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  1. Article: Mechanistic Understanding of the Palmitoylation of G

    Zhang, Hao / Chu, Guojun / Wang, Gaoming / Yao, Min / Lu, Shaoyong / Chen, Ting

    Pharmaceutics

    2022  Volume 14, Issue 9

    Abstract: Adhesion G-protein-coupled receptors (aGPCRs)-a major family of GPCRs-play critical roles ... of the C-terminal G ...

    Abstract Adhesion G-protein-coupled receptors (aGPCRs)-a major family of GPCRs-play critical roles in the regulation of tissue development and cancer progression. The orphan receptor GPR97, activated by glucocorticoid stress hormones, is a prototypical aGPCR. Although it has been established that the palmitoylation of the C-terminal G
    Language English
    Publishing date 2022-09-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics14091856
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  2. Article ; Online: g-C

    Zhang, Yanlin / Chu, Wei

    Chemosphere

    2022  Volume 293, Page(s) 133611

    Abstract: In this study, a ... ...

    Abstract In this study, a Fe
    MeSH term(s) Acceleration ; Light ; Metronidazole ; Peroxides
    Chemical Substances Peroxides ; Metronidazole (140QMO216E) ; peroxymonosulfate (22047-43-4)
    Language English
    Publishing date 2022-01-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.133611
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
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  3. Article ; Online: Removal of sulfonylurea herbicides with g-C

    Liu, Bingkun / Tian, Weijun / Chu, Meile / Lu, Zhiyang / Zou, Mengyuan / Chen, Zhuo / Zhang, Ruijuan

    Chemosphere

    2024  Volume 354, Page(s) 141742

    Abstract: ... nitride (g-C ...

    Abstract The accumulation of agricultural chemicals in the environment has become a global concern, of which sulfonylurea herbicides (SUHs) constitute a significant category. Solar-driven photocatalysis is favored for removing organic pollutants due to its high efficiency and environmental friendliness. Graphite carbon nitride (g-C
    MeSH term(s) Catalysis ; Environmental Pollutants
    Chemical Substances Environmental Pollutants
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141742
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  4. Article ; Online: The μ-opioid receptor-mediated G

    Xia, Jing / Li, Xiaoyan / Zhu, Hongyu / Zhou, Xiaohui / Chen, Ji / Li, Qihong / Li, Shupeng / Chu, Haichen / Dong, Mingxin

    European journal of pharmacology

    2024  Volume 966, Page(s) 176333

    Abstract: The μ-opioid receptor-biased agonist theory holds that G ...

    Abstract The μ-opioid receptor-biased agonist theory holds that G
    MeSH term(s) Mice ; Animals ; Morphine/adverse effects ; Analgesics, Opioid/adverse effects ; Analgesics, Opioid/metabolism ; Receptors, Opioid, mu/metabolism ; Signal Transduction ; Constipation/chemically induced ; Peptides/metabolism ; beta-Arrestin 2/metabolism
    Chemical Substances Morphine (76I7G6D29C) ; Analgesics, Opioid ; Receptors, Opioid, mu ; Peptides ; beta-Arrestin 2
    Language English
    Publishing date 2024-01-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 80121-5
    ISSN 1879-0712 ; 0014-2999
    ISSN (online) 1879-0712
    ISSN 0014-2999
    DOI 10.1016/j.ejphar.2024.176333
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    Zs.A 522: Show issues Location:
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  5. Article ; Online: Controlled synthesis of 2D-2D conductive metal-organic framework/g-C

    Chu, Xiaoyu / Luan, Bing-Bing / Huang, Ao-Xiang / Zhao, Yongkuo / Guo, Hongxia / Ning, Yang / Cheng, Haojian / Zhang, Guiling / Zhang, Feng-Ming

    Dalton transactions (Cambridge, England : 2003)

    2024  Volume 53, Issue 6, Page(s) 2534–2540

    Abstract: ... organic framework/g-C ...

    Abstract Designing photocatalysts with efficient charge separation and electron transport capabilities to achieve efficient visible-driven hydrogen production remains a challenge. Herein, 2D-2D conductive metal-organic framework/g-C
    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt03894g
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  6. Article ; Online: Structures of G

    Lin, Shuling / Han, Shuo / Cai, Xiaoqing / Tan, Qiuxiang / Zhou, Kexiu / Wang, Dejian / Wang, Xinwei / Du, Juan / Yi, Cuiying / Chu, Xiaojing / Dai, Antao / Zhou, Yan / Chen, Yan / Zhou, Yu / Liu, Hong / Liu, Jianfeng / Yang, Dehua / Wang, Ming-Wei / Zhao, Qiang /
    Wu, Beili

    Nature

    2021  Volume 594, Issue 7864, Page(s) 583–588

    Abstract: The metabotropic glutamate receptors (mGlus) have key roles in modulating cell excitability and synaptic transmission in response to glutamate (the main excitatory neurotransmitter in the central nervous system) ...

