LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 3230

Search options

  1. Article: Pharmacological Mechanism of Shen Huang Chong Ji for Treating Alzheimer's Disease Based on Network Pharmacology and Experimental Validation.

    Tang, Lei / Liu, Jing / Xu, Xiaozhuo / Zhao, Juan / Han, Xu

    Evidence-based complementary and alternative medicine : eCAM

    2022  Volume 2022, Page(s) 9243348

    Abstract: The traditional Chinese medicine (TCM) formula, Sheng Huang Chong Ji (SHCJ) is largely applied ...

    Abstract The traditional Chinese medicine (TCM) formula, Sheng Huang Chong Ji (SHCJ) is largely applied for treating Alzheimer's disease (AD), but not much is known regarding its active compounds, molecular targets, and mechanism of action. The current study aimed to predict the potential molecular mechanism of SHCJ against AD based on network pharmacology combined with in vitro validation. Using public databases, SHCJ's active compounds, their potential targets, and AD-related genes were screened, while Cytoscape Version 3.7.2 was used to build protein-protein interaction (PPI) and compound-disease-target (C-D-T) networks. Analysis of enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and Gene Ontology (GO) terms was then carried out in
    Language English
    Publishing date 2022-05-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2022/9243348
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Pharmacological Mechanism of Shen Huang Chong Ji for Treating Alzheimer’s Disease Based on Network Pharmacology and Experimental Validation

    Lei Tang / Jing Liu / Xiaozhuo Xu / Juan Zhao / Xu Han

    Evidence-Based Complementary and Alternative Medicine, Vol

    2022  Volume 2022

    Abstract: The traditional Chinese medicine (TCM) formula, Sheng Huang Chong Ji (SHCJ) is largely applied ...

    Abstract The traditional Chinese medicine (TCM) formula, Sheng Huang Chong Ji (SHCJ) is largely applied for treating Alzheimer’s disease (AD), but not much is known regarding its active compounds, molecular targets, and mechanism of action. The current study aimed to predict the potential molecular mechanism of SHCJ against AD based on network pharmacology combined with in vitro validation. Using public databases, SHCJ’s active compounds, their potential targets, and AD-related genes were screened, while Cytoscape Version 3.7.2 was used to build protein–protein interaction (PPI) and compound-disease-target (C-D-T) networks. Analysis of enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and Gene Ontology (GO) terms was then carried out in R 4.0.2, including associated packages. Subsequently, molecular docking analysis was performed with AutoDock Vina 1.1.2, with intro experiments involving SH-SY5Y cells used to further investigate the mechanism of SHCJ against AD. Finally, a total of 56 active compounds of SHCJ and 192 SHCJ-AD-related targets were identified. Quercetin was identified as the top potential candidate agent. HSP90AA1, AKT1, and MAPK1 represent potential therapeutic targets. The PI3K-Akt signaling pathway potentially represents a core one mediating the effects of SHCJ against AD. Additionally, molecular docking analysis indicated that quercetin could combine well with AKT1 and multiple apoptosis-related target genes. During cell experiments, a significant increase in cell viability along with a decrease in Aβ25-35-induced apoptosis was observed after treatment with SHCJ. Furthermore, SHCJ significantly increased the phosphorylation of PI3K and Akt while reversing Aβ25-35-induced apoptosis-related protein expression downregulation.
    Keywords Other systems of medicine ; RZ201-999
    Subject code 500
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Book: Bao chong bing ying xiang zhen duan tu pu

    Tang, Guibo

    2015  

    Title variant Imaging diagnosis of hydatid disease
    Author's details zhu bian Tang Guibo
    MeSH term(s) Echinococcosis/diagnosis ; Multimodal Imaging/methods
    Language Chinese
    Size 14, 254 pages :, illustrations, portrait
    Edition Di 1 ban.
    Document type Book
    ISBN 9787117215299 ; 7117215291
    Database Catalogue of the US National Library of Medicine (NLM)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Factors associated with utilization of reproductive healthcare services among migrant women workers in Chong Qing, China.

    Su, Shu / Zhang, Fan / Liu, Qin / Wang, Yang / Wen, Jing / Tang, Xiaojun / Zhang, Lei

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2014  Volume 127, Issue 1, Page(s) 66–68

    Abstract: ... in Chong Qing, China, and provide suggestions to improve the utilization of these services by young women ... policy-makers in Chong Qing, China.: Results: Women workers seldom visited hospitals and did so only ...

