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  1. Article ; Online: Cabada, Ladislav – Jurek, Petr a kol.

    Vít Beneš

    Central European Political Studies Review, Vol 13, Iss 2-3, Pp 264-

    Mentální mapy, teritorialita a identita v evropském prostředí. Plzeň: Aleš Čeněk, 2010

    2011  Volume 269

    Abstract: ... book ... ...

    Abstract book review
    Keywords Political science (General) ; JA1-92 ; Political science ; J ; DOAJ:Political Science ; DOAJ:Law and Political Science ; Political theory ; JC11-607
    Language Czech
    Publishing date 2011-09-01T00:00:00Z
    Publisher Masaryk University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Caspase-9 Is a Positive Regulator of Osteoblastic Cell Migration Identified by diaPASEF Proteomics.

    Říhová, Kamila / Lapčík, Petr / Veselá, Barbora / Knopfová, Lucia / Potěšil, David / Pokludová, Jana / Šmarda, Jan / Matalová, Eva / Bouchal, Pavel / Beneš, Petr

    Journal of proteome research

    2024  

    Abstract: Caspase-9 is traditionally considered the initiator caspase of the intrinsic apoptotic pathway. In the past decade, however, other functions beyond initiation/execution of cell death have been described including cell type-dependent regulation of ... ...

    Abstract Caspase-9 is traditionally considered the initiator caspase of the intrinsic apoptotic pathway. In the past decade, however, other functions beyond initiation/execution of cell death have been described including cell type-dependent regulation of proliferation, differentiation/maturation, mitochondrial, and endosomal/lysosomal homeostasis. As previous studies revealed nonapoptotic functions of caspases in osteogenesis and bone homeostasis, this study was performed to identify proteins and pathways deregulated by knockout of caspase-9 in mouse MC3T3-E1 osteoblasts. Data-independent acquisition-parallel accumulation serial fragmentation (diaPASEF) proteomics was used to compare protein profiles of control and caspase-9 knockout cells. A total of 7669 protein groups were quantified, and 283 upregulated/141 downregulated protein groups were associated with the caspase-9 knockout phenotype. The deregulated proteins were mainly enriched for those associated with cell migration and motility and DNA replication/repair. Altered migration was confirmed in MC3T3-E1 cells with the genetic and pharmacological inhibition of caspase-9. ABHD2, an established regulator of cell migration, was identified as a possible substrate of caspase-9. We conclude that caspase-9 acts as a modulator of osteoblastic MC3T3-E1 cell migration and, therefore, may be involved in bone remodeling and fracture repair.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2078618-9
    ISSN 1535-3907 ; 1535-3893
    ISSN (online) 1535-3907
    ISSN 1535-3893
    DOI 10.1021/acs.jproteome.3c00641
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  3. Article ; Online: Aneurysmal 99m Tc-HMPAO Uptake in Brain Death.

    Do, Danka / Suhaj, Petr / Benes, Jiri / Matej, Radoslav / Lang, Otto

    Clinical nuclear medicine

    2024  Volume 49, Issue 4, Page(s) 348–350

    Abstract: Abstract: A 41-year-old man was admitted to hospital due to sudden loss of consciousness. A regional brain perfusion SPECT/low-dose CT showed abnormal 99m Tc-HMPAO uptake in the right hemisphere frontotemporally without any other supratentorial or ... ...

    Abstract Abstract: A 41-year-old man was admitted to hospital due to sudden loss of consciousness. A regional brain perfusion SPECT/low-dose CT showed abnormal 99m Tc-HMPAO uptake in the right hemisphere frontotemporally without any other supratentorial or infratentorial radiotracer uptake. A neuropathological examination disclosed a middle cerebral artery aneurysm. Presumably, vessel wall fibrosis prevented collapse. Multiple transmural dissections of the fibrotic aneurysmal wall were the source of the subarachnoid hemorrhage. This interesting image shows that radiotracer accumulation in cerebral artery aneurysms can be a diagnostic pitfall in brain death scintigraphy assessment.
    MeSH term(s) Male ; Humans ; Adult ; Brain Death/diagnostic imaging ; Brain/diagnostic imaging ; Biological Transport ; Neuroimaging ; Single Photon Emission Computed Tomography Computed Tomography
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000005103
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  4. Article: The Effect of Heterophoria on the Size of Distance and Near Fusion Vergence.

    Veselý, Petr / Beneš, Pavel / Sokolová, Jana Šidlová / Záděrová, Petra / Došková, Hana

    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti

    2024  Volume 80, Issue 1, Page(s) 18–23

    Abstract: Aims: To demonstrate changes in distance and near fusional vergence measured with prism bars, while compensating for present heterophoria using current ametropia correction. In addition, to determine the differences in values of the AC/A ratio ... ...

