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  1. Article: Imaging and neuropathological findings in patients with Post COVID-19 Neurological Syndrome-A review.

    Okrzeja, Jakub / Garkowski, Adam / Kubas, Bożena / Moniuszko-Malinowska, Anna

    Frontiers in neurology

    2023  Volume 14, Page(s) 1136348

    Abstract: Post COVID-19 syndrome is determined as signs and symptoms that appear during or after an infection consistent with SARS-CoV-2 disease, persist for more than 12 weeks and are not explained by an alternative diagnosis. This review presents the ... ...

    Abstract Post COVID-19 syndrome is determined as signs and symptoms that appear during or after an infection consistent with SARS-CoV-2 disease, persist for more than 12 weeks and are not explained by an alternative diagnosis. This review presents the neuropathological findings and imaging findings in Post COVID-19 Neurological Syndrome: the focal point is on the manifestations of involvement evident on brain and spine imaging.
    Language English
    Publishing date 2023-02-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2023.1136348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Case report: severe course of encephalitis of unknown origin.

    Okrzeja, Jakub / Czupryna, Piotr / Kubas, Bożena / Adamczuk, Justyna / Zajkowska, Joanna / Garkowski, Adam

    Przeglad epidemiologiczny

    2023  Volume 77, Issue 2, Page(s) 163–171

    Abstract: The exact cause of encephalitis is still unclear in many cases, although the common etiological factors of this process are viruses such as herpes simplex virus and rabies virus, and also bacteria, fungi, parasites, several medicines and autoimmune ... ...

    Abstract The exact cause of encephalitis is still unclear in many cases, although the common etiological factors of this process are viruses such as herpes simplex virus and rabies virus, and also bacteria, fungi, parasites, several medicines and autoimmune diseases. Herein, we report a case of a 56-year-old man with a history of amnestic syndrome, impaired consciousness, somnolence throughout the day, headache, dizziness and hypertension, who was admitted to hospital with suspected neurological disease, and imaging features that were consistent with encephalitis of unknown etiology. Methods which were used to examine patient: cerebrospinal fluid testing, PCR examinations for viruses, testing of antibodies against surface antigens, magnetic resonance imaging of the head, psychiatric consultation, oncology consultation. The objective of this study is to demonstrate a case about an uncommon neurologic condition, which every clinician might meet in clinical practice. In this type of cases, the use of steroids such as dexamethasone and methylprednisolone might lead to a full recovery.
    MeSH term(s) Male ; Humans ; Middle Aged ; Encephalitis, Herpes Simplex ; Poland
    Language English
    Publishing date 2023-10-16
    Publishing country Poland
    Document type Case Reports ; Journal Article
    ZDB-ID 421782-2
    ISSN 0033-2100
    ISSN 0033-2100
    DOI 10.32394/pe.77.16
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: A fatal case of tick-borne encephalitis in an immunocompromised patient: case report from Northeastern Poland and review of literature.

    Czarnowska, Agata / Groth, Monika / Okrzeja, Jakub / Garkowski, Adam / Kristoferitsch, Wolfgang / Kułakowska, Alina / Zajkowska, Joanna

    Ticks and tick-borne diseases

    2023  Volume 15, Issue 1, Page(s) 102273

    Abstract: Tick-borne encephalitis (TBE) is an infectious illness of the central nervous system caused by the TBE virus, which is commonly transmitted through a tick-bite. TBE is endemic in Europe and mid-Asia. In this study, we report a case of a 36-year-old woman, ...

