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  1. Article ; Online: Complete mitochondrial genome of the decomposer

    Jeong, Gilsang / Han, Areum / Kang, Hyejin / Jeong, Yeo Won / Jin, Seon Deok

    Mitochondrial DNA. Part B, Resources

    2023  Volume 8, Issue 3, Page(s) 375–378

    Abstract: Ptecticus ... ...

    Abstract Ptecticus tenebrifer
    Language English
    Publishing date 2023-03-10
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2023.2184659
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Sequential changes in intraocular pressure during strabismus surgery in patients with thyroid eye disease.

    Jeong, Areum / Kim, Won Jae

    BMC ophthalmology

    2022  Volume 22, Issue 1, Page(s) 128

    Abstract: Background/aims: To investigate the sequential change in intraocular pressure (IOP) during strabismus surgery in patients with thyroid eye disease (TED).: Methods: This prospective study included patients with TED who underwent strabismus surgery ( ... ...

    Abstract Background/aims: To investigate the sequential change in intraocular pressure (IOP) during strabismus surgery in patients with thyroid eye disease (TED).
    Methods: This prospective study included patients with TED who underwent strabismus surgery (medial rectus [MR], inferior rectus [IR], and superior rectus [SR] recession) between March 2018 and December 2020. The IOP was measured six times during surgery (5 min after intubation, after isolation of the muscle using a hook and dissection of the surrounding tissue, immediately before muscle detachment, immediately after muscle detachment, after reattachment of the muscle, and after closure of the conjunctiva).
    Results: Thirty-five eyes of 18 patients were included. The mean IOP at first was 21.1 mmHg, which significantly increased to 28.6 mmHg after muscle isolation. The IOP significantly decreased to 15.5 mmHg after muscle detachment. This increased to 19.1 mmHg after muscle reattachment. The last IOP was 18.9 mmHg. There were similar patterns of sequential change in the IOP among the three muscles. The MR showed the highest increase in IOP. The IR showed the lowest mean IOP compared with the other two muscles.
    Conclusions: The IOP was elevated during the isolation and dissection of the surrounding muscle tissue, especially in the MR. The IOP significantly decreased after muscle detachment and was maintained until the last measurement, even after muscle reattachment. IR showed the lowest IOP among the three muscles during surgery.
    MeSH term(s) Graves Ophthalmopathy/complications ; Graves Ophthalmopathy/surgery ; Humans ; Intraocular Pressure ; Oculomotor Muscles/surgery ; Prospective Studies ; Strabismus/surgery
    Language English
    Publishing date 2022-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050436-6
    ISSN 1471-2415 ; 1471-2415
    ISSN (online) 1471-2415
    ISSN 1471-2415
    DOI 10.1186/s12886-022-02352-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Changes in the Clinical Practice of Ophthalmology during the Coronavirus Disease 2019 (COVID-19) Outbreak: an Experience from Daegu, Korea.

    Jeong, Areum / Sagong, Min

    Infection & chemotherapy

    2020  Volume 52, Issue 2, Page(s) 226–230

    Keywords covid19
    Language English
    Publishing date 2020-06-02
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2020.52.2.226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Synthesis of 1

    Park, Areum / Jeong, Kyu-Sung / Lee, Hyuk / Kim, Hyunwoo

    ACS omega

    2021  Volume 6, Issue 9, Page(s) 6498–6508

    Abstract: We described a silver(I)-mediated intramolecular oxidative C-H amination that enables the construction of assorted ... ...

    Abstract We described a silver(I)-mediated intramolecular oxidative C-H amination that enables the construction of assorted 1
    Language English
    Publishing date 2021-02-23
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.1c00025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: MULTIMODAL IMAGING FEATURES AND TREATMENT RESPONSES OF CHOROIDAL NEOVASCULARIZATION SECONDARY TO CENTRAL SEROUS CHORIORETINOPATHY.

    Jeong, Areum / Kang, Wonki / Sagong, Min

    Retina (Philadelphia, Pa.)

    2022  Volume 42, Issue 12, Page(s) 2326–2335

    Abstract: Purpose: To investigate features of central serous chorioretinopathy with choroidal neovascularization (CNV) on multimodal imaging and analyze their association with treatment response.: Methods: A total of 37 patients with chronic central serous ... ...

