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  1. Article ; Online: Fungal Infections Other Than Invasive Aspergillosis in COVID-19 Patients.

    Basile, Kerri / Halliday, Catriona / Kok, Jen / Chen, Sharon C-A

    Journal of fungi (Basel, Switzerland)

    2022  Volume 8, Issue 1

    Abstract: Invasive fungal disease (IFD) associated with Coronavirus Disease 2019 (COVID-19) has focussed predominantly on invasive pulmonary aspergillosis. However, increasingly emergent are non- ...

    Abstract Invasive fungal disease (IFD) associated with Coronavirus Disease 2019 (COVID-19) has focussed predominantly on invasive pulmonary aspergillosis. However, increasingly emergent are non-
    Language English
    Publishing date 2022-01-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8010058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Fungal Infections Other Than Invasive Aspergillosis in COVID-19 Patients

    Kerri Basile / Catriona Halliday / Jen Kok / Sharon C-A. Chen

    Journal of Fungi, Vol 8, Iss 58, p

    2022  Volume 58

    Abstract: Invasive fungal disease (IFD) associated with Coronavirus Disease 2019 (COVID-19) has focussed predominantly on invasive pulmonary aspergillosis. However, increasingly emergent are non- Aspergillus fungal infections including candidiasis, mucormycosis, ... ...

    Abstract Invasive fungal disease (IFD) associated with Coronavirus Disease 2019 (COVID-19) has focussed predominantly on invasive pulmonary aspergillosis. However, increasingly emergent are non- Aspergillus fungal infections including candidiasis, mucormycosis, pneumocystosis, cryptococcosis, and endemic mycoses. These infections are associated with poor outcomes, and their management is challenged by delayed diagnosis due to similarities of presentation to aspergillosis or to non-specific features in already critically ill patients. There has been a variability in the incidence of different IFDs often related to heterogeneity in patient populations, diagnostic protocols, and definitions used to classify IFD. Here, we summarise and address knowledge gaps related to the epidemiology, risks, diagnosis, and management of COVID-19-associated fungal infections other than aspergillosis.
    Keywords COVID-19 ; SARS-CoV-2 ; fungal infections ; non- Aspergillus fungi ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Fulminant

    Colaco, Clinton M G / Basile, Kerri / Draper, Jenny / Ferguson, Patricia E

    BMJ case reports

    2021  Volume 14, Issue 1

    Abstract: This case represents a rare fulminant course of fried-rice associated food poisoning in an immunocompetent person due to pre-formed exotoxin produced ... ...

    Abstract This case represents a rare fulminant course of fried-rice associated food poisoning in an immunocompetent person due to pre-formed exotoxin produced by
    MeSH term(s) Acetylcysteine/therapeutic use ; Acidosis/physiopathology ; Acidosis/therapy ; Adult ; Anti-Arrhythmia Agents/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Arrhythmias, Cardiac/physiopathology ; Arrhythmias, Cardiac/therapy ; Bacillus cereus/genetics ; Bacillus cereus/isolation & purification ; Blood Coagulation Disorders/physiopathology ; Blood Coagulation Disorders/therapy ; Blood Transfusion ; Brain Diseases ; Continuous Renal Replacement Therapy ; Exotoxins/genetics ; Fatal Outcome ; Female ; Foodborne Diseases/diagnosis ; Foodborne Diseases/microbiology ; Foodborne Diseases/physiopathology ; Foodborne Diseases/therapy ; Free Radical Scavengers/therapeutic use ; Humans ; Immunocompetence ; Liver Failure/physiopathology ; Liver Failure/therapy ; Multiple Organ Failure/physiopathology ; Multiple Organ Failure/therapy ; Plasmapheresis ; Renal Insufficiency/physiopathology ; Renal Insufficiency/therapy ; Rhabdomyolysis/physiopathology ; Rhabdomyolysis/therapy ; Sepsis/physiopathology ; Sepsis/therapy ; Shock/physiopathology ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Whole Genome Sequencing
    Chemical Substances Anti-Arrhythmia Agents ; Anti-Bacterial Agents ; Exotoxins ; Free Radical Scavengers ; Acetylcysteine (WYQ7N0BPYC)
    Language English
    Publishing date 2021-01-18
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-238716
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Arthropod-Borne Flaviviruses in Pregnancy.

