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  1. Article: [Rezension von: Randall, Alan, Resource economics]

    Gardner, B. Delworth / Randall, Alan

    American journal of agricultural economics 70 ,2, S. 500-501

    1988  

    Author's details B. Delworth Gardner
    Keywords 40;49
    Language English
    Publisher Oxford University Press
    Publishing place Cary, NC
    Document type Article
    ZDB-ID 218188-5
    ISSN 0002-9092
    ISSN 0002-9092
    Database ECONomics Information System

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  2. Article: Corrigendum: Phylogenomics of the Andean tetraploid clade of the American Amaryllidaceae (subfamily Amaryllidoideae): Unlocking a polyploid generic radiation abetted by continental geodynamics.

    Meerow, Alan W / Gardner, Elliot M / Nakamura, Kyoko

    Frontiers in plant science

    2023  Volume 14, Page(s) 1151864

    Abstract: This corrects the article DOI: 10.3389/fpls.2020.582422.]. ...

    Abstract [This corrects the article DOI: 10.3389/fpls.2020.582422.].
    Language English
    Publishing date 2023-03-02
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1151864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Things We Do for No Reason™: Nil per os for acute pancreatitis.

    Zakko, Alan / Belanger, Matthew J / Gardner, Timothy B

    Journal of hospital medicine

    2023  Volume 18, Issue 10, Page(s) 938–940

    MeSH term(s) Humans ; Pancreatitis/complications ; Pancreatitis/diagnosis ; Pancreatitis/therapy ; Acute Disease ; Enteral Nutrition
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.13047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comparison of clinical and radiological outcomes for the anterior and medial approaches to open reduction in the treatment of bilateral developmental dysplasia of the hip: a systematic review protocol.

    Jenner, Edward Alan / Chauhan, Govind Singh / Burahee, Abdus / Choudri, Junaid / Gardner, Adrian / Bache, Christopher Edward

    Systematic reviews

    2024  Volume 13, Issue 1, Page(s) 72

    Abstract: Background: Developmental dysplasia of the hip (DDH) affects 1-3% of newborns and 20% of cases are bilateral. The optimal surgical management strategy for patients with bilateral DDH who fail bracing, closed reduction or present too late for these ... ...

    Abstract Background: Developmental dysplasia of the hip (DDH) affects 1-3% of newborns and 20% of cases are bilateral. The optimal surgical management strategy for patients with bilateral DDH who fail bracing, closed reduction or present too late for these methods to be used is unclear. There are proponents of both medial approach open reduction (MAOR) and anterior approach open reduction (AOR); however, there is little evidence to inform this debate.
    Methods: We will perform a systematic review designed according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol. We will search the medical and scientific databases including the grey and difficult to locate literature. The Medical Subject Headings "developmental dysplasia of the hip", "congenital dysplasia of the hip", "congenital hip dislocation", "developmental hip dislocation", and their abbreviations, "DDH" and "CDH" will be used, along with the qualifier "bilateral". Reviewers will independently screen records for inclusion and then independently extract data on study design, population characteristics, details of operative intervention and outcomes from the selected records. Data will be synthesised and a meta-analysis performed if possible. If not possible we will analyse data according to Systematic Review without Meta-Analysis guidance. All studies will be assessed for risk of bias. For each outcome measure a summary of findings will be presented in a table with the overall quality of the recommendation assessed using the Grading of Recommendations Assessment Development and Evaluation approach.
    Discussion: The decision to perform MAOR or AOR in patients with bilateral DDH who have failed conservative management is not well informed by the current literature. High-quality, comparative studies are exceptionally challenging to perform for this patient population and likely to be extremely uncommon. A systematic review provides the best opportunity to deliver the highest possible quality of evidence for bilateral DDH surgical management.
    Systematic review registration: The protocol has been registered in the International Prospective Register of Systematic Reviews (PROSPERO ID CRD42022362325).
    MeSH term(s) Humans ; Infant, Newborn ; Infant ; Hip Dislocation ; Developmental Dysplasia of the Hip ; Systematic Reviews as Topic ; Meta-Analysis as Topic ; Hip Dislocation, Congenital/diagnostic imaging ; Hip Dislocation, Congenital/surgery ; Hip Dislocation, Congenital/epidemiology
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2662257-9
    ISSN 2046-4053 ; 2046-4053
    ISSN (online) 2046-4053
    ISSN 2046-4053
    DOI 10.1186/s13643-023-02444-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Indole-3-acetic acid promotes growth in bloom-forming Microcystis via an antioxidant response.

    Baylous, Hunter R / Gladfelter, Matthew F / Gardner, Malia I / Foley, Madalynn / Wilson, Alan E / Steffen, Morgan M

    Harmful algae

    2024  Volume 133, Page(s) 102575

    Abstract: Interactions between bacteria and phytoplankton in the phycosphere facilitate and constrain biogeochemical cycling in aquatic ecosystems. Indole-3-acetic acid (IAA) is a bacterially produced chemical signal that promotes growth of phytoplankton and ... ...