    Title translation Vliv heteroforie na velikost fúzních rezerv do dálky a do blízka.
    Abstract Aims: To demonstrate changes in distance and near fusional vergence measured with prism bars, while compensating for present heterophoria using current ametropia correction. In addition, to determine the differences in values of the AC/A ratio determined by the heterophoric (calculation) and gradient methods.
    Material and methods: The basic sample includes 19 subjects with a mean age of 21.5 ±3.0 years (min. 18, max. 27). We used the Von Graefe technique for examination of distance and near phoria, and prism bars for examination of fusion vergences measured in prism diopters. We divided the basic cohort into six research sets according to the size of distance and near heterophoria. This was a cohort of patients with distance (D OR) and near orthophoria (N OR), a cohort of patients with distance (D EX) and near exophoria (N EX) and a set of patients with distance (D ES) and near esophoria (N ES).
    Results: In the case of both groups with exophoria (distance, near) we found a statistically significant result only for negative fusion vergence (NFV). There was a statistically significant increase in NFV in the sample with distance and near exophoria (D EX, p = 0.01 and B EX, p = 0.02, respectively). In our study, we also demonstrated a statistically significant difference (p < 0.001) in the values of the AC/A ratio measured by the gradient and heterophoric methods. The values determined by the gradient method are lower (3.0 ±1.1 pD/D versus 5.8 ±0.9 pD/D) than by the heterophoric method.
    Conclusion: By comparing fusion vergence values in patients with exophoria and orthophoria, we demonstrated that in the presence of distance or near exophoria there is an increase in ipsilateral fusion vergence. In the case of an increase in ipsilateral fusion vergence, the finding was statistically significant both distance and near (p = 0.01 and p = 0.02, respectively). By contrast, we were unable to prove this fact in the group of patients with esophoria. In our study, we also demonstrated a statistically significant difference (p < 0.001) in the values of the AC/A ratio measured by the gradient and heterophoric methods. The values determined by the gradient method are lower (3.0 ±1.1 pD/D versus 5.8 ±0.9 pD/D) than by the heterophoric method.
    MeSH term(s) Humans ; Adolescent ; Young Adult ; Adult ; Esotropia/diagnosis ; Exotropia/diagnosis ; Vision, Binocular ; Convergence, Ocular ; Strabismus
    Language English
    Publishing date 2024-02-16
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 1235298-6
    ISSN 1805-4447 ; 1211-9059 ; 0009-059X
    ISSN (online) 1805-4447
    ISSN 1211-9059 ; 0009-059X
    DOI 10.31348/2024/5
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  5. Article ; Online: Functionalization of ZnAl-Layered Double Hydroxide with Ensulizole and Its Application as a UV-Protective Agent in a Transparent Polymer Coating.

    Melánová, Klára / Kopecká, Kateřina / Beneš, Ludvík / Kutálek, Petr / Knotek, Petr / Zmrhalová, Zuzana / Svoboda, Jan

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 17

    Abstract: In this study, we propose a promising photoprotective additive that combines the advantages of both organic UV absorbers and inorganic particles without compromising the properties of the paint material. This additive involves the intercalation of a well- ...

    Abstract In this study, we propose a promising photoprotective additive that combines the advantages of both organic UV absorbers and inorganic particles without compromising the properties of the paint material. This additive involves the intercalation of a well-known organic UV absorber, 2-phenylbenzimidazole-5-sulfonic acid (PBISA), into zinc-aluminum layered double hydroxide (ZnAl-LDH). Three ZnAl-LDH intercalates with PBISA were prepared using various methods based on either anion exchange or direct synthesis. The intercalates were characterized using powder X-ray diffraction, thermogravimetry, elemental analysis, and IR and UV-Vis spectroscopies. The composition and basal spacings of all three intercalates are very similar. An effective UV protection film was prepared when the ZnAl-PBISA-1 intercalate was incorporated into polyurethane-acrylate lacquer. The resultant UV protective film exhibited stability and uniform distribution of the intercalated fillers. Some minimal particle sedimentation and aggregation were observed on the cured film's underside, but did not compromise the films' UV protective properties. The prepared lacquers with intercalated fillers offer a viable solution for the surface modification of plastic products.
    Language English
    Publishing date 2023-08-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28176262
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  6. Article: Domácí parenterální výživa v onkologii.

    Beneš, Petr

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

    2015  Volume 28, Issue 1, Page(s) 61–62

    Title translation Home parenteral nutrition in oncology.
    MeSH term(s) Czech Republic ; Humans ; Neoplasms/therapy ; Parenteral Nutrition, Home/methods
    Language Czech
    Publishing date 2015
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 1217739-8
    ISSN 0862-495X
    ISSN 0862-495X
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    Zs.A 4181: Show issues Location:
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  7. Article ; Online: Partial medial clinoidectomy with optic canal roof drilling for clipping of ophthalmic artery aneurysms: how I do it.

