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Article ; Online: High T(g) bio-based aliphatic polyesters from bicyclic D-mannitol.

Lavilla, Cristina / Alla, Abdelilah / Martínez de Ilarduya, Antxon / Muñoz-Guerra, Sebastián

Biomacromolecules

2013 Volume 14, Issue 3, Page(s) 781–793

Abstract: The carbohydrate-based diol 2,4:3,5-di-O-methylene-d-mannitol (Manx) has been used to obtain ...

Abstract	The carbohydrate-based diol 2,4:3,5-di-O-methylene-d-mannitol (Manx) has been used to obtain aliphatic polyesters. Manx is a symmetric bicyclic compound consisting of two fused 1,3-dioxane rings and bearing two primary hydroxyl groups. In terms of stiffness, it is comparable to the widely known isosorbide, but it affords the additional advantages of being much more reactive in polycondensation and capable of producing stereoregular polymers with fairly high molecular weights. A fully bio-based homopolyester (PManxS) has been synthesized by polycondensation in the melt from dimethyl succinate and Manx. The high thermal stability of PManxS, its relatively high glass transition temperature (Tg = 68 °C) and elastic modulus, and its enhanced sensitivity to the action of lipases point to PManxS as a polyester of exceptional interest for those applications where biodegradability and molecular stiffness are priority requirements. In addition, random copolyesters (PBxManxyS) covering a broad range of compositions have been obtained using mixtures of Manx and 1,4-butanediol in the reaction with dimethyl succinate. All PBxManxyS were semicrystalline and displayed Tg values from -29 to +51 °C steadily increasing with the content in Manx units. The stress-strain behavior of these copolyesters largely depended on their content in Manx and they were enzymatically degraded faster than PBS.
MeSH term(s)	Biocompatible Materials/chemical synthesis ; Bridged Bicyclo Compounds, Heterocyclic/chemical synthesis ; Butylene Glycols/analysis ; Butylene Glycols/chemistry ; Isosorbide/chemistry ; Lipase/metabolism ; Magnetic Resonance Spectroscopy ; Mannitol/analogs & derivatives ; Mannitol/chemical synthesis ; Mannitol/chemistry ; Polyesters/chemistry
Chemical Substances	Biocompatible Materials ; Bridged Bicyclo Compounds, Heterocyclic ; Butylene Glycols ; Polyesters ; Mannitol (3OWL53L36A) ; 1,4-butanediol (7XOO2LE6G3) ; Lipase (EC 3.1.1.3) ; Isosorbide (WXR179L51S)
Language	English
Publishing date	2013-03-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1526-4602
ISSN (online)	1526-4602
DOI	10.1021/bm301854c
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Article ; Online: Phenotypic rate and state are decoupled in response to river-to-lake transitions in cichlid fishes.

Burress, Edward D / Muñoz, Martha M

Evolution; international journal of organic evolution

2023 Volume 77, Issue 11, Page(s) 2365–2377

Abstract: ... frequencies. Lakes may provide ecological opportunity via ecological release (e.g., from predators/competitors ...

Abstract	Geographic access to isolated ecosystems is an important catalyst of adaptive radiation. Cichlid fishes repeatedly colonized rift, crater, and volcanic lakes from surrounding rivers. We test the "lake effect" on the phenotypic rate and state across 253 cichlid species. The rate of evolution was consistently higher (~10-fold) in lakes, and consistent across different dimensions of the phenotype. Rate shifts tended to occur coincident with or immediately following river-to-lake transitions, generally resulting in 2- to 5-fold faster rates than in the founding riverine lineage. By contrast, river- and lake-dwelling cichlids exhibit considerable overlap in phenotypes, generally with less disparity in lakes, but often different evolutionary optima. Taken together, these results suggest that lake radiations rapidly expand into niches largely already represented by ancestral riverine lineages, albeit in different frequencies. Lakes may provide ecological opportunity via ecological release (e.g., from predators/competitors) but need not be coupled with access to novel ecological niches.
MeSH term(s)	Animals ; Lakes ; Phylogeny ; Rivers ; Ecosystem ; Cichlids/genetics ; Phenotype
Language	English
Publishing date	2023-08-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2036375-8
ISSN	1558-5646 ; 0014-3820
ISSN (online)	1558-5646
ISSN	0014-3820
DOI	10.1093/evolut/qpad143
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Article: Adaptación española del General Health Questionnaire (G.H.Q.) de D. P. Goldberg (un método de identificación de casos psiquiátricos en la comunidad.