    Abstract Tick-borne encephalitis (TBE) is an infectious illness of the central nervous system caused by the TBE virus, which is commonly transmitted through a tick-bite. TBE is endemic in Europe and mid-Asia. In this study, we report a case of a 36-year-old woman, living in Northeastern Poland, with a history of double corneal transplantation and post-transplant immunosuppressive therapy who was admitted to hospital because of progressive weakness, acute headache, nausea, vertigo, vomiting, and fever. The patient was diagnosed with TBE. However, the diagnosis was challenging as the initial serological tests for antibodies against the TBE virus were negative. We want to raise the awareness among the clinicians that the course of TBE is often unpredictable and that it tends to be more severe in immunocompromised individuals.. Delayed production of antibodies against TBE virus, which might inhibit the diagnosis of the disease, is observed in some immunocompromised patients.
    MeSH term(s) Female ; Humans ; Adult ; Encephalitis, Tick-Borne/epidemiology ; Poland ; Europe ; Asia ; Encephalitis Viruses, Tick-Borne ; Immunocompromised Host
    Language English
    Publishing date 2023-11-18
    Publishing country Netherlands
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 2541872-5
    ISSN 1877-9603 ; 1877-959X
    ISSN (online) 1877-9603
    ISSN 1877-959X
    DOI 10.1016/j.ttbdis.2023.102273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Imaging in Diagnosis of Systemic Sclerosis.

    Rutka, Katarzyna / Garkowski, Adam / Karaszewska, Katarzyna / Łebkowska, Urszula

    Journal of clinical medicine

    2021  Volume 10, Issue 2

    Abstract: Systemic sclerosis (SSc) is a connective tissue disease characterized by fibrosis in skin and internal organs, progressive vascular obliteration, and the production of autoantibodies. Diagnostic imaging is irreplaceable in both diagnosing and monitoring ... ...

    Abstract Systemic sclerosis (SSc) is a connective tissue disease characterized by fibrosis in skin and internal organs, progressive vascular obliteration, and the production of autoantibodies. Diagnostic imaging is irreplaceable in both diagnosing and monitoring patients suffering from systemic sclerosis. In addition to routinely used methods, such as comparative X-ray of the hands or a contrast-enhanced examination of the upper gastrointestinal tract or chest, there is an array of less widespread examinations, with an emphasis on magnetic resonance imaging (MRI) and ultrasonography, not only in the evaluation of the musculoskeletal system. This article will review the various imaging modalities available for SSc imaging and assessment, focusing on their utility as tissue-specific diagnosis and treatment monitoring.
    Language English
    Publishing date 2021-01-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10020248
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  5. Article: Case report: atypical presentation of acute disseminated encephalomyelitis after tick-borne encephalitis.

    Garkowski, Adam / Okrzeja, Jakub / Kubas, Bożena / Czupryna, Piotr / Zajkowska, Joanna / Kuchta, Adam / Moniuszko-Malinowska, Anna

    Oxford medical case reports

    2023  Volume 2023, Issue 12, Page(s) omad137

    Abstract: Acute disseminated encephalomyelitis (ADEM) is a rare and an immune- mediated inflammatory illness of the central nervous system that normally demonstrates as a monophasic disorder connected with multifocal neurologic symptoms. Herein, we report atypical ...

    Abstract Acute disseminated encephalomyelitis (ADEM) is a rare and an immune- mediated inflammatory illness of the central nervous system that normally demonstrates as a monophasic disorder connected with multifocal neurologic symptoms. Herein, we report atypical presentation of ADEM presenting as single lesions in a middle-aged woman after tick-borne encephalitis.
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Case Reports
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omad137
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  6. Article ; Online: Assessment of smell disturbances 6 months after COVID-19 in Polish population.

    Okrzeja, Jakub / Sołomacha, Sebastian / Alimowski, Maciej / Sowa, Paweł / Dubatówka, Marlena / Łapińska, Magda / Kiszkiel, Łukasz / Szczerbiński, Łukasz / Laskowski, Piotr Paweł / Czupryna, Piotr / Kubas, Bożena / Garkowski, Adam / Kamiński, Karol Adam / Moniuszko-Malinowska, Anna

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 11251

    Abstract: Considering the frequency and severity of olfactory disorders associated with SARS-CoV-2 infection, attention to the olfactory loss has expanded. The aim of our study was to assess of smell disturbances 6 months after COVID-19. The study population ... ...

