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  1. Article ; Online: Area of residence and hypertension risk: need more evidence from low- and middle-income countries.

    Gupta, Rajat Das

    Hypertension research : official journal of the Japanese Society of Hypertension

    2023  Volume 46, Issue 6, Page(s) 1442–1443

    MeSH term(s) Humans ; Developing Countries/statistics & numerical data ; Nepal ; Hypertension/epidemiology ; Demography ; Residence Characteristics
    Language English
    Publishing date 2023-04-07
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1175297-x
    ISSN 1348-4214 ; 0916-9636
    ISSN (online) 1348-4214
    ISSN 0916-9636
    DOI 10.1038/s41440-023-01278-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3898: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Multiple Cardiac Rhabdomyomas in Dizygotic Twins.

    Dhindsa, Amreen / Gupta, Rajat

    CASE (Philadelphia, Pa.)

    2023  Volume 7, Issue 3, Page(s) 109–112

    Language English
    Publishing date 2023-01-31
    Publishing country United States
    Document type Case Reports
    ISSN 2468-6441
    ISSN (online) 2468-6441
    DOI 10.1016/j.case.2022.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Causal Gene Confusion: The Complicated

    Gupta, Rajat M

    Arteriosclerosis, thrombosis, and vascular biology

    2022  Volume 42, Issue 5, Page(s) 610–612

    MeSH term(s) Coronary Artery Disease/genetics ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Polymorphism, Single Nucleotide
    Language English
    Publishing date 2022-04-07
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1221433-4
    ISSN 1524-4636 ; 1079-5642
    ISSN (online) 1524-4636
    ISSN 1079-5642
    DOI 10.1161/ATVBAHA.122.317539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1705: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: The Aging Aorta: Are We Only as Old as Our Endothelium?

    Gupta, Rajat M / Plutzky, Jorge

    Arteriosclerosis, thrombosis, and vascular biology

    2022  Volume 42, Issue 2, Page(s) 172–174

    MeSH term(s) Aorta ; Endothelium
    Language English
    Publishing date 2022-01-26
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1221433-4
    ISSN 1524-4636 ; 1079-5642
    ISSN (online) 1524-4636
    ISSN 1079-5642
    DOI 10.1161/ATVBAHA.121.317275
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1705: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Achieving Correct Axis and Good Depth in Gender Affirming Vaginoplasties by Penile-Perineoscrotal Flap Vaginoplasty.

    Gupta, Richie / Gupta, Rajat

    Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India

    2022  Volume 55, Issue 2, Page(s) 188–195

    Abstract: ... ...

    Abstract Objectives
    Language English
    Publishing date 2022-07-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2118680-7
    ISSN 1998-376X ; 0970-0358
    ISSN (online) 1998-376X
    ISSN 0970-0358
    DOI 10.1055/s-0041-1740530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Strategies to Improve Electrical Conductivity in Metal-Organic Frameworks: A Comparative Study.

    Saha, Rajat / Gupta, Kajal / Gómez García, Carlos J

    Crystal growth & design

    2024  Volume 24, Issue 5, Page(s) 2235–2265

    Abstract: Metal-organic frameworks (MOFs), formed by the combination of both inorganic and organic components, have attracted special attention for their tunable porous structures, chemical and functional diversities, and enormous applications in gas storage, ... ...

    Abstract Metal-organic frameworks (MOFs), formed by the combination of both inorganic and organic components, have attracted special attention for their tunable porous structures, chemical and functional diversities, and enormous applications in gas storage, catalysis, sensing, etc. Recently, electronic applications of MOFs like electrocatalysis, supercapacitors, batteries, electrochemical sensing, etc., have become a major research topic in MOF chemistry. However, the low electrical conductivity of most MOFs represents a major handicap in the development of these emerging applications. To overcome these limitations, different strategies have been developed to enhance electrical conductivity of MOFs for their implementation in electronic devices. In this review, we outline all these strategies employed to increase the electronic conduction in both intrinsically (framework-modulated) and extrinsically (guests-modulated) conducting MOFs.
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1528-7483
    ISSN 1528-7483
    DOI 10.1021/acs.cgd.3c01162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Role of Endothelial Cells in Atherosclerosis: Insights from Genetic Association Studies.

