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  1. Article: Efficacy and safety of the herbal formula

    Ha, Na-Yeon / Ko, Seok-Jae / Park, Jae-Woo / Kim, Jinsung

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1157535

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-05-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1157535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Herbal medicine,

    Kim, Keumji / Ko, Seok-Jae / Cho, Soo Ho / Kim, Jinsung / Park, Jae-Woo

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1130257

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-05-19
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1130257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Bio-Inspired Molecularly Imprinted Polymer Electrochemical Sensor for Cortisol Detection Based on O-Phenylenediamine Optimization.

    Kim, Minwoo / Park, Daeil / Park, Joohyung / Park, Jinsung

    Biomimetics (Basel, Switzerland)

    2023  Volume 8, Issue 3

    Abstract: This paper presents a comprehensive investigation of the various parameters involved in the fabrication of a molecularly imprinted polymer (MIP) sensor for the detection of cortisol. Parameters such as monomer concentration, electropolymerization cycles, ...

    Abstract This paper presents a comprehensive investigation of the various parameters involved in the fabrication of a molecularly imprinted polymer (MIP) sensor for the detection of cortisol. Parameters such as monomer concentration, electropolymerization cycles, pH, monomer-template ratio, template removal technique, and rebinding time were optimized to establish a more consistent and effective method for the fabrication of MIP sensors. Under the optimized conditions, the MIP sensor demonstrated a proportional decrease in differential pulse voltammetry peak currents with increasing cortisol concentration in the range of 0.1 to 100 nM. The sensor exhibited excellent sensitivity, with a limit of detection of 0.036 nM. Selectivity experiments using a non-imprinted polymer sensor confirmed the specific binding affinity of the MIP sensor for cortisol, distinguishing it from other steroid hormones. This study provides crucial insights into the development of a reliable and sensitive strategy for cortisol detection using O-PD-based MIPs. These findings laid the foundation for further advancements in MIP research.
    Language English
    Publishing date 2023-07-01
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2313-7673
    ISSN (online) 2313-7673
    DOI 10.3390/biomimetics8030282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The influence of herbal medicine on serum motilin and its effect on human and animal model: a systematic review.

    Cho, Min-Seok / Park, Jae-Woo / Kim, Jinsung / Ko, Seok-Jae

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1286333

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-12-14
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1286333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Highly Sensitive and Wide-Range Detection of Thiabendazole via Surface-Enhanced Raman Scattering Using Bimetallic Nanoparticle-Functionalized Nanopillars.

    Park, Hyunjun / Kim, Gayoung / Kim, Woochang / Park, Eugene / Park, Joohyung / Park, Jinsung

    Biosensors

    2024  Volume 14, Issue 3

    Abstract: Thiabendazole (TBZ) is a benzimidazole; owing to its potent antimicrobial properties, TBZ is extensively employed in agriculture as a fungicide and pesticide. However, TBZ poses environmental risks, and excessive exposure to TBZ through various leakage ... ...

    Abstract Thiabendazole (TBZ) is a benzimidazole; owing to its potent antimicrobial properties, TBZ is extensively employed in agriculture as a fungicide and pesticide. However, TBZ poses environmental risks, and excessive exposure to TBZ through various leakage pathways can cause adverse effects in humans. Therefore, a method must be developed for early and sensitive detection of TBZ over a range of concentrations, considering both human and environmental perspectives. In this study, we used silver nanopillar structures (SNPis) and Au@Ag bimetallic nanoparticles (BNPs) to fabricate a BNP@SNPi substrate. This substrate exhibited a broad reaction surface with significantly enhanced surface-enhanced Raman scattering hotspots, demonstrating excellent Raman performance, along with high reproducibility, sensitivity, and selectivity for TBZ detection. Ultimately, the BNP@SNPi substrate successfully detected TBZ across a wide concentration range in samples of tap water, drinking water, juice, and human serum, with respective limits of detection of 146.5, 245.5, 195.6, and 219.4 pM. This study highlights BNP@SNPi as a promising sensor platform for TBZ detection in diverse environments and contributes to environmental monitoring and bioanalytical studies.
    MeSH term(s) Humans ; Thiabendazole/chemistry ; Spectrum Analysis, Raman/methods ; Reproducibility of Results ; Pesticides ; Metal Nanoparticles/chemistry
    Chemical Substances Thiabendazole (N1Q45E87DT) ; Pesticides
    Language English
    Publishing date 2024-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios14030133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Design of GNSS/IMU Loosely-Coupled Integration Filter for Wearable EPTS of Football Players.

    Kim, Mingu / Park, Chulwoo / Yoon, Jinsung

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 4

    Abstract: This study presents the filter design of GNSS/IMU integration for wearable EPTS (Electronic Performance and Tracking System) of football players. EPTS has been widely used in sports fields recently, and GNSS (Global Navigation Satellite System) and IMU ( ... ...

    Abstract This study presents the filter design of GNSS/IMU integration for wearable EPTS (Electronic Performance and Tracking System) of football players. EPTS has been widely used in sports fields recently, and GNSS (Global Navigation Satellite System) and IMU (Inertial Measurement Unit) in wearable EPTS have been used to measure and provide players' athletic performance data. A sensor fusion technique can be used to provide high-quality analysis data of athletic performance. For this reason, the integration filter of GNSS data and IMU data is designed in this study. The loosely-coupled strategy is considered to integrate GNSS and IMU data considering the specification of the wearable EPTS product. Quaternion is used to estimate a player's attitude to avoid the gimbal lock singularity in this study. Experiment results validate the performance of the proposed GNSS/IMU loosely-coupled integration filter for wearable EPTS of football players.
    MeSH term(s) Football ; Soccer ; Athletic Performance ; Data Accuracy ; Wearable Electronic Devices
    Language English
    Publishing date 2023-02-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23041749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ultra-sensitive SERS detection of perfluorooctanoic acid based on self-assembled p-phenylenediamine nanoparticle complex.