    Abstract Purpose: To investigate features of central serous chorioretinopathy with choroidal neovascularization (CNV) on multimodal imaging and analyze their association with treatment response.
    Methods: A total of 37 patients with chronic central serous chorioretinopathy complicated by CNV were divided into bevacizumab and photodynamic therapy groups, and each group was subdivided into responders and nonresponders according to subretinal fluid status at 3 months. We assessed multimodal imaging parameters (subfoveal choroidal thickness; vortex vein engorgement; choroidal vascular hyperpermeability; and CNV morphologic pattern, area, and vessel density) and analyzed their association with treatment responses.
    Results: Responders in the bevacizumab group showed thinner subfoveal choroidal thickness (384.0 ± 103.2 vs. 398.3 ± 87.1 µm, P = 0.042), smaller CNV area (0.512 ± 0.267 vs. 1.323 ± 0.481 mm2, P = 0.007), open-circuit pattern (84.6% vs. 12.5%, P < 0.001), and capillary fringe (69.2% vs. 37.5%, P = 0.001) than nonresponders. Responders in the photodynamic therapy group had thicker subfoveal choroidal thickness (420.1 ± 93.5 vs. 395.7 ± 6.5 µm, P = 0.021), more quadrants with engorged vortex veins extending to the macula (P = 0.012), and intense choroidal vascular hyperpermeability (57.1% vs. 50.0%, P = 0.026) than nonresponders. Choroidal neovascularization showing closed-circuit pattern (85.7% vs. 0%, P = 0.001) and peripheral loop (64.3% vs. 0%, P = 0.001) demonstrated a good response to photodynamic therapy.
    Conclusion: Heterogeneous features of choroidal hyperpermeability, thickness, and CNV morphology in CNV accompanying central serous chorioretinopathy are associated with different therapeutic responses to bevacizumab and photodynamic therapy treatments.
    MeSH term(s) Humans ; Central Serous Chorioretinopathy/complications ; Central Serous Chorioretinopathy/diagnosis ; Central Serous Chorioretinopathy/drug therapy ; Choroidal Neovascularization/diagnosis ; Choroidal Neovascularization/drug therapy ; Choroidal Neovascularization/etiology ; Bevacizumab/therapeutic use ; Tomography, Optical Coherence ; Multimodal Imaging
    Chemical Substances Bevacizumab (2S9ZZM9Q9V)
    Language English
    Publishing date 2022-11-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000003615
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Synthesis of 1H‑Indazoles via Silver(I)-Mediated Intramolecular Oxidative C–H Bond Amination

    Areum Park / Kyu-Sung Jeong / Hyuk Lee / Hyunwoo Kim

    ACS Omega, Vol 6, Iss 9, Pp 6498-

    2021  Volume 6508

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Bias-corrected Hp(10)-to-Organ-Absorbed Dose Conversion Coefficients for the Epidemiological Study of Korean Radiation Workers.

    Jeong, Areum / Kwon, Tae-Eun / Lee, Wonho / Park, Sunhoo

    Journal of radiation protection and research

    2022  Volume 47, Issue 3, Page(s) 158–166

    Abstract: Background: The effects of radiation on the health of radiation workers who are constantly susceptible to occupational exposure must be assessed based on an accurate and reliable reconstruction of organ-absorbed doses that can be calculated using ... ...

    Abstract Background: The effects of radiation on the health of radiation workers who are constantly susceptible to occupational exposure must be assessed based on an accurate and reliable reconstruction of organ-absorbed doses that can be calculated using personal dosimeter readings measured as
    Materials and methods: Two major biases were considered: (1) the bias in
    Results and discussion: The bias in
    Conclusion: The obtained results will aid future studies in assessing the health effects of occupational exposure of Korean radiation workers. The bias-corrected dose coefficients of this study can be used to calculate organ doses for Korean radiation workers based personal dose records.
    Language English
    Publishing date 2022-09-30
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2466-2461
    ISSN (online) 2466-2461
    DOI 10.14407/jrpr.2022.00052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Clinical significance of metabolic quantification for retinal nonperfusion in diabetic retinopathy

    Areum Jeong / Xue Yao / Jano van Hemert / Min Sagong

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Volume 9

    Abstract: Abstract Diabetic retinopathy (DR) is characterized by microvascular changes including ischemia. Degradation and metabolic changes of various retinal cells occur during ischemia. Ischemic region containing more cells will lead to greater metabolic ... ...

    Abstract Abstract Diabetic retinopathy (DR) is characterized by microvascular changes including ischemia. Degradation and metabolic changes of various retinal cells occur during ischemia. Ischemic region containing more cells will lead to greater metabolic impairment. We analyzed the non-perfusion region (NPR) by integrating histologic mapping with ultra-widefield fluorescein angiography (UWF FA) images. We also investigated the correlations of the weighted ischemic index (ISI) considering the regional distribution of retinal cells with cytokines, macular edema (ME), and neovascularization (NV). In this study, 32 patients with treatment-naïve DR and 21 age-matched control participants were included. The difference between the non-weighted and weighted ISI of NPR with leakage was greatest at the posterior region. The weighted ISI of NPR with leakage was correlated with MCP-1, IL-8, IL-6, PlGF, and VEGF-A levels, while the non-weighted ISI of NPR with leakage was correlated with IL-8 and IL-6 levels. The presence of baseline ME or NV in patients with DR was associated with the weighted ISI, with a stronger association when cones and rods were weighted. The weighted ISI reflecting both metabolic activity and cell distribution demonstrated a better correlation with clinical features and was more valuable in NPR with leakage than non-weighted ISI, which previous studies conventionally used.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Aqueous microRNA profiling in age-related macular degeneration and polypoidal choroidal vasculopathy by next-generation sequencing.

