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Article ; Online: Bioelectrical impedance analysis-derived phase angle (PhA) in lung cancer patients: a systematic review.

Prete, Melania / Ballarin, Giada / Porciello, Giuseppe / Arianna, Aniello / Luongo, Assunta / Belli, Valentina / Scalfi, Luca / Celentano, Egidio

BMC cancer

2024 Volume 24, Issue 1, Page(s) 608

Abstract: Background: Lung cancer is the second most diagnosed cancer in the world. Up to 84% of diagnosed patients have malnutrition, which can negatively affect quality of life and survival and may worsen with neoadjuvant treatment. Bioelectrical Impedance ... ...

Abstract	Background: Lung cancer is the second most diagnosed cancer in the world. Up to 84% of diagnosed patients have malnutrition, which can negatively affect quality of life and survival and may worsen with neoadjuvant treatment. Bioelectrical Impedance Analysis-Derived Phase Angle (PhA) in these patients could be a valid tool to assess the nutritional status in order to improve their condition. Methods: This review provides an update on PhA assessment in lung cancer patients over the past twenty years. We searched PubMed, Embase, Scopus, Web of Science, and Cochrane, for articles regarding the PhA obtained from Bioelectrical Impedance Analysis in lung cancer patients. The authors independently performed a literature search: sample size, patient population, study type, study dates, survival and interventions were evaluated. The final review included 11 studies from different countries. Results: Eight studies only considered patients with lung cancer, while three studies considered patients with different kind of cancer, including lung. Correlation data between PhA and age are conflicting. In patients undergoing clinical treatment and patients undergoing surgical treatment lower PhA was observed. A lower PhA is associated with a shorter survival. In three studies emerged a relationship between Karnofski Performance Status and Handgrip Strenght with PhA. From one study, univariate logistic regression analysis showed that higher PhA values represent a protective factor for sarcopenia. Conclusion: Our research underlined interesting, but not conclusive, results on this topic; however more researches are needed to understand the clinical meaning of PhA.
MeSH term(s)	Humans ; Electric Impedance ; Lung Neoplasms/pathology ; Nutritional Status ; Body Composition ; Quality of Life ; Malnutrition/diagnosis ; Malnutrition/etiology ; Male ; Female
Language	English
Publishing date	2024-05-20
Publishing country	England
Document type	Journal Article ; Systematic Review
ZDB-ID	2041352-X
ISSN	1471-2407 ; 1471-2407
ISSN (online)	1471-2407
ISSN	1471-2407
DOI	10.1186/s12885-024-12378-4
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Article ; Online: Complementary feeding approach and maternal responsiveness in 8- and 12-month-old Italian infants: A longitudinal study.

Di Prete, Alice / Del Grosso, Denise / Focaroli, Valentina / Paoletti, Melania / Pecora, Giulia / Hodges, Eric A / Galloway, Amy T / Farrow, Claire / Chiarotti, Flavia / Caravale, Barbara / Gasparini, Corinna / Gastaldi, Serena / Bellagamba, Francesca / Addessi, Elsa

Appetite

2023 Volume 190, Page(s) 107028

Abstract: In Western countries, infants are usually introduced to solids through spoon-fed puréed foods (parent-led weaning, PLW). However, an alternative approach known as "baby-led weaning" (BLW), in which infants usually participate in family meals and eat ... ...

Abstract	In Western countries, infants are usually introduced to solids through spoon-fed puréed foods (parent-led weaning, PLW). However, an alternative approach known as "baby-led weaning" (BLW), in which infants usually participate in family meals and eat independently, is becoming increasingly popular. We investigated the relationship between the type of complementary feeding approach and maternal responsiveness to infant feeding cues in a longitudinal sample of 178 infants observed at 8 and 12 months. Mothers reported the complementary feeding method used and, from video-recorded meals, we coded the proportion of time infants self-fed and rated maternal responsiveness by means of the Responsiveness to Child Feeding Cues Scale (Hodges et al., 2013). Responsiveness to infant receptiveness and fullness cues were significantly correlated at 8 months, but not at 12 months, when unresponsiveness decreased for receptiveness but remained stable for fullness cues. Thus, as infants got older, mothers were increasingly tuned in to their receptiveness cues. However, we did not observe the same pattern for fullness cues, perhaps because mothers were concerned that their infants did not eat enough. Moreover, at both time points, mothers were more responsive to infants' receptiveness than fullness cues, possibly due to an evolutionary drive to protect infants from starvation. Finally, responsiveness to fullness, but not responsiveness to receptiveness, was positively related to the proportion of infant self-feeding, but there were no significant differences in responsiveness depending on the self-reported complementary feeding approach. Thus, a weaning style that emphasizes independent feeding, regardless of whether this is labeled as BLW, may promote more infant-centered maternal responses at the end of the meal, with potential implications for promoting infant self-regulation not only at mealtimes, but also in other domains.
Language	English
Publishing date	2023-09-06
Publishing country	England
Document type	Journal Article
ZDB-ID	1461347-5
ISSN	1095-8304 ; 0195-6663
ISSN (online)	1095-8304
ISSN	0195-6663
DOI	10.1016/j.appet.2023.107028
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Article ; Online: Changes in Lifestyle and Dietary Habits during COVID-19 Lockdown in Italy: Results of an Online Survey.

