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  1. Book ; Thesis: Prevention and reversal of neuronal sensitization in the spinal cord by blocking spinal glial cell activation in an animal model of non-specific chronic low back pain

    Zhang, Juanjuan

    2016  

    Author's details vorgelegt von Juanjuan Zhang
    Language English
    Size 160 Blätter, Illustrationen, Diagramme
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2016
    HBZ-ID HT019176321
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 E 1857 order for loan Magazin

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  2. Article ; Online: Combined treatment of peripheral facial-nerve palsy secondary to cerebral pontine hemorrhage: A case report and literature review.

    Zhang, Juanjuan / Sun, Shaoxia / Feng, Haixia / Li, Yabin

    Asian journal of surgery

    2024  Volume 47, Issue 5, Page(s) 2451–2452

    MeSH term(s) Humans ; Facial Paralysis/etiology ; Pons/blood supply ; Pons/diagnostic imaging ; Cerebral Hemorrhage/etiology ; Cerebral Hemorrhage/complications ; Cerebral Hemorrhage/diagnostic imaging ; Cerebral Hemorrhage/surgery ; Male ; Female ; Combined Modality Therapy ; Middle Aged ; Facial Nerve Diseases/etiology
    Language English
    Publishing date 2024-01-29
    Publishing country Netherlands
    Document type Case Reports ; Letter ; Review
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.01.113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2831: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Correction to: A Chinese Family with Digenic TBP/STUB1 Spinocerebellar Ataxia.

    Liu, Lili / Chen, Juanjuan / Zhang, Guogao / Lin, Zhijian / Chen, Di / Hu, Jun

    Cerebellum (London, England)

    2024  

    Language English
    Publishing date 2024-02-24
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2112586-7
    ISSN 1473-4230 ; 1473-4222
    ISSN (online) 1473-4230
    ISSN 1473-4222
    DOI 10.1007/s12311-024-01672-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5795: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Comparison of biomechanical analysis results using different musculoskeletal models for children with cerebral palsy.

    Jing, Zhibo / Han, Jianda / Zhang, Juanjuan

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1217918

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-09-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1217918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Copper and Palladium Cocatalyzed Defluorinative Coupling of

    Liu, Xinyu / Wu, Juanjuan / Zhang, Chun

    Organic letters

    2023  Volume 25, Issue 9, Page(s) 1564–1568

    Abstract: A novel copper and palladium cocatalyzed defluorinative coupling ... ...

    Abstract A novel copper and palladium cocatalyzed defluorinative coupling of
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c00347
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

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  6. Article: Editorial: Microorganisms and their derivatives for cancer therapy.

    Zhang, Yunlei / Rodrigues, Lígia R / Cao, Zhenping / Li, Juanjuan

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1137341

    Language English
    Publishing date 2023-01-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1137341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Brigatinib combined with cetuximab in the fifth-line treatment of non-small cell lung cancer with EGFR p.C797S mutation in critically ill patients: a report of two cases and literature review.

    Liu, Juanjuan / Lei, Hongtao / Zhang, Ding / Zhang, Ning

    Anti-cancer drugs

    2024  

    Abstract: For critically ill patients with non-small cell lung cancer (NSCLC) in need of life-saving treatment, there is currently no reported evidence regarding the use of medication specifically targeting epidermal growth factor receptor (EGFR) p.C797S mutation, ...

    Abstract For critically ill patients with non-small cell lung cancer (NSCLC) in need of life-saving treatment, there is currently no reported evidence regarding the use of medication specifically targeting epidermal growth factor receptor (EGFR) p.C797S mutation, which is known to cause resistance to third-generation tyrosine kinase inhibitors (TKIs). Our report aims to investigate and explore treatment strategies to overcome resistance associated with EGFR p.C797S mutation in order to provide potential therapeutic options for these patients. Here, we reported two cases with NSCLC who initially harbored an EGFR-sensitive mutation and were both treated with osimertinib, a third-generation TKI. Next-generation sequencing tests conducted prior to the initiation of fifth-line therapy in critically ill patients revealed the presence of EGFR p.C797S mutations in both patients, suggesting acquired resistance. In the course of fifth-line therapy, the administration of a combination of brigatinib and cetuximab proved vital in saving critically ill patients, moderately extending their overall survival period. Our findings suggested that a combined regimen of brigatinib and cetuximab could serve as a potentially life-saving therapeutic strategy for critically ill patients with NSCLC, particularly those demonstrating EGFR p.C797S-mediated resistance. Further studies, however, are required to validate and expand upon these promising findings.
    Language English
    Publishing date 2024-03-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065301-6
    ISSN 1473-5741 ; 0959-4973
    ISSN (online) 1473-5741
    ISSN 0959-4973
    DOI 10.1097/CAD.0000000000001598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3125: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Teneligliptin alleviates diabetes-related cognitive impairment by inhibiting the endoplasmic reticulum (ER) stress and NLRP3 inflammasome in mice.