    Howard-Jones, Annaleise R / Pham, David / Sparks, Rebecca / Maddocks, Susan / Dwyer, Dominic E / Kok, Jen / Basile, Kerri

    Microorganisms

    2023  Volume 11, Issue 2

    Abstract: Flaviviruses are a diverse group of enveloped RNA viruses that cause significant clinical manifestations in the pregnancy and postpartum periods. This review highlights the epidemiology, pathophysiology, clinical features, diagnosis, and prevention of ... ...

    Abstract Flaviviruses are a diverse group of enveloped RNA viruses that cause significant clinical manifestations in the pregnancy and postpartum periods. This review highlights the epidemiology, pathophysiology, clinical features, diagnosis, and prevention of the key arthropod-borne flaviviruses of concern in pregnancy and the neonatal period-Zika, Dengue, Japanese encephalitis, West Nile, and Yellow fever viruses. Increased disease severity during pregnancy, risk of congenital malformations, and manifestations of postnatal infection vary widely amongst this virus family and may be quite marked. Laboratory confirmation of infection is complex, especially due to the reliance on serology for which flavivirus cross-reactivity challenges diagnostic specificity. As such, a thorough clinical history including relevant geographic exposures and prior vaccinations is paramount for accurate diagnosis. Novel vaccines are eagerly anticipated to ameliorate the impact of these flaviviruses, particularly neuroinvasive disease manifestations and congenital infection, with consideration of vaccine safety in pregnant women and children pivotal. Moving forward, the geographical spread of flaviviruses, as for other zoonoses, will be heavily influenced by climate change due to the potential expansion of vector and reservoir host habitats. Ongoing 'One Health' engagement across the human-animal-environment interface is critical to detect and responding to emergent flavivirus epidemics.
    Language English
    Publishing date 2023-02-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11020433
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  5. Article ; Online: Prolonged PCR positivity in elderly patients infected with SARS-CoV-2.

    Howard-Jones, Annaleise R / Maddocks, Susan / Basile, Kerri / Dwyer, Dominic E / Branley, James / Kok, Jen

    Pathology

    2021  Volume 53, Issue 7, Page(s) 914–916

    MeSH term(s) Aged ; COVID-19 ; Humans ; Nucleic Acid Amplification Techniques ; Polymerase Chain Reaction ; RNA, Viral ; SARS-CoV-2
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2021-09-23
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 7085-3
    ISSN 1465-3931 ; 0031-3025
    ISSN (online) 1465-3931
    ISSN 0031-3025
    DOI 10.1016/j.pathol.2021.08.004
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 723: Show issues Location:
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  6. Article ; Online: Emergent Omicron BR.2.1 sublineage of SARS-CoV-2 in New South Wales, Australia: a subvariant with high fitness but without increased disease severity.

    Howard-Jones, Annaleise R / Arnott, Alicia / Draper, Jenny / Gall, Mailie / Ellis, Sally / Marris, Kelsi / Selvey, Christine / Basile, Kerri / Dwyer, Dominic E / Sintchenko, Vitali / Kok, Jen

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2023  Volume 130, Page(s) 38–41

    Abstract: Objectives: To describe the epidemiology and impact of Omicron BR.2.1, an emergent SARS-CoV-2 Omicron BA.2.75 sublineage displaying high fitness compared to other cocirculating subvariants in New South Wales, Australia.: Methods: From September 01 to ...

