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Article ; Online: In Vitro Inhibitory Effect of Some Secondary Metabolites Extract from Ocimum basilicum and Salvia officinalis Against Fusarium oxysporum f.sp albedinis of Phoenix dactylifera. L.

Bouderba, Nora Nahal / Khalid, Khalid Mohamed / Kadi, Hamid

2022 Volume 194, Issue 12, Page(s) 5655–5665

Abstract: Fusarium of date palm is a vascular fusariosis caused by a telluric fungus Fusarium oxysporum f.sp ... albedinis (F.O.A) which affects the best date varieties in Algeria. Several medicinal plants are adapted ... the antifungal effect of the aqueous extract of these plants against Fusarium oxysporum f.sp. albedinis isolated ...

Abstract	Fusarium of date palm is a vascular fusariosis caused by a telluric fungus Fusarium oxysporum f.sp. albedinis (F.O.A) which affects the best date varieties in Algeria. Several medicinal plants are adapted with the climatic complexity of the Saharan region, among these plants in the south-west of Algeria Salvia officinalis and Ocimum basilicum. The aim of this work is to study the antifungal effect of flavonoid extracts from Salvia officinalis and Ocimum basilicum leaves by the technique described by Bouchelta et al. (2005), as well the antifungal effect of the aqueous extract of these plants against Fusarium oxysporum f.sp. albedinis isolated from the grove of Igli. The evaluation of the antifungal activity revealed a slight mycelial growth anti-proportional to the concentration of flavonoid extract added to the culture medium with an inhibition index of 73.04% at the concentration 3.17 μg/ml and 57.42% at the concentration 1.13 µg/ml for flavonoids extract of Ocimum basilicum and Salvia officinalis, respectively. In addition, the aqueous extract revealed an inhibition index of 35.15% at the concentration of 0.33 mg/ml and 10.54% at the concentration of 3.92 mg/ml for Salvia officinalis and Ocimum basilicum, respectively.
MeSH term(s)	Fusarium/physiology ; Ocimum basilicum ; Phoeniceae ; Salvia officinalis ; Antifungal Agents ; Plants, Medicinal ; Flavonoids/pharmacology
Chemical Substances	Antifungal Agents ; Flavonoids
Language	English
Publishing date	2022-07-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	392344-7
ISSN	1559-0291 ; 0273-2289
ISSN (online)	1559-0291
ISSN	0273-2289
DOI	10.1007/s12010-022-04067-4
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Article ; Online: In Vitro Inhibitory Effect of Some Secondary Metabolites Extract from Ocimum basilicum and Salvia officinalis Against Fusarium oxysporum f.sp albedinis of Phoenix dactylifera. L

Bouderba, Nora Nahal / Khalid, Khalid Mohamed / Kadi, Hamid

Appl Biochem Biotechnol. 2022 Dec., v. 194, no. 12 p.5655-5665

2022

Abstract	Fusarium of date palm is a vascular fusariosis caused by a telluric fungus Fusarium oxysporum f.sp. albedinis (F.O.A) which affects the best date varieties in Algeria. Several medicinal plants are adapted with the climatic complexity of the Saharan region, among these plants in the south-west of Algeria Salvia officinalis and Ocimum basilicum. The aim of this work is to study the antifungal effect of flavonoid extracts from Salvia officinalis and Ocimum basilicum leaves by the technique described by Bouchelta et al. (2005), as well the antifungal effect of the aqueous extract of these plants against Fusarium oxysporum f.sp. albedinis isolated from the grove of Igli. The evaluation of the antifungal activity revealed a slight mycelial growth anti-proportional to the concentration of flavonoid extract added to the culture medium with an inhibition index of 73.04% at the concentration 3.17 μg/ml and 57.42% at the concentration 1.13 µg/ml for flavonoids extract of Ocimum basilicum and Salvia officinalis, respectively. In addition, the aqueous extract revealed an inhibition index of 35.15% at the concentration of 0.33 mg/ml and 10.54% at the concentration of 3.92 mg/ml for Salvia officinalis and Ocimum basilicum, respectively.
Keywords	Fusarium oxysporum ; Ocimum basilicum ; Phoenix dactylifera ; Salvia officinalis ; antifungal properties ; culture media ; flavonoids ; fungi ; mycelium ; secondary metabolites ; Algeria
Language	English
Dates of publication	2022-12
Size	p. 5655-5665.
Publishing place	Springer US
Document type	Article ; Online
ZDB-ID	392344-7
ISSN	0273-2289
ISSN	0273-2289
DOI	10.1007/s12010-022-04067-4
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Article ; Online: Fabrication and characterization of 3D-printed composite scaffolds of coral-derived hydroxyapatite nanoparticles/polycaprolactone/gelatin carrying doxorubicin for bone tissue engineering.

