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  1. Article ; Online: Diversity and ecotones in a model ecosystems of sessile species.

    Hofer, Markus / Sneppen, Kim

    Physical review. E

    2024  Volume 109, Issue 2-1, Page(s) 24309

    Abstract: Sessile species compete for space and accessible light, with directed interactions evident in one species overgrowing another and with multispecies systems characterized by nontransitive relationships. Such patterns are observed in coral reefs or lichens ...

    Abstract Sessile species compete for space and accessible light, with directed interactions evident in one species overgrowing another and with multispecies systems characterized by nontransitive relationships. Such patterns are observed in coral reefs or lichens on rock surfaces. Open systems with episodic invasions of such species have been predicted to exhibit a stable high-diversity state when the interaction probability is below a certain critical threshold. Here, we explore this metastable high-diversity state and find that the diversity in the high-diversity state scales with the square root of the system area. When introducing two different environments, we predict a hugely increased diversity along mutual environment border. Further, the presence of spatially segregated environments is predicted to allow for increased robustness of the high-diversity state.
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.109.024309
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Breaking down the cellular responses to type I interferon neurotoxicity in the brain.

    Viengkhou, Barney / Hofer, Markus J

    Frontiers in immunology

    2023  Volume 14, Page(s) 1110593

    Abstract: Since their original discovery, type I interferons (IFN-Is) have been closely associated with antiviral immune responses. However, their biological functions go far beyond this role, with balanced IFN-I activity being critical to maintain cellular and ... ...

    Abstract Since their original discovery, type I interferons (IFN-Is) have been closely associated with antiviral immune responses. However, their biological functions go far beyond this role, with balanced IFN-I activity being critical to maintain cellular and tissue homeostasis. Recent findings have uncovered a darker side of IFN-Is whereby chronically elevated levels induce devastating neuroinflammatory and neurodegenerative pathologies. The underlying causes of these 'interferonopathies' are diverse and include monogenetic syndromes, autoimmune disorders, as well as chronic infections. The prominent involvement of the CNS in these disorders indicates a particular susceptibility of brain cells to IFN-I toxicity. Here we will discuss the current knowledge of how IFN-Is mediate neurotoxicity in the brain by analyzing the cell-type specific responses to IFN-Is in the CNS, and secondly, by exploring the spectrum of neurological disorders arising from increased IFN-Is. Understanding the nature of IFN-I neurotoxicity is a crucial and fundamental step towards development of new therapeutic strategies for interferonopathies.
    MeSH term(s) Humans ; Interferon Type I/metabolism ; Nervous System Diseases ; Brain/metabolism ; Autoimmune Diseases ; Microglia/metabolism ; Neurotoxicity Syndromes
    Chemical Substances Interferon Type I
    Language English
    Publishing date 2023-02-03
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1110593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Bakteriologische Untersuchung von Schlachttierkörpern zur Verifizierung der "In-Prozess-Kontrolle" in Schlachtbetrieben

    Hofer, Markus

    1999  

    Author's details von Markus Hofer
    Language German
    Size 64 S. : Ill., graph. Darst.
    Publishing country Switzerland
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zürich, Univ., Diss., 1999
    HBZ-ID HT012763722
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  4. Book ; Thesis: Doppler-Sonographie der testikulären Blutgefäße bei Rezidivleistenhernien

    Höfer, Karl-Markus

    1996  

    Author's details vorgelegt von Karl-Markus Höfer
    Language German
    Size 65 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Aachen, Techn. Hochsch., Diss., 1996
    HBZ-ID HT007171851
    Database Catalogue ZB MED Medicine, Health

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  5. Book ; Thesis: In-vitro- und tierexperimentelle Untersuchungen zur endoskopischen intrakorporalen Laserlithotripsie von Speichelsteinen

    Hofer, Markus

    1995  

    Author's details vorgelegt von Markus Hofer
    Language German
    Size 88 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Erlangen-Nürnberg, Univ., Diss., 1995
    Note Mikrofiche-Ausg.: 1 Mikrofiche : 24x
    HBZ-ID HT007258062
    Database Catalogue ZB MED Medicine, Health

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  6. Book ; Thesis: Diagnostik der Borna-Disease-Virus-Infektion

    Hofer, Markus J.