    Wang, Weifeng / Zhang, Juanjuan

    Aging

    2023  Volume 15

    Abstract: Diabetes mellitus (DM) significantly influences the normal health of patients with its severe complications, including diabetes-related cognitive impairment (CI). Recently, neuroinflammation and oxidative stress (OS) have been reported to participate in ... ...

    Abstract Diabetes mellitus (DM) significantly influences the normal health of patients with its severe complications, including diabetes-related cognitive impairment (CI). Recently, neuroinflammation and oxidative stress (OS) have been reported to participate in the pathogenesis of diabetes-related CI. Teneligliptin, an inhibitor of DDP-IV, was developed for treating DM and is claimed with promising effects against inflammation. Herein, in the current study, we examined the potential therapeutic function of Teneligliptin against diabetes-related CI. Db/m or diabetic mice were orally administered with teneligliptin (60 mg/kg/day) for 10 weeks. Elevated levels of total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C), increased escape latency, declined time in the platform quadrant and decreased number of platform crossings in the Morris water maze test, reduced freezing index in the fear conditioning test, and lessened time spent in the novel arm and percentage of alterations in the Y-maze test were observed in diabetic mice, all of which were sharply improved by teneligliptin. Furthermore, increased levels of inflammatory cytokines and activated OS state were observed in the hippocampus of diabetic mice, which were markedly repressed by Teneligliptin. Lastly, the activation of the NOD-like receptor family pyrin domain containing 3 (NLRP3) signaling and the endoplasmic reticulum (ER) stress pathway in the hippocampus of diabetic mice were notably inhibited by teneligliptin. Collectively, teneligliptin mitigated diabetes-related CI by repressing the ER stress and NLRP3 inflammasome in diabetic mice.
    Language English
    Publishing date 2023-12-19
    Publishing country United States
    Document type Journal Article
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.205333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Fabrication of high quality lead-free double perovskite Cs

    Zhang, Xiaofang / Wang, Ke / Li, Zhenyu / Qi, Juanjuan / Li, Dongke / Luo, Jianqiang / Liu, Jian

    Nanotechnology

    2024  Volume 35, Issue 19

    Abstract: Recently, the lead-free double perovskite ... ...

    Abstract Recently, the lead-free double perovskite Cs
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ad2158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Prostate cancer burden in major BRICS countries, 1990-2019: findings from the 2019 global burden of disease study.

    Zhang, Juan / Ma, Juanjuan / Li, Shuting / Ma, Yan

    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)

    2024  

    Abstract: Background: This study assessed prostate cancer burden and trends in major BRICS countries (Brazil, Russia, India, China, and South Africa) from 1990 to 2019.: Methods: Utilizing Global Burden of Disease Study 2019 data, we calculated age- ... ...

    Abstract Background: This study assessed prostate cancer burden and trends in major BRICS countries (Brazil, Russia, India, China, and South Africa) from 1990 to 2019.
    Methods: Utilizing Global Burden of Disease Study 2019 data, we calculated age-standardized rates for prostate cancer incidence, prevalence, mortality, and disability-adjusted life years (DALYs) with 95% uncertainty intervals (UIs). Joinpoint regression analysis determined the average annual percentage change (AAPC) for trend characterization.
    Results: Prostate cancer ranked highest in China for incidence, prevalence, mortality, and DALYs. In 2019, Brazil had the highest age-standardized incidence rate (ASIR) [55.029 (95% UI: 47.744-81.831)] and age-standardized prevalence rate (ASPR) [372.511 (95% UI: 327.549-549.128)], while South Africa recorded the highest age-standardized mortality rate (ASMR) [42.241 (95% UI: 32.146-47.933)], and age-standardized DALY rate (ASDR) [666.085 (95% UI: 522.626-764.612)]. ASIR and ASPR increased significantly over three decades (AAPC > 0), with varying ASMR and ASDR trends.
    Conclusion: Prostate cancer poses a significant public health challenge. While incidence and prevalence rise, mortality declines in China, India, and Brazil. Tailored health policies are crucial to address diverse disease burden characteristics.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1137033-6
    ISSN 1473-5709 ; 0959-8278
    ISSN (online) 1473-5709
    ISSN 0959-8278
    DOI 10.1097/CEJ.0000000000000890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3621: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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