Muñóz, P E / Vázquez, J L / Rodríguez Insausti, F / Pastrana, E / Varo, J

Archivos de neurobiologia

1979 Volume 42, Issue 2, Page(s) 139–158

Title translation	Spanish adaptation of the General Health Questionnaire (G.H.Q.) of D. P. Goldberg (a method for identifying psychiatric cases in the community).
MeSH term(s)	England ; Humans ; Medical History Taking ; Mental Disorders/diagnosis ; Methods ; Psychiatric Status Rating Scales ; Spain ; Surveys and Questionnaires
Language	Spanish
Publishing date	1979-03
Publishing country	Spain
Document type	Comparative Study ; English Abstract ; Journal Article
ZDB-ID	974866-0
ISSN	0004-0576
ISSN	0004-0576
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Article ; Online: Adipose-tissue regulatory T cells are a consortium of subtypes that evolves with age and diet.

Muñoz-Rojas, Andrés R / Wang, Gang / Benoist, Christophe / Mathis, Diane

Proceedings of the National Academy of Sciences of the United States of America

2024 Volume 121, Issue 4, Page(s) e2320602121

Abstract: ... ...

Abstract	Foxp3
MeSH term(s)	Mice ; Animals ; T-Lymphocytes, Regulatory ; Adipose Tissue/metabolism ; Diet ; Obesity/metabolism ; Mice, Obese ; Inflammation/metabolism
Language	English
Publishing date	2024-01-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2320602121
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Article ; Online: Endoparasitic diversity from the Southern Ocean: is it really low in Antarctic fish?

Muñoz, G / Cartes, F D

Journal of helminthology

2020 Volume 94, Page(s) e180

Abstract: The biodiversity and composition of endoparasites in fish obtained from the Antarctic and subantarctic zones are compared in this study. Several fish were collected in the summer from Antarctica (King George Island) and the Southern Pacific coast (Strait ...

Abstract	The biodiversity and composition of endoparasites in fish obtained from the Antarctic and subantarctic zones are compared in this study. Several fish were collected in the summer from Antarctica (King George Island) and the Southern Pacific coast (Strait of Magellan and Almirante Montt Gulf). This database was complemented with published information on fish endoparasite communities from both zones, with specimens of fish sample size n ≥ 15. Thus, 31 fish species were analysed in this study, which altogether had 79 parasite species. Diversity indices were calculated for the parasite community of each fish species. Then they were compared between the Antarctic and subantarctic zones. Parasite species composition and host specificity (as the number of fish species used by a parasite species) were also analysed and compared between zones. The diversity indices and the abundance of parasites were significantly higher in the Antarctic than the subantarctic fish. Few parasite species (7.6%) were shared between fish from both zones, showing significant differences in parasite composition. Antarctic parasites were less host-specific than subantarctic parasites, which allowed the coexistence of several parasite species in the fish. The high parasite abundance in Antarctic fish could trigger sympatric speciation in certain parasitic lineages or the exploitation of new resources, resulting in more parasite species than those in subantarctic environments. The high abundance of Antarctic parasites implies different methods and rates of transmission than those of subantarctic parasites. In addition, more alternative fish hosts were used by the Antarctic than subantarctic parasites. This altogether indicates that host-parasite interaction dynamics significantly differ between the Antarctic and subantarctic systems.
MeSH term(s)	Animals ; Antarctic Regions ; Biodiversity ; Fish Diseases/parasitology ; Fishes/classification ; Fishes/parasitology ; Host-Parasite Interactions ; Oceans and Seas ; Parasites/classification ; Parasites/isolation & purification
Language	English
Publishing date	2020-08-11
Publishing country	England
Document type	Comparative Study ; Journal Article
ZDB-ID	390188-9
ISSN	1475-2697 ; 0022-149X
ISSN (online)	1475-2697
ISSN	0022-149X
DOI	10.1017/S0022149X20000590
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Article ; Online: Evidence of learning walks related to scorpion home burrow navigation.

Gaffin, Douglas D / Muñoz, Maria G / Hoefnagels, Mariëlle H

The Journal of experimental biology

2022 Volume 225, Issue 12

Abstract: The navigation by chemo-textural familiarity hypothesis (NCFH) suggests that scorpions use their midventral pectines to gather chemical and textural information near their burrows and use this information as they subsequently return home. For NCFH to be ... ...