Prete, Melania / Luzzetti, Anna / Augustin, Livia S A / Porciello, Giuseppe / Montagnese, Concetta / Calabrese, Ilaria / Ballarin, Giada / Coluccia, Sergio / Patel, Linia / Vitale, Sara / Palumbo, Elvira / Celentano, Egidio / La Vecchia, Carlo / Crispo, Anna

Nutrients

2021 Volume 13, Issue 6

Abstract: COVID-19 is an unprecedented global pandemic. On 12 March 2020, a lockdown order was issued in Italy in attempt to contain the health crisis. The study aimed to assess the impact of the COVID-19 lockdown on diet, physical activity, sleep quality, and ... ...

Abstract	COVID-19 is an unprecedented global pandemic. On 12 March 2020, a lockdown order was issued in Italy in attempt to contain the health crisis. The study aimed to assess the impact of the COVID-19 lockdown on diet, physical activity, sleep quality, and distress in an Italian cohort. An online anonymous interview, which included validated questionnaires was created to compare lifestyle habits pre- and during the lockdown. Data analysis from 604 subjects with a mean age of 29.8 years was carried out using multivariate analysis. Compared to pre-COVID-19 times, 67% of people changed their eating habits and increased consumption of foods containing added sugars. Women and men with low adherence to the Mediterranean Diet (MedDiet) were more likely to be physically inactive (
MeSH term(s)	Adult ; COVID-19 ; Communicable Disease Control ; Diet ; Diet, Mediterranean ; Exercise ; Feeding Behavior ; Female ; Health Behavior ; Humans ; Life Style ; Logistic Models ; Male ; Multivariate Analysis ; Pandemics ; Physical Distancing ; Psychological Distress ; SARS-CoV-2 ; Sedentary Behavior ; Surveys and Questionnaires ; Young Adult
Language	English
Publishing date	2021-06-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13061923
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Article: Changes in Lifestyle and Dietary Habits during COVID-19 Lockdown in Italy: Results of an Online Survey

Prete, Melania / Luzzetti, Anna / Augustin, Livia S. A. / Porciello, Giuseppe / Montagnese, Concetta / Calabrese, Ilaria / Ballarin, Giada / Coluccia, Sergio / Patel, Linia / Vitale, Sara / Palumbo, Elvira / Celentano, Egidio / La Vecchia, Carlo / Crispo, Anna

Nutrients. 2021 June 03, v. 13, no. 6

2021

Abstract	COVID-19 is an unprecedented global pandemic. On 12 March 2020, a lockdown order was issued in Italy in attempt to contain the health crisis. The study aimed to assess the impact of the COVID-19 lockdown on diet, physical activity, sleep quality, and distress in an Italian cohort. An online anonymous interview, which included validated questionnaires was created to compare lifestyle habits pre- and during the lockdown. Data analysis from 604 subjects with a mean age of 29.8 years was carried out using multivariate analysis. Compared to pre-COVID-19 times, 67% of people changed their eating habits and increased consumption of foods containing added sugars. Women and men with low adherence to the Mediterranean Diet (MedDiet) were more likely to be physically inactive (p < 0.0001 and p < 0.01, respectively). Results from logistic regression showed a three times higher risk of being inactive if adherence to the MedDiet was low (p < 0.0001), especially in men between 26 and 35 years. Lower levels of distress were reported in males who were physically active (89%) (p < 0.001). Our findings may help to identify effective lifestyle interventions during restrictive conditions.
Keywords	COVID-19 infection ; Mediterranean diet ; distress ; lifestyle ; pandemic ; physical activity ; regression analysis ; risk ; sleep ; surveys ; Italy
Language	English
Dates of publication	2021-0603
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13061923
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Article ; Online: One-year nutrition counselling in the context of a Mediterranean diet reduced the dietary inflammatory index in women with breast cancer: a role for the dietary glycemic index.

