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  1. Article ; Online: La administración nocturna de la medicación antihipertensiva no es más beneficiosa que la matutina para la prevención de eventos cardiovasculares mayores

    Jessica Barochiner

    Evidencia. Actualización en la Práctica Ambulatoria, Vol 26, Iss

    2023  Volume 1

    Keywords Medicine (General) ; R5-920
    Language Spanish
    Publishing date 2023-03-01T00:00:00Z
    Publisher Fundacion MF
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Orthostatic hypotension, arterial stiffness and home blood pressure variability: an opportunity for looking beyond the horizon.

    Barochiner, Jessica

    Journal of hypertension

    2020  Volume 38, Issue 10, Page(s) 2075–2076

    MeSH term(s) Aged ; Biomarkers ; Blood Pressure ; Cross-Sectional Studies ; Humans ; Hypotension, Orthostatic ; Vascular Stiffness
    Chemical Substances Biomarkers
    Language English
    Publishing date 2020-09-01
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 605532-1
    ISSN 1473-5598 ; 0263-6352 ; 0952-1178
    ISSN (online) 1473-5598
    ISSN 0263-6352 ; 0952-1178
    DOI 10.1097/HJH.0000000000002557
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1885: Show issues Location:
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    Zs.MO 614: Show issues

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  3. Article ; Online: El control intensivo de la presión arterial en pacientes sin diabetes con enfermedad renal crónica no reduciría la progresión de la enfermedad renal

    Jessica Barochiner

    Evidencia. Actualización en la Práctica Ambulatoria, Vol 21, Iss

    2019  Volume 4

    Keywords Medicine (General) ; R5-920
    Language Spanish
    Publishing date 2019-01-01T00:00:00Z
    Publisher Fundacion MF
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Prevalence and Characteristics of Isolated Nocturnal Hypertension and Masked Nocturnal Hypertension in a Tertiary Hospital in the City of Buenos Aires.

    Barochiner, Jessica / Díaz, Romina R / Martínez, Rocío

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 8

    Abstract: Isolated nocturnal hypertension (INH) and masked nocturnal hypertension (MNH) increase cardiovascular risk. Their prevalence and characteristics are not clearly established and seem to differ among populations. We aimed to determine the prevalence and ... ...

    Abstract Isolated nocturnal hypertension (INH) and masked nocturnal hypertension (MNH) increase cardiovascular risk. Their prevalence and characteristics are not clearly established and seem to differ among populations. We aimed to determine the prevalence and associated characteristics of INH and MNH in a tertiary hospital in the city of Buenos Aires. We included 958 hypertensive patients ≥ 18 years who underwent an ambulatory blood pressure monitoring (ABPM) between October and November 2022, as prescribed by their treating physician to diagnose or to assess hypertension control. INH was defined as nighttime BP ≥ 120 mmHg systolic or ≥70 diastolic in the presence of normal daytime BP (<135/85 mmHg regardless of office BP; MNH was defined as the presence of INH with office BP < 140/90 mmHg). Variables associated with INH and MNH were analyzed. The prevalences of INH and MNH were 15.7% (95% CI 13.5-18.2%) and 9.7 (95% CI 7.9-11.8%), respectively. Age, male sex, and ambulatory heart rate were positively associated with INH, whereas office BP, total cholesterol, and smoking habits showed a negative association. In turn, diabetes and nighttime heart rate were positively associated with MNH. In conclusion, INH and MNH are frequent entities, and determination of clinical characteristics such as those detected in this study is critical since this might contribute to a more appropriate use of resources.
    Language English
    Publishing date 2023-04-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13081419
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  5. Article ; Online: El tratamiento antihipertensivo podría aumentar el riesgo cardiovascular en pacientes con diabetes y presión arterial sistólica menor de 140 mmHg

    Jessica Barochiner

    Evidencia. Actualización en la Práctica Ambulatoria, Vol 20, Iss

    2017  Volume 1

    Keywords Medicine (General) ; R5-920
    Language Spanish
    Publishing date 2017-04-01T00:00:00Z
    Publisher Fundacion MF
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Use of inhibitors of the renin-angiotensin system in hypertensive patients and COVID-19 severity: A systematic review and meta-analysis.