    Abstract Interactions between bacteria and phytoplankton in the phycosphere facilitate and constrain biogeochemical cycling in aquatic ecosystems. Indole-3-acetic acid (IAA) is a bacterially produced chemical signal that promotes growth of phytoplankton and plants. Here, we explored the impact of IAA on bloom-forming cyanobacteria and their associated bacteria. Exposure to IAA and its precursor, tryptophan, resulted in a strong growth response in a bloom of the freshwater cyanobacterium, Microcystis. Metatranscriptome analysis revealed the induction of an antioxidant response in Microcystis upon exposure to IAA, potentially allowing populations to increase photosynthetic rate and overcome internally generated reactive oxygen. Our data reveal that co-occurring bacteria within the phycosphere microbiome exhibit a division of labor for supportive functions, such as nutrient mineralization and transport, vitamin synthesis, and reactive oxygen neutralization. These complex dynamics within the Microcystis phycosphere microbiome are an example of interactions within a microenvironment that can have ecosystem-scale consequences.
    MeSH term(s) Microcystis/physiology ; Antioxidants ; Cyanobacteria ; Phytoplankton ; Microbiota ; Oxygen ; Indoleacetic Acids
    Chemical Substances indoleacetic acid (6U1S09C61L) ; Antioxidants ; Oxygen (S88TT14065) ; Indoleacetic Acids
    Language English
    Publishing date 2024-01-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2091119-1
    ISSN 1878-1470 ; 1568-9883
    ISSN (online) 1878-1470
    ISSN 1568-9883
    DOI 10.1016/j.hal.2024.102575
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: An Electronic Shared Decision-Making App to Improve Asthma Outcomes: A Randomized Controlled Trial.

    Lee, Deborah L / Hammond, John W / Finkel, Kelsey / Gardner, Donna D / Nelson, Belinda / Baptist, Alan P

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 10, Page(s) 3116–3122.e5

    Abstract: Background: Shared decision-making (SDM) incorporates patient values and preferences to optimize asthma management decisions. Available asthma SDM aids primarily focus on medication selection.: Objective: To assess the usability, acceptability, and ... ...

    Abstract Background: Shared decision-making (SDM) incorporates patient values and preferences to optimize asthma management decisions. Available asthma SDM aids primarily focus on medication selection.
    Objective: To assess the usability, acceptability, and preliminary effectiveness of an electronic SDM application, the ACTION (Active Conversation in asthma Treatment shared decisION-making) app, that addressed medication, nonmedication, and COVID-19 concerns for asthma.
    Methods: In this pilot study, 81 participants with asthma were randomized into the control arm or ACTION app intervention. The ACTION app was completed 1 week before a clinic visit, and responses were shared with the medical provider. The primary outcomes were patient satisfaction and SDM quality. Next, ACTION app users (n = 9) and providers (n = 5) provided feedback through separate virtual focus groups. Sessions were coded by comparative analysis.
    Results: The ACTION app group scored higher agreement that providers adequately addressed COVID-19 concerns compared with the control group (4.4 vs 3.7, P = .03). Although the ACTION app group had a higher total 9-item Shared Decision-Making Questionnaire score, this did not reach statistical significance (87.1 vs 83.3, P = .2). However, the ACTION app group demonstrated stronger agreement that their physician knew exactly how they wanted to be involved in decision-making (4.3 vs 3.8, P = .05), providers asked about preferences (4.3 vs 3.8, P = .05), and that different options were thoroughly weighed (4.3 vs 3.8, P = .03). Major focus group themes included that the ACTION app was practical and established a patient-centered agenda.
    Conclusion: An electronic asthma SDM app that incorporates patient preferences regarding nonmedication-related, medication-related, and COVID-19-related concerns is well accepted and can improve patient satisfaction and SDM.
    MeSH term(s) Humans ; Mobile Applications ; Pilot Projects ; COVID-19 ; Asthma/drug therapy ; Decision Making, Shared ; Decision Making
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.06.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Phylogenomics of the Andean Tetraploid Clade of the American Amaryllidaceae (Subfamily Amaryllidoideae): Unlocking a Polyploid Generic Radiation Abetted by Continental Geodynamics.

    Meerow, Alan W / Gardner, Elliot M / Nakamura, Kyoko

    Frontiers in plant science

    2020  Volume 11, Page(s) 582422

    Abstract: One of the two major clades of the endemic American Amaryllidaceae subfam. Amaryllidoideae constitutes the tetraploid-derived ( ...