    Choi, Yeong A / Jeong, Areum / Woo, Chang-Hoon / Cha, Soon Cheol / Park, Do Young / Sagong, Min

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 1274

    Abstract: Although many studies demonstrated the differences of clinical features, natural course, and response to treatment between typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV), differential microRNAs (miRNAs) ... ...

    Abstract Although many studies demonstrated the differences of clinical features, natural course, and response to treatment between typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV), differential microRNAs (miRNAs) expression in the aqueous humor (AH) between them has not been reported yet. We investigated the roles of miRNAs in the AH of patients with typical AMD and PCV using next-generation sequencing (NGS) and quantitative PCR (qPCR). Target genes and predicted pathways of miRNAs were investigated via pathway enrichment analysis using the Kyoto Encyclopedia of Genes and Genomes database. A total of 161 miRNAs from eyes with typical AMD and 185 miRNAs from eyes with PCV were differentially expressed. 33 miRNAs were commonly upregulated, and 77 miRNAs were commonly downregulated in both typical AMD and PCV groups. Among them, hsa-miR-140-5p, hsa-miR-374c-3p, and hsa-miR-200a-5p were differentially expressed and were predicted to regulate proteoglycans in cancer, p53 signaling pathway, Hippo signaling pathway, and adherens junction. The differential expression profiles and target gene regulation networks of AH miRNAs may contribute to the development of different pathological phenotypes in typical AMD and PCV. The results of this study provide novel insights into the pathogenesis, associated prognostic biomarkers, and therapeutic targets in AMD and PCV.
    MeSH term(s) Humans ; Choroid/pathology ; Polypoidal Choroidal Vasculopathy ; MicroRNAs ; Macular Degeneration/pathology ; High-Throughput Nucleotide Sequencing
    Chemical Substances MicroRNAs ; Mirn140 microRNA, human
    Language English
    Publishing date 2023-01-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-28385-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Clinical implications of choroidal vascular brightness using ultra-widefield indocyanine green angiography in polypoidal choroidal vasculopathy.

    Jeong, Areum / Yao, Xue / Lee, Kyungmin / Park, Sang Hyun / Sagong, Min

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 6400

    Abstract: Polypoidal choroidal vasculopathy (PCV) is characterized by choroidal vascular abnormalities including polypoidal lesion and branching vascular networks. Not only choroidal structural changes, but also choroidal hyperpermeability and congestion are also ... ...

    Abstract Polypoidal choroidal vasculopathy (PCV) is characterized by choroidal vascular abnormalities including polypoidal lesion and branching vascular networks. Not only choroidal structural changes, but also choroidal hyperpermeability and congestion are also thought to be involved in pathogenesis of PCV. We investigated choroidal vascular brightness intensity (CVB) using ultra-widefield indocyanine green angiography (UWF-ICGA) images and analyzed its association with clinical features in patients with PCV. In this study, 33 eyes with PCV and 27 eyes of age-matched controls were included. CVB was measured by extracting the enhanced pixels of choroidal vessels after the reference brightness across the images was adjusted to be uniform. Associations between choroidal vascular features and the clinical features of PCV were also determined. The mean CVB was higher in PCV than control eyes, regardless of the segmented region (all p < 0.001). CVB was also higher at the posterior pole than at the periphery, and the inferior quadrants were brighter than the superior quadrants in both the PCV and control group (all p < 0.05). In affected eyes, CVB was higher than in unaffected fellow eyes at the posterior pole, whereas there was no difference at the periphery. Posterior pole CVB correlated significantly with subfoveal choroidal thickness (r = 0.502, p = 0.005), polyp number (r = 0.366 p = 0.030), and the greatest linear dimension (r = 0.680, p = 0.040). Greatest linear dimension was positively correlated with CVB at posterior pole (p = 0.040), whereas SFCT or CVD in all regions didn't show the significant correlation. The UWF ICGA results showed an increase in CVB at the inferior quadrants and posterior pole, suggesting venous outflow congestion in PCV eyes. CVB might provide more substantial information on the phenotype than other choroidal vascular features.
    MeSH term(s) Humans ; Indocyanine Green ; Fluorescein Angiography ; Polypoidal Choroidal Vasculopathy ; Choroid/blood supply ; Tomography, Optical Coherence ; Polyps/diagnostic imaging ; Polyps/pathology ; Retrospective Studies ; Choroidal Neovascularization/diagnostic imaging ; Choroidal Neovascularization/pathology ; Coloring Agents/pharmacology
    Chemical Substances Indocyanine Green (IX6J1063HV) ; Coloring Agents
    Language English
    Publishing date 2023-04-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-31745-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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