Abstract	The navigation by chemo-textural familiarity hypothesis (NCFH) suggests that scorpions use their midventral pectines to gather chemical and textural information near their burrows and use this information as they subsequently return home. For NCFH to be viable, animals must somehow acquire home-directed 'tastes' of the substrate, such as through path integration (PI) and/or learning walks. We conducted laboratory behavioral trials using desert grassland scorpions (Paruroctonus utahensis). Animals reliably formed burrows in small mounds of sand we provided in the middle of circular, sand-lined behavioral arenas. We processed overnight infrared video recordings with a MATLAB script that tracked animal movements at 1-2 s intervals. In all, we analyzed the movements of 23 animals, representing nearly 1500 h of video recording. We found that once animals established their home burrows, they immediately made one to several short, looping excursions away from and back to their burrows before walking greater distances. We also observed similar excursions when animals made burrows in level sand in the middle of the arena (i.e. no mound provided). These putative learning walks, together with recently reported PI in scorpions, may provide the crucial home-directed information requisite for NCFH.
MeSH term(s)	Animals ; Sand ; Scorpions
Chemical Substances	Sand
Language	English
Publishing date	2022-06-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218085-6
ISSN	1477-9145 ; 0022-0949
ISSN (online)	1477-9145
ISSN	0022-0949
DOI	10.1242/jeb.243947
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Article ; Online: Healthy Behavior and Sports Drinks: A Systematic Review.

Muñoz-Urtubia, Nicolás / Vega-Muñoz, Alejandro / Estrada-Muñoz, Carla / Salazar-Sepúlveda, Guido / Contreras-Barraza, Nicolás / Castillo, Dante

Nutrients

2023 Volume 15, Issue 13

Abstract: This review article aims to systematically identify the relationship between sports drinks and healthy behavior. This systematic literature review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) ... ...

Abstract	This review article aims to systematically identify the relationship between sports drinks and healthy behavior. This systematic literature review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline criteria, and eligibility criteria were established using the PICOS tool (population, interventions, comparators, outcomes, and study) from about 1000 records of sports drinks articles identified in the various Web of Science Core Collection databases. The literature review stages determined a reduced set of 15 articles relating these drinkable supplements to healthy behavior. This study concludes that water consumption should be emphasized for non-athletes, sports drinks should be labeled to indicate water consumption and carry a warning label, and more randomized clinical trials should be considered to ensure conclusive results for health decision making.
MeSH term(s)	Sports ; Health Behavior ; Databases, Factual
Language	English
Publishing date	2023-06-27
Publishing country	Switzerland
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15132915
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Article: Endoparasitic diversity from the Southern Ocean: is it really low in Antarctic fish?

Muñoz, G / Cartes, F.D

Journal of helminthology. , v. 94

2020

Abstract	The biodiversity and composition of endoparasites in fish obtained from the Antarctic and subantarctic zones are compared in this study. Several fish were collected in the summer from Antarctica (King George Island) and the Southern Pacific coast (Strait of Magellan and Almirante Montt Gulf). This database was complemented with published information on fish endoparasite communities from both zones, with specimens of fish sample size n ≥ 15. Thus, 31 fish species were analysed in this study, which altogether had 79 parasite species. Diversity indices were calculated for the parasite community of each fish species. Then they were compared between the Antarctic and subantarctic zones. Parasite species composition and host specificity (as the number of fish species used by a parasite species) were also analysed and compared between zones. The diversity indices and the abundance of parasites were significantly higher in the Antarctic than the subantarctic fish. Few parasite species (7.6%) were shared between fish from both zones, showing significant differences in parasite composition. Antarctic parasites were less host-specific than subantarctic parasites, which allowed the coexistence of several parasite species in the fish. The high parasite abundance in Antarctic fish could trigger sympatric speciation in certain parasitic lineages or the exploitation of new resources, resulting in more parasite species than those in subantarctic environments. The high abundance of Antarctic parasites implies different methods and rates of transmission than those of subantarctic parasites. In addition, more alternative fish hosts were used by the Antarctic than subantarctic parasites. This altogether indicates that host–parasite interaction dynamics significantly differ between the Antarctic and subantarctic systems.
Keywords	coasts ; databases ; endoparasites ; fish ; host specificity ; host-parasite relationships ; sample size ; species diversity ; summer ; sympatric speciation ; Antarctic region ; Antarctica
Language	English
Dates of publication	2020-0811
Publishing place	Cambridge University Press
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	390188-9
ISSN	1475-2697 ; 0022-149X
ISSN (online)	1475-2697
ISSN	0022-149X
DOI	10.1017/S0022149X20000590
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: A Monte Carlo study on the secondary neutron generation by oxygen ion beams for radiotherapy and its comparison to lighter ions.