    Abstract The metabotropic glutamate receptors (mGlus) have key roles in modulating cell excitability and synaptic transmission in response to glutamate (the main excitatory neurotransmitter in the central nervous system)
    MeSH term(s) Binding Sites ; Cryoelectron Microscopy ; GTP-Binding Proteins/chemistry ; Humans ; Protein Multimerization ; Protein Structure, Tertiary ; Receptors, Metabotropic Glutamate/chemistry ; Signal Transduction
    Chemical Substances Receptors, Metabotropic Glutamate ; metabotropic glutamate receptor 2 ; GTP-Binding Proteins (EC 3.6.1.-) ; metabotropic glutamate receptor 4 (YZN9W7P1BX)
    Language English
    Publishing date 2021-06-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-021-03495-2
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    Zs.MO 244: Show issues

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  7. Article ; Online: Inhibition mechanism of fusarium graminearum growth by g-C

    Chen, Xingguang / Gu, Qianhui / Chu, Beibei / Zhang, Yongxin / Chen, Ziqiang / Ma, Mingtao / Li, Dingding / Lu, Jian / Wu, Dianhui

    International journal of food microbiology

    2024  Volume 413, Page(s) 110578

    Abstract: ... growth by g-C ...

    Abstract The increase of deoxynivalenol (DON) caused by Fusarium graminearum (F. graminearum) during the malting process is a serious safety problem. In our work, the inhibition mechanism of F. graminearum growth by g-C
    MeSH term(s) Mycotoxins/analysis ; Trichothecenes/analysis ; Food Microbiology ; Hordeum/microbiology ; Fusarium/metabolism
    Chemical Substances Mycotoxins ; Trichothecenes
    Language English
    Publishing date 2024-01-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 87122-9
    ISSN 1879-3460 ; 0168-1605
    ISSN (online) 1879-3460
    ISSN 0168-1605
    DOI 10.1016/j.ijfoodmicro.2024.110578
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  8. Article ; Online: Enhancement of the Peroxidase Activity of g-C

    Che, Huachao / Tian, Xike / Guo, Fei / Nie, Yulun / Dai, Chu / Li, Yong / Lu, Liqiang

    Analytical chemistry

    2023  Volume 95, Issue 33, Page(s) 12550–12556

    Abstract: ... highly anticipated. In this study, different morphologies of g-C ...

    Abstract The classes and forms of antibiotics directly determine their ecotoxicity and environmental chemical behavior, and developing a sensor array for simultaneous and in situ detection of antibiotics is highly anticipated. In this study, different morphologies of g-C
    MeSH term(s) Anti-Bacterial Agents ; Reproducibility of Results ; Metal-Organic Frameworks/chemistry ; Peroxidases
    Chemical Substances Anti-Bacterial Agents ; MIL-101 ; Metal-Organic Frameworks ; Peroxidases (EC 1.11.1.-)
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c02911
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  9. Article: Stimulatory G-Protein

    He, Lifan / Lu, Hanlin / Ji, Xuyang / Chu, Jianying / Qin, Xiaoteng / Chen, Min / Weinstein, Lee S / Gao, Jiangang / Yang, Jianmin / Zhang, Qunye / Zhang, Cheng / Zhang, Wencheng

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 941064

    Abstract: ... subunit of the heterotrimeric G-stimulatory protein (Gsα) mediates receptor-stimulated production ...

    Abstract Endothelial cell leakage occurs in several diseases. Intracellular junctions and transcellular fashion are involved. The definite regulatory mechanism is complicated and not fully elucidated. The alpha subunit of the heterotrimeric G-stimulatory protein (Gsα) mediates receptor-stimulated production of cyclic adenosine monophosphate (cAMP). However, the role of Gsα in the endothelial barrier remains unclear. In this study, mice with knockout of endothelial-specific Gsα (Gsα
    Language English
    Publishing date 2022-06-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.941064
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  10. Article ; Online: The nematode-trapping fungus Arthrobotrys oligospora detects prey pheromones via G protein-coupled receptors.

    Kuo, Chih-Yen / Tay, Rebecca J / Lin, Hung-Che / Juan, Sheng-Chian / Vidal-Diez de Ulzurrun, Guillermo / Chang, Yu-Chu / Hoki, Jason / Schroeder, Frank C / Hsueh, Yen-Ping

    Nature microbiology

    2024  

    Abstract: ... families of G protein-coupled receptors (GPCRs) involved in sensing distinct nematode-derived cues. GPCRs ...

    Abstract The ability to sense prey-derived cues is essential for predatory lifestyles. Under low-nutrient conditions, Arthrobotrys oligospora and other nematode-trapping fungi develop dedicated structures for nematode capture when exposed to nematode-derived cues, including a conserved family of pheromones, the ascarosides. A. oligospora senses ascarosides via conserved MAPK and cAMP-PKA pathways; however, the upstream receptors remain unknown. Here, using genomic, transcriptomic and functional analyses, we identified two families of G protein-coupled receptors (GPCRs) involved in sensing distinct nematode-derived cues. GPCRs homologous to yeast glucose receptors are required for ascaroside sensing, whereas Pth11-like GPCRs contribute to ascaroside-independent nematode sensing. Both GPCR classes activate conserved cAMP-PKA signalling to trigger trap development. This work demonstrates that predatory fungi use multiple GPCRs to sense several distinct nematode-derived cues for prey recognition and to enable a switch to a predatory lifestyle. Identification of these receptors reveals the molecular mechanisms of cross-kingdom communication via conserved pheromones also sensed by plants and animals.
    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ISSN 2058-5276
    ISSN (online) 2058-5276
    DOI 10.1038/s41564-024-01679-w
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