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  1. Article ; Online: Reply to Wei Liu, Xiaoping Liu, Sheng Li's Letter to the Editor, re: Robert A. Huddart, Emma Hall, Rebecca Lewis, et al. Patient-reported Quality of Life Outcomes in Patients Treated for Muscle-invasive Bladder Cancer with Radiotherapy ± Chemotherapy in the BC2001 Phase III Randomised Controlled Trial. Eur Urol 2020;77:260-8.

    Huddart, Robert / Hall, Emma / Lewis, Rebecca / Porta, Nuria / Hussain, Syed A / James, Nicholas D

    European urology

    2020  Volume 77, Issue 6, Page(s) e156–e157

    MeSH term(s) Humans ; Patient Reported Outcome Measures ; Quality of Life ; Urinary Bladder Neoplasms/drug therapy
    Language English
    Publishing date 2020-03-10
    Publishing country Switzerland
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2020.02.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: From Bench to Booth: Examining Hair-Cell Regeneration Through an Audiologist's Scope.

    Lewis, Rebecca M

    Journal of the American Academy of Audiology

    2022  Volume 32, Issue 10, Page(s) 654–660

    Abstract: Damage to auditory hair cells is a key feature of sensorineural hearing loss due to aging, noise exposure, or ototoxic drugs. Though hair-cell loss is permanent in humans, research in bird species led to the discovery that analogous hair cells of the ... ...

    Abstract Damage to auditory hair cells is a key feature of sensorineural hearing loss due to aging, noise exposure, or ototoxic drugs. Though hair-cell loss is permanent in humans, research in bird species led to the discovery that analogous hair cells of the avian basilar papilla are able to regenerate after being damaged by ototoxic agents. Regeneration appears to occur through a combination of the mitotic expansion of a precursor population of supporting cells and direct transdifferentiation of supporting cells into functioning hair cells. This review will synthesize the relevant anatomy and pathophysiology of sensorineural hearing loss, the historical observations that led to the genesis of the hair-cell regeneration field, and perspectives on initial human hair-cell regeneration trials.
    MeSH term(s) Audiologists ; Hair Cells, Auditory/physiology ; Hearing Loss, Sensorineural/therapy ; Humans ; Regeneration/physiology
    Language English
    Publishing date 2022-05-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1132599-9
    ISSN 2157-3107 ; 1050-0545
    ISSN (online) 2157-3107
    ISSN 1050-0545
    DOI 10.1055/s-0041-1731700
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Aggression, rank and power: why hens (and other animals) do not always peck according to their strength.

    Lewis, Rebecca J

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences

    2022  Volume 377, Issue 1845, Page(s) 20200434

    Abstract: Thorlief Schjelderup-Ebbe's seminal paper on the 'pecking' order of chickens inspired numerous ethologists to research and debate the phenomenon of dominance. The expansion of dominance to the broader concept of power facilitated disentangling aggression, ...

    Abstract Thorlief Schjelderup-Ebbe's seminal paper on the 'pecking' order of chickens inspired numerous ethologists to research and debate the phenomenon of dominance. The expansion of dominance to the broader concept of power facilitated disentangling aggression, strength, rank and power. Aggression is only one means of coercing other individuals, and can sometimes highlight a lack of power. The fitness advantages of aggression may only outweigh the costs during periods of uncertainty. Effective instruments of power also include incentives and refusals to act. Moreover, the stability of the power relationship might vary with the instruments used if different means of power vary in the number and types of outcomes achieved, as well as the speed of accomplishing those outcomes. In well-established relationships, actions or physiological responses in the subordinate individual may even be the only indicator of a power differential. A focus on strength, aggression and fighting provides an incomplete understanding of the power landscape that individuals actually experience. Multiple methods for constructing hierarchies exist but greater attention to the implications of the types of data used in these constructions is needed. Many shifts in our understanding of power were foreshadowed in Schjelderup-Ebbe's discussion about deviations from the linear hierarchy in chickens. This article is part of the theme issue 'The centennial of the pecking order: current state and future prospects for the study of dominance hierarchies'.
    MeSH term(s) Aggression ; Animals ; Behavior, Animal ; Chickens ; Female ; Social Dominance ; Uncertainty
    Language English
    Publishing date 2022-01-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 208382-6
    ISSN 1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
    ISSN (online) 1471-2970
    ISSN 0080-4622 ; 0264-3839 ; 0962-8436
    DOI 10.1098/rstb.2020.0434
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Too much of a good thing? Iatrogenic Cushing syndrome secondary to excessive topical steroid use in lichen sclerosus.