    Abstract Considering the frequency and severity of olfactory disorders associated with SARS-CoV-2 infection, attention to the olfactory loss has expanded. The aim of our study was to assess of smell disturbances 6 months after COVID-19. The study population consisted of 2 groups: 196 Post-COVID-19 patients who were hospitalized because of COVID-19, control sample-130 patients without reported smell disorders from general population-Bialystok PLUS study. People from both groups were asked to participate in the Sniffin Sticks Test (half year after the disease). Sniffin Sticks Test consisted of 12 standardized smell samples. The participant's test score was counted based on correct scent recognition. Middle/older age was related with lower likelihood of olfaction recovery. The biggest differences in recognition of particular fragrances were observed for: orange and lemon, lemon and coffee (p.adj < 0.001). Patients had the greatest problem in assessing smell of lemon. The comparison of scores between Delta, Omicron, Wild Type, Wild Type Alpha waves showed statistically significant difference between Delta and Wild Type waves (p = 0.006). Duration of the disease (r = 0.218), age (r = -0.253), IL-6 (r = -0.281) showed significant negative correlations with the score. Statistically significant variables in the case of smell disorders were Omicron wave (CI = 0.045-0.902; P = 0.046) and Wild Type wave (CI = 0.135-0.716; P = 0.007) compared to Delta wave reference. Moreover, patients with PLT count below 150 000/μl had greater olfactory disorders than those with PLT count over 150 000/μl. There are: smell differences between post-COVID-19 patients and healthy population; statistically significant difference between Delta and Wild Type waves in Post-COVID-19 group in score of the Sniffin Sticks Test. Smell disturbances depend on the age, cognitive impairments, clinical characteristics of the COVID-19 disease and sex of the patient.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/complications ; Male ; Female ; Middle Aged ; Poland/epidemiology ; Olfaction Disorders/epidemiology ; Olfaction Disorders/etiology ; Olfaction Disorders/virology ; Aged ; Adult ; SARS-CoV-2/isolation & purification ; Smell/physiology
    Language English
    Publishing date 2024-05-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-62114-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Fahr syndrome - an incidental finding in a patient with lymphocytic meningitis.

    Okrzeja, Jakub / Narejko, Karolina / Tarasów, Eugeniusz / Zajkowska, Joanna / Garkowski, Adam

    Radiology case reports

    2021  Volume 16, Issue 12, Page(s) 3855–3858

    Abstract: Fahr syndrome is a rare condition mainly characterized by symmetric and bilateral calcification of basal ganglia and cerebellar nuclei. Herein, we report a case of a 67-year-old woman with a history of parathyroidectomy and Parkinsonism, who was admitted ...

    Abstract Fahr syndrome is a rare condition mainly characterized by symmetric and bilateral calcification of basal ganglia and cerebellar nuclei. Herein, we report a case of a 67-year-old woman with a history of parathyroidectomy and Parkinsonism, who was admitted to hospital with suspected neuroinfection, and imaging features that were consistent with Fahr syndrome. The objective of this study is to teach clinicians about a neurologic illness that requires comprehensive medical and neurologic investigation due to the manifestations of lymphocytic meningitis might distract you from Fahr syndrome symptoms.
    Language English
    Publishing date 2021-10-11
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2021.09.025
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  8. Article ; Online: Imaging in Diagnosis of Systemic Sclerosis

    Katarzyna Rutka / Adam Garkowski / Katarzyna Karaszewska / Urszula Łebkowska

    Journal of Clinical Medicine, Vol 10, Iss 2, p

    2021  Volume 248

    Abstract: Systemic sclerosis (SSc) is a connective tissue disease characterized by fibrosis in skin and internal organs, progressive vascular obliteration, and the production of autoantibodies. Diagnostic imaging is irreplaceable in both diagnosing and monitoring ... ...