Vitale, Sara / Palumbo, Elvira / Polesel, Jerry / Hebert, James R / Shivappa, Nitin / Montagnese, Concetta / Porciello, Giuseppe / Calabrese, Ilaria / Luongo, Assunta / Prete, Melania / Pica, Rosa / Grimaldi, Maria / Crispo, Anna / Esindi, Nadia / Falzone, Luca / Mattioli, Veronica / Martinuzzo, Valentina / Poletto, Luigina / Cubisino, Serena /

Dainotta, Patrizia / De Laurentiis, Michelino / Pacilio, Carmen / Rinaldo, Massimo / Thomas, Guglielmo / D'Aiuto, Massimiliano / Serraino, Diego / Massarut, Samuele / Ferraù, Francesco / Rossello, Rosalba / Catalano, Francesca / Banna, Giuseppe L / Messina, Francesco / Gatti, Davide / Riccardi, Gabriele / Libra, Massimo / Celentano, Egidio / Jenkins, David J A / Augustin, Livia S A

Food & function

2023 Volume 14, Issue 3, Page(s) 1560–1572

Abstract: ... ...

Abstract	Background
MeSH term(s)	Humans ; Female ; Diet, Mediterranean ; Glycemic Index ; Breast Neoplasms ; Diet ; Inflammation/complications ; Carbohydrates
Chemical Substances	Carbohydrates
Language	English
Publishing date	2023-02-06
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2612033-1
ISSN	2042-650X ; 2042-6496
ISSN (online)	2042-650X
ISSN	2042-6496
DOI	10.1039/d2fo02198f
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Article: Strategies to evaluate outcomes in long-COVID-19 and post-COVID survivors.

Crispo, Anna / Bimonte, Sabrina / Porciello, Giuseppe / Forte, Cira Antonietta / Cuomo, Gaia / Montagnese, Concetta / Prete, Melania / Grimaldi, Maria / Celentano, Egidio / Amore, Alfonso / de Blasio, Elvio / Pentimalli, Francesca / Giordano, Antonio / Botti, Gerardo / Baglio, Giovanni / Sileri, Pierpaolo / Cascella, Marco / Cuomo, Arturo

Infectious agents and cancer

2021 Volume 16, Issue 1, Page(s) 62

Abstract: SARS-CoV-2 infection can impact the physical, cognitive, mental health of patients, especially in those recovered in intensive care units. Moreover, it was proved that the effects of the virus may persist for weeks or months. The term long-COVID or post- ... ...

Abstract	SARS-CoV-2 infection can impact the physical, cognitive, mental health of patients, especially in those recovered in intensive care units. Moreover, it was proved that the effects of the virus may persist for weeks or months. The term long-COVID or post-COVID syndrome is commonly used for indicating a variety of physical and psychological symptoms that continue after the resolution of the acute phase. This narrative review is aimed at providing an updated overview of the impact of physical, cognitive, and psychological health disorders in COVID-19 survivors, by summarizing the data already published in literature in the last year. Studies cited were found through PubMed searches. We also presented an overview of the post-COVID-19 health consequences on three important aspects: nutritional status, neurological disorders, and physical health. Moreover, to activate a correct health planning policy, a multidisciplinary approach for addressing the post- COVID-19 issue, has been proposed. Finally, the involvement of health professionals is necessary even after the pandemic, to reduce expected post-pandemic psychosocial responses and mental health disorders.
Language	English
Publishing date	2021-10-30
Publishing country	England
Document type	Journal Article
ISSN	1750-9378
ISSN	1750-9378
DOI	10.1186/s13027-021-00401-3
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Article ; Online: Combined addition of superoxide dismutase, catalase and glutathione peroxidase improves quality of cooled stored stallion semen.

Del Prete, Chiara / Stout, Tom / Montagnaro, Serena / Pagnini, Ugo / Uccello, Melania / Florio, Pasquale / Ciani, Francesca / Tafuri, Simona / Palumbo, Veronica / Pasolini, Maria Pia / Cocchia, Natascia / Henning, Heiko

Animal reproduction science

2019 Volume 210, Page(s) 106195

Abstract: During cold storage stallion spermatozoa experience undergo oxidative stress, which can impair sperm function and fertilizing capacity. Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) are the main endogenous enzymatic ... ...