    Psomadakis, Cristina / Tweddell, Rebecca / Lewis, Fiona

    Clinical and experimental dermatology

    2023  Volume 48, Issue 4, Page(s) 429–430

    MeSH term(s) Humans ; Female ; Lichen Sclerosus et Atrophicus/drug therapy ; Cushing Syndrome/chemically induced ; Vulvar Lichen Sclerosus/drug therapy ; Steroids/therapeutic use ; Iatrogenic Disease ; Administration, Topical
    Chemical Substances Steroids
    Language English
    Publishing date 2023-02-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1093/ced/llac097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Consistency in Verreaux's sifaka home range and core area size despite seasonal variation in resource availability as assessed by Enhanced Vegetation Index (EVI).

    Axel, Anne C / Harshbarger, Brynn M / Lewis, Rebecca J / Tecot, Stacey R

    American journal of primatology

    2024  , Page(s) e23617

    Abstract: Primates are adept at dealing with fluctuating availability of resources and display a range of responses to minimize the effects of food scarcity. An important component of primate conservation is to understand how primates adapt their foraging and ... ...

    Abstract Primates are adept at dealing with fluctuating availability of resources and display a range of responses to minimize the effects of food scarcity. An important component of primate conservation is to understand how primates adapt their foraging and ranging patterns in response to fluctuating food resources. Animals optimize resource acquisition within the home range through the selection of resource-bearing patches and choose between contrasting foraging strategies (resource-maximizing vs. area-minimizing). Our study aimed to characterize the foraging strategy of a folivorous primate, Verreaux's sifaka (Propithecus verreauxi), by evaluating whether group home range size varied between peak and lean leaf seasons within a seasonally dry tropical forest in Madagascar. We hypothesized that Verreaux's sifaka used the resource maximization strategy to select high-value resource patches so that during periods of resource depression, the home range area did not significantly change in size. We characterized resource availability (i.e., primary productivity) by season at Kirindy Mitea National Park using remotely-sensed Enhanced Vegetation Index data. We calculated group home ranges using 10 years of focal animal sampling data collected on eight groups using both 95% and 50% kernel density estimation. We used area accumulation curves to ensure each group had an adequate number of locations to reach seasonal home range asymptotes. Neither 95% home ranges nor 50% core areas differed across peak and lean leaf resource seasons, supporting the hypothesis that Verreaux's sifaka use a resource maximization strategy. With a better understanding of animal space use strategies, managers can model anticipated changes under environmental and/or anthropogenic resource depression scenarios. These findings demonstrate the value of long-term data for characterizing and understanding foraging and ranging patterns. We also illustrate the benefits of using satellite data for characterizing food resources for folivorous primates.
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1495834-X
    ISSN 1098-2345 ; 0275-2565
    ISSN (online) 1098-2345
    ISSN 0275-2565
    DOI 10.1002/ajp.23617
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: From Bench to Booth: Examining Hair Cell Regeneration Through an Audiologist's Scope

    Lewis, Rebecca M.

    Journal of the American Academy of Audiology

    2021  Volume 32, Issue 10, Page(s) 654–660

    Abstract: Damage to auditory hair cells is a key feature of sensorineural hearing loss due to aging, noise exposure, or ototoxic drugs. Though hair cell loss is permanent in humans, research in bird species led to the discovery that analogous hair cells of the ... ...