    Pepin, Mark E / Gupta, Rajat M

    The American journal of pathology

    2023  Volume 194, Issue 4, Page(s) 499–509

    Abstract: Endothelial cells (ECs) mediate several biological functions that are relevant to atherosclerosis and coronary artery disease (CAD), regulating an array of vital processes including vascular tone, wound healing, reactive oxygen species, shear stress ... ...

    Abstract Endothelial cells (ECs) mediate several biological functions that are relevant to atherosclerosis and coronary artery disease (CAD), regulating an array of vital processes including vascular tone, wound healing, reactive oxygen species, shear stress response, and inflammation. Although which of these functions is linked causally with CAD development and/or progression is not yet known, genome-wide association studies have implicated more than 400 loci associated with CAD risk, among which several have shown EC-relevant functions. Given the arduous process of mechanistically interrogating single loci to CAD, high-throughput variant characterization methods, including pooled Clustered Regularly Interspaced Short Palindromic Repeats screens, offer exciting potential to rapidly accelerate the discovery of bona fide EC-relevant genetic loci. These discoveries in turn will broaden the therapeutic avenues for CAD beyond lipid lowering and behavioral risk modification to include EC-centric modalities of risk prevention and treatment.
    MeSH term(s) Humans ; Endothelial Cells ; Genome-Wide Association Study ; Atherosclerosis/genetics ; Coronary Artery Disease/genetics ; Inflammation/genetics ; Polymorphism, Single Nucleotide
    Language English
    Publishing date 2023-10-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2943-9
    ISSN 1525-2191 ; 0002-9440
    ISSN (online) 1525-2191
    ISSN 0002-9440
    DOI 10.1016/j.ajpath.2023.09.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.76: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Insights into Prospects of Novel NSAID Prodrugs in the Management of Gastrointestinal Toxicity: A Perspective Review.

    Goyal, Rajat / Gupta, Sumeet / Sharma, Prabodh / Sharma, Manu

    Recent advances in inflammation & allergy drug discovery

    2024  

    Abstract: Non-steroidal anti-inflammatory drugs (NSAIDs) have a long history in the healthcare system due to their therapeutic potential. These NSAIDs cause ulcerogenicity, stomach pains, gastrointestinal hemorrhage, mucosa bleeding, and pancreatitis when used ... ...

    Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) have a long history in the healthcare system due to their therapeutic potential. These NSAIDs cause ulcerogenicity, stomach pains, gastrointestinal hemorrhage, mucosa bleeding, and pancreatitis when used moderately and consistently. With researchers, managing the aforementioned adverse effects therapeutically is getting increasingly difficult. One method for creating NSAID moieties with low penetration as well as ulcerogenic properties is the prodrug technique. During the oral consumption of NSAID-prodrugs, ulcerations, intestinal hemorrhage, and mucosa hemorrhage have significantly decreased. Considering this background, this review focussed on NSAID prodrugs as well as their justifications, the pathogenesis of NSAIDs inducing gastrointestinal toxicity, and the role of different antioxidants and spacer groups. Prodrug moieties have more advantages over parent medicines concerning both solubility and lipophilicity. In general, NSAID-class prodrugs can successfully treat both acute and long-term inflammation and aches without causing ulcerotoxicity and related gastrointestinal side effects, which reduces their burden from the pharmacoeconomic perspective.
    Language English
    Publishing date 2024-01-23
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2772-2716
    ISSN (online) 2772-2716
    DOI 10.2174/0127722708278736231205055035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Isolating pollen signals from laser diode aerosol Optical Particle Counter (OPC) data through positive matrix factorization (PMF) and Unmix receptor models.

    Singhal, Rajat Prakash / Khandelwal, Sumit / Gupta, A B

    The Science of the total environment

    2024  , Page(s) 172793

    Abstract: Pollen, a significant natural bioaerosol and allergen for sensitized individuals, is expected to increase in prevalence due to climate change. Mitigating allergy symptoms involves avoiding pollen exposure and pre-medication, emphasizing the importance of ...

