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  1. Article ; Online: Gas in the Eye, Holes in the Brain; "Bubble Trouble".

    Maramattom, Boby Varkey

    Neurology India

    2023  Volume 71, Issue 4, Page(s) 815–816

    MeSH term(s) Humans ; Brain/diagnostic imaging ; Head
    Language English
    Publishing date 2023-10-16
    Publishing country India
    Document type Letter
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.383855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Carotidynia or Transient Perivascular Inflammation of the Carotid Artery (TIPIC): A 5 O'Clock Shadow.

    Maramattom, Boby Varkey

    Neurology India

    2023  Volume 71, Issue 1, Page(s) 182–183

    MeSH term(s) Humans ; Carotid Artery, Common ; Carotid Artery Diseases/complications ; Carotid Artery Diseases/diagnostic imaging ; Autonomic Nervous System Diseases ; Pain ; Inflammation
    Language English
    Publishing date 2023-03-02
    Publishing country India
    Document type Journal Article
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.370472
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Acute ptotic myelopathy: cervical compressive myelopathy resulting from prolonged head ptosis after alcohol intoxication.

    Maramattom, Boby Varkey

    Clinical medicine (London, England)

    2023  Volume 23, Issue 5, Page(s) 515–517

    Abstract: A 28-year-old man was brought to the emergency department with quadriparesis of acute onset after a bout of binge drinking. Evaluation revealed a mid-cervical myelopathy and magnetic resonance imaging (MRI) showed an acute compressive cervical myelopathy. ...

    Abstract A 28-year-old man was brought to the emergency department with quadriparesis of acute onset after a bout of binge drinking. Evaluation revealed a mid-cervical myelopathy and magnetic resonance imaging (MRI) showed an acute compressive cervical myelopathy. He also developed rhabdomyolysis, and cervical paraspinal muscles showed MRI hyperintensities. After resolution of rhabdomyolysis and acute kidney injury, he underwent cervical spine fixation. He was found to have acute dropped head syndrome with secondary compressive myelopathy.
    MeSH term(s) Male ; Humans ; Adult ; Spinal Cord Compression/etiology ; Spinal Cord Compression/complications ; Alcoholic Intoxication/complications ; Spinal Cord Diseases/complications ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/pathology ; Cervical Vertebrae/surgery ; Magnetic Resonance Imaging ; Rhabdomyolysis/complications
    Language English
    Publishing date 2023-09-29
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.2023-0294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: FUEL for an 'Alice in Wonderland' syndrome.

    Maramattom, Boby Varkey

    Acta neurologica Belgica

    2022  Volume 123, Issue 4, Page(s) 1631–1633

    MeSH term(s) Humans ; Alice in Wonderland Syndrome ; Hallucinations
    Language English
    Publishing date 2022-12-06
    Publishing country Italy
    Document type Letter
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-022-02157-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Paroxysmal Dysarthria Ataxia-Tremor-Blepharospasm Syndrome in Bickerstaff Brainstem Encephalitis; A Variant of Paroxysmal Dysarthria Ataxia Syndrome.

    Maramattom, Boby Varkey

    Neurology India

    2022  Volume 70, Issue 1, Page(s) 437–438

    MeSH term(s) Ataxia/complications ; Blepharospasm ; Brain Stem ; Dysarthria/etiology ; Encephalitis/complications ; Humans ; Tremor
    Language English
    Publishing date 2022-03-09
    Publishing country India
    Document type Letter
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.338658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Self-Resolving Statin-Associated Myopathy with Rhabdomyolysis and Trismus.

    Maramattom, Boby Varkey

    Neurology India

    2022  Volume 70, Issue 4, Page(s) 1687–1688

    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Muscular Diseases/chemically induced ; Muscular Diseases/complications ; Rhabdomyolysis/chemically induced ; Rhabdomyolysis/complications ; Trismus/chemically induced ; Trismus/complications
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2022-09-08
    Publishing country India
    Document type Letter
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.355106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Myelin Oligodendrocyte Glycoprotein-Associated Disorders Post-ChAdOx1 Vaccination.

    Maramattom, Boby Varkey

    Cureus

    2022  Volume 14, Issue 3, Page(s) e23197

    Abstract: ChAdOx1 nCoV-19 vaccine (AstraZeneca) has been associated with rare adverse events following vaccination such as thrombosis with thrombocytopenia syndrome, inflammatory myositis, and autoimmune encephalitis. Para-infectious or post-infectious myelin ... ...

    Abstract ChAdOx1 nCoV-19 vaccine (AstraZeneca) has been associated with rare adverse events following vaccination such as thrombosis with thrombocytopenia syndrome, inflammatory myositis, and autoimmune encephalitis. Para-infectious or post-infectious myelin oligodendrocyte glycoprotein-associated disorders (MOGAD) have been reported in association with coronavirus disease. However, post-vaccine MOGAD (PV-MOGAD) has not yet been reported. Here, we report three cases of PV-MOGAD who presented with a prolonged severe headache after the ChAdOx1 vaccination. Other features of MOGAD such as optic neuritis or tumefactive demyelination appeared much later. Aseptic meningitis can be a presenting feature of PV-MOGAD. When patients present with a severe headache after the ChAdOx1 vaccination, PV-MOGAD should be considered along with thrombosis with thrombocytopenia syndrome.
    Language English
    Publishing date 2022-03-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.23197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Screening Power of Short Tau Inversion Recovery Muscle Magnetic Resonance Imaging in Critical Illness Myoneuropathy and Guillain-Barre Syndrome in the Intensive Care Unit.

    Maramattom, Boby Varkey

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2022  Volume 26, Issue 2, Page(s) 204–209

    Abstract: ... between CIMN and GBS.: How to cite this article: Maramattom BV. Screening Power of Short Tau Inversion ...

