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  1. Article ; Online: A

    Aguirre-Chen, Cristina / Stec, Natalia / Ramos, Olivia Mendivil / Kim, Nuri / Kramer, Melissa / McCarthy, Shane / Gillis, Jesse / McCombie, W Richard / Hammell, Christopher M

    G3 (Bethesda, Md.)

    2020  Volume 10, Issue 5, Page(s) 1617–1628

    Abstract: Analysis of patient-derived DNA samples has identified hundreds of variants that are likely involved in neuropsychiatric diseases such as autism spectrum disorder (ASD) and schizophrenia (SCZ). While these studies couple behavioral phenotypes to ... ...

    Abstract Analysis of patient-derived DNA samples has identified hundreds of variants that are likely involved in neuropsychiatric diseases such as autism spectrum disorder (ASD) and schizophrenia (SCZ). While these studies couple behavioral phenotypes to individual genotypes, the number and diversity of candidate genes implicated in these disorders highlights the fact that the mechanistic underpinnings of these disorders are largely unknown. Here, we describe a RNAi-based screening platform that uses
    MeSH term(s) Animals ; Autism Spectrum Disorder/genetics ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Humans ; RNA Interference ; Transcription Factors/genetics
    Chemical Substances Caenorhabditis elegans Proteins ; Transcription Factors
    Language English
    Publishing date 2020-05-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2629978-1
    ISSN 2160-1836 ; 2160-1836
    ISSN (online) 2160-1836
    ISSN 2160-1836
    DOI 10.1534/g3.119.400925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Monitoring der Immunrekonstitution mittels TREC und KREC nach allogener Stammzelltransplantation

    Krämer, Aurelia

    2022  

    Author's details vorgelegt 2022 von Aurelia Krämer
    Language German
    Size III, 95 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Freiburg im Breisgau
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Albert-Ludwigs-Universität Freiburg im Breisgau, 2022
    HBZ-ID HT030638960
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2024 E 269 order for loan Magazin

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  3. Book ; Online ; E-Book: Geschlecht als Zäsur

    Krämer, Anike

    Zum Alltagserleben von Eltern intergeschlechtlicher Kinder

    (Wissen, Kommunikation und Gesellschaft, Schriften zur Wissenssoziologie,)

    2021  

    Abstract: Eine Inter*-Diagnose stellt für die meisten Eltern eine Zäsur im Leben dar. Die gesellschaftliche und körperliche Bedeutung ist nicht in ihrem Erfahrungswissen verankert. Dieses Buch geht dem Erleben der Eltern von intergeschlechtlichen Kindern nach und ... ...

    Author's details von Anike Krämer
    Series title Wissen, Kommunikation und Gesellschaft, Schriften zur Wissenssoziologie,
    Abstract Eine Inter*-Diagnose stellt für die meisten Eltern eine Zäsur im Leben dar. Die gesellschaftliche und körperliche Bedeutung ist nicht in ihrem Erfahrungswissen verankert. Dieses Buch geht dem Erleben der Eltern von intergeschlechtlichen Kindern nach und zeichnet deren Prozess der Auseinandersetzung, Wissensaneignung und Handlungsermächtigung nach. Überlegungen zur Naturalisierung von Geschlecht und zur Wirklichkeitskrise sind dabei zentral. Die Autorin verknüpft zudem das Erleben mit den aktuellen gesellschaftlichen Verhältnissen und bietet so Erkenntnisse zur Krisenbewältigung an. Die Autorin Anike Krämer Sozialwissenschaftlerin, forscht und lehrt insbesondere zu den Verhältnissen von Normalisierung, Naturalisierung, Geschlecht, Wissen und Gesellschaft. Derzeit arbeitet sie am Zentrum für Geschlechterstudien/Gender Studies der Universität Paderborn.
    Keywords Health ; Sex. ; Social medicine ; Human body/Social aspects ; Expertise ; Gender and Health ; Health, Medicine and Society ; Sociology of the Body ; Expertise Studies
    Subject code 613.04
    Language German
    Size 1 online resource (236 pages)
    Edition 1st ed. 2021.
    Publisher Springer Fachmedien Wiesbaden ; Imprint: Springer VS
    Publishing place Wiesbaden
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-658-34142-4 ; 3-658-34141-6 ; 978-3-658-34142-8 ; 978-3-658-34141-1
    DOI 10.1007/978-3-658-34142-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online ; E-Book: Covid-19 pandisziplinär und international

    Krämer, Alexander / Medzech, Michael

    gesundheitswissenschaftliche, gesellschaftspolitische und philosophische Hintergründe

    (Medizin, Kultur, Gesellschaft)

    2023  

    Author's details Alexander Krämer, Michael Medzech (Hrsg.)
    Series title Medizin, Kultur, Gesellschaft
    Keywords Communication in medicine ; Public health
    Language German
    Size 1 Online-Ressource (XIII, 555 Seiten), Illustrationen, Diagramme
    Publisher Springer VS
    Publishing place Wiesbaden
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030620518
    ISBN 978-3-658-40525-0 ; 9783658405243 ; 3-658-40525-2 ; 3658405244
    DOI 10.1007/978-3-658-40525-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book ; Online: Katechismus landwirthschaftlicher Verhältnisse

    Krämer, A.

    zum Gebrauch für den Ackerbauschüler

    (Digitale Sammlungen der ZB MED - Informationszentrum Lebenswissenschaften)