Kadi, Fatima / Dini, Ghasem / Poursamar, S Ali / Ejeian, Fatemeh

Journal of materials science. Materials in medicine

2024 Volume 35, Issue 1, Page(s) 7

Abstract: In this study, nanocomposite scaffolds of hydroxyapatite (HA)/polycaprolactone (PCL)/gelatin (Gel) with varying amounts of HA (42-52 wt. %), PCL (42-52 wt. %), and Gel (6 wt. %) were 3D printed. Subsequently, a scaffold with optimal mechanical properties ...

Abstract	In this study, nanocomposite scaffolds of hydroxyapatite (HA)/polycaprolactone (PCL)/gelatin (Gel) with varying amounts of HA (42-52 wt. %), PCL (42-52 wt. %), and Gel (6 wt. %) were 3D printed. Subsequently, a scaffold with optimal mechanical properties was utilized as a carrier for doxorubicin (DOX) in the treatment of bone cancer. For this purpose, HA nanoparticles were first synthesized by the hydrothermal conversion of Acropora coral and characterized by using different techniques. Also, a compression test was performed to investigate the mechanical properties of the fabricated scaffolds. The mineralization of the optimal scaffold was determined by immersing it in simulated body fluid (SBF) solution for 28 days, and the biocompatibility was investigated by seeding MG-63 osteoblast-like cells on it after 1-7 days. The obtained results showed that the average size of the synthesized HA particles was about 80 nm. The compressive modulus and strength of the scaffold with 47 wt. % HA was reported to be 0.29 GPa and 9.9 MPa, respectively, which was in the range of trabecular bones. In addition, the scaffold surface was entirely coated with an apatite layer after 28 days of soaking in SBF. Also, the efficiency and loading percentage of DOX were obtained as 30.8 and 1.6%, respectively. The drug release behavior was stable for 14 days. Cytotoxicity and adhesion evaluations showed that the fabricated scaffold had no negative effects on the viability of MG-63 cells and led to their proliferation during the investigated period. From these results, it can be concluded that the HA/PCL/Gel scaffold prepared in this study, in addition to its drug release capability, has good bioactivity, mechanical properties, and biocompatibility, and can be considered a suitable option for bone tumor treatment.
MeSH term(s)	Animals ; Durapatite ; Gelatin ; Tissue Engineering ; Anthozoa ; Doxorubicin ; Printing, Three-Dimensional ; Polyesters
Chemical Substances	Durapatite (91D9GV0Z28) ; polycaprolactone (24980-41-4) ; Gelatin (9000-70-8) ; Doxorubicin (80168379AG) ; Polyesters
Language	English
Publishing date	2024-01-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	1031752-1
ISSN	1573-4838 ; 0957-4530
ISSN (online)	1573-4838
ISSN	0957-4530
DOI	10.1007/s10856-024-06779-x
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Article ; Online: Vilazodone Alleviates Neurogenesis-Induced Anxiety in the Chronic Unpredictable Mild Stress Female Rat Model: Role of Wnt/β-Catenin Signaling.

El-Kadi, Rana A / AbdelKader, Noha F / Zaki, Hala F / Kamel, Ahmed S

Molecular neurobiology

2024

Abstract: Defective β-catenin signaling is accompanied with compensatory neurogenesis process that may pave to anxiety. β-Catenin has a distinct role in alleviating anxiety in adolescence; however, it undergoes degradation by the degradation complex Axin and APC. ... ...

Abstract	Defective β-catenin signaling is accompanied with compensatory neurogenesis process that may pave to anxiety. β-Catenin has a distinct role in alleviating anxiety in adolescence; however, it undergoes degradation by the degradation complex Axin and APC. Vilazodone (VZ) is a fast, effective antidepressant with SSRI activity and 5-HT
Language	English
Publishing date	2024-04-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	645020-9
ISSN	1559-1182 ; 0893-7648
ISSN (online)	1559-1182
ISSN	0893-7648
DOI	10.1007/s12035-024-04142-3
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Article ; Online: Influence of β-catenin signaling on neurogenesis in neuropsychiatric disorders: Anxiety and depression.