    Abstract Damage to auditory hair cells is a key feature of sensorineural hearing loss due to aging, noise exposure, or ototoxic drugs. Though hair cell loss is permanent in humans, research in bird species led to the discovery that analogous hair cells of the avian basilar papilla are able to regenerate after being damaged by ototoxic agents. Regeneration appears to occur through a combination of the mitotic expansion of a precursor population of supporting cells and direct transdifferentiation of supporting cells into functioning hair cells. This review will synthesize the relevant anatomy and pathophysiology of sensorineural hearing loss, the historical observations that led to the genesis of the hair cell regeneration field, and perspectives on initial human hair cell regeneration trials.
    Keywords hearing ; auditory ; cochlear implants
    Language English
    Publishing date 2021-11-01
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 1132599-9
    ISSN 2157-3107 ; 1050-0545
    ISSN (online) 2157-3107
    ISSN 1050-0545
    DOI 10.1055/s-0041-1731700
    Database Thieme publisher's database

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  7. Article ; Online: Subordination signals improve the quality of social relationships in Verreaux's Sifaka: Implications for the evolution of power structures and social complexity.

    Lewis, Rebecca J

    American journal of physical anthropology

    2019  Volume 169, Issue 4, Page(s) 599–607

    Abstract: Objectives: Unidirectional dominance-related signals can be used to communicate submission (an immediate behavioral response) or subordination (the status of an established relationship). Subordination signals are defined as emitted during peaceful ... ...

    Abstract Objectives: Unidirectional dominance-related signals can be used to communicate submission (an immediate behavioral response) or subordination (the status of an established relationship). Subordination signals are defined as emitted during peaceful interactions and are hypothesized to be critical for the evolution of social complexity and robust power structures because they reduce uncertainty in social relationships. The chatter vocalization in Verreaux's sifaka (Propithecus verreauxi) is a unidirectional submissive signal. I tested the hypothesis that chatter vocalizations can signal subordination and thereby reduce agonism in a dyad.
    Materials and methods: I examined 780 chatters from 18 dyads collected over 881 observation hours on four groups of sifaka in Kirindy Forest, Madagascar.
    Results: Sifaka emitted 63% of chatters in the peaceful context. Peaceful chatters significantly predicted grooming rate, fighting rate, reconciliation, and proportion of wins in a dyad but did not predict time in proximity. Dyad-type significantly predicted the frequency of peaceful chatters, with intrasexual dyads exhibiting chatters in peaceful contexts more often than intersexual dyads.
    Discussion: Sifaka communicate both submission and subordination with chatter vocalizations. Subordination signaling increased tolerance and affiliation. It reduced conflicts and the probability dominant individuals usurped resources. Moreover, intrasexual power may be more institutionalized than intersexual power in sifaka. The finding of complex and cognitively demanding social communication in a lemur with low levels of cooperation (1) challenges previous assumptions that the evolution of social complexity is dependent on frequent triadic interactions and high levels of cooperation, and (2) highlights the need for taxonomic diversity in studies of social complexity.
    MeSH term(s) Animals ; Anthropology, Physical ; Female ; Grooming/physiology ; Indriidae/physiology ; Madagascar ; Male ; Social Behavior ; Social Dominance ; Vocalization, Animal/physiology
    Language English
    Publishing date 2019-06-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.23876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Female Power: A New Framework for Understanding "Female Dominance" in Lemurs.

    Lewis, Rebecca J

    Folia primatologica; international journal of primatology

    2019  Volume 91, Issue 1, Page(s) 48–68

    Abstract: Female dominance is often associated with lemurs. However, consensus does not exist among primatologists on how to define, measure, or explain female dominance. This review explores the utility of applying a broader concept of power to understanding ... ...