    Bubeníková, Adéla / Skalický, Petr / Beneš, Vladimír

    Acta neurochirurgica

    2022  Volume 164, Issue 11, Page(s) 2893–2898

    Abstract: Background: Clipping of ophthalmic artery (OA) aneurysms present one of the treatment strategies for long-term disease management. Existing surgical techniques primarily require extra/intradural removal of the anterior clinoid process, carrying a higher ...

    Abstract Background: Clipping of ophthalmic artery (OA) aneurysms present one of the treatment strategies for long-term disease management. Existing surgical techniques primarily require extra/intradural removal of the anterior clinoid process, carrying a higher risk of infection, damage to surrounding structures or technical complications.
    Methods: We present the technique of minimally invasive partial medial clinoidectomy with the unroofing of the optic canal for surgical clipping of OA aneurysms, and besides its pros and cons, we also discuss proper technical indications.
    Conclusion: The partial medial clinoidectomy improves manoeuvrability around the paraclinoid region, provides better protection for adjacent structures and renders excellent treatment outcome.
    MeSH term(s) Humans ; Ophthalmic Artery/diagnostic imaging ; Ophthalmic Artery/surgery ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/surgery ; Carotid Artery, Internal/surgery ; Neurosurgical Procedures/methods ; Sphenoid Bone/surgery
    Language English
    Publishing date 2022-09-15
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-022-05352-1
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  8. Article: Application of Raney Al-Ni Alloy for Simple Hydrodehalogenation of Diclofenac and Other Halogenated Biocidal Contaminants in Alkaline Aqueous Solution under Ambient Conditions.

    Bendová, Helena / Kamenická, Barbora / Weidlich, Tomáš / Beneš, Ludvík / Vlček, Milan / Lacina, Petr / Švec, Petr

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 11

    Abstract: Raney Al-Ni contains 62% of ... ...

    Abstract Raney Al-Ni contains 62% of Ni
    Language English
    Publishing date 2022-05-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15113939
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  9. Article ; Online: The Czech Home Parenteral Nutrition Registry REDNUP: Comprehensive Analysis of Adult Patients' Data.

    Koudelková, Kateřina / Waldauf, Petr / Wohl, Petr / Šenkyřík, Michal / Beneš, Petr / Kohout, Pavel / Vejmelka, Jiří / Maňák, Jan / Těšínský, Pavel / Novák, František / Meisnerová, Eva / Fencl, Filip / Gojda, Jan

    Annals of nutrition & metabolism

    2024  

    Abstract: Introduction: Home parenteral nutrition (HPN) is the primary treatment modality for patients with chronic intestinal failure, one of the least common organ failures. This article provides a retrospective analysis of the data collected on HPN patients in ...

    Abstract Introduction: Home parenteral nutrition (HPN) is the primary treatment modality for patients with chronic intestinal failure, one of the least common organ failures. This article provides a retrospective analysis of the data collected on HPN patients in the Czech Republic over the past 30 years.
    Methods: National registry data was collected using a standardised online form based on the OASIS registry (Oley-A.S.P.E.N. Information System) across all centres providing HPN in the Czech Republic. Data collected prospectively from adult patients in the HPN program was analysed in the following categories: epidemiology, demographics, underlying syndrome, and diagnosis, complications, and teduglutide therapy prevalence.
    Results: The registry identified a total of 1,838 adult patient records, reflecting almost 1.5 million individual catheter days. The prevalence of HPN has risen considerably over the last few decades, currently reaching 5.5 per 100,000 population. The majority of patients have short bowel syndrome and GI obstruction, with cancer being the most prevalent underlying disease. Catheter-related bloodstream infections have been the most prevalent acute complication. However, the incidence in 2022 was only 0.15 per 1,000 catheter days. The study also observed an increase in the prevalence of patients on palliative HPN over the last decade.
    Conclusion: This study presents a thorough analysis of data from the Czech REDNUP registry. It shows an increasing prevalence of HPN, namely in the palliative patient group. The sharing of national data can improve understanding of this rare condition and facilitate the development of international guidelines.
    Language English
    Publishing date 2024-03-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 392341-1
    ISSN 1421-9697 ; 0250-6807 ; 1018-9688
    ISSN (online) 1421-9697
    ISSN 0250-6807 ; 1018-9688
    DOI 10.1159/000538232
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  10. Article ; Online: Corrigendum to "Nuclear factor of activated T-cells 1 increases sensitivity of v-myb transformed monoblasts to all-trans retinoic acid." [Cell Signal 2013:25(7),1546-1555].

    Trčka, Filip / Šmarda, Jan / Knopfová, Lucia / Kuziaková, Kateřina / Beneš, Petr

    Cellular signalling

    2022  Volume 100, Page(s) 110476

    Language English
    Publishing date 2022-09-24
    Publishing country England
    Document type Published Erratum
    ZDB-ID 1002702-6
    ISSN 1873-3913 ; 0898-6568
    ISSN (online) 1873-3913
    ISSN 0898-6568
    DOI 10.1016/j.cellsig.2022.110476
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