El-Kadi, Rana A / AbdelKader, Noha F / Zaki, Hala F / Kamel, Ahmed S

Drug development research

2024 Volume 85, Issue 1, Page(s) e22157

Abstract: It has been proven that stress, mainly in the early years of life, can lead to anxiety and mood problems. Current treatments for psychiatric disorders are not enough, and some of them show intolerable side effects, emphasizing the urgent need for new ... ...

Abstract	It has been proven that stress, mainly in the early years of life, can lead to anxiety and mood problems. Current treatments for psychiatric disorders are not enough, and some of them show intolerable side effects, emphasizing the urgent need for new treatment targets. Hence, a better understanding of the different brain networks, which are involved in the response to anxiety and depression, may evoke treatments with more specific targets. One of these targets is β-catenin that regulates brain circuits. β-Catenin has a dual response toward stress, which may influence coping or vulnerability to stress response. Indeed, β-catenin signaling involves several processes such as inflammation-directed brain repair, inflammation-induced brain damage, and neurogenesis. Interestingly, β-catenin reduction is accompanied by low neurogenesis, which leads to anxiety and depression. However, in another state, this reduction activates a compensatory mechanism that enhances neurogenesis to protect against depression but may precipitate anxiety. Thus, understanding the molecular mechanism of β-catenin could enhance our knowledge about anxiety and depression's pathophysiology, potentially improving clinical results by targeting it. Herein, the different states of β-catenin were discussed, shedding light on possible drugs that showed action on psychiatric disorders through β-catenin.
MeSH term(s)	Humans ; Anxiety/drug therapy ; beta Catenin ; Depression/drug therapy ; Inflammation ; Neurogenesis
Chemical Substances	beta Catenin
Language	English
Publishing date	2024-02-13
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	604587-x
ISSN	1098-2299 ; 0272-4391
ISSN (online)	1098-2299
ISSN	0272-4391
DOI	10.1002/ddr.22157
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Article ; Online: Retraction Note to: Fetal fibronectin (Quick Check fFN test) versus placental alpha microglobulin-1 (AmniSure test) for detection of premature rupture of fetal membranes.

Abdelazim, Ibrahim A / Abdelrazak, Khaled M / Al-Kadi, Mohamed / Yehia, Amr H / Abdulkareem, Amr F

Archives of gynecology and obstetrics

2024 Volume 309, Issue 5, Page(s) 2263

Language	English
Publishing date	2024-02-20
Publishing country	Germany
Document type	Retraction of Publication
ZDB-ID	896455-5
ISSN	1432-0711 ; 0932-0067
ISSN (online)	1432-0711
ISSN	0932-0067
DOI	10.1007/s00404-024-07430-4
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Book: Adaptation of human skeletal muscle to training and anabolic steroids

Kadi, Fawzi

(Acta physiologica Scandinavica : Supplementum ; 646)

2000

Author's details	by Fawzi Kadi
Series title	Acta physiologica Scandinavica : Supplementum ; 646 Acta physiologica Scandinavica Acta physiologica Scandinavica ; Supplementum
Collection	Acta physiologica Scandinavica Acta physiologica Scandinavica ; Supplementum
Language	English
Size	52 S. : Ill., graph. Darst.
Publisher	Blackwell Science
Publishing place	Stockholm
Publishing country	Sweden
Document type	Book
HBZ-ID	HT011257437
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
Uc I Zs 229 -Suppl.646-	verfügbar in Königswinter	Königswinter

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Article: Hybrid Chitosan-TiO

Al-Kadi, Faten K / Abdulkareem, Jwan F / Azhdar, Bruska A

Nanomaterials (Basel, Switzerland)

2023 Volume 13, Issue 16

Abstract: This study explores the impact of the incorporation of a chitosan- ... ...

Abstract	This study explores the impact of the incorporation of a chitosan-TiO
Language	English
Publishing date	2023-08-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano13162379
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Article ; Online: Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults.