    Abstract Pollen, a significant natural bioaerosol and allergen for sensitized individuals, is expected to increase in prevalence due to climate change. Mitigating allergy symptoms involves avoiding pollen exposure and pre-medication, emphasizing the importance of real-time knowledge of localized ambient air pollen concentrations. Laser diode Optical Particle Counters (OPCs) are commonly used for monitoring particle number concentrations in ambient air. This study explores the hypothesis that OPCs can monitor pollen but may struggle to distinguish them from other particles. We aimed to isolate the pollen signal from collective particle number concentrations using source apportionment models, specifically Positive Matrix Factorization (PMF) and Unmix, applied to multiple bin OPC data. The pollen signals isolated using PMF show slightly better correlation values than those isolated using Unmix. PMF-derived pollen signals exhibit strong correlations with Holoptelea (r = 0.64) and total pollen (r = 0.54) concentrations, while a moderate correlation is observed with Poaceae (r = 0.47). Exclusion of low pollen events strengthens correlations for Holoptelea and Poaceae to very strong (r = 0.87) and strong (r = 0.67), respectively. Although both model types effectively isolate the pollen signal, metrics suggest that Unmix has the potential for more accurate predictions of both moderate and extreme pollen events simultaneously. The Mean Absolute Error (MAE), Root Mean Square Error (RMSE), and Relative Root Mean Square Error (RRMSE) metrics for Holoptelea are 46.2 grains m
    Language English
    Publishing date 2024-04-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.172793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: Evaluation of residential demand response trials with smart heat pumps and batteries and their effect at the substation feeder

    Gupta, Rajat / Morey, Johanna

    Journal of Cleaner Production. 2023 June, v. 403 p.136760-

    2023  

    Abstract: Residential demand response using low carbon technologies can potentially offer energy flexibility to the electricity network along with integration of renewable generation. This paper seeks to empirically evaluate the effectiveness of residential demand ...

    Abstract Residential demand response using low carbon technologies can potentially offer energy flexibility to the electricity network along with integration of renewable generation. This paper seeks to empirically evaluate the effectiveness of residential demand response trials on a low voltage feeder of a secondary substation in Barnsley (UK). The study used a sample of 14 well-insulated dwellings equipped with home batteries, heat pumps and solar photovoltaic systems coordinated using automated control. Statistical analysis was undertaken using time-series monitoring data obtained at the individual dwelling level, dwelling sample and at the feeder level of the local low voltage network. Resident experience of the trials was assessed through qualitative data obtained from household telephone surveys. Over three weeks of trials, daily demand response interventions of 2 h duration were applied to the sample of 14 dwellings. For evening peak times, the mean reduction in grid electricity import was found to be 1.3 kWh (67%) per dwelling for turn-down interventions which aimed to minimise import. For turn-up interventions between 1 and 3 pm, the mean increase in grid electricity import was found to be 5.8 kWh (645%) per dwelling. The effect of interventions was measured at the low voltage network level for two single-phase feeders, where penetration of trial homes was approximately one-third. A reduction in mean real power up to 21% was observed for turn-down interventions as well as an increase in real mean power up to 307% for turn-up interventions. In general, the trials had little effect on residents in terms of thermal comfort, hot water availability, noise disturbance or disruption to routines, and where such effects were noticed, they were broadly acceptable. The widespread implementation of residential demand response schemes will require increased roll-out of time-of-use tariffs, enhanced resident support and extensive monitoring of low voltage feeders in electricity substations.
    Keywords automation ; carbon ; electric potential difference ; electricity ; heat ; imports ; statistical analysis ; telephones ; time series analysis ; Residential demand response ; Low voltage network ; Low carbon technologies ; Energy flexibility ; Grid impact ; Field trial
    Language English
    Dates of publication 2023-06
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Use and reproduction
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2023.136760
    Database NAL-Catalogue (AGRICOLA)

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