    Abstract Objectives: To describe the epidemiology and impact of Omicron BR.2.1, an emergent SARS-CoV-2 Omicron BA.2.75 sublineage displaying high fitness compared to other cocirculating subvariants in New South Wales, Australia.
    Methods: From September 01 to November 26, 2022, 4971 SARS-CoV-2 consensus genomes from unique patients were generated, and correlated with international travel and reinfection history, and admission to the intensive care unit.
    Results: BR.2.1 became the predominant variant by late November, and was responsible for a significantly higher proportion of community-acquired cases during the study period (55.1% vs 38.4%, P < 0.001). Reinfections (defined as occurring between 6 and 24 weeks after a prior diagnosis of COVID-19) were significantly higher among BR.2.1 compared to non-BR.2.1 infected persons (17.0% vs 6.0%, P < 0.001). BR.2.1 cases were also significantly younger compared to non-BR.2.1 (median age 48 years (interquartile range [IQR] 32) vs 53 years (IQR 32), P = 0.004). The proportion of patients admitted to the intensive care unit with BR.2.1 was not significantly higher than other subvariants (2.3% vs 2.0%, P = 0.717).
    Conclusion: Having emerged locally within New South Wales, BR.2.1 caused a significant number of SARS-CoV-2 reinfections, but with disease severity comparable with other currently circulating lineages. Given its rapid rise in prevalence, BR.2.1 has the potential to become established internationally.
    MeSH term(s) Humans ; Adult ; New South Wales/epidemiology ; SARS-CoV-2 ; Reinfection ; COVID-19/diagnosis ; COVID-19/epidemiology ; Australia ; Patient Acuity
    Chemical Substances carboxymethyl-dextran-A2-gadolinium-DOTA
    Language English
    Publishing date 2023-02-25
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2023.02.019
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4516: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: Zika virus: what, where from and where to?

    Basile, Kerri / Kok, Jen / Dwyer, Dominic E

    Pathology

    2017  Volume 49, Issue 7, Page(s) 698–706

    Abstract: The significance of Zika virus as a clinically significant flavivirus has previously been under-recognised, until extensive outbreaks in Yap in 2007, French Polynesia in 2013 and the Americas since 2015. Although Zika virus infection is commonly ... ...

    Abstract The significance of Zika virus as a clinically significant flavivirus has previously been under-recognised, until extensive outbreaks in Yap in 2007, French Polynesia in 2013 and the Americas since 2015. Although Zika virus infection is commonly asymptomatic or mild, emerging evidence suggests a strong link to microcephaly in babies and Guillain-Barré syndrome in adults. This article reviews the epidemiology, geographic distribution, basic virology, transmission, clinical presentation, potential complications, laboratory diagnosis, treatment and prevention of Zika virus infection. Education on mosquito avoidance measures and vector control efforts currently remain key to reducing risk of transmission, whilst further research is underway to develop antiviral therapies and vaccines.
    Language English
    Publishing date 2017-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 7085-3
    ISSN 1465-3931 ; 0031-3025
    ISSN (online) 1465-3931
    ISSN 0031-3025
    DOI 10.1016/j.pathol.2017.08.002
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    Zs.A 723: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Article ; Online: A laboratory framework for ongoing optimization of amplification-based genomic surveillance programs.

    Lam, Connie / Johnson-Mackinnon, Jessica / Basile, Kerri / Fong, Winkie / Suster, Carl J E / Gall, Mailie / Agius, Jessica / Chandra, Shona / Draper, Jenny / Martinez, Elena / Drew, Alexander / Wang, Qinning / Chen, Sharon C / Kok, Jen / Dwyer, Dominic E / Sintchenko, Vitali / Rockett, Rebecca J

    Microbiology spectrum

    2023  Volume 11, Issue 6, Page(s) e0220223

    Abstract: Importance: This study provides a laboratory framework to ensure ongoing relevance and performance of amplification-based whole genome sequencing to strengthen public health surveillance during extended outbreaks or pandemics. The framework integrates ... ...

