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  1. Article ; Online: Caught by NETs.

    Oubihi, Zahra / Wang, Lihui

    Nature reviews. Immunology

    2020  Volume 20, Issue 8, Page(s) 462

    Keywords covid19
    Language English
    Publishing date 2020-06-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-020-0384-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Phytochemical Compounds, Acute Toxicity, Anti-Inflammatory and Antioxidant Activities of

    Oubihi, Asmaa / Ballaoui, Fatima Zahrae / Imtara, Hamada / Jaber, Hassna / Ettouil, Abdessamad / Haida, Sara / Ouhssine, Mohammed / Noman, Omar M / Mothana, Ramzi A / Tarayrah, Mahmoud / Guessous, Zineb

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 3

    Abstract: The present study was conducted to evaluate the acute toxicity and anti-inflammatory effect in vivo, as well as the antioxidant activity, of the essential oil ... ...

    Abstract The present study was conducted to evaluate the acute toxicity and anti-inflammatory effect in vivo, as well as the antioxidant activity, of the essential oil of
    MeSH term(s) Rats ; Mice ; Animals ; Antioxidants/chemistry ; Oils, Volatile/chemistry ; Plant Oils/chemistry ; Anti-Inflammatory Agents/chemistry ; Phytochemicals/pharmacology ; Phytochemicals/therapeutic use ; Plant Extracts/chemistry ; Edema/chemically induced ; Edema/drug therapy
    Chemical Substances Antioxidants ; Oils, Volatile ; Plant Oils ; Anti-Inflammatory Agents ; Phytochemicals ; Plant Extracts
    Language English
    Publishing date 2023-01-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28031355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Phytochemical Compounds, Acute Toxicity, Anti-Inflammatory and Antioxidant Activities of Thymus leptobotrys Murb Essential Oil

    Asmaa Oubihi / Fatima Zahrae Ballaoui / Hamada Imtara / Hassna Jaber / Abdessamad Ettouil / Sara Haida / Mohammed Ouhssine / Omar M. Noman / Ramzi A. Mothana / Mahmoud Tarayrah / Zineb Guessous

    Molecules, Vol 28, Iss 1355, p

    2023  Volume 1355

    Abstract: The present study was conducted to evaluate the acute toxicity and anti-inflammatory effect in vivo, as well as the antioxidant activity, of the essential oil of Thymus leptobotrys Murb . The results indicate that the tested essential oil is non-toxic, ... ...

    Abstract The present study was conducted to evaluate the acute toxicity and anti-inflammatory effect in vivo, as well as the antioxidant activity, of the essential oil of Thymus leptobotrys Murb . The results indicate that the tested essential oil is non-toxic, with an estimated LD50 of 2500 mg kg −1 of mice body weight. The anti-inflammatory test revealed that, at a dose of 200 mg kg −1 , the essential oil reduced rat paw edemas by 89.59% within 3 h of oral administration, this reduction in edema size was greater than that obtained with indomethacin (75.78%). The antioxidant activity (IC50) of Thymus leptobotrys Murb essential oil was 346.896 µg mL −1 and 861.136 mg Trolox equivalent/g essential oil in the 2.2-diphenyl1-picryl-hydrazyl radical scavenging capacity (DPPH) and Trolox equivalent antioxidant capacity (TEAC) assays, respectively. The toxicity test reveals an LD 50 greater than 2500 mg kg −1 of body weight of mice which classifies it within category 5 of non-toxic substances that can be administered orally. These results suggest that the essential oil of Thymus leptobotrys Murb is not toxic, and it represents a valuable source of anti-inflammatory and antioxidant metabolites.
    Keywords Thymus leptobotrys Murb ; essential oil ; acute toxicity ; anti-inflammatory effect ; antioxidant activity ; Organic chemistry ; QD241-441
    Subject code 333
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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