    Barochiner, Jessica / Martínez, Rocío

    Journal of clinical pharmacy and therapeutics

    2020  Volume 45, Issue 6, Page(s) 1244–1252

    Abstract: What is known and objective: Controversy has arisen in the scientific community on whether the use of renin-angiotensin system (RAS) inhibitors in the context of COVID-19 would be beneficial or harmful. A meta-analysis of eligible studies comparing the ... ...

    Abstract What is known and objective: Controversy has arisen in the scientific community on whether the use of renin-angiotensin system (RAS) inhibitors in the context of COVID-19 would be beneficial or harmful. A meta-analysis of eligible studies comparing the occurrence of severe and fatal COVID-19 in infected hypertensive patients who were under treatment with angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) vs no treatment or other antihypertensives was conducted.
    Methods: PubMed, Google Scholar, the Cochrane Library, medRxiv and bioRxiv were searched for relevant studies. Fixed-effects models or random-effects models were used depending on the heterogeneity between estimates.
    Results and discussion: A total of eighteen studies with 17 311 patients were included. The use of RAS inhibitors was associated with a significant 16% decreased risk of the composite outcome (death, admission to intensive care unit, mechanical ventilation requirement or progression to severe or critical pneumonia): RR: 0.84 (95% CI: 0.73-0.95), P = .007, I
    What is new and conclusion: The results of this pooled analysis suggest that the use of ACEI/ARB does not worsen the prognosis of COVID-19, and could even be protective in hypertensive subjects. Hypertensive patients should continue these drugs even if they become infected with SARS-CoV-2.
    MeSH term(s) Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Antihypertensive Agents/therapeutic use ; COVID-19/complications ; Humans ; Hypertension/complications ; Hypertension/drug therapy ; Renin-Angiotensin System/drug effects ; Severity of Illness Index
    Chemical Substances Angiotensin-Converting Enzyme Inhibitors ; Antihypertensive Agents
    Keywords covid19
    Language English
    Publishing date 2020-08-07
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 639006-7
    ISSN 1365-2710 ; 0269-4727
    ISSN (online) 1365-2710
    ISSN 0269-4727
    DOI 10.1111/jcpt.13246
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  7. Article ; Online: La clortalidona no se asocia con menos eventos cardiovasculares o muerte que la hidroclorotiazida en ancianos y presenta una mayor incidencia de hipokalemia

    Jessica Barochiner

    Evidencia. Actualización en la Práctica Ambulatoria, Vol 18, Iss

    2015  Volume 1

    Keywords Medicine (General) ; R5-920
    Language Spanish
    Publishing date 2015-04-01T00:00:00Z
    Publisher Fundacion MF
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Prognostic value of home blood pressure monitoring in patients under antihypertensive treatment.

    Barochiner, Jessica / Aparicio, Lucas S / Martínez, Rocío / Boggia, José

    Journal of human hypertension

    2022  Volume 37, Issue 9, Page(s) 775–782

    Abstract: The prognostic value of home blood pressure monitoring (HBPM) has been investigated in several studies in the general population, demonstrating its independent association with cardiovascular events. However, in the case of treated hypertensive subjects, ...

    Abstract The prognostic value of home blood pressure monitoring (HBPM) has been investigated in several studies in the general population, demonstrating its independent association with cardiovascular events. However, in the case of treated hypertensive subjects, evidence is controversial. Our purpose was to evaluate the prognostic value of HBPM in this population. Medicated hypertensive patients who performed a 4-day HBPM (Omron® HEM-705CP-II) between 2008 and 2015 were followed up for a median of 5.9 years, registering the occurrence of a composite primary outcome of fatal and non-fatal cardiovascular events. Cox regression models were used to analyze the prognostic value of HBPM, considering 4-day measurements, discarding the first day, and analyzing morning, afternoon and evening periods separately. We included 1582 patients in the analysis (33.4% men, median age 70.8 years, on an average of 2.1 antihypertensive drugs). During follow-up, 273 events occurred. HBPM was significantly associated with cardiovascular events in all five scenarios in the unadjusted models. When adjusting for office BP and other cardiovascular risk factors, the association remained marginally significant for the 4-day period, discarding first-day measurements HBPM (HR 1.04 [95% CI 1-1.1] and 1.04 [95% CI 1-1.1], respectively) and statistically significant for all separate periods of measurement: HR 1.32 (95% CI 1.01-1.72); 1.33 (95% CI 1.02-1.72); and 1.30 (95% CI 1.01-1.67), for morning, afternoon and evening, respectively. When analyzing separately fatal and non-fatal events, statistical significance was held for the former only. In conclusion, HBPM is an independent predictor of cardiovascular events in hypertensives under treatment.
    MeSH term(s) Male ; Humans ; Aged ; Female ; Antihypertensive Agents/adverse effects ; Prognosis ; Blood Pressure Monitoring, Ambulatory ; Reproducibility of Results ; Hypertension/diagnosis ; Hypertension/drug therapy
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2022-09-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/s41371-022-00758-x
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    Zs.A 2380: Show issues Location:
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  9. Article ; Online: Novel Indices of Home Blood Pressure Variability and Hypertension-Mediated Organ Damage in Treated Hypertensive Patients.