    Abstract Importance: This study provides a laboratory framework to ensure ongoing relevance and performance of amplification-based whole genome sequencing to strengthen public health surveillance during extended outbreaks or pandemics. The framework integrates regular reviews of the performance of a genomic surveillance system and highlights the importance of ongoing monitoring and the identification and implementation of improvements to whole genome sequencing methods to enhance public health responses to pathogen outbreaks.
    MeSH term(s) Genomics ; Public Health ; Disease Outbreaks ; Whole Genome Sequencing/methods ; Public Health Surveillance
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.02202-23
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  9. Article ; Online: Point-of-care diagnostics for respiratory viral infections.

    Basile, Kerri / Kok, Jen / Dwyer, Dominic E

    Expert review of molecular diagnostics

    2017  Volume 18, Issue 1, Page(s) 75–83

    Abstract: Introduction: Successful treatment outcomes for viral respiratory tract infections presenting from primary health care to quaternary hospitals will only be achieved with rapid, sensitive and specific identification of pathogens to allow effective ... ...

    Abstract Introduction: Successful treatment outcomes for viral respiratory tract infections presenting from primary health care to quaternary hospitals will only be achieved with rapid, sensitive and specific identification of pathogens to allow effective pathogen-specific antiviral therapy and infection control measures. Areas covered: This review aims to explore the different point-of-care tests currently available to diagnose viral respiratory tract infections, discuss the advantages and limitations of point-of-care testing, and provide insights into the future of point-of-care tests. The following databases were searched: Medline (January 1996 to 30 September 2017) and Embase (1988 to 30 September 2017), using the following keywords: 'point of care', 'respiratory virus', 'influenza', 'RSV', 'diagnostics', 'nucleic acid test' and 'PCR'. Expert commentary: Viral respiratory tract infections cause significant morbidity and mortality worldwide, and point-of-care tests are facilitating the rapid identification of the pathogen responsible given the similarities in clinical presentation.
    MeSH term(s) Humans ; Nucleic Acid Amplification Techniques ; Point-of-Care Testing ; Quality Assurance, Health Care ; Reproducibility of Results ; Respiratory Tract Infections/diagnosis ; Respiratory Tract Infections/virology ; Sensitivity and Specificity ; Virus Diseases/diagnosis ; Virus Diseases/virology ; Viruses/genetics
    Keywords covid19
    Language English
    Publishing date 2017-12-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2112530-2
    ISSN 1744-8352 ; 1473-7159
    ISSN (online) 1744-8352
    ISSN 1473-7159
    DOI 10.1080/14737159.2018.1419065
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    Zs.A 6073: Show issues Location:
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  10. Article ; Online: The impact of influenza virus infection in pregnancy.

    Somerville, Lucy K / Basile, Kerri / Dwyer, Dominic E / Kok, Jen

    Future microbiology

    2018  Volume 13, Page(s) 263–274

    Abstract: Data from previous seasonal epidemics and pandemics have confirmed that pregnant women are at increased risk for severe influenza virus infection. Complications including fetal loss, higher rates of hospitalization and maternal death are most notable ... ...

    Abstract Data from previous seasonal epidemics and pandemics have confirmed that pregnant women are at increased risk for severe influenza virus infection. Complications including fetal loss, higher rates of hospitalization and maternal death are most notable during the late gestational period. Antiviral therapy and influenza vaccination are recommended in pregnant women as both are effective and safe. This review discusses the epidemiology, pathophysiology, treatment and prevention of influenza virus infection in pregnancy, with a focus on recent developments.
    MeSH term(s) Animals ; Antiviral Agents/therapeutic use ; Cytokines/immunology ; Disease Models, Animal ; Female ; Humans ; Influenza A Virus, H1N1 Subtype/physiology ; Influenza Vaccines/administration & dosage ; Influenza, Human/drug therapy ; Influenza, Human/epidemiology ; Influenza, Human/physiopathology ; Influenza, Human/prevention & control ; Pandemics ; Pregnancy ; Pregnancy Complications, Infectious/virology ; Risk ; Treatment Outcome
    Chemical Substances Antiviral Agents ; Cytokines ; Influenza Vaccines
    Language English
    Publishing date 2018-01-11
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1746-0921
    ISSN (online) 1746-0921
    DOI 10.2217/fmb-2017-0096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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