Abstract	During cold storage stallion spermatozoa experience undergo oxidative stress, which can impair sperm function and fertilizing capacity. Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) are the main endogenous enzymatic antioxidants in stallion seminal plasma, and counteract reactive oxygen species. Semen dilution reduces the endogenous antioxidant concentrations. The aim of this study was to investigate whether addition of 15 IU/mL each of SOD, CAT, and GPX to diluted stallion semen would ameliorate a reactive oxygen-mediated decrease in semen quality during 72 h of storage at 5 °C. Ejaculates (n = 7) were divided in two aliquots and diluted in INRA 96 without (control) or with addition of antioxidants. Semen analysis was performed at the time of dilution and every 24 h during chilled storage. Antioxidant supplementation completely inhibited the storage-dependent increase in activated caspase 3 (P < 0.05). Concomitantly, the antioxidant-supplemented samples had a greater percentage of viable, motile and rapidly moving sperm than control samples after 72 h storage (P < 0.05). The DNA damage, as evaluated by TUNEL assay and SCSA, increased with storage time (P < 0.05). Antioxidant supplementation did not prevent, but did significantly reduce the increase in DNA strand breakage. The results indicate part of the intrinsic apoptotic pathway leading to effector caspase activation was inhibited, although an activation of molecules with endonuclease activity still occurred. In conclusion, adding equal concentrations of SOD, CAT and GPX to a semen extender suppressed caspase-3 activation and improved preservation of stallion sperm motility and viability during 72 h of storage at 5 °C.
MeSH term(s)	Animals ; Catalase/administration & dosage ; Catalase/pharmacology ; Glutathione Peroxidase/administration & dosage ; Glutathione Peroxidase/pharmacology ; Horses/physiology ; Male ; Semen/drug effects ; Semen Analysis/veterinary ; Semen Preservation/veterinary ; Sperm Motility ; Spermatozoa/physiology ; Superoxide Dismutase/administration & dosage ; Superoxide Dismutase/pharmacology
Chemical Substances	Catalase (EC 1.11.1.6) ; Glutathione Peroxidase (EC 1.11.1.9) ; Superoxide Dismutase (EC 1.15.1.1)
Language	English
Publishing date	2019-09-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	429674-6
ISSN	1873-2232 ; 0378-4320
ISSN (online)	1873-2232
ISSN	0378-4320
DOI	10.1016/j.anireprosci.2019.106195
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Article: Combined addition of superoxide dismutase, catalase and glutathione peroxidase improves quality of cooled stored stallion semen

Del Prete, Chiara / Ciani, Francesca / Cocchia, Natascia / Florio, Pasquale / Henning, Heiko / Montagnaro, Serena / Pagnini, Ugo / Palumbo, Veronica / Pasolini, Maria Pia / Stout, Tom / Tafuri, Simona / Uccello, Melania

Animal reproduction science. 2019 Sept. 21,

2019

Abstract	During cold storage stallion spermatozoa experience undergo oxidative stress, which can impair sperm function and fertilizing capacity. Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) are the main endogenous enzymatic antioxidants in stallion seminal plasma, and counteract reactive oxygen species. Semen dilution reduces the endogenous antioxidant concentrations. The aim of this study was to investigate whether addition of 15 IU/mL each of SOD, CAT, and GPX to diluted stallion semen would ameliorate a reactive oxygen-mediated decrease in semen quality during 72 hours of storage at 5 °C. Ejaculates (n = 7) were divided in two aliquots and diluted in INRA 96 without (control) or with addition of antioxidants. Semen analysis was performed at the time of dilution and every 24 hours during chilled storage. Antioxidant supplementation completely inhibited the storage-dependent increase in activated caspase 3 (P < 0.05). Concomitantly, the antioxidant-supplemented samples had a greater percentage of viable, motile and rapidly moving sperm than control samples after 72 hours storage (P < 0.05). The DNA damage, as evaluated by TUNEL assay and SCSA, increased with storage time (P < 0.05). Antioxidant supplementation did not prevent, but did significantly reduce the increase in DNA strand breakage. The results indicate part of the intrinsic apoptotic pathway leading to effector caspase activation was inhibited, although an activation of molecules with endonuclease activity still occurred. In conclusion, adding equal concentrations of SOD, CAT and GPX to a semen extender suppressed caspase-3 activation and improved preservation of stallion sperm motility and viability during 72 h of storage at 5 °C.
Keywords	apoptosis ; caspase-3 ; catalase ; cold storage ; DNA ; DNA damage ; enzyme activity ; glutathione peroxidase ; oxidative stress ; reactive oxygen species ; semen extenders ; semen quality ; seminal plasma ; sperm motility ; spermatozoa ; stallions ; storage temperature ; storage time ; superoxide dismutase ; viability
Language	English
Dates of publication	2019-0921
Publishing place	Elsevier B.V.
Document type	Article
Note	Pre-press version
ZDB-ID	429674-6
ISSN	1873-2232 ; 0378-4320
ISSN (online)	1873-2232
ISSN	0378-4320
DOI	10.1016/j.anireprosci.2019.106195
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: A new sensitive and accurate model to predict moderate to severe obstructive sleep apnea in patients with obesity.

