Result 1 - 10 of total 10
Western journal of medicine and surgery
2024 Volume 4, Issue 10, Page(s) 304–310
| Language | English |
|---|---|
| Publishing date | 2024-01-11 |
| Publishing country | United States |
| Document type | Journal Article |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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Medico-chirurgical transactions
2010 Volume 38, Page(s) 51–58
| Language | English |
|---|---|
| Publishing date | 2010-10-04 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 760946-2 |
| ISSN | 0959-5287 |
| ISSN | 0959-5287 |
| DOI | 10.1177/095952875503800103 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 7110: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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Journal of immunology (Baltimore, Md. : 1950)
1996 Volume 156, Issue 6, Page(s) 2324–2330
Abstract: We have investigated the effect of exogenous IL-7 on replication of HIV-1 in PBMCs isolated from asymptomatic, chronically infected donors. We show that IL-7 induced virus replication and increased proviral DNA levels in CD8- PBMC cultures. IL-7 also ... ...
| Abstract | We have investigated the effect of exogenous IL-7 on replication of HIV-1 in PBMCs isolated from asymptomatic, chronically infected donors. We show that IL-7 induced virus replication and increased proviral DNA levels in CD8- PBMC cultures. IL-7 also increased the levels of doubly spliced HIV-1 tat RNA in these cultures. In comparison, IL-2 induced lower levels of virus production than IL-7, but had a more pronounced effect on cell proliferation. The IL-7-mediated increase in virus replication was not inhibited by neutralizing mAbs to IL-1 beta, IL-2, IL-6, or TNF-alpha, and was only partially dependent on ligation of the T cell accessory molecule CD28. CD8+ cells inhibited the increase in viral replication following IL-7 stimulation, but did not prevent virus replication following ligation of CD3 in the presence of IL-7. The data shows that IL-7 regulates HIV-1 replication in naturally infected PBMCs. |
|---|---|
| MeSH term(s) | Antiviral Agents/immunology ; CD28 Antigens/metabolism ; CD28 Antigens/physiology ; CD8-Positive T-Lymphocytes/immunology ; Cells, Cultured ; Cytokines/antagonists & inhibitors ; Genes, tat/drug effects ; HIV Infections/immunology ; HIV Infections/virology ; HIV-1/drug effects ; HIV-1/immunology ; HIV-1/physiology ; Humans ; Interleukin-7/pharmacology ; Leukocytes, Mononuclear/immunology ; Leukocytes, Mononuclear/virology ; RNA, Messenger/biosynthesis ; Virus Replication/drug effects ; Virus Replication/immunology |
| Chemical Substances | Antiviral Agents ; CD28 Antigens ; Cytokines ; Interleukin-7 ; RNA, Messenger |
| Language | English |
| Publishing date | 1996-03-15 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 3056-9 |
| ISSN | 1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381 |
| ISSN (online) | 1550-6606 |
| ISSN | 0022-1767 ; 1048-3233 ; 1047-7381 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ud II Zs.37: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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| Zs.MG 28: Show issues |
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1986 Volume 366, Issue 1-2, Page(s) 98–105
Abstract: ... pharmacologically characterized previously and divided into two classes: class A agonists (e.g. acetylcholine ... class B agonists (e.g. bethanecol and oxotremorine-1) which poorly stimulate PI turnover and do not ...
| Abstract | The increases in firing rates of hippocampal cells were examined following microiontophoretic application of several muscarinic cholinergic receptor agonists. The agonists studied had been pharmacologically characterized previously and divided into two classes: class A agonists (e.g. acetylcholine, carbamylcholine, and oxotremorine-M) which maximally stimulate PI turnover and reveal mAChR heterogeneity, and class B agonists (e.g. bethanecol and oxotremorine-1) which poorly stimulate PI turnover and do not alter mAChR conformation/orientation in the hippocampus. While comparable stimulatory effects on hippocampal pyramidal cell firing rates were seen with both classes of agonists during short (20 s) ejection periods, longer applications (greater than 25 s) produced class-dependent differential firing patterns. Prolonged ejection of class A agonists selectively desensitized cells to further, continued application in the same ejection period, and the firing rates declined. Class B agonists produced stimulatory responses in hippocampal cells during the entire ejection period, and DE was not observed. This desensitization effect (DE) was observed only for bursts and not for simple spikes. |
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| MeSH term(s) | Acetylcholine/pharmacology ; Animals ; Benzodiazepinones/pharmacology ; Bethanechol ; Bethanechol Compounds/pharmacology ; Carbachol/pharmacology ; Hippocampus/drug effects ; Hippocampus/physiology ; Male ; Molecular Conformation ; Oxotremorine/pharmacology ; Pirenzepine ; Rats ; Rats, Inbred Strains ; Receptors, Muscarinic/drug effects ; Receptors, Muscarinic/physiology |
| Chemical Substances | Benzodiazepinones ; Bethanechol Compounds ; Receptors, Muscarinic ; Bethanechol (004F72P8F4) ; Pirenzepine (3G0285N20N) ; Oxotremorine (5RY0UWH1JL) ; Carbachol (8Y164V895Y) ; Acetylcholine (N9YNS0M02X) |
| Language | English |
| Publishing date | 1986-02-26 |
| Publishing country | Netherlands |
| Document type | Comparative Study ; Journal Article |
| ZDB-ID | 1200-2 |
| ISSN | 1872-6240 ; 0006-8993 |
| ISSN (online) | 1872-6240 |
| ISSN | 0006-8993 |
| DOI | 10.1016/0006-8993(86)91284-9 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 161: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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1876 Volume 1, Issue 793, Page(s) 313–314
| Language | English |
|---|---|
| Publishing date | 1876-03-11 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 80088-0 |
| ISSN | 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146 |
| ISSN | 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146 |
| DOI | 10.1136/bmj.1.793.313 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ua VI Zs.10: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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1876 Volume 1, Issue 792, Page(s) 279–280
| Language | English |
|---|---|
| Publishing date | 1876-03-04 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 80088-0 |
| ISSN | 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146 |
| ISSN | 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146 |
| DOI | 10.1136/bmj.1.792.279 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ua VI Zs.10: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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1868
| Author's details | by George Critchett |
|---|---|
| MeSH term(s) | Education, Medical |
| Language | English |
| Size | 19 p. |
| Publisher | Chiswick Press |
| Publishing place | London |
| Document type | Book |
| Database | Catalogue of the US National Library of Medicine (NLM) |
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at the commencement of the session, 1859-60
1859
| Language | English |
|---|---|
| Size | 16 p. |
| Publishing place | London |
| Document type | Book |
| Note | Author's autograph presentation copy. |
| Database | Catalogue of the US National Library of Medicine (NLM) |
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with some novel suggestions respecting the operation
1855
| Author's details | by G. Critchett |
|---|---|
| MeSH term(s) | Strabismus/surgery |
| Language | English |
| Size | 12 p. :, ill. ;, 19 cm. |
| Publisher | Printed by J. Anderson |
| Publishing place | Deptford |
| Document type | Book |
| Note | Cover title. ; In manuscript on cover: With the authors compts. |
| Database | Catalogue of the US National Library of Medicine (NLM) |
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Delivered at the London Hospital, during the summer of 1848
1849
| Language | English |
|---|---|
| Size | vii, 121 p. |
| Publisher | Churchill |
| Publishing place | London |
| Document type | Book |
| Database | Catalogue of the US National Library of Medicine (NLM) |
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