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  1. Article: Editorial: Multi-omics analysis in tumor microenvironment and tumor heterogeneity.

    Shi, Yuxin / Zhang, Qinglin / Mei, Jie / Liu, Jinhui

    Frontiers in genetics

    2023  Volume 14, Page(s) 1271295

    Language English
    Publishing date 2023-08-23
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1271295
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  2. Article ; Online: Root damage of street trees in urban environments: An overview of its hazards, causes, and prevention and control measures.

    Shi, Feng / Meng, Qinglin / Pan, Lan / Wang, Junsong

    The Science of the total environment

    2023  Volume 904, Page(s) 166728

    Abstract: Root damage from urban street trees represents a substantial concern arising from the conflict between root growth and limited growth spaces. Nonetheless, the phenomenon of root damage, which threatens the safety of urban facilities, appears to have ... ...

    Abstract Root damage from urban street trees represents a substantial concern arising from the conflict between root growth and limited growth spaces. Nonetheless, the phenomenon of root damage, which threatens the safety of urban facilities, appears to have received little scholarly attention. Moreover, the effectiveness of some proposed measures for root damage prevention and control has not yet received consistent evaluation. Accordingly, this review aims to examine root damage, including its causes and available prevention and control measures. Urban trees are found to have a high potential to exert root damage on infrastructures when the following factors exist. These include large and mature tree, fast-growing trees, trees planted in limited soil volumes, shallow-rooted tree with buttress roots, trees whose diameter at breast height exceeds 10 cm, old and cracked road paving, high soil surface moisture content, short distances between trees and sidewalks (<2 to 3 m), and underground pipes that are already broken and made of metals or stones. The phenotypic traits of trees may be the primary factor causing root damage when there is a mismatch between the root-soil requirements of urban street trees and the actual soil environment. The poor effectiveness of root damage prevention and control measures may be attributed to the lack of connection between the development of control measures and the mechanism of root damage.
    MeSH term(s) Trees ; Soil/chemistry
    Chemical Substances Soil
    Language English
    Publishing date 2023-09-02
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.166728
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
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  3. Article ; Online: Epigenome-wide association study on ambient PM

    Cai, Xiyang / Song, Qinglin / Meng, Xia / Li, Kaixuan / Shi, Su / Jin, Li / Kan, Haidong / Wang, Sijia

    Environmental research

    2024  Volume 247, Page(s) 118276

    Abstract: ... Ambient ... ...

    Abstract Ambient PM
    MeSH term(s) Humans ; Air Pollutants/toxicity ; Air Pollutants/analysis ; Particulate Matter/toxicity ; Particulate Matter/analysis ; Epigenome ; DNA Methylation ; China
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2024-01-19
    Publishing country Netherlands
    Document type Systematic Review ; Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2024.118276
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
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  4. Article ; Online: Defect-engineering improves the activity of Metal-Organic frameworks for catalyzing hydroboration of Alkynes: A combination of experimental investigation and Density functional theory calculations.

    Tian, Long / Song, Xiaonan / Liu, Yi / Zhang, Churu / Shi, Lan / Chen, Qinglin / Deng, Yanyan / Cui, Weigang / Shan, Shaoyun / Hu, Tianding

    Journal of colloid and interface science

    2024  Volume 662, Page(s) 263–275

    Abstract: Defect-engineered metal-organic frameworks (DEMOFs) are emerging advanced materials. The construction of DEMOFs is of great significance; however, DEMOF-based catalysis remains unexplored. (E)-vinylboronates, an important building block for asymmetric ... ...

    Abstract Defect-engineered metal-organic frameworks (DEMOFs) are emerging advanced materials. The construction of DEMOFs is of great significance; however, DEMOF-based catalysis remains unexplored. (E)-vinylboronates, an important building block for asymmetric synthesis, can be synthesized via the hydroboration of alkynes. However, the lack of high-performance catalysts considerably hinders their synthesis. Herein, a series of DEHKUST-1 (HKUST = Hong Kong University of Science and Technology) (Da-f) catalysts with missing occupation of linkers at Cu nodes were designed by partially replacing benzene-1,3,5-tricarboxylate (H
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2024.02.067
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    In stock of ZB MED Bonn / Germany

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  5. Article ; Online: Experiences and perspectives of nurses infected with COVID-19: A qualitative systematic review and meta-synthesis.

    Yao, Yue / Zeng, Qinglin / Wang, Yuqiang / Shi, Huijing / Zeng, Yanli

    Nursing & health sciences

    2023  Volume 25, Issue 4, Page(s) 530–542

    Abstract: This qualitative systematic review aims to comprehensively understand the experiences and perspectives of nurses infected with COVID-19, addressing a significant gap in the current literature. Following the JBI meta-synthesis approach, a rigorous search ... ...

