharmaceutical Preparations ; Tyrosine ; United States ; United States Food and Drug Administration
    Chemical Substances Antibodies, Monoclonal ; Antineoplastic Agents ; Biological Products ; Immune Checkpoint Inhibitors ; Immunoconjugates ; Pharmaceutical Preparations ; Tyrosine (42HK56048U)
    Language English
    Publishing date 2022-10-08
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429631-4
    ISSN 1756-8722 ; 1756-8722
    ISSN (online) 1756-8722
    ISSN 1756-8722
    DOI 10.1186/s13045-022-01362-9
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  8. Article ; Online: Editorial

    Yuling Jiang / Yifei Wu / Shaojie Li / Shihui Fu / Yuebin Lv / Hualiang Lin / Yao Yao

    Frontiers in Medicine, Vol

    Aging-friendly environments and healthy aging

    2023  Volume 10

    Keywords aging-friendly environment ; healthy aging ; physical environment ; social environment ; health policy ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: A Quantitative Detection Algorithm for Multi-Test Line Lateral Flow Immunoassay Applied in Smartphones.

    Zhang, Shenglan / Jiang, Xincheng / Lu, Siqi / Yang, Guangtian / Wu, Shaojie / Chen, Liqiang / Pan, Hongcheng

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 14

    Abstract: The traditional lateral flow immunoassay (LFIA) detection method suffers from issues such as unstable detection results and low quantitative accuracy. In this study, we propose a novel multi-test line lateral flow immunoassay quantitative detection ... ...

    Abstract The traditional lateral flow immunoassay (LFIA) detection method suffers from issues such as unstable detection results and low quantitative accuracy. In this study, we propose a novel multi-test line lateral flow immunoassay quantitative detection method using smartphone-based SAA immunoassay strips. Following the utilization of image processing techniques to extract and analyze the pigments on the immunoassay strips, quantitative analysis of the detection results was conducted. Experimental setups with controlled lighting conditions in a dark box were designed to capture samples using smartphones with different specifications for analysis. The algorithm's sensitivity and robustness were validated by introducing noise to the samples, and the detection performance on immunoassay strips using different algorithms was determined. The experimental results demonstrate that the proposed lateral flow immunoassay quantitative detection method based on image processing techniques achieves an accuracy rate of 94.23% on 260 samples, which is comparable to the traditional methods but with higher stability and lower algorithm complexity.
    MeSH term(s) Smartphone ; Algorithms ; Immunoassay/methods ; Image Processing, Computer-Assisted ; Limit of Detection
    Language English
    Publishing date 2023-07-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23146401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Discovery and Characterization of Moracin C as an Anti-Gouty Arthritis/Hyperuricemia Candidate by Docking-Based Virtual Screening and Pharmacological Evaluation.

    Lv, Minyi / Jiang, Shaoyan / Deng, Shaojie / Zhao, Zean / Yang, Zichao / Liu, Lu / Ke, Tao

    Journal of natural products

    2023  Volume 86, Issue 9, Page(s) 2091–2101

    Abstract: In the present study, a natural product database of compounds associated with herbs traditionally verified to treat gout/hyperuricemia/arthritis was constructed. 3D-shape and docking-based virtual screening was conducted. To identify potential xanthine ... ...

    Abstract In the present study, a natural product database of compounds associated with herbs traditionally verified to treat gout/hyperuricemia/arthritis was constructed. 3D-shape and docking-based virtual screening was conducted. To identify potential xanthine oxidase (XOD) inhibitors in the database, eight compounds with commercial availability were identified as high 3D-shape similarity with febuxostat (
    MeSH term(s) Mice ; Rats ; Animals ; Hyperuricemia/drug therapy ; Hyperuricemia/metabolism ; Tumor Necrosis Factor-alpha ; Rats, Sprague-Dawley ; Arthritis, Gouty/drug therapy ; Arthritis, Gouty/chemically induced ; Arthritis, Gouty/metabolism ; Uric Acid/adverse effects ; Enzyme Inhibitors
    Chemical Substances moracin C ; Tumor Necrosis Factor-alpha ; isoformononetin ; Uric Acid (268B43MJ25) ; Enzyme Inhibitors
    Language English
    Publishing date 2023-08-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.3c00099
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