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  1. Book ; Thesis: The GAPDH redox switch

    Rechmann, Benedikt / Dick, Tobias P. / Teleman, Aurelio A.

    a guardian of cellular reductive capacity that promotes tumor growth and limits efficiency of pro-oxidative tumor therapies

    2020  

    Institution Universität Heidelberg
    Author's details presented by Benedikt Rechmann, M.Sc. ; first referee: Privatdozent Dr. Tobias P. Dick, second referee: Professor Dr. Aurelio Teleman
    Language English ; German
    Size XIX, 118 Seiten, Diagramme, Illustrationen
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruperto Carola University Heidelberg, 2020
    Note Text in Englisch, Zusammenfassung in deutscher und englischer Sprache
    HBZ-ID HT021003415
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Electricity Price, Heat and Risk of Climate Poverty in Spain's Current Climate Change Scenario.

    Tobías, Aurelio

    The Lancet regional health. Europe

    2021  Volume 11, Page(s) 100271

    Language English
    Publishing date 2021-11-20
    Publishing country England
    Document type Journal Article
    ISSN 2666-7762
    ISSN (online) 2666-7762
    DOI 10.1016/j.lanepe.2021.100271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Electricity price, heat and risk of climate poverty in spain's current climate change scenario

    Aurelio Tobías

    The Lancet Regional Health. Europe, Vol 11, Iss , Pp 100271- (2021)

    2021  

    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Evaluation of the lockdowns for the SARS-CoV-2 epidemic in Italy and Spain after one month follow up.

    Tobías, Aurelio

    The Science of the total environment

    2020  Volume 725, Page(s) 138539

    Abstract: From the end of February, the SARS-CoV-2 epidemic in Spain has been following the footsteps of that in Italy very closely. We have analyzed the trends of incident cases, deaths, and intensive care unit admissions (ICU) in both countries before and after ... ...

    Abstract From the end of February, the SARS-CoV-2 epidemic in Spain has been following the footsteps of that in Italy very closely. We have analyzed the trends of incident cases, deaths, and intensive care unit admissions (ICU) in both countries before and after their respective national lockdowns using an interrupted time-series design. Data was analyzed with quasi-Poisson regression using an interaction model to estimate the change in trends. After the first lockdown, incidence trends were considerably reduced in both countries. However, although the slopes have been flattened for all outcomes, the trends kept rising. During the second lockdown, implementing more restrictive measures for mobility, it has been a change in the trend slopes for both countries in daily incident cases and ICUs. This improvement indicates that the efforts overtaken are being successful in flattening the epidemic curve, and reinforcing the belief that we must hold on.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Follow-Up Studies ; Humans ; Italy ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Spain
    Keywords covid19
    Language English
    Publishing date 2020-04-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2020.138539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Evaluation of the lockdowns for the SARS-CoV-2 epidemic in Italy and Spain after one month follow up

    Tobías, Aurelio

    Science of The Total Environment

    2020  Volume 725, Page(s) 138539

    Keywords Environmental Engineering ; Waste Management and Disposal ; Pollution ; Environmental Chemistry ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2020.138539
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Time-stratified case-crossover studies for aggregated data in environmental epidemiology: a tutorial.

    Tobias, Aurelio / Kim, Yoonhee / Madaniyazi, Lina

    International journal of epidemiology

    2024  Volume 53, Issue 2

    Abstract: The case-crossover design is widely used in environmental epidemiology as an effective alternative to the conventional time-series regression design to estimate short-term associations of environmental exposures with a range of acute events. This ... ...

    Abstract The case-crossover design is widely used in environmental epidemiology as an effective alternative to the conventional time-series regression design to estimate short-term associations of environmental exposures with a range of acute events. This tutorial illustrates the implementation of the time-stratified case-crossover design to study aggregated health outcomes and environmental exposures, such as particulate matter air pollution, focusing on adjusting covariates and investigating effect modification using conditional Poisson regression. Time-varying confounders can be adjusted directly in the conditional regression model accounting for the adequate lagged exposure-response function. Time-invariant covariates at the subpopulation level require reshaping the typical time-series data set into a long format and conditioning out the covariate in the expanded stratum set. When environmental exposure data are available at geographical units, the stratum set should combine time and spatial dimensions. Moreover, it is possible to examine effect modification using interaction models. The time-stratified case-crossover design offers a flexible framework to properly account for a wide range of covariates in environmental epidemiology studies.
    MeSH term(s) Humans ; Cross-Over Studies ; Air Pollution/adverse effects ; Environmental Exposure/adverse effects ; Environmental Exposure/analysis ; Particulate Matter ; Time Factors
    Chemical Substances Particulate Matter
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 187909-1
    ISSN 1464-3685 ; 0300-5771
    ISSN (online) 1464-3685
    ISSN 0300-5771
    DOI 10.1093/ije/dyae020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Heat-attributable Mortality in the Summer of 2022 in Spain.