    Evaluation einer neuen ELISA-Methode zum Nachweis von Serumantikörpern und direkter Virusnachweis in menschlichen Gehirnen

    1999  

    Author's details vorgelegt von Markus J. Hofer
    Language German
    Size 82 Bl., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Freiburg (Breisgau), Univ., Diss., 2001
    HBZ-ID HT013133365
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Mutational patterns in therapy-related acute lymphoblastic leukemia subgroups: one step closer to unveiling the genetic odyssey.

    Hofer, Kevin D / Bühler, Marco M / Roncador, Marco / Rechsteiner, Markus / Maggio, Ewerton M / Tchinda, Joëlle / Schanz, Urs / Haralambieva, Eugenia / Widmer, Corinne C

    Leukemia & lymphoma

    2024  , Page(s) 1–8

    Abstract: There is increasing evidence that therapy-related acute lymphoblastic leukemia (trALL) resulting from chemo- and/or radiotherapy represents a distinct entity. However, apart ... ...

    Abstract There is increasing evidence that therapy-related acute lymphoblastic leukemia (trALL) resulting from chemo- and/or radiotherapy represents a distinct entity. However, apart from
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.1080/10428194.2024.2315171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Schwer erreichbar

    Berger, Christa / Furrer, Beat / Geers, Peggy / Heer, Fridolin / Hofer, Gabriela / Matt, Mathias von / Niklaus, Annett / Theunert, Markus / Wullschleger, Christine

    (Laut & leise ; 2015, Nr. 3 (Oktober 2015))

    2015  

    Abstract: Nach wie vor profitieren vor allem gut situierte, selbstsichere und informierte Personen vom Angebot der Suchtprävention. Andere Menschen werden aus vielfältigen Gründen nicht oder nur ungenügend erreicht. Präventionsfachleute stehen vor der Aufgabe ... ...

    Author's details Mitarbeiter/innen dieser Nummer: Christa Berger, Beat Furrer, Peggy Geers, Fridolin Heer, Gabriela Hofer, Mathias von Matt, Annett Niklaus, Markus Theunert, Christine Wullschleger ; Herausgeber: Die Stellen für Suchtprävention im Kanton Zürich
    Series title Laut & leise ; 2015, Nr. 3 (Oktober 2015)
    Collection
    Abstract Nach wie vor profitieren vor allem gut situierte, selbstsichere und informierte Personen vom Angebot der Suchtprävention. Andere Menschen werden aus vielfältigen Gründen nicht oder nur ungenügend erreicht. Präventionsfachleute stehen vor der Aufgabe dieser Chancen-Ungleichheit entgegenzuwirken.
    Subject code 610 ; 360
    Language German
    Size 1 Online-Ressource (15 Seiten), Illustrationen
    Publisher Die Stellen für Suchtprävention im Kanton Zürich
    Publishing place Zürich
    Publishing country Switzerland
    Document type Book ; Online
    HBZ-ID HT019792297
    DOI 10.4126/FRL01-006409852
    Database Repository for Life Sciences

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  9. Article ; Online: CD8

    Spiteri, Alanna G / Suprunenko, Tamara / Cutts, Erin / Suen, Andrew / Ashhurst, Thomas M / Viengkhou, Barney / King, Nicholas J C / Hofer, Markus J

    Viruses

    2024  Volume 16, Issue 3

    Abstract: ... ...

    Abstract CD8
    MeSH term(s) Mice ; Animals ; Lymphocytic choriomeningitis virus ; CD8-Positive T-Lymphocytes ; Lymphocytic Choriomeningitis ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism ; Mice, Knockout ; Interferon Type I/metabolism ; Mice, Inbred C57BL
    Chemical Substances B7-H1 Antigen ; Programmed Cell Death 1 Receptor ; Interferon Type I
    Language English
    Publishing date 2024-03-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16030390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Re: Radical Prostatectomy or Watchful Waiting in Prostate Cancer-29-Year Follow-up.

    Hofer, Luisa / Hohenfellner, Markus

    European urology

    2019  Volume 75, Issue 6, Page(s) 1036

    MeSH term(s) Follow-Up Studies ; Humans ; Male ; Prostatectomy ; Prostatic Neoplasms/surgery ; Watchful Waiting
    Language English
    Publishing date 2019-02-28
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2019.02.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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