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  1. Book: Challenges in pulmonary hypertension

    Marra, Alberto M.

    (Heart failure clinics ; volume 19, number 1 (January 2023))

    2023  

    Author's details editors Alberto M. Marra, Alexander E. Sherman, Pietro Ameri
    Series title Heart failure clinics ; volume 19, number 1 (January 2023)
    Collection
    Language English
    Size xvi, 152 Seiten, Illustrationen
    Publisher Elsevier
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT021695603
    ISBN 978-0-323-93877-8 ; 0-323-93877-9
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Clinical and non-clinical determinants of pulmonary arterial hypertension development in severe autoimmune rheumatic diseases.

    Arcopinto, Michele / Marra, Alberto M

    Rheumatology (Oxford, England)

    2021  Volume 61, Issue 1, Page(s) 1–2

    MeSH term(s) Familial Primary Pulmonary Hypertension ; Humans ; Pulmonary Arterial Hypertension ; Rheumatic Diseases/complications
    Language English
    Publishing date 2021-06-22
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/keab489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Challenges in Pulmonary Hypertension.

    Marra, Alberto M / Sherman, Alexander E / Ameri, Pietro / Bossone, Eduardo

    Heart failure clinics

    2022  Volume 19, Issue 1, Page(s) xv–xvi

    MeSH term(s) Humans ; Hypertension, Pulmonary/therapy
    Language English
    Publishing date 2022-11-27
    Publishing country United States
    Document type Editorial
    ZDB-ID 2212019-1
    ISSN 1551-7136
    ISSN 1551-7136
    DOI 10.1016/j.hfc.2022.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The COVID-19 pandemic as an opportunity to move healthcare system from hospital-centered care to patient-centered care: do black swans really exist?

    Delgado, Francesca / Lepre, Davide / Aliberti, Ludovica / Marra, Alberto M / Cittadini, Antonio

    Internal and emergency medicine

    2022  Volume 17, Issue 5, Page(s) 1263–1265

    MeSH term(s) COVID-19 ; Delivery of Health Care ; Hospitals ; Humans ; Pandemics ; Patient-Centered Care
    Language English
    Publishing date 2022-06-11
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-022-03009-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Assessment of pulmonary vascular response to exercise with Doppler-echocardiography: state of the art?

    Marra, Alberto M / Grünig, Ekkehard

    Journal of thoracic disease

    2017  Volume 9, Issue 10, Page(s) 3607–3608

    Language English
    Publishing date 2017-12-18
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2017.09.45
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Long-Term Follow-Up May be Useful in Coronavirus Disease 2019 Survivors to Prevent Chronic Complications.

    Cicco, Sebastiano / Vacca, Angelo / Cittadini, Antonio / Marra, Alberto M

    Infection & chemotherapy

    2020  Volume 52, Issue 3, Page(s) 407–409

    Keywords covid19
    Language English
    Publishing date 2020-07-21
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2020.52.3.407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cardiac rehabilitation and acute aortic dissection: understanding and addressing the evidence GAP a systematic review.

    Carbone, Andreina / Lamberti, Nicola / Manfredini, Roberto / Trimarchi, Santi / Palladino, Raffaele / Savriè, Caterina / Marra, Alberto M / Ranieri, Brigida / Crisci, Giulia / Izzo, Raffaele / Esposito, Giovanni / Cittadini, Antonio / Manfredini, Fabio / Rubenfire, Melvyn / Bossone, Eduardo

    Current problems in cardiology

    2024  Volume 49, Issue 3, Page(s) 102348

    Abstract: Despite guideline recommendations, strategies for implementing cardiac rehabilitation (CR) in patients with acute aortic dissection (AAD) are not well established with little evidence to risk stratify prudent and effective guidelines for the many ... ...

    Abstract Despite guideline recommendations, strategies for implementing cardiac rehabilitation (CR) in patients with acute aortic dissection (AAD) are not well established with little evidence to risk stratify prudent and effective guidelines for the many required variables. We conducted a systematic review of studies (2004-2023) reporting CR following type A (TA) and type B (TB) AAD. Our review is limited to open surgical repair for TA and medical treatment for TB. A total of 5 studies were included (4 TA-AAD and 1 TB-AAD) in the qualitative analysis. In general, observational data included 311 patients who had an overall favorable effect of CR in AAD consisting of a modestly improved exercise capacity and work load during cycle cardiopulmonary exercise test (TB-AAD), and improved quality of life (QoL). No adverse events were reported during symptom limited pre-CR treadmill or cycle exercise VO
    MeSH term(s) Humans ; Cardiac Rehabilitation ; Quality of Life ; Evidence Gaps ; Treatment Outcome ; Aortic Dissection/surgery ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2024-01-19
    Publishing country Netherlands
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2023.102348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Acute heart failure - an EFIM guideline critical appraisal and adaptation for internists.

    Kokorin, Valentin A / González-Franco, Alvaro / Cittadini, Antonio / Kalejs, Oskars / Larina, Vera N / Marra, Alberto M / Medrano, Francisco J / Monhart, Zdenek / Morbidoni, Laura / Pimenta, Joana / Lesniak, Wiktoria

    European journal of internal medicine

    2024  

    Abstract: Background: Over the past two decades, several studies have been conducted that have tried to answer questions on management of patients with acute heart failure (AHF) in terms of diagnosis and treatment. Updated international clinical practice ... ...