    Abstract This qualitative systematic review aims to comprehensively understand the experiences and perspectives of nurses infected with COVID-19, addressing a significant gap in the current literature. Following the JBI meta-synthesis approach, a rigorous search was conducted across nine electronic databases and references until January 16, 2023. Seventeen eligible studies underwent quality assessment using the JBI critical checklist. Data were synthesized using standardized tools, and the ConQual tool evaluated confidence in the findings. Seven key findings emerged, providing valuable insights into emotional experiences, adaptation to COVID-19 challenges, influence of support systems, coping strategies, posttraumatic growth perceptions, and effects on professional identity and career advancement. The findings highlight emotional toll, adaptive strategies, and professional implications for nurses. Moreover, they emphasize the importance of support systems, coping mechanisms, and posttraumatic growth in promoting nurses' well-being and resilience. These insights have practical implications for targeted interventions and support mechanisms to enhance infected nurses' well-being and improve healthcare outcomes.
    MeSH term(s) Humans ; Qualitative Research ; COVID-19 ; Resilience, Psychological ; Nurse's Role/psychology
    Language English
    Publishing date 2023-11-08
    Publishing country Australia
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2213282-X
    ISSN 1442-2018 ; 1441-0745
    ISSN (online) 1442-2018
    ISSN 1441-0745
    DOI 10.1111/nhs.13065
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6245: Show issues Location:
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  6. Article ; Online: Mesoporous Graphitic Carbon Nitride Photocatalyzed Switchable Divergent Perfluoroalkylation of Terminal Alkynes.

    Shi, Xiaolin / Song, Tao / Li, Qinglin / Guo, Xiuling / Yang, Yong

    Organic letters

    2022  Volume 24, Issue 47, Page(s) 8724–8728

    Abstract: An efficient and eco-friendly heterogeneous photocatalytic system for the switchable divergent perfluoroalkylation of terminal alkynes has been developed by employing mesoporous graphitic carbon nitride (mpg-CN) as a recyclable, nontoxic, and heavy-metal- ...

    Abstract An efficient and eco-friendly heterogeneous photocatalytic system for the switchable divergent perfluoroalkylation of terminal alkynes has been developed by employing mesoporous graphitic carbon nitride (mpg-CN) as a recyclable, nontoxic, and heavy-metal-free photocatalyst. Regulating the reaction solvents allowed libraries of perfluoroalkylated alkynes, alkenes, and alkenyl iodides to be synthesized in good-to-high yields. Furthermore, mpg-CN is applicable for gram-scale photosynthesis and could be readily recovered for successive reuses.
    Language English
    Publishing date 2022-11-20
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.2c03814
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  7. Article ; Online: Suppression of pancreatic cancer proliferation through TXNIP-mediated inhibition of the MAPK signaling pathway.

    Fei, Qinglin / Jin, Kaizhou / Shi, Saimeng / Li, Tianjiao / Guo, Duancheng / Lin, Mengxiong / Yu, Xianjun / Wu, Weiding / Ye, Longyun

    Acta biochimica et biophysica Sinica

    2024  Volume 56, Issue 4, Page(s) 513–524

    Abstract: Thioredoxin-interacting protein (TXNIP) is a crucial thioredoxin-binding protein that is recognized as a tumor suppressor in diverse malignancies, such as breast cancer, lung cancer, hepatocellular carcinoma, and thyroid cancer. However, the specific ... ...

    Abstract Thioredoxin-interacting protein (TXNIP) is a crucial thioredoxin-binding protein that is recognized as a tumor suppressor in diverse malignancies, such as breast cancer, lung cancer, hepatocellular carcinoma, and thyroid cancer. However, the specific role and molecular mechanisms of TXNIP in the pathogenesis and progression of pancreatic cancer cells have not been determined. In this study, we investigate the relationship between TXNIP expression and overall survival prognosis in pancreatic cancer patients. Mechanistic studies are conducted to reveal the role of TXNIP in pancreatic cancer cell proliferation, migration, and regulation during malignancy. Our findings indicate that patients with high TXNIP expression have a more favorable prognosis.
    MeSH term(s) Humans ; Cell Line, Tumor ; Pancreatic Neoplasms/metabolism ; Signal Transduction ; Thioredoxins/genetics ; Thioredoxins/metabolism ; Liver Neoplasms/pathology ; Cell Proliferation ; Carrier Proteins/genetics ; Carrier Proteins/metabolism
    Chemical Substances Thioredoxins (52500-60-4) ; TXNIP protein, human ; Carrier Proteins
    Language English
    Publishing date 2024-01-16
    Publishing country China
    Document type Journal Article
    ZDB-ID 2175256-4
    ISSN 1745-7270 ; 0582-9879 ; 1672-9145
    ISSN (online) 1745-7270
    ISSN 0582-9879 ; 1672-9145
    DOI 10.3724/abbs.2023286
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  8. Article ; Online: Inhibition of USP14 suppresses ferroptosis and inflammation in LPS-induced goat mammary epithelial cells through ubiquitylating the IL-6 protein.

    Zhu, Guangqin / Sui, Shaopu / Shi, Fengyun / Wang, Qinglin

    Hereditas

    2022  Volume 159, Issue 1, Page(s) 21

    Abstract: Background: Ferroptosis, a novel manner of cell death depended on iron ion, contributed to goat mammary epithelial cell dysfunction. Interleukin-6 (IL-6) is a major pro-inflammatory factor during many inflammation-related diseases including mastitis, ... ...