    Abstract Objective: To investigate the use of reproductive healthcare services among migrant women workers in Chong Qing, China, and provide suggestions to improve the utilization of these services by young women.
    Methods: In a qualitative interview-based study between March, 2013 and June, 2013, personal in-depth interviews were conducted among young women workers, factory doctors, healthcare service providers, and policy-makers in Chong Qing, China.
    Results: Women workers seldom visited hospitals and did so only when their pain became unbearable. The workers' use of reproductive healthcare services was particularly influenced by the high cost of hospitalization and long waiting periods. Factory doctors could only solve minor problems. Public healthcare providers stated that migrant women had a higher morbidity rate from reproductive tract infections as compared with local women. The policy-makers considered that the health system was beneficial to women's reproductive health; however, few workers had good comprehension of government policies.
    Conclusion: Migrant women workers are vulnerable owing to lack of reproductive health care. The government and both social and health enterprise should consider the convenience of these women and the affordability of treatments when formulating reproductive healthcare policies. Effective measures should be taken to improve the use of these services by migrant women workers.
    MeSH term(s) Adolescent ; Adult ; China ; Female ; Humans ; Reproductive Health Services/utilization ; Transients and Migrants/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2014-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1016/j.ijgo.2014.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 355: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 183: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Book: Shi yong bao chong bing ying xiang xue

    Tang, Guibo

    Practical echinococcosis imaging

    2013  

    Title variant Practical echinococcosis imaging
    Author's details Tang Guibo zhu bian
    MeSH term(s) Echinococcosis/physiopathology ; Multimodal Imaging/methods
    Language Chinese
    Size 8, 136 pages :, illustrations
    Edition Di 1 ban.
    Document type Book
    ISBN 9787117178907 ; 7117178906
    Database Catalogue of the US National Library of Medicine (NLM)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Book: Zhongguo ji sheng chong bing fang zhi yu yan jiu

    Tang, Linhua

    2012  

    Title variant Parasitic disease control and research in China
    Author's details Tang Linhua, Xu Longqi, Chen Yingdan zhu bian
    MeSH term(s) Parasitic Diseases/prevention & control ; Parasitic Diseases/epidemiology ; Antiparasitic Agents/therapeutic use
    Keywords China
    Language Chinese
    Size 2 v. :, ill.
    Edition Di 1 ban.
    Publisher Beijing ke xue ji shu chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787530449134 ; 7530449133
    Database Catalogue of the US National Library of Medicine (NLM)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Book: Ren wen jing shen zhi chong jian

    Tang, Junyi

    (Tang jun yi quan ji : 唐君毅全集 ; / Tang jun yi zhu ; 5)

    1989  

    Series title Tang jun yi quan ji : 唐君毅全集
    / Tang jun yi zhu ; 5
    Keywords East and west ; Humanism
    Language Chinese
    Size 14, 603 S., 22 cm
    Edition 1 ban 2 shua
    Publisher Tai wan xue sheng shu ju
    Publishing place Tai bei shi
    Document type Book
    Note In chines. Schr. ; Includes bibliographical references
    ISBN 9571501883 ; 9571510211 ; 9789571501888 ; 9789571510217
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book: Zhongguo yuan lin zhu yao jie chong

    Tang, Fangde

    (Shanxi nong xue yuan ke yan cheng guo cong kan zhi 1)

    1977  

    Title variant Scale insects of horticulture and forest of China
    Author's details Tang Fangde
    Series title Shanxi nong xue yuan ke yan cheng guo cong kan zhi 1
    Keywords Scale insects
    Language Chinese ; English ; Latin
    Dates of publication 1977-1986
    Size 3 v. :, ill. ;, 21-26 cm.
    Publisher Shenyang Shi yuan lin ke xue yan jiu suo ; Shanxi nong xue yuan
    Publishing place Liaoning
    Document type Book
    Note Table of contents and abstracts also in English. ; Nomenclature in Chinese and Latin.
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Fitness to drive after trigger or carpal tunnel release surgery: perceptions of patients versus clinicians.

    Tang, Camelia Qian Ying / Lai, Sean Han Sheng / Lee, Ellen Yutan / Foo, Anthony / Chong, Alphonsus Khin Sze

    Singapore medical journal

    2024  

    Language English
    Publishing date 2024-03-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 604319-7
    ISSN 2737-5935 ; 0037-5675
    ISSN (online) 2737-5935
    ISSN 0037-5675
    DOI 10.4103/singaporemedj.SMJ-2021-424
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 589: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Book: Chong yin ji xi xian zhi

    Tang, Zizong

    1963  

    Title variant Ji xi xian zhi ; 績溪縣志
    Institution Tai bei shi ji xi tong xiang hui
    臺北市績溪同鄉會
    Author's details Tai bei shi ji xi tong xiang hui zeng fu bian; tang zi zong deng bian zuan
    Keywords Jixi Xian (China)
    Language Chinese
    Dates of publication 1963-1810
    Size 3, 778 pages, [38] pages of plates, illustrations, folded maps, portraits, 21 cm
    Publisher Gai tong xiang hui
    Publishing place Tai bei shi
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top