    Abstract Background: Over the past two decades, several studies have been conducted that have tried to answer questions on management of patients with acute heart failure (AHF) in terms of diagnosis and treatment. Updated international clinical practice guidelines (CPGs) have endorsed the findings of these studies. The aim of this document was to adapt recommendations of existing guidelines to help internists make decisions about specific and complex scenarios related to AHF.
    Methods: The adaptation procedure was to identify firstly unresolved clinical problems in patients with AHF in accordance with the PICO (Population, Intervention, Comparison and Outcomes) process, then conduct a critical assessment of existing CPGs and choose recommendations that are most applicable to these specific scenarios.
    Results: Seven PICOs were identified and CPGs were assessed. There is no single test that can help clinicians in discriminating patients with acute dyspnoea, congestion or hypoxaemia. Performing of echocardiography and natriuretic peptide evaluation is recommended, and chest X-ray and lung ultrasound may be considered. Treatment strategies to manage arterial hypotension and low cardiac output include short-term continuous intravenous inotropic support, vasopressors, renal replacement therapy, and temporary mechanical circulatory support. The most updated recommendations on how to treat specific patients with AHF and certain comorbidities and for reducing post-discharge rehospitalization and mortality are provided. Overall, 51 recommendations were endorsed and the rationale for the selection is provided in the main text.
    Conclusion: Through the use of appropriate tailoring process methodology, this document provides a simple and updated guide for internists dealing with AHF patients.
    Language English
    Publishing date 2024-03-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2024.02.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Long-Term Safety, Outcome, and Clinical Effects of Subcutaneous and Intravenous Treprostinil Treatment in Patients with Severe Chronic Pulmonary Arterial Hypertension.

    Harutyunova, Satenik / Benjamin, Nicola / Eichstaedt, Christina / Marra, Alberto M / Xanthouli, Panagiota / Nagel, Christian / Grünig, Ekkehard / Egenlauf, Benjamin

    Respiration; international review of thoracic diseases

    2023  Volume 102, Issue 8, Page(s) 579–590

    Abstract: Background: Current guidelines recommend treatment with parenteral prostacyclin analogs in patients with severe pulmonary arterial hypertension (PAH), who have insufficient response to treatment. Real-life data are sought to help physicians in treatment ...

    Abstract Background: Current guidelines recommend treatment with parenteral prostacyclin analogs in patients with severe pulmonary arterial hypertension (PAH), who have insufficient response to treatment. Real-life data are sought to help physicians in treatment decisions and clinical care of patients.
    Objective: This study analyzed safety, clinical effects, and long-term outcomes of subcutaneous (sc) and/or intravenous (iv) treprostinil via different pump systems in consecutive patients with PAH.
    Methods: Thirty-seven patients with severe progressive PAH despite dual combination therapy (20 female, mean age: 52.3 ± 15 years, mean pulmonary vascular resistance: 12.1 ± 5.1 WU) were initiated with add-on treprostinil sc and were routinely clinically assessed. Changes in clinical parameters, adverse events, and outcome were analyzed retrospectively.
    Results: In 24 of 37 patients, treprostinil administration was continued iv via implantation of LENUS Pro® pump after 3 ± 1.3 months, 6 patients continued with sc therapy, and 7 discontinued treatment. After 3, 6, 9, and 12 months of treprostinil treatment, patients showed a significant improvement in mean 6-min walk distance and tricuspid annular plane systolic excursion compared to baseline. In 8 of the 24 patients, iv pumps required surgical revision. During a mean follow-up of 2.82 ± 1.95 years, 12 patients died, four received lung transplantation. Transplant-free survival after 1, 2, and 3 years was 85.7%, 69.2%, and 65.3%, respectively.
    Conclusion: sc treprostinil as add-on to double combination treatment significantly improved exercise capacity and right heart function. In most patients, treprostinil could be continued via more tolerable iv administration approach (LENUS Pro® pump), showing reasonable overall survival with respect to the severity of PAH.
    MeSH term(s) Humans ; Female ; Adult ; Middle Aged ; Aged ; Pulmonary Arterial Hypertension/drug therapy ; Antihypertensive Agents/adverse effects ; Retrospective Studies ; Treatment Outcome ; Epoprostenol ; Hypertension, Pulmonary ; Familial Primary Pulmonary Hypertension
    Chemical Substances treprostinil (RUM6K67ESG) ; Antihypertensive Agents ; Epoprostenol (DCR9Z582X0)
    Language English
    Publishing date 2023-08-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 206674-9
    ISSN 1423-0356 ; 0025-7931
    ISSN (online) 1423-0356
    ISSN 0025-7931
    DOI 10.1159/000531169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The current evidence on prognostic factors in metastatic castration-resistant prostate cancer patients treated with Radium-223.

    Maggi, Martina / Gandaglia, Giorgio / Rajwa, Pawel / Martini, Alberto / Marra, Giancarlo

    Minerva urology and nephrology

    2023  Volume 74, Issue 6, Page(s) 791–793

    MeSH term(s) Male ; Humans ; Prostatic Neoplasms, Castration-Resistant/radiotherapy ; Prostatic Neoplasms, Castration-Resistant/pathology ; Prognosis ; Radium/therapeutic use
    Chemical Substances Radium-223 (8BR2SOL3L1) ; Radium (W90AYD6R3Q)
    Language English
    Publishing date 2023-01-05
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062840-4
    ISSN 2724-6442
    ISSN (online) 2724-6442
    DOI 10.23736/S2724-6051.22.05183-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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