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  1. Article ; Online: Corals nitrogen and carbon isotopic signatures alters under Artificial Light at Night (ALAN).

    Ayalon, Inbal / Avisar, Dror / Jechow, Andreas / Levy, Oren

    The Science of the total environment

    2024  Volume 920, Page(s) 170513

    Abstract: This study examines the impact of Artificial Light at Night (ALAN) on two coral species, Acropora eurystoma and Pocillopora damicornis, in the Gulf of Aqaba/Eilat Red Sea, assessing their natural isotopic responses to highlight changes in energy and ... ...

    Abstract This study examines the impact of Artificial Light at Night (ALAN) on two coral species, Acropora eurystoma and Pocillopora damicornis, in the Gulf of Aqaba/Eilat Red Sea, assessing their natural isotopic responses to highlight changes in energy and nutrient sourcing due to sensory light pollution. Our findings indicate significant disturbances in photosynthetic processes in Acropora eurystoma, as evidenced by shifts in δ
    MeSH term(s) Animals ; Anthozoa ; Nitrogen ; Ecosystem ; Carbon Isotopes ; Light Pollution ; Carbon ; Coral Reefs
    Chemical Substances Nitrogen (N762921K75) ; Carbon Isotopes ; Carbon (7440-44-0)
    Language English
    Publishing date 2024-02-13
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.170513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Flatfoot in Africa, the cirripede

    Simon-Blecher, Noa / Jacob, Avi / Levy, Oren / Appelbaum, Lior / Elbaz-Ifrah, Shiran / Achituv, Yair

    PeerJ

    2021  Volume 9, Page(s) e11710

    Abstract: Barnacles of the ... ...

    Abstract Barnacles of the genus
    Language English
    Publishing date 2021-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703241-3
    ISSN 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.11710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Post COVID-19 Acute Myocardial Infarction Rebound.

    Fardman, Alexander / Oren, Daniel / Berkovitch, Anat / Segev, Amit / Levy, Yuval / Beigel, Roy / Matetzky, Shlomi

    The Canadian journal of cardiology

    2020  Volume 36, Issue 11, Page(s) 1832.e15–1832.e16

    MeSH term(s) Aged ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Female ; Hospitalization/statistics & numerical data ; Humans ; Israel/epidemiology ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Pandemics/statistics & numerical data ; Patient Admission/statistics & numerical data ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-28
    Publishing country England
    Document type Letter ; Observational Study
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2020.08.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Phage Therapy Potentiates Second-Line Antibiotic Treatment against Pneumonic Plague.

    Vagima, Yaron / Gur, David / Aftalion, Moshe / Moses, Sarit / Levy, Yinon / Makovitzki, Arik / Holtzman, Tzvi / Oren, Ziv / Segula, Yaniv / Fatelevich, Ella / Tidhar, Avital / Zauberman, Ayelet / Rotem, Shahar / Mamroud, Emanuelle / Steinberger-Levy, Ida

    Viruses

    2022  Volume 14, Issue 4

    Abstract: Plague pandemics and outbreaks have killed millions of people during the history of humankind. The disease, caused by the ... ...

    Abstract Plague pandemics and outbreaks have killed millions of people during the history of humankind. The disease, caused by the bacteria
    MeSH term(s) Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacteriophages ; Disease Models, Animal ; Humans ; Mice ; Phage Therapy ; Plague/drug therapy ; Yersinia pestis
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-03-26
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14040688
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Antiscalants used in the desalination industry impact the physiology of the coral Montipora capricornis.

    Marques, Joseane A / Gafni, Almog / Adler, Osher / Levy, Oren / Bar-Zeev, Edo

    Water research

    2022  Volume 229, Page(s) 119411

    Abstract: Many coral reefs are found in arid and semi-arid regions that often face severe water scarcity and depend on seawater desalination for freshwater supply. Alongside freshwater production, desalination plants discharge brine waste into the sea. Brine ... ...