    Abstract Systemic sclerosis (SSc) is a connective tissue disease characterized by fibrosis in skin and internal organs, progressive vascular obliteration, and the production of autoantibodies. Diagnostic imaging is irreplaceable in both diagnosing and monitoring patients suffering from systemic sclerosis. In addition to routinely used methods, such as comparative X-ray of the hands or a contrast-enhanced examination of the upper gastrointestinal tract or chest, there is an array of less widespread examinations, with an emphasis on magnetic resonance imaging (MRI) and ultrasonography, not only in the evaluation of the musculoskeletal system. This article will review the various imaging modalities available for SSc imaging and assessment, focusing on their utility as tissue-specific diagnosis and treatment monitoring.
    Keywords systemic sclerosis ; imaging ; X-ray ; ultrasound ; computed tomography ; magnetic resonance imaging ; Medicine ; R
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Severe tick-borne encephalitis in a patient recovered from COVID 19.

    Czarnowska, Agata / Kapica-Topczewska, Katarzyna / Garkowski, Adam / Chorąży, Monika / Tarasiuk, Joanna / Kochanowicz, Jan / Kułakowska, Alina / Zajkowska, Joanna

    Ticks and tick-borne diseases

    2022  Volume 13, Issue 4, Page(s) 101940

    Abstract: North-eastern Poland is an endemic region for tick-borne encephalitis (TBE). The COVID-19 pandemic overlapped with the activity period of ticks that are the main vectors for TBE. As we know from short observation worldwide, SARS-CoV-2 virus affects ... ...

    Abstract North-eastern Poland is an endemic region for tick-borne encephalitis (TBE). The COVID-19 pandemic overlapped with the activity period of ticks that are the main vectors for TBE. As we know from short observation worldwide, SARS-CoV-2 virus affects significantly the immune system and can lead to serious complications of other infections even in previously healthy patients. A 24-year-old female patient, who lived close to the forest, was admitted to the Department of Neurology at Medical University of Bialystok with fever, dizziness, and progressive left-sided hemiparesis for three days. She had no medical history of chronic disease and was not vaccinated against TBE. The patient had SARS-CoV-2 infection three weeks prior to admission to the hospital (positive IgG against SARS-CoV-2). During COVID-19 infection she had fever, myalgia, a mild dyspnoea without indications for oxygen therapy and recovered after one week. During hospitalisation in the Department of Neurology the patient presented neck stiffness, progressing tetraparesis, dysarthria and weakness of the neck muscles. The magnetic resonance of the head revealed numerous lesions, mainly in both thalamus, longitudinal lesion was found in the cervical spinal cord. The cerebrospinal fluid analysis indicated lymphocytic inflammation. A high level of TBE antibodies in both serum and CSF was found. After immunoglobulin and symptomatic treatment her condition gradually improved. The recovery after SARS-CoV-2 infection overlapping with TBE might have influenced the course of tick-borne disease in a bad manner. The correct diagnosis can be a challenge as COVID-19 can lead to further complications, also neurological. The co-incidence we observed is very rare, however during the pandemic it is pivotal to remember about possible occurrence of other infections and their atypical course.
    MeSH term(s) Adult ; COVID-19 ; Encephalitis Viruses, Tick-Borne ; Encephalitis, Tick-Borne/complications ; Encephalitis, Tick-Borne/diagnosis ; Encephalitis, Tick-Borne/epidemiology ; Female ; Fever ; Humans ; Pandemics ; SARS-CoV-2 ; Young Adult
    Language English
    Publishing date 2022-03-12
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 2541872-5
    ISSN 1877-9603 ; 1877-959X
    ISSN (online) 1877-9603
    ISSN 1877-959X
    DOI 10.1016/j.ttbdis.2022.101940
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  10. Article: Imaging of Lyme Neuroborreliosis: A Pictorial Review.

    Garkowski, Adam / Łebkowska, Urszula / Kubas, Bożena / Garkowska, Ewa / Rutka, Katarzyna / Gawarecka, Elwira / Zajkowska, Joanna

    Open forum infectious diseases

    2020  Volume 7, Issue 10, Page(s) ofaa370

    Abstract: Lyme neuroborreliosis is a common feature ... ...

    Abstract Lyme neuroborreliosis is a common feature of
    Language English
    Publishing date 2020-08-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofaa370
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