    Barochiner, Jessica / Martínez, Rocío / Aparicio, Lucas S

    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension

    2021  Volume 28, Issue 4, Page(s) 365–372

    Abstract: Introduction: Although multiple home blood pressure variability (HBPV) indices have been proposed, the superiority of one over another is not clear in treated hypertensives.: Aim: We evaluated the correlation between different indices of HBPV and ... ...

    Abstract Introduction: Although multiple home blood pressure variability (HBPV) indices have been proposed, the superiority of one over another is not clear in treated hypertensives.
    Aim: We evaluated the correlation between different indices of HBPV and hypertension-mediated organ damage (HMOD) in this population and determined predictors of greater HBPV.
    Methods: We included adult treated hypertensives who performed an HBP monitoring (duplicate sitting BP readings in the morning, afternoon, and evening for 4 days, Omron HEM-705CP-II), laboratory measurements, transthoracic echocardiogram and carotid-femoral pulse wave velocity. We selected HBPV indices from three different calculation approaches: coefficient of variation (CoV), difference between maximum and minimum BP (MMD), and morning BP increase (MI), and evaluated their correlation with left ventricular mass index, relative wall thickness (RWT), ejection fraction, arterial stiffness and estimated glomerular filtration rate through a correlation matrix. For those variability indices significantly associated with HMOD, we constructed multiple linear regression models to determine independent predictors of HBPV.
    Results: We included 204 patients, mean age 67.2 (± 13.8) years, 64% female. CoV and MMD for systolic BP showed the greatest correlation with HMOD. Factors independently associated both with CoV and MMD were: older age (b = 0.07; 95% CI 0.04-0.07; p < 0.001 and b = 0.4; 95% CI 0.2-0.5; p < 0.001, respectively), history of stroke (b = 3.6; 95% CI 0.9-6.4; p = 0.01 and b = 25.7; 95% CI 10.1-41.2; p = 0.001, respectively), and body mass index [b = - 0.1; 95% CI - 0.2 to (- 0.02); p = 0.01 and b = - 0.5; 95% CI - 0.9 to (- 0.1); p = 0.01, respectively].
    Conclusion: CoV and MMD showed the greatest association with HMOD in treated hypertensives. Older age, history of stroke and lower body mass index were easy-to-detect predictors.
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; Blood Pressure ; Blood Pressure Monitoring, Ambulatory ; Body Mass Index ; Cross-Sectional Studies ; Female ; Heart Diseases/diagnosis ; Heart Diseases/etiology ; Heart Diseases/physiopathology ; Humans ; Hypertension/complications ; Hypertension/diagnosis ; Hypertension/physiopathology ; Hypertension/therapy ; Kidney Diseases/diagnosis ; Kidney Diseases/etiology ; Kidney Diseases/physiopathology ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Reproducibility of Results ; Risk Assessment ; Risk Factors ; Stroke/diagnosis ; Stroke/physiopathology
    Language English
    Publishing date 2021-04-21
    Publishing country New Zealand
    Document type Comparative Study ; Journal Article
    ZDB-ID 1236337-6
    ISSN 1179-1985 ; 1120-9879
    ISSN (online) 1179-1985
    ISSN 1120-9879
    DOI 10.1007/s40292-021-00453-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4289: Show issues Location:
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  10. Article ; Online: Use of inhibitors of the renin‐angiotensin system in hypertensive patients and COVID‐19 severity

    Barochiner, Jessica / Martínez, Rocío

    Journal of Clinical Pharmacy and Therapeutics ; ISSN 0269-4727 1365-2710

    A systematic review and meta‐analysis

    2020  

    Keywords Pharmacology (medical) ; Pharmacology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/jcpt.13246
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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