Papaioannou, Konstantinos-Georgios / Kadi, Fawzi / Nilsson, Andreas

Nutrients

2022 Volume 14, Issue 9

Abstract: It is hypothesized that healthy diets rich in fruits and vegetables (FV) can modulate the inflammatory status in older adults. However, to determine the actual impact of FV on inflammatory status, adiposity level and objectively assessed physical ... ...

Abstract	It is hypothesized that healthy diets rich in fruits and vegetables (FV) can modulate the inflammatory status in older adults. However, to determine the actual impact of FV on inflammatory status, adiposity level and objectively assessed physical activity (PA) behaviors need to be considered. The aim of the present study was to explore associations between FV intake and biomarkers of systemic inflammation in older adults. Based on a sample of 233 older adults (65−70 years old), the following inflammatory biomarkers were assessed: C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6), IL-10, IL-18, and monocyte chemoattractant protein-1 (MCP-1). FV intake was assessed by self-report, and PA behaviors encompassing time spent sedentary and in moderate-to-vigorous PA (MVPA) were determined using accelerometers. Associations between FV intake and inflammatory biomarkers were analyzed using stepwise linear regression models while adjusting for several covariates, including health-related food groups, adherence to the MVPA guidelines, total sedentary time, and waist circumference. While no significant associations were observed for the total FV intake, the vegetable intake was inversely associated with levels of IL6 (β = −0.15; p < 0.05). In contrast, fruit intake was not associated with any inflammatory biomarker. In conclusion, our findings indicate beneficial associations between vegetable intake and levels of a pro-inflammatory biomarker in older adults, which strengthens public health efforts to promote vegetable-rich diets in older adults to mitigate age-related systemic inflammation.
MeSH term(s)	Aged ; Biomarkers ; Diet ; Fruit ; Humans ; Inflammation ; Vegetables
Chemical Substances	Biomarkers
Language	English
Publishing date	2022-04-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu14091765
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Article ; Online: Benefits of Fruit and Vegetable Consumption on Prevalence of Metabolic Syndrome Are Independent of Physical Activity Behaviors in Older Adults.

Papaioannou, Konstantinos-Georgios / Kadi, Fawzi / Nilsson, Andreas

Nutrients

2022 Volume 14, Issue 2

Abstract: Although consumption of fruits and vegetables (FV) is suggested to reduce metabolic risk, there is a paucity of studies taking advantage of objectively assessed physical activity (PA) behaviors when exploring links between FV intake and metabolic ... ...

Abstract	Although consumption of fruits and vegetables (FV) is suggested to reduce metabolic risk, there is a paucity of studies taking advantage of objectively assessed physical activity (PA) behaviors when exploring links between FV intake and metabolic syndrome (MetS) in older adults. The aim of the present study was to determine the relationship between FV intake and MetS prevalence in a population of older community-dwelling adults, while considering time spent being sedentary and health-enhancing PA. Prevalence of MetS was determined in a population of 93 men and 152 women (age: 65-70 years). FV intake was determined by self-report and PA behaviors (time spent in moderate-to-vigorous PA (MVPA) and in sedentary) were assessed by accelerometry. Likelihood of having MetS by FV intake was determined using logistic regression with stepwise backward elimination including age, sex, educational level, total energy intake, adherence to MVPA guideline and total sedentary time as covariates. A main finding was that lower FV intakes were significantly related to higher prevalence of MetS (odds ratio [OR]: 1.23; 95% confidence interval [CI]: 1.03-1.47) after considering potential influences by covariates. Additionally, we found that lower intake of vegetables but not fruits was significantly related to higher prevalence of MetS (OR: 1.47; 95%CI: 1.04-2.07). In conclusion, lower intakes of FV in general, and of vegetables in particular, significantly increased likelihood of MetS, regardless of time spent sedentary and adherence to the MVPA guideline. From a public health perspective, our findings emphasize adequate intakes of FV as an independent contributor to metabolic health status in older adults.
MeSH term(s)	Accelerometry ; Aged ; Diet ; Exercise ; Feeding Behavior ; Female ; Fruit ; Health Behavior ; Health Status ; Humans ; Male ; Metabolic Syndrome/prevention & control ; Odds Ratio ; Physical Exertion ; Prevalence ; Risk Factors ; Sedentary Behavior ; Self Report ; Vegetables
Language	English
Publishing date	2022-01-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu14020263
Database	MEDical Literature Analysis and Retrieval System OnLINE

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