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  1. Article: STATISTICAL MODELS FOR COVID-19 INCIDENCE, CUMULATIVE PREVALENCE, AND

    Jewell, Nicholas P

    Journal of the American Statistical Association

    2021  Volume 116, Issue 536, Page(s) 1578–1582

    Language English
    Publishing date 2021-12-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2064981-2
    ISSN 1537-274X ; 0162-1459 ; 0003-1291
    ISSN (online) 1537-274X
    ISSN 0162-1459 ; 0003-1291
    DOI 10.1080/01621459.2021.1983436
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: On the role of statisticians and modelers in responding to AIDS and COVID-19.

    Jewell, Britta L / Jewell, Nicholas P

    Statistics in medicine

    2021  Volume 40, Issue 11, Page(s) 2530–2535

    MeSH term(s) Acquired Immunodeficiency Syndrome/drug therapy ; Acquired Immunodeficiency Syndrome/epidemiology ; COVID-19 ; Humans ; Pandemics ; Research Personnel ; SARS-CoV-2
    Language English
    Publishing date 2021-05-07
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 843037-8
    ISSN 1097-0258 ; 0277-6715
    ISSN (online) 1097-0258
    ISSN 0277-6715
    DOI 10.1002/sim.8943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: On the use of the reproduction number for SARS-CoV-2: Estimation, misinterpretations and relationships with other ecological measures.

    Jewell, Nicholas P / Lewnard, Joseph A

    Journal of the Royal Statistical Society. Series A, (Statistics in Society)

    2022  

    Abstract: The basic reproduction number, ...

    Abstract The basic reproduction number,
    Language English
    Publishing date 2022-06-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1490715-X
    ISSN 1467-985X ; 0964-1998 ; 0035-9238
    ISSN (online) 1467-985X
    ISSN 0964-1998 ; 0035-9238
    DOI 10.1111/rssa.12860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Statistics for epidemiology

    Jewell, Nicholas P.

    (Texts in statistical science)

    2004  

    Author's details Nicholas P. Jewell
    Series title Texts in statistical science
    Keywords Epidemiologic Methods ; Statistics / methods ; Epidemiologie
    Subject Krankheitsverbreitung
    Language English
    Size XIV, 333 S. : Ill., graph. Darst.
    Publisher Chapman & Hall/CRC
    Publishing place Boca Raton u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT013811743
    ISBN 1-58488-433-9 ; 978-1-58488-433-0
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: The role of firearm and alcohol availability in firearm suicide: A population-based weighted case-control study.

    Pear, Veronica A / Wintemute, Garen J / Jewell, Nicholas P / Ahern, Jennifer

    Health & place

    2023  Volume 79, Page(s) 102969

    Abstract: Firearm availability has been linked to firearm self-harm, but the joint relationship with alcohol availability, while supported by theory, has not been examined. This study sought to quantify the separate and joint relations of community firearm and ... ...

    Abstract Firearm availability has been linked to firearm self-harm, but the joint relationship with alcohol availability, while supported by theory, has not been examined. This study sought to quantify the separate and joint relations of community firearm and alcohol availability with individual-level risk of (fatal and nonfatal) firearm self-harm. We conducted a case-control study of California residents, 2005-2015, using statewide mortality, hospital, firearm transfer, and alcohol license data. We estimated monthly marginal risk differences per 100,000 in the overall population and in white men aged 50+ under various hypothetical changes to firearm and alcohol availability and assessed additive interactions using case-control-weighted g-computation. In the overall population, non-pawn shop firearm dealer density was associated with firearm self-harm (RD: 0.02, 95% CI: 0.003, 0.04) but pawn shop firearm dealer and alcohol outlet densities were not. Secondary analyses revealed a relationship between firearm sales density and firearm self-harm (RD: 0.07, 95% CI: 0.04, 0.10). There were no additive interactions between measures of firearm and alcohol availability. Among older white men, generally the same exposures were related to self-harm as in the overall population, but point estimates were substantially larger. Findings suggest community-level approaches to reducing firearm sales may help mitigate suicide risk.
    MeSH term(s) Male ; Humans ; Homicide ; Case-Control Studies ; Suicide ; Firearms ; Violence
    Language English
    Publishing date 2023-01-19
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1262540-1
    ISSN 1873-2054 ; 1353-8292
    ISSN (online) 1873-2054
    ISSN 1353-8292
    DOI 10.1016/j.healthplace.2023.102969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Predictive Mathematical Models of the COVID-19 Pandemic: Underlying Principles and Value of Projections.