Geser, Federico A / Stabilini, Alberto / Christensen, Jeppe B / Muñoz, Iván D / Yukihara, Eduardo G / Jäkel, Oliver / Vedelago, José

Physics in medicine and biology

2024 Volume 69, Issue 1

Abstract: Objective. ...

Abstract	Objective.
MeSH term(s)	Neutrons ; Proton Therapy/methods ; Protons ; Radiotherapy Dosage ; Monte Carlo Method
Chemical Substances	Protons
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Journal Article
ZDB-ID	208857-5
ISSN	1361-6560 ; 0031-9155
ISSN (online)	1361-6560
ISSN	0031-9155
DOI	10.1088/1361-6560/ad0f45
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Article ; Online: Functional Trade-Offs Asymmetrically Promote Phenotypic Evolution.

Burress, Edward D / Muñoz, Martha M

Systematic biology

2022 Volume 72, Issue 1, Page(s) 150–160

Abstract: ... force trade-off reflects a gradient from specialization on capture-intensive (e.g., evasive or buried ... to processing-intensive prey (e.g., attached or shelled), respectively. The velocity extreme of the trade-off is ... system as force-modified oral jaws are adapted for prey that requires intensive processing (e.g., algae ...

Abstract	Trade-offs are thought to bias evolution and are core features of many anatomical systems. Therefore, trade-offs may have far-reaching macroevolutionary consequences, including patterns of morphological, functional, and ecological diversity. Jaws, like many complex anatomical systems, are comprised of elements involved in biomechanical trade-offs. We test the impact of a core mechanical trade-off, the transmission of velocity versus force (i.e., mechanical advantage), on rates of jaw evolution in Neotropical cichlids. Across 130 species representing a wide array of feeding ecologies, we find that the velocity-force trade-off impacts the evolution of the surrounding jaw system. Specifically, rates of jaw evolution are faster at functional extremes than in more functionally intermediate or unspecialized jaws. Yet, surprisingly, the effect on jaw evolution is uneven across the extremes of the velocity-force continuum. Rates of jaw evolution are 4- to 10-fold faster in velocity-modified jaws, whereas force-modified jaws are 7- to 18-fold faster, compared to unspecialized jaws, depending on the extent of specialization. Further, we find that a more extreme mechanical trade-off resulted in faster rates of jaw evolution. The velocity-force trade-off reflects a gradient from specialization on capture-intensive (e.g., evasive or buried) to processing-intensive prey (e.g., attached or shelled), respectively. The velocity extreme of the trade-off is characterized by large magnitudes of trait change leading to functionally divergent specialists and ecological stasis. By contrast, the force extreme of the trade-off is characterized by enhanced ecological lability made possible by phenotypes more readily co-opted for different feeding ecologies. This asymmetry of macroevolutionary outcomes along each extreme is likely the result of an enhanced utility of the pharyngeal jaw system as force-modified oral jaws are adapted for prey that requires intensive processing (e.g., algae, detritus, and mollusks). The velocity-force trade-off, a fundamental feature of many anatomical systems, promotes rapid phenotypic evolution of the surrounding jaw system in a canonical continental adaptive radiation. Considering that the velocity-force trade-off is an inherent feature of all jaw systems that involve a lower element that rotates at a joint, spanning the vast majority of vertebrates, our results may be widely applicable across the tree of life. [Adaptive radiation; constraint; decoupling; jaws; macroevolution; specialization.].
MeSH term(s)	Animals ; Phylogeny ; Biomechanical Phenomena ; Jaw/anatomy & histology ; Cichlids/genetics ; Phenotype ; Biological Evolution
Language	English
Publishing date	2022-08-10
Publishing country	England
Document type	Journal Article
ZDB-ID	1482572-7
ISSN	1076-836X ; 1063-5157
ISSN (online)	1076-836X
ISSN	1063-5157
DOI	10.1093/sysbio/syac058
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