    Abstract Many coral reefs are found in arid and semi-arid regions that often face severe water scarcity and depend on seawater desalination for freshwater supply. Alongside freshwater production, desalination plants discharge brine waste into the sea. Brine includes various chemicals (e.g., antiscalants) that may harm the coastal environment. Although widely used, little is known about the ecotoxicological effects of antiscalants (AS) on hard corals. This study compared the impacts of polyphosphonate-based and polymer-based ASs on the coral Montipora capricornis. After two weeks of exposure, we determined the effects of AS on coral physiology, symbiotic microalgae, and associated bacteria, using various analytical approaches such as optical coherence tomography, pulse amplitude modulated fluorometry, and oxidative stress biomarkers. Both ASs reduced polyp activity (∼25%) and caused tissue damage (30% and 41% for polymer and polyphosphonate based AS, respectively). In addition, exposure to polyphosphonate-based AS decreased the abundance of endosymbiotic algae (39%) and upregulated the antioxidant capacity of the animal host (45%). The microalgal symbionts were under oxidative stress, with increased levels of antioxidant capacity and oxidative damage (a 2-fold increase compared to the control). Interestingly, exposure to AS enhanced the numbers of associated bacteria (∼40% compared to the control seawater) regardless of the AS type. Our results introduce new insights into the effects of brine on the physiology of hard corals, highlighting that choosing AS type must be examined according to the receiving ecosystem.
    MeSH term(s) Animals ; Anthozoa/physiology ; Antioxidants ; Bacteria ; Coral Reefs ; Ecosystem
    Chemical Substances Antioxidants ; brine ; polyphosphonate (38720-58-0)
    Language English
    Publishing date 2022-11-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 202613-2
    ISSN 1879-2448 ; 0043-1354
    ISSN (online) 1879-2448
    ISSN 0043-1354
    DOI 10.1016/j.watres.2022.119411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Impacts of Desalination Brine Discharge on Benthic Ecosystems.

    Sirota, Ryan / Winters, Gidon / Levy, Oren / Marques, Joseane / Paytan, Adina / Silverman, Jack / Sisma-Ventura, Guy / Rahav, Eyal / Antler, Gilad / Bar-Zeev, Edo

    Environmental science & technology

    2024  Volume 58, Issue 13, Page(s) 5631–5645

    Abstract: Seawater reverse osmosis (SWRO) desalination facilities produce freshwater and, at the same time, discharge hypersaline brine that often includes various chemical additives such as antiscalants and coagulants. This dense brine can sink to the sea bottom ... ...

    Abstract Seawater reverse osmosis (SWRO) desalination facilities produce freshwater and, at the same time, discharge hypersaline brine that often includes various chemical additives such as antiscalants and coagulants. This dense brine can sink to the sea bottom and creep over the seabed, reaching up to 5 km from the discharge point. Previous reviews have discussed the effects of SWRO desalination brine on various marine ecosystems, yet little attention has been paid to the impacts on benthic habitats. This review comprehensibly discusses the effects of SWRO brine discharge on marine benthic fauna and flora. We review previous studies that indicated a suite of impacts by SWRO brine on benthic organisms, including bacteria, seagrasses, polychaetes, and corals. The effects within the discharge mixing zones range from impaired activities and morphological deformations to changes in the community composition. Recent modeling work demonstrated that brine could spread over the seabed, beyond the mixing zone, for up to several tens of kilometers and impair nutrient fluxes from the sediment to the water column. We also provide a possible perspective on brine's impact on the biogeochemical process within the mixing zone subsurface. Desalination brine can infiltrate into the sandy bottom around the discharge area due to gravity currents. Accumulation of brine and associated chemical additives, such as polyphosphonate-based antiscalants and ferric-based coagulants in the porewater, may change the redox zones and, hence, impact biogeochemical processes in sediments. With the demand for drinking water escalating worldwide, the volumes of brine discharge are predicted to triple during the current century. Future efforts should focus on the development and operation of viable technologies to minimize the volumes of brine discharged into marine environments, along with a change to environmentally friendly additives. However, the application of these technologies should be partly subsidized by governmental stakeholders to safeguard coastal ecosystems around desalination facilities.
    MeSH term(s) Ecosystem ; Salinity ; Water Purification ; Seawater/chemistry ; Salts
    Chemical Substances brine ; Salts
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.3c07748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Safety of Repeated Administration of Xenogeneic Human Apoptotic State (Allocetra-OTS) in Sprague Dawley Rats.

    Ankri, Chen / Hershkovitz, Oren / Hershkovitz, Liat / Brami, Meital / Levy, Ronnie / Sarig, Hadar / Souli, Einat / Reicher, Barak / Amor-Baroukh, Veronique / Mevorach, Dror / Nyska, Abraham

    Pharmaceutics

    2024  Volume 16, Issue 3

    Abstract: Apoptotic cells possess immunomodulatory effects that can be utilized to treat imbalanced immune conditions. Information on the preclinical safety of such treatment is sparse. In this study, the safety of apoptotic cells (Allocetra-OTS) was assessed in a ...