    Tobías, Aurelio / Royé, Dominic / Iñiguez, Carmen

    Epidemiology (Cambridge, Mass.)

    2022  Volume 34, Issue 2, Page(s) e5–e6

    MeSH term(s) Humans ; Hot Temperature ; Spain/epidemiology ; Seasons ; Climate Change ; Mortality
    Language English
    Publishing date 2022-12-20
    Publishing country United States
    Document type Letter
    ZDB-ID 1053263-8
    ISSN 1531-5487 ; 1044-3983
    ISSN (online) 1531-5487
    ISSN 1044-3983
    DOI 10.1097/EDE.0000000000001583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Evaluation of the lockdowns for the SARS-CoV-2 epidemic in Italy and Spain after one month follow up

    Tobías, Aurelio

    Sci Total Environ

    Abstract: From the end of February, the SARS-CoV-2 epidemic in Spain has been following the footsteps of that in Italy very closely. We have analyzed the trends of incident cases, deaths, and intensive care unit admissions (ICU) in both countries before and after ... ...

    Abstract From the end of February, the SARS-CoV-2 epidemic in Spain has been following the footsteps of that in Italy very closely. We have analyzed the trends of incident cases, deaths, and intensive care unit admissions (ICU) in both countries before and after their respective national lockdowns using an interrupted time-series design. Data was analyzed with quasi-Poisson regression using an interaction model to estimate the change in trends. After the first lockdown, incidence trends were considerably reduced in both countries. However, although the slopes have been flattened for all outcomes, the trends kept rising. During the second lockdown, implementing more restrictive measures for mobility, it has been a change in the trend slopes for both countries in daily incident cases and ICUs. This improvement indicates that the efforts overtaken are being successful in flattening the epidemic curve, and reinforcing the belief that we must hold on.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #34808
    Database COVID19

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  9. Article ; Online: Evaluation of the lockdowns for the SARS-CoV-2 epidemic in Italy and Spain after one month follow up

    Tobías, Aurelio

    2020  

    Abstract: From the end of February, the SARS-CoV-2 epidemic in Spain has been following the footsteps of that in Italy very closely. We have analyzed the trends of incident cases, deaths, and intensive care unit admissions (ICU) in both countries before and after ... ...

    Abstract From the end of February, the SARS-CoV-2 epidemic in Spain has been following the footsteps of that in Italy very closely. We have analyzed the trends of incident cases, deaths, and intensive care unit admissions (ICU) in both countries before and after their respective national lockdowns using an interrupted time-series design. Data was analyzed with quasi-Poisson regression using an interaction model to estimate the change in trends. After the first lockdown, incidence trends were considerably reduced in both countries. However, although the slopes have been flattened for all outcomes, the trends kept rising. During the second lockdown, implementing more restrictive measures for mobility, it has been a change in the trend slopes for both countries in daily incident cases and ICUs. This improvement indicates that the efforts overtaken are being successful in flattening the epidemic curve, and reinforcing the belief that we must hold on.

    Peer reviewed
    Keywords SARS-CoV-2 ; Lockdown ; Interrupted time-series ; Mortality ; Intensive care unit admissions ; covid19
    Language English
    Publishing date 2020-04-06
    Publisher Elsevier BV
    Publishing country es
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Evaluation of the lockdowns for the SARS-CoV-2 epidemic in Italy and Spain after one month follow up

    Tobías, Aurelio

    Science of the total environment. 2020 July 10, v. 725

    2020  

    Abstract: From the end of February, the SARS-CoV-2 epidemic in Spain has been following the footsteps of that in Italy very closely. We have analyzed the trends of incident cases, deaths, and intensive care unit admissions (ICU) in both countries before and after ... ...

    Abstract From the end of February, the SARS-CoV-2 epidemic in Spain has been following the footsteps of that in Italy very closely. We have analyzed the trends of incident cases, deaths, and intensive care unit admissions (ICU) in both countries before and after their respective national lockdowns using an interrupted time-series design. Data was analyzed with quasi-Poisson regression using an interaction model to estimate the change in trends. After the first lockdown, incidence trends were considerably reduced in both countries. However, although the slopes have been flattened for all outcomes, the trends kept rising. During the second lockdown, implementing more restrictive measures for mobility, it has been a change in the trend slopes for both countries in daily incident cases and ICUs. This improvement indicates that the efforts overtaken are being successful in flattening the epidemic curve, and reinforcing the belief that we must hold on.
    Keywords models ; time series analysis ; Italy ; Spain ; covid19
    Language English
    Dates of publication 2020-0710
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2020.138539
    Database NAL-Catalogue (AGRICOLA)

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