Ahlin, Sofie / Manco, Melania / Panunzi, Simona / Verrastro, Ornella / Giannetti, Giulia / Prete, Anna / Guidone, Caterina / Berardino, Alessandro Di Marco / Viglietta, Luca / Ferravante, Anna / Mingrone, Geltrude / Mormile, Flaminio / Capristo, Esmeralda

Medicine

2019 Volume 98, Issue 32, Page(s) e16687

Abstract: Obstructive sleep apnea (OSA) has a high prevalence in patients with obesity. Only patients with clinical symptoms of OSA are admitted to polysomnography; however, many patients with OSA are asymptomatic. We aimed to create and validate a population- ... ...

Abstract	Obstructive sleep apnea (OSA) has a high prevalence in patients with obesity. Only patients with clinical symptoms of OSA are admitted to polysomnography; however, many patients with OSA are asymptomatic. We aimed to create and validate a population-based risk score that predicts the severity of OSA in patients with obesity.We here report the cross-sectional analysis at baseline of an ongoing study investigating the long-term effect of bariatric surgery on OSA. One-hundred sixty-one patients of the Obesity Center of the Catholic University Hospital in Rome, Italy were included in the study. The patients underwent overnight cardiorespiratory monitoring, blood chemistry analyses, hepatic ultrasound, and anthropometric measurements. The patients were divided into 2 groups according OSA severity assessed by the apnea-hypopnea index (AHI): AHI < 15 = no or mild and AHI ≥ 15 moderate to severe OSA. A statistical prediction model was created and validated. C statistics was used to evaluate the discrimination performance of the model.The prevalence of OSA was 96.3% with 74.5% of the subjects having moderate/severe OSA. Sex, body mass index, diabetes, and age were included in the final prediction model that had excellent discrimination ability (C statistics equals to 83%). An OSA risk chart score for clinical use was created.Patients with severe obesity are at a very high risk for moderate or severe OSA in particular if they are men, older, more obese, and/or with type 2 diabetes. The OSA risk chart can be useful for general practitioners and patients as well as for bariatric surgeons to select patients with high risk of moderate to severe OSA for further polysomnography.
MeSH term(s)	Adult ; Age Factors ; Body Mass Index ; Cross-Sectional Studies ; Diabetes Mellitus/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Models, Statistical ; Obesity, Morbid/epidemiology ; Obesity, Morbid/physiopathology ; Prevalence ; ROC Curve ; Regression Analysis ; Risk Factors ; Sensitivity and Specificity ; Severity of Illness Index ; Sex Factors ; Sleep Apnea, Obstructive/diagnosis ; Sleep Apnea, Obstructive/epidemiology
Language	English
Publishing date	2019-08-14
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000016687
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Article ; Online: Correction: Mediterranean diet and quality of life in women treated for breast cancer: A baseline analysis of DEDiCa multicentre trial.

Porciello, Giuseppe / Montagnese, Concetta / Crispo, Anna / Grimaldi, Maria / Libra, Massimo / Vitale, Sara / Palumbo, Elvira / Pica, Rosa / Calabrese, Ilaria / Cubisino, Serena / Falzone, Luca / Poletto, Luigina / Martinuzzo, Valentina / Prete, Melania / Esindi, Nadia / Thomas, Guglielmo / Cianniello, Daniela / Pinto, Monica / De Laurentiis, Michelino /

Pacilio, Carmen / Rinaldo, Massimo / D'Aiuto, Massimiliano / Serraino, Diego / Massarut, Samuele / Evangelista, Chiara / Steffan, Agostino / Catalano, Francesca / Banna, Giuseppe L / Scandurra, Giuseppa / Ferraù, Francesco / Rossello, Rosalba / Antonelli, Giovanna / Guerra, Gennaro / Farina, Amalia / Messina, Francesco / Riccardi, Gabriele / Gatti, Davide / Jenkins, David J A / Minopoli, Anita / Grilli, Bruna / Cavalcanti, Ernesta / Celentano, Egidio / Botti, Gerardo / Montella, Maurizio / Augustin, Livia S A

PloS one

2021 Volume 16, Issue 8, Page(s) e0256944

Abstract: This corrects the article DOI: 10.1371/journal.pone.0239803.]. ...

Abstract	[This corrects the article DOI: 10.1371/journal.pone.0239803.].
Language	English
Publishing date	2021-08-26
Publishing country	United States
Document type	Published Erratum
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0256944
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