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  1. Article ; Online: Tuberculous Spondylodiscitis with Epidural Spread.

    Alay, Handan / Çankaya, Bahar Yılmaz

    Revista da Sociedade Brasileira de Medicina Tropical

    2023  Volume 56

    MeSH term(s) Humans ; Discitis/diagnostic imaging ; Tuberculosis ; Epidural Abscess ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-03-27
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0617-2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lumbar Tuberculous Spondylodiscitis with Abscess Formation.

    Alay, Handan / Çankaya, Bahar Yılmaz / Özden, Kemalettin

    Revista da Sociedade Brasileira de Medicina Tropical

    2024  Volume 57, Page(s) e009032024

    MeSH term(s) Humans ; Discitis/diagnostic imaging ; Abscess ; Tuberculosis, Spinal/diagnosis ; Tuberculosis, Spinal/diagnostic imaging
    Language English
    Publishing date 2024-02-05
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0502-2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Tuberculous Spondylodiscitis with Epidural Spread

    Handan Alay / Bahar Yılmaz Çankaya

    Revista da Sociedade Brasileira de Medicina Tropical, Vol

    2023  Volume 56

    Keywords Arctic medicine. Tropical medicine ; RC955-962
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical (SBMT)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Aquagenic syringeal acrokeratoderma in an adolescent female with COVID-19.

    Alay, Handan / Bilen, Handan

    Revista da Sociedade Brasileira de Medicina Tropical

    2021  Volume 54, Page(s) e0152

    MeSH term(s) Adolescent ; COVID-19 ; Female ; Humans ; SARS-CoV-2 ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2021-04-12
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0152-2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Aquagenic syringeal acrokeratoderma in an adolescent female with COVID-19

    Handan Alay / Handan Bilen

    Revista da Sociedade Brasileira de Medicina Tropical, Vol

    2021  Volume 54

    Keywords Arctic medicine. Tropical medicine ; RC955-962
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical (SBMT)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Can Endocan Be a Novel Marker in the Diagnosis of Brucellosis?

    Alay, Handan / Laloglu, Esra

    Vector borne and zoonotic diseases (Larchmont, N.Y.)

    2022  Volume 22, Issue 4, Page(s) 232–237

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Animals ; Biomarkers ; Brucellosis/diagnosis ; Brucellosis/veterinary
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-04-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2047199-3
    ISSN 1557-7759 ; 1530-3667
    ISSN (online) 1557-7759
    ISSN 1530-3667
    DOI 10.1089/vbz.2021.0103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Spondylodiscitis as osteoarticular involvement in brucellosis.

    Karadağ, Mehmet Kürşat / Alay, Handan / Çankaya, Bahar Yılmaz

    Revista da Sociedade Brasileira de Medicina Tropical

    2023  Volume 56

    MeSH term(s) Humans ; Discitis/diagnostic imaging ; Brucellosis/complications ; Brucellosis/diagnosis ; Arthritis, Infectious/diagnosis
    Language English
    Publishing date 2023-01-23
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0461-2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Brucellar Cervical Spondylodiscitis Complicated by Epidural Abscess and Neurobrucellosis.

    Alay, Handan / Karadağ, Mehmet Kürşat / Çankaya, Bahar Yılmaz

    Revista da Sociedade Brasileira de Medicina Tropical

    2023  Volume 56, Page(s) e0556

    MeSH term(s) Humans ; Epidural Abscess/complications ; Epidural Abscess/diagnostic imaging ; Discitis/diagnosis ; Discitis/diagnostic imaging ; Brucella ; Anti-Bacterial Agents/therapeutic use ; Brucellosis/complications ; Brucellosis/diagnosis ; Brucellosis/drug therapy ; Magnetic Resonance Imaging/adverse effects
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-02-20
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0556-2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Endocan as a potential marker in diagnosis and predicting disease severity in COVID-19 patients: a promising biomarker for patients with false-negative RT-PCR.

    Laloglu, Esra / Alay, Handan

    Upsala journal of medical sciences

    2022  Volume 12

    Abstract: Background: Endothelial-specific molecule 1 (endocan) has emerged as an inflammatory biomarker in recent years. The purpose of this study was to investigate the diagnostic value of serum endocan levels in the prediction of COVID-19 disease among ... ...