    Abstract Apoptotic cells possess immunomodulatory effects that can be utilized to treat imbalanced immune conditions. Information on the preclinical safety of such treatment is sparse. In this study, the safety of apoptotic cells (Allocetra-OTS) was assessed in a GLP toxicological study on Sprague Dawley rats. Three doses of Allocetra-OTS or vehicle were administered intravenously (IV) for 3 consecutive days. Animals in the main study were sacrificed on day 4, while animals from the recovery groups were kept for 14 or 28 days. Allocetra-OTS was well tolerated, and no adverse effects were observed in terms of body weight, clinical signs, food consumption, or ophthalmologic observation. Thus, the No Observed Adverse Effect Level (NOAEL) dose was determined as the highest dose administered. An observed elevation in immune cells was suspected to be due to Allocetra-OTS, similarly to other clinical chemistry parameters; however, it was resolved in the recovery phases. Splenomegaly and dose-related extramedullary hematopoiesis (EMH) in the red pulp were observed, with no adverse events, and were considered to be a normal and expected reaction following the IV administration of cell-based therapies. In conclusion, under the conditions of this study, Allocetra-OTS was concluded to be safe, further supporting its potential candidacy for clinical studies.
    Language English
    Publishing date 2024-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics16030426
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Case report: Anorexia nervosa and unspecified restricting-type eating disorder in Jewish ultra-orthodox religious males, leading to severe physical and psychological morbidity.

    Laufer, Sofia / Herman, Estee / Serfaty, David / Latzer, Yael / Ashkenazi, Rachel / Attias, Orna / Oren, Sinai / Shimomi, Meirav / Uziel, Moria / Enoch-Levy, Adi / Witztum, Eliezer / Stein, Daniel

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 966935

    Abstract: Background: Young Jewish Ultra-Orthodox women usually show less disturbances in body image and eating in comparison to less religious communities. By contrast, problems with eating are highly unknown and unrecognized in Jewish Ultra-Orthodox males.: ... ...

    Abstract Background: Young Jewish Ultra-Orthodox women usually show less disturbances in body image and eating in comparison to less religious communities. By contrast, problems with eating are highly unknown and unrecognized in Jewish Ultra-Orthodox males.
    Aim: To investigate whether in Ultra-Orthodox males, restricting-type AN (AN-R) with highly obsessional physical activity and unspecified restricting eating disorder (ED) in the context of obsessive-compulsive disorder (OCD) would lead to severe physical and emotional morbidity.
    Results: The study included two groups: the first, 3 adolescents with AN-R developing severely increased ritualized obsessional physical activity in addition to restricting eating, requiring inpatient treatment because of severe bradycardia. These youngsters ignored the severity of their obsessional physical activity, continuing with it in hospital despite their grave medical condition. One student began extensive training for triathlon, whereas another student, upon remitting from AN, developed severe muscle dysmorphia. These findings suggest that young Ultra-Orthodox males with AN may develop obsessional physical activity to increase their muscle mass rather than to lose weight Another four Jewish Ultra-Orthodox males developed malnutrition in the context of severe OCD, with no evidence of dieting or body-image disturbances. These individuals developed highly obsessional adherence to different Jewish religious rules, including prolonged praying, asceticism, and overvalued strict adherence to Jewish Kashrut rules of eating, leading in all cases to severe food restriction. They were highly unaware of their severe weight loss and required hospitalization because of severe physical disturbances associated with malnutrition. Moreover, most did not cooperate with their treatment, and their ED-related obsessionality was mostly resistant to psychopharmacotherapy.
    Conclusion: Owing to their highly ritualistic rigid way of life, combined with the need for excellency in studying, Jewish Ultra-Orthodox adolescent males with AN might be at a specific risk of developing severe physical disturbances if their illness is associated with highly perfectionistic obsessional physical activity. Second, Jewish Ultra-Orthodox religious males with OCD might be at a specific risk for severe undernutrition, as their rigid relentless observance of Jewish everyday laws might highly interfere with their eating.
    Language English
    Publishing date 2023-04-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.966935
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Post COVID-19 Acute Myocardial Infarction Rebound

    Fardman, Alexander / Oren, Daniel / Berkovitch, Anat / Segev, Amit / Levy, Yuval / Beigel, Roy / Matetzky, Shlomi

    Canadian Journal of Cardiology

    2020  Volume 36, Issue 11, Page(s) 1832.e15–1832.e16

    Keywords Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2020.08.016
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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