    Abstract Introduction: Critical illness myoneuropathy (CIMN) or intensive care unit (ICU)-acquired weakness (AW) is a common cause of weakness in ICU patients. Guillain-Barre syndrome (GBS) is also a common cause of acute neurological weakness in the ICU. It is diagnosed by clinical features, nerve conduction studies (NCS), and muscle/nerve biopsies.
    Methods: The short tau inversion recovery (STIR) muscle magnetic resonance (MR) images of seven patients with suspected CIMN and seven GBS patients over a 5-year period from February 2015 till May 2020 were analyzed.
    Results: All seven patients with CIMN showed diffuse muscle edema, predominating in the lower limbs. Only one patient with GBS showed abnormal magnetic resonance imaging (MRI) changes (14%) and MRI was normal in 86%. The sensitivity of MRI to detect CIMN was 100%, whereas the specificity was 85.7%. Thus, the positive predictive value (PPV) of MRI in this situation was 87.5% and the negative predictive value (NPV) was 100%.
    Conclusion: Muscle STIR imaging may help to differentiate between CIMN and GBS.
    How to cite this article: Maramattom BV. Screening Power of Short Tau Inversion Recovery Muscle Magnetic Resonance Imaging in Critical Illness Myoneuropathy and Guillain-Barre Syndrome in the Intensive Care Unit. Indian J Crit Care Med 2022;26(2):204-209.
    Language English
    Publishing date 2022-05-30
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Multiple Ischemic Strokes Due to Multisystem Inflammatory Syndrome in Adults (MIS-A).

    Maramattom, Boby Varkey

    Cureus

    2022  Volume 14, Issue 2, Page(s) e22103

    Abstract: Multisystem inflammatory syndrome in adults (MIS-A) is an extremely rare para-infectious or post-infectious complication of coronavirus disease 2019 (COVID-19) that requires prompt recognition and early treatment to avert severe morbidity and mortality. ... ...

    Abstract Multisystem inflammatory syndrome in adults (MIS-A) is an extremely rare para-infectious or post-infectious complication of coronavirus disease 2019 (COVID-19) that requires prompt recognition and early treatment to avert severe morbidity and mortality. A 55-year-old woman presented to us with fever, multiple ischemic strokes, thrombocytopenia, elevated inflammatory markers, and multiorgan dysfunction a few days after COVID-19 illness. She was severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-negative at admission. MRI showed multiple posterior circulation infarctions. She required intensive treatment with intravenous methylprednisolone (IVMP), intravenous immunoglobulin (IVIg), sustained low-efficiency dialysis (SLED), and plasmapheresis for disease remission. Initially, her presentation raised concern for thrombotic thrombocytopenic purpura, however, many features raised the suspicion of a multisystem inflammatory syndrome in adults (MIS-A). Our patient had increased levels of D-dimer, fibrinogen, interleukin 6 (IL-6), and large artery thromboembolism, A positive direct Coomb's test was also more suggestive of immune-mediated hemolysis rather than traction hemolysis, which is the pathophysiology of hemolytic anemia in TTP. Furthermore, MIS-A is known to present with gastrointestinal (GI) symptoms, whereas our case reports predominantly neurological symptoms with relative GI sparing. The overall inflammatory milieu secondary to MIS-A would have contributed to the formation of immune thrombosis, which would have embolized up the vertebrobasilar tree. The MR angiogram did not show any atherosclerotic changes, ruling out an atherosclerotic etiology, which is quite common in posterior circulation infarctions. Multiple courses of immunomodulatory treatment and prolonged treatment with steroids led to disease stabilization.
    Language English
    Publishing date 2022-02-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.22103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cerebral Amyloid Angiopathy with Lobar Haemorrhages and CAA-Related Inflammation in an Indian Family.

    Maramattom, Boby Varkey

    Cerebrovascular diseases extra

    2022  Volume 12, Issue 1, Page(s) 23–27

    Abstract: Introduction: Cerebral amyloid angiopathy (CAA) is a common cause of lobar intracerebral haemorrhage. Sporadic CAA is far more common than hereditary CAA (h-CAA). Familial CAA has not yet been described from India.: Case report: Two elderly Indian ... ...

    Abstract Introduction: Cerebral amyloid angiopathy (CAA) is a common cause of lobar intracerebral haemorrhage. Sporadic CAA is far more common than hereditary CAA (h-CAA). Familial CAA has not yet been described from India.
    Case report: Two elderly Indian women (a mother and daughter) presented 7 years apart with features of CAA. The mother had presented with features of CAA-related inflammation that responded to steroids, whereas the daughter presented with features of CAA-related intracerebral haemorrhage. Clinical exome testing did not reveal any known genetic variants associated with h-CAA.
    Discussion: Although clinical exome testing was inconclusive, the presentation of CAA in two generations (mother and daughter) in their 8th and 7th decades, respectively, raises the possibility of a familial CAA rather than a sporadic CAA in this Indian family. Genome-wide association studies are necessary to reveal if an Indian variant of familial CAA exists. We compare and contrast our familial CAA with the described h-CAA variants in the literature.
    MeSH term(s) Aged ; Cerebral Amyloid Angiopathy/complications ; Cerebral Amyloid Angiopathy/diagnostic imaging ; Cerebral Amyloid Angiopathy/genetics ; Cerebral Hemorrhage/etiology ; Cerebral Hemorrhage/genetics ; Female ; Genome-Wide Association Study ; Humans ; Inflammation ; Magnetic Resonance Imaging/adverse effects
    Language English
    Publishing date 2022-01-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2651613-5
    ISSN 1664-5456 ; 1664-5456
    ISSN (online) 1664-5456
    ISSN 1664-5456
    DOI 10.1159/000522214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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