    Abstract Female dominance is often associated with lemurs. However, consensus does not exist among primatologists on how to define, measure, or explain female dominance. This review explores the utility of applying a broader concept of power to understanding lemur intersexual relationships. In this framework, power is defined as arising from an asymmetry in a dyadic relationship and can be divided into 2 types: dominance and leverage. Intersexual asymmetries based upon females having superior fighting ability are considered female dominance. However, economic power also exists, and females with resource-based power exhibit female leverage. Additionally, power has 4 characteristics (base, means, amount, and scope) that describe the precise nature of observed phenomena. This article utilizes the 4 characteristics outlined in the power framework to review the existing "female dominance" literature for lemurs and highlights the value of adopting both an expanded concept of power and a more precise language. By placing the multiple phenomena currently labeled under the single term "female dominance" within the power framework, much of the confusion disappears. Thus, not only is the debate reframed, facilitating endeavors to find evolutionary explanations, but the uniqueness of female power in lemurs can be determined empirically rather than by definition.
    MeSH term(s) Animals ; Biological Evolution ; Female ; Sex Factors ; Social Dominance ; Strepsirhini/physiology ; Strepsirhini/psychology
    Language English
    Publishing date 2019-08-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2041-2
    ISSN 1421-9980 ; 0015-5713
    ISSN (online) 1421-9980
    ISSN 0015-5713
    DOI 10.1159/000500443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Letter to Editor: Our concerns about HRT not having a priority as a treatment for osteoporosis in the NOGG guidelines.

    Newson, Louise / Ball, Sarah / Lewis, Rebecca

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

    2022  Volume 34, Issue 4, Page(s) 815–816

    MeSH term(s) Humans ; Osteoporosis/drug therapy ; Osteoporotic Fractures/etiology ; Osteoporotic Fractures/prevention & control
    Language English
    Publishing date 2022-12-28
    Publishing country England
    Document type Letter
    ZDB-ID 1064892-6
    ISSN 1433-2965 ; 0937-941X
    ISSN (online) 1433-2965
    ISSN 0937-941X
    DOI 10.1007/s00198-022-06619-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Executive Function Skills Are Linked to Restricted and Repetitive Behaviors: Three Correlational Meta Analyses.

    Iversen, Rebecca Kvisler / Lewis, Charlie

    Autism research : official journal of the International Society for Autism Research

    2021  Volume 14, Issue 6, Page(s) 1163–1185

    Abstract: There is a consensus on the centrality of restricted and repetitive behaviors (RRBs) in the diagnosis of Autism Spectrum Disorder (ASD), yet the origins of these behaviors are still debated. We reconsider whether executive function (EF) accounts of RRBs ... ...

    Abstract There is a consensus on the centrality of restricted and repetitive behaviors (RRBs) in the diagnosis of Autism Spectrum Disorder (ASD), yet the origins of these behaviors are still debated. We reconsider whether executive function (EF) accounts of RRBs should be revisited. EF deficits and high levels of RRBs are often pronounced in individuals with ASD and are also prevalent in young typically developing children. Despite this, the evidence is mixed, and there has been no systematic attempt to evaluate the relationship across studies and between task batteries. We examine recent evidence, and in three highly powered random-effects analyses (N = 2964), examine the strength of the association between RRB levels and performance on set shifting, inhibitory control, and parental-report based EF batteries. The analyses confirm significant associations between high levels of the behaviors and poor EF skills. Moreover, the associations remained stable across typical development and in individuals with ASD and across different types of EF measures. These meta-analyses consolidate recent evidence identifying that cognitive mechanisms correlate with high RRBs that are seen in individuals with ASD, as well as in typical development. We propose that the EF account may be critical for guiding future interventions in ASD research. LAY SUMMARY: Restricted and repetitive behaviors (RRBs) are diagnostic criteria for Autism yet also common in typical development, and if they persist over time some can have a negative impact on learning and social acceptance. The present meta-analyses found that high levels of RRBs related to poor performance on set-shifting and inhibitory control tasks, as well as high ratings on parental report scales. Future studies should create interventions that aim to improve these skills as they may help manage challenging RRBs.
    MeSH term(s) Autism Spectrum Disorder ; Autistic Disorder ; Child ; Cognition ; Executive Function ; Humans ; Meta-Analysis as Topic ; Parents
    Language English
    Publishing date 2021-01-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2481338-2
    ISSN 1939-3806 ; 1939-3792
    ISSN (online) 1939-3806
    ISSN 1939-3792
    DOI 10.1002/aur.2468
    Database MEDical Literature Analysis and Retrieval System OnLINE

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