    2019  

    Title variant Katechismus landwirtschaftlicher Verhältnisse
    Author's details entworfen von Dr. A. Krämer
    Series title Digitale Sammlungen der ZB MED - Informationszentrum Lebenswissenschaften
    Language German
    Size 1 Online-Ressource (37 Seiten)
    Publisher ZB MED - Informationszentrum Lebenswissenschaften
    Publishing place Köln
    Publishing country XA-DXDE
    Document type Book ; Online
    HBZ-ID CT002015981
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Book ; Thesis: The prognostic and therapeutic relevance of TERT activation in neuroblastoma

    Krämer, Andrea

    2017  

    Author's details vorgelegt von Andrea Krämer aus Bergisch Gladbach
    Language English
    Size iii, IV, 92 Seiten, Illustrationen, Diagramme
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität zu Köln, 2017
    Note Zusammenfassung in deutscher und englischer Sprache
    HBZ-ID HT019502436
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 D 1124 order for loan Magazin

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  7. Article: The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels

    Krämer, Andreas

    Scientific reports, 7:41248

    2017  

    Abstract: Rer1 is a sorting receptor in the early secretory pathway that controls the assembly and the cell surface transport of selected multimeric membrane protein complexes. Mice with a Purkinje cell (PC) specific deletion of Rer1 showed normal polarization and ...

    Institution Leibniz-Institut für Alternsforschung
    Abstract Rer1 is a sorting receptor in the early secretory pathway that controls the assembly and the cell surface transport of selected multimeric membrane protein complexes. Mice with a Purkinje cell (PC) specific deletion of Rer1 showed normal polarization and differentiation of PCs and normal development of the cerebellum. However, PC-specific loss of Rer1 led to age-dependent motor deficits in beam walk, ladder climbing and gait. Analysis of brain sections revealed a specific degeneration of PCs in the anterior cerebellar lobe in old animals. Electrophysiological recordings demonstrated severe deficits in spontaneous action potential generation. Measurements of resurgent currents indicated decreased surface densities of voltage-gated sodium channels (Nav), but not changes in individual channels. Analysis of mice with a whole brain Rer1-deletion demonstrated a strong down-regulation of Nav1.6 and 1.1 in the absence of Rer1, whereas protein levels of the related Cav2.1 and of Kv3.3 and 7.2 channels were not affected. The data suggest that Rer1 controls the assembly and transport of Nav1.1 and 1.6, the principal sodium channels responsible for recurrent firing, in PCs.
    Keywords Cellular neuroscience ; Endoplasmic reticulum
    Language English
    Document type Article
    Database Repository for Life Sciences

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  8. Book ; Online ; E-Book: Flucht und Gesundheit

    Nowak, Anna Christina / Krämer, Alexander / Schmidt, Kerstin

    Facetten eines interdisziplinären Zugangs

    (Z'Flucht. Sonderband ; 1)

    2021  

    Author's details Anna Christina Nowak, Alexander Krämer, Kerstin Schmidt (Hrsg.)
    Series title Z'Flucht. Sonderband ; 1
    Z'Flucht
    Collection Z'Flucht
    Keywords Flucht ; Migrationshintergrund
    Subject Zuwanderungshintergrund ; Entweichen ; Entfliehen
    Language German
    Size 1 Online-Ressource (240 Seiten), Illustrationen
    Edition 1. Auflage
    Publisher Nomos
    Publishing place Baden-Baden
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021769708
    ISBN 978-3-7489-0645-2 ; 9783848765034 ; 3-7489-0645-5 ; 3848765039
    DOI 10.5771/9783748906452
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  9. Book ; Online: Die landwirthschaftliche Schule des Eidgenössischen Polytechnikums in Zürich

    Kraemer, Adolf

    Festschrift zur Feier ihres 25jährigen Bestehens am Schlusse des Schuljahres 1895/96

    (Digitale Sammlungen der ZB MED - Informationszentrum Lebenswissenschaften)

    2019  

    Title variant Die landwirtschaftliche Schule des Eidgenössischen Polytechnikums in Zürich
    Institution Landwirthschaftliche Schule
    Author's details im Auftrage des Schweizer. Schulrathes verfasst von Dr. Adolf Kraemer, Professor der Landwirthschaft am eidgen. Polytechnikum in Zürich
    Series title Digitale Sammlungen der ZB MED - Informationszentrum Lebenswissenschaften
    Keywords Schweiz ; Landwirtschaft ; Einrichtung
    Subject Institution ; Agrarwirtschaft ; Agrarsektor ; Landwirtschaftlicher Sektor
    Language German
    Size 1 Online-Ressource (VI, 168 Seiten, 10 ungezählte Blätter Tafeln), Illustrationen
    Publisher ZB MED - Informationszentrum Lebenswissenschaften
    Publishing place Köln
    Publishing country Switzerland
    Document type Book ; Online
    HBZ-ID CT002016457
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Book ; Thesis: The role of human Slfn5 and its Xenopus Laevis ortholog in mitotic cell cycle progression and oocyte meiotic resumption

    Vit, Gianmatteo / Krämer, Alwin

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Gianmatteo Vit ; Doktorvater: Herr Prof. Dr. med. Alwin Krämer
    Language English
    Size III, 127 Seiten, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    HBZ-ID HT020933597
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 E 665 order for loan Magazin

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