    Jewell, Nicholas P / Lewnard, Joseph A / Jewell, Britta L

    JAMA

    2020  Volume 323, Issue 19, Page(s) 1893–1894

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/mortality ; Forecasting ; Humans ; Models, Theoretical ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/mortality ; SARS-CoV-2 ; United States/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-04-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2020.6585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Caution Warranted: Using the Institute for Health Metrics and Evaluation Model for Predicting the Course of the COVID-19 Pandemic.

    Jewell, Nicholas P / Lewnard, Joseph A / Jewell, Britta L

    Annals of internal medicine

    2020  Volume 173, Issue 3, Page(s) 226–227

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/mortality ; Forecasting ; Humans ; Models, Statistical ; Pandemics ; Pneumonia, Viral/mortality ; Quality Indicators, Health Care ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-14
    Publishing country United States
    Document type Editorial
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/M20-1565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Vaccine Effectiveness Studies in the Field.

    Evans, Stephen J W / Jewell, Nicholas P

    The New England journal of medicine

    2021  Volume 385, Issue 7, Page(s) 650–651

    MeSH term(s) Humans ; Vaccination ; Viral Vaccines
    Chemical Substances Viral Vaccines
    Language English
    Publishing date 2021-07-21
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe2110605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Analysis of counts for cluster randomized trials: Negative controls and test-negative designs.

    Dufault, Suzanne M / Jewell, Nicholas P

    Statistics in medicine

    2020  Volume 39, Issue 10, Page(s) 1429–1439

    Abstract: In cluster randomized trials (CRTs), the outcome of interest is often a count at the cluster level. This occurs, for example, in evaluating an intervention with the outcome being the number of infections of a disease such as HIV or dengue or the number ... ...

    Abstract In cluster randomized trials (CRTs), the outcome of interest is often a count at the cluster level. This occurs, for example, in evaluating an intervention with the outcome being the number of infections of a disease such as HIV or dengue or the number of hospitalizations in the cluster. Standard practice analyzes these counts through cluster outcome rates using an appropriate denominator (eg, population size). However, such denominators are sometimes unknown, particularly when the counts depend on a passive community surveillance system. We consider direct comparison of the counts without knowledge of denominators, relying on randomization to balance denominators. We also focus on permutation tests to allow for small numbers of randomized clusters. However, such approaches are subject to bias when there is differential ascertainment of counts across arms, a situation that may occur in CRTs that cannot implement blinded interventions. We suggest the use of negative control counts as a method to remove, or reduce, this bias, discussing the key properties necessary for an effective negative control. A current example of such a design is the recent extension of test-negative designs to CRTs testing community-level interventions. Via simulation, we compare the performance of new and standard estimators based on CRTs with negative controls to approaches that only use the original counts. When there is no differential ascertainment by intervention arm, the count-only approaches perform comparably to those using debiasing negative controls. However, under even modest differential ascertainment, the count-only estimators are no longer reliable.
    MeSH term(s) Bias ; Cluster Analysis ; Computer Simulation ; Humans ; Randomized Controlled Trials as Topic ; Research Design
    Language English
    Publishing date 2020-01-30
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 843037-8
    ISSN 1097-0258 ; 0277-6715
    ISSN (online) 1097-0258
    ISSN 0277-6715
    DOI 10.1002/sim.8488
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Natural history of diseases: Statistical designs and issues.

    Jewell, Nicholas P

    Clinical pharmacology and therapeutics

    2016  Volume 100, Issue 4, Page(s) 353–361

    Abstract: Understanding the natural history of a disease is an important prerequisite for designing studies that assess the impact of interventions, both chemotherapeutic and environmental, on the initiation and expression of the condition. Identification of ... ...

    Abstract Understanding the natural history of a disease is an important prerequisite for designing studies that assess the impact of interventions, both chemotherapeutic and environmental, on the initiation and expression of the condition. Identification of biomarkers that mark disease progression may provide important indicators for drug targets and surrogate outcomes for clinical trials. However, collecting and visualizing data on natural history is challenging, in part, because disease processes are complex and evolve in different chronological periods for different subjects. Various epidemiological designs are used to elucidate components of the natural history process. We briefly discuss statistical issues, limitations, and challenges associated with various epidemiological designs.
    MeSH term(s) Disease Progression ; Epidemiologic Methods ; Humans ; Statistics as Topic
    Language English
    Publishing date 2016-08-18
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 123793-7
    ISSN 1532-6535 ; 0009-9236
    ISSN (online) 1532-6535
    ISSN 0009-9236
    DOI 10.1002/cpt.423
    Database MEDical Literature Analysis and Retrieval System OnLINE

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