    Abstract One of the two major clades of the endemic American Amaryllidaceae subfam. Amaryllidoideae constitutes the tetraploid-derived (
    Language English
    Publishing date 2020-11-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2020.582422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Sialic Acid Derivatization of Fluorescently Labeled

    Moran, Alan B / Gardner, Richard A / Wuhrer, Manfred / Lageveen-Kammeijer, Guinevere S M / Spencer, Daniel I R

    Analytical chemistry

    2022  Volume 94, Issue 18, Page(s) 6639–6648

    Abstract: Sialic acids have diverse biological roles, ranging from promoting up to preventing protein and cellular recognition in health and disease. The various functions of these monosaccharides are owed, in part, to linkage variants, and as a result, linkage- ... ...

    Abstract Sialic acids have diverse biological roles, ranging from promoting up to preventing protein and cellular recognition in health and disease. The various functions of these monosaccharides are owed, in part, to linkage variants, and as a result, linkage-specific analysis of sialic acids is an important aspect of glycomic studies. This has been addressed by derivatization strategies using matrix-assisted laser desorption/ionization mass spectrometry (MS) or sialidase digestion arrays followed by liquid chromatography (LC)-MS. Despite this, these approaches are unable to simultaneously provide unambiguous assignment of sialic acid linkages and assess further isomeric glycan features within a single measurement. Thus, for the first time, we present the combination of procainamide fluorescent labeling with sialic acid linkage-specific derivatization via ethyl esterification and amidation for the analysis of released plasma
    MeSH term(s) Chromatography, Reverse-Phase ; N-Acetylneuraminic Acid/chemistry ; Polysaccharides/chemistry ; Sialic Acids/chemistry ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods
    Chemical Substances Polysaccharides ; Sialic Acids ; N-Acetylneuraminic Acid (GZP2782OP0)
    Language English
    Publishing date 2022-04-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.1c02610
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Use of stents in patients undergoing chemotherapy for borderline resectable pancreatic cancer-causing biliary obstruction while awaiting surgery: A cost-effectiveness analysis.

    Almadi, Majid A / Gardner, Timothy B / Chen, Yen-I / Adam, Viviane / Barkun, Jeffrey / Barkun, Alan

    Endoscopy international open

    2021  Volume 9, Issue 9, Page(s) E1413–E1420

    Abstract: Background and study ... ...

    Abstract Background and study aims
    Language English
    Publishing date 2021-08-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-1497-1562
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Findings from a pilot randomized trial of spinal decompression alone or spinal decompression plus instrumented fusion.

    Beresford-Cleary, Nicolas J A / Silman, Alan / Thakar, Chrishan / Gardner, Adrian / Harding, Ian / Cooper, Cushla / Cook, Jonathan / Rothenfluh, Dominique A

    Bone & joint open

    2023  Volume 4, Issue 8, Page(s) 573–579

    Abstract: Aims: Symptomatic spinal stenosis is a very common problem, and decompression surgery has been shown to be superior to nonoperative treatment in selected patient groups. However, performing an instrumented fusion in addition to decompression may avoid ... ...

    Abstract Aims: Symptomatic spinal stenosis is a very common problem, and decompression surgery has been shown to be superior to nonoperative treatment in selected patient groups. However, performing an instrumented fusion in addition to decompression may avoid revision and improve outcomes. The aim of the SpInOuT feasibility study was to establish whether a definitive randomized controlled trial (RCT) that accounted for the spectrum of pathology contributing to spinal stenosis, including pelvic incidence-lumbar lordosis (PI-LL) mismatch and mobile spondylolisthesis, could be conducted.
    Methods: As part of the SpInOuT-F study, a pilot randomized trial was carried out across five NHS hospitals. Patients were randomized to either spinal decompression alone or spinal decompression plus instrumented fusion. Patient-reported outcome measures were collected at baseline and three months. The intended sample size was 60 patients.
    Results: Of the 90 patients screened, 77 passed the initial screening criteria. A total of 27 patients had a PI-LL mismatch and 23 had a dynamic spondylolisthesis. Following secondary inclusion and exclusion criteria, 31 patients were eligible for the study. Six patients were randomized and one underwent surgery during the study period. Given the low number of patients recruited and randomized, it was not possible to assess completion rates, quality of life, imaging, or health economic outcomes as intended.
    Conclusion: This study provides a unique insight into the prevalence of dynamic spondylolisthesis and PI-LL mismatch in patients with symptomatic spinal stenosis, and demonstrates that there is a need for a definitive RCT which stratifies for these groups in order to inform surgical decision-making. Nonetheless a definitive study would need further refinement in design and implementation in order to be feasible.
    Language English
    Publishing date 2023-08-08
    Publishing country England
    Document type Journal Article
    ISSN 2633-1462
    ISSN (online) 2633-1462
    DOI 10.1302/2633-1462.48.BJO-2023-0049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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