    Abstract Background: Endothelial-specific molecule 1 (endocan) has emerged as an inflammatory biomarker in recent years. The purpose of this study was to investigate the diagnostic value of serum endocan levels in the prediction of COVID-19 disease among patients with a false-negative reverse transcription polymerase change reaction (RT-PCR) test, and also to determine its correlation with the clinical severity of the disease.
    Methods: Thirty patients with positive RT-PCR results and 30 with false-negative RT-PCR results, both with suspected COVID-19 in terms of clinical, radiological, and laboratory findings, were included in the study. Thirty healthy controls were also enrolled.
    Results: Serum endocan levels were estimated to be 821.8 ± 99.3 pg/mL in COVID-19 RT-PCR (+) patients, 803.9 ± 97.0 pg/mL in RT-PCR false (-) patients with suspected COVID-19, and 382.9 ± 37.5 pg/mL in the control group. No significant difference was observed between RT-PCR (+) and RT-PCR false (-) patients (
    Conclusions: There is a need for different laboratory markers capable of assisting diagnosis and showing COVID-19 infection in suspected COVID-19 RT-PCR false-negative patients. Endocan levels can be used as an assistant blood test for identifying COVID-19 patients with false-negative RT-PCR tests and in determining the clinical severity of the disease.
    MeSH term(s) Biomarkers ; COVID-19 ; Humans ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Sensitivity and Specificity ; Severity of Illness Index
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-01-24
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 183949-4
    ISSN 2000-1967 ; 0300-9734
    ISSN (online) 2000-1967
    ISSN 0300-9734
    DOI 10.48101/ujms.v127.8211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Role of transforming growth factor-beta 1 and connective tissue growth factor levels in coronavirus disease-2019-related lung Injury: a prospective, observational, cohort study.

    Laloglu, Esra / Alay, Handan

    Revista da Sociedade Brasileira de Medicina Tropical

    2022  Volume 55, Page(s) e06152021

    Abstract: Background: Coronavirus disease-2019 (COVID-19) results in acute lung injury. This study examined the usefulness of serum transforming growth factor-beta 1 (TGF-β1) and connective tissue growth factor (CTGF) levels in predicting disease severity in ... ...

    Abstract Background: Coronavirus disease-2019 (COVID-19) results in acute lung injury. This study examined the usefulness of serum transforming growth factor-beta 1 (TGF-β1) and connective tissue growth factor (CTGF) levels in predicting disease severity in COVID-19 patients with pulmonary involvement.
    Methods: Fifty patients with confirmed COVID-19 and pulmonary involvement between September 2020, and February 2021 (Group 1) and 45 healthy controls (Group 2) were classified into three subgroups based on clinical severity: moderate, severe, and critical pneumonia. Serum TGF-β1 and CTGF concentrations were measured on days 1 and 7 of admission in Group 1 using an enzyme-linked immunosorbent assay. These concentrations were also measured in control cases. The mean serum TGF-β1 and CTGF levels were then compared among COVID-19 patients, based on clinical severity.
    Results: Significantly higher mean serum TGF-β1 and CTGF levels were observed on both days in Group 1 than in the control group. The mean serum TGF-β1 and CTGF levels on day 7 were also significantly higher than those on day 1 in Group 1. The critical patient group had the highest serum TGF-β1 and CTGF levels on both days, and the difference between this group and the moderate and severe pneumonia groups was significant. Cutoff values of 5.36 ng/mL for TGF-β1 and 626.2 pg/mL for CTGF emerged as predictors of COVID-19 with pulmonary involvement in receiver-operating characteristic curve analysis.
    Conclusions: TGF-β1 and CTGF are potential markers that can distinguish COVID-19 patients with pulmonary involvement and indicate disease severity. These findings may be useful for initiating treatment for early-stage COVID-19.
    MeSH term(s) COVID-19/complications ; Cohort Studies ; Connective Tissue Growth Factor/blood ; Humans ; Lung Diseases/virology ; Prospective Studies ; Transforming Growth Factor beta1/blood
    Chemical Substances TGFB1 protein, human ; Transforming Growth Factor beta1 ; Connective Tissue Growth Factor (139568-91-5)
    Language English
    Publishing date 2022-07-25
    Publishing country Brazil
    Document type Journal Article ; Observational Study
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0615-2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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