    Abstract Background: Ferroptosis, a novel manner of cell death depended on iron ion, contributed to goat mammary epithelial cell dysfunction. Interleukin-6 (IL-6) is a major pro-inflammatory factor during many inflammation-related diseases including mastitis, and a quite recently identified ferroptosis inducer. This study aims to explore the role of IL-6 in the dysfunction of goat mammary epithelial cells (GMECs) and how the level of IL-6 was regulated.
    Methods: Primary GMECs were isolated, cultured and treated with lipopolysaccharide (LPS) alone or together with Ferrostatin-1 (Fer-1), a well-known ferroptosis inhibitor. CCK-8 was used to detect cell viability, ELISA was used to detect TNF-α content, and the levels of ROS, GSH and MDA were analyzed with DCFDA-cell ROS detection kit, GSH assay kit and MDA assay kit, respectively. The iron ion level was measured with an iron assay kit.
    Results: The expression level of IL-6 protein in GMECs was up-regulated in response to LPS treatment, and the secretion of TNF-α, the cell oxidative stress level and the Fe
    Conclusion: IL-6 protein is deubiquitinated by USP14 and upregulated in LPS-treated GMECs, further promoting ferroptosis and inflammation through the NRF2 signaling pathway.
    MeSH term(s) Animals ; Epithelial Cells/metabolism ; Female ; Ferroptosis ; Goats/metabolism ; Inflammation/genetics ; Inflammation/metabolism ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Iron/metabolism ; Lipopolysaccharides/metabolism ; Lipopolysaccharides/pharmacology ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; RNA, Small Interfering ; Reactive Oxygen Species/metabolism ; Tumor Necrosis Factor-alpha/metabolism
    Chemical Substances Interleukin-6 ; Lipopolysaccharides ; NF-E2-Related Factor 2 ; RNA, Small Interfering ; Reactive Oxygen Species ; Tumor Necrosis Factor-alpha ; Iron (E1UOL152H7)
    Language English
    Publishing date 2022-05-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 214294-6
    ISSN 1601-5223 ; 0018-0661
    ISSN (online) 1601-5223
    ISSN 0018-0661
    DOI 10.1186/s41065-022-00235-y
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    In stock of ZB MED Cologne/Königswinter

    Ub I Zs.89: Show issues Location:
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  9. Article ; Online: The trends of burnout among health professionals during the pandemic: Three-wave cross-sectional study.

    Qin, Zhengshan / He, Zhehao / Yang, Qinglin / Meng, Zeyu / Lei, Qiuhui / Wen, Jing / Shi, Xiuquan / Liu, Jun / Wang, Zhizhong

    Asian journal of psychiatry

    2023  Volume 81, Page(s) 103458

    MeSH term(s) Humans ; Cross-Sectional Studies ; Pandemics ; Burnout, Professional ; Burnout, Psychological ; Health Personnel ; Surveys and Questionnaires
    Language English
    Publishing date 2023-01-11
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2023.103458
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  10. Article ; Online: tRF-29-79 regulates lung adenocarcinoma progression through mediating glutamine transporter SLC1A5.

    Shi, Yuanjian / Pan, Zehao / Feng, Yipeng / Zhou, Qinyao / Wang, Qinglin / Wang, Hui / Dong, Gaochao / Xia, Wenjie / Jiang, Feng

    Carcinogenesis

    2024  

    Abstract: In recent decades, considerable evidence has emerged indicating the involvement of tRNA-derived fragments (tRFs) in cancer progression through various mechanisms. However, the biological effects and mechanisms of tRFs in lung adenocarcinoma (LUAD) remain ...

    Abstract In recent decades, considerable evidence has emerged indicating the involvement of tRNA-derived fragments (tRFs) in cancer progression through various mechanisms. However, the biological effects and mechanisms of tRFs in lung adenocarcinoma (LUAD) remain unclear. In this study, we screen out tRF-29-79, a 5'-tRF derived from tRNAGlyGCC, through profiling the tRF expressions in three pairs of LUAD tissues. We show that tRF-29-79 is down-regulated in LUAD and down-regulation of tRF-29-79 is associated with poorer prognosis. In vivo and in vitro assay reveal that tRF-29-79 inhibits proliferation, migration, and invasion of LUAD cells. Mechanistically, we discovered that tRF-29-79 interacts with the RNA-binding protein PTBP1 and facilitates the transportation of PTBP1 from nucleus to cytoplasm, which regulates alternative splicing in the 3' untranslated region (UTR) of SLC1A5 pre-mRNA. Given that SLC1A5 is a core transporter of glutamine, we proved that tRF-29-79 mediate glutamine metabolism of LUAD through affecting the stability of SLC1A5 mRNA, thus exerts its anticancer function. In summary, our findings uncover the novel mechanism that tRF-29-79 participates in glutamine metabolism through interacting with PTBP1 and regulating alternative splicing in the 3' UTR of SLC1A5 pre-mRNA.
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 603134-1
    ISSN 1460-2180 ; 0143-3334
    ISSN (online) 1460-2180
    ISSN 0143-3334
    DOI 10.1093/carcin/bgae010
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1558: Show issues Location:
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