    Park, Hyunjun / Park, Joohyung / Kim, Woochang / Kim, Woong / Park, Jinsung

    Journal of hazardous materials

    2023  Volume 453, Page(s) 131384

    Abstract: PFOA is a representative perfluorinated compound that is used as a surfactant in various industrial fields. However, because PFOA has severe side effects due to its strong toxicity, such as carcinogenesis, liver damage, and immune system damage, it is ... ...

    Abstract PFOA is a representative perfluorinated compound that is used as a surfactant in various industrial fields. However, because PFOA has severe side effects due to its strong toxicity, such as carcinogenesis, liver damage, and immune system damage, it is crucial to enable PFOA detection with high sensitivity. Herein, we developed a perfluorooctanoic acid (PFOA) surface-enhanced Raman scattering (SERS) sensor using self-assembled p-phenylenediamine (SAp-PD) nanoparticles and an Ag SERS substrate. For the ultra-sensitive detection of PFOA, we synthesized and optimized SAp-PD, which shows a decrease in SERS intensities when reacting with PFOA. Using the Ag nanograss SERS substrate, the change in intensity that resulted from the SAp-PD and PFOA reaction was amplified. Consequently, we detected the 1.28 pM (detection limit) of PFOA in distilled water. Moreover, PFOA molecules were successfully detected in samples of the PFOA-coated frying pan and rice extraction at concentrations up to 1.69 nM and 10.3 μM, respectively.
    Language English
    Publishing date 2023-04-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2023.131384
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Safety and efficacy of Xiaoyao-san for the treatment of functional dyspepsia: a systematic review and meta-analysis of randomized controlled trials.

    Ha, Na-Yeon / Lee, Hanul / Jeong, Haein / Ko, Seok-Jae / Park, Jae-Woo / Kim, Jinsung

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1114222

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2023-04-12
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1114222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Chinese herbal medicine as adjuvant treatment for postoperative nausea and vomiting in patients undergoing laparoscopic surgery

    Jinsung Kim / Na-Yeon Ha / Mu-Jin Park

    BMJ Open, Vol 13, Iss

    a protocol for systematic review and meta-analysis

    2023  Volume 6

    Abstract: Introduction Postoperative nausea and vomiting (PONV) is a distressing symptom that patients often complain of even after less invasive surgery such as laparoscopic surgery (LS). If PONV is not well managed, patient recovery and postoperative quality of ... ...

    Abstract Introduction Postoperative nausea and vomiting (PONV) is a distressing symptom that patients often complain of even after less invasive surgery such as laparoscopic surgery (LS). If PONV is not well managed, patient recovery and postoperative quality of life are adversely affected. Although various drugs have been administered to prevent PONV, their effectiveness is limited, and adverse effects are numerous. Although herbal medicines have been widely used to manage various gastrointestinal symptoms, including nausea and vomiting, scientific evidence of their effects is lacking. This protocol is intended for a systematic review to analyse the efficacy and safety of Chinese herbal medicines for PONV after LS through a meta-analysis.Methods and analysis Randomised controlled trials, reported until June 2022, will be retrieved from electronic databases such as Medline, EMBASE and Cochrane Library. We will compare the effects of herbal medicine in patients presenting with PONV after LS with those of Western medicine, placebo and no treatment. If sufficient studies are identified, we will evaluate the combined effects of herbal and Western medicine. The incidence of nausea and vomiting will be considered the primary outcome. Secondary outcomes will include the intensity of complaints, quality of life and incidence of adverse events. Two independent reviewers will collect data based on the Preferred Reporting Items for Systematic Review and Meta-Analyses statement, evaluate the quality of each study using the Cochrane risk-of-bias tool and synthesise the results via meta-analysis, if possible.Ethics and dissemination Ethical approval is not required for this review. The results of this study will be disseminated to peer-reviewed journals and posters.PROSPERO registration number CRD42022345749.
    Keywords Medicine ; R
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Host Subcellular Organelles: Targets of Viral Manipulation.

    Song, Min Seok / Lee, Dong-Kun / Lee, Chung-Young / Park, Sang-Cheol / Yang, Jinsung

    International journal of molecular sciences

    2024  Volume 25, Issue 3

    Abstract: Viruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular ... ...

    Abstract Viruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular machinery and impair homeostasis. Moreover, viral infection alters the cell membrane's structure and composition and induces vesicle formation to facilitate intracellular trafficking of viral components. However, the research focus has predominantly been on the immune response elicited by viruses, often overlooking the significant alterations that viruses induce in cellular organelles. Gaining a deeper understanding of these virus-induced cellular changes is crucial for elucidating the full life cycle of viruses and developing potent antiviral therapies. Exploring virus-induced cellular changes could substantially improve our understanding of viral infection mechanisms.
    MeSH term(s) Humans ; Virus Replication ; Organelles/ultrastructure ; Virus Diseases ; Host-Pathogen Interactions
    Language English
    Publishing date 2024-01-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25031638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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