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  1. Book ; Conference proceedings: Abstracts from the International Combined Meeting British Hip Society, Società Italiana dell'Anca

    Zagra, Luigi

    26-27 November 2015, Milan, Italy

    (Hip international ; volume 25, supplement 1 (November 2015))

    2015  

    Event/congress International Combined Meeting British Hip Society, Società Italiana dell'Anca (2015, Mailand)
    Author's details guest editors: Luigi Zagra, Fares Haddad
    Series title Hip international ; volume 25, supplement 1 (November 2015)
    Collection
    Language English
    Size S116 Seiten
    Publisher Wichtig
    Publishing place Milano, Italy
    Publishing country Italy
    Document type Book ; Conference proceedings
    HBZ-ID HT019335106
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3810 -25,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  2. Book ; Conference proceedings: Special issue on DDH from child to adult age

    Zagra, Luigi

    EHS meeting - 7th EFORT congress, Lisbon, June 5, 2005

    (Hip international : Suppl. ; 5)

    2007  

    Title variant DDH from child to adult age
    Institution European Hip Society
    European Federation of National Associations of Orthopaedics and Traumatology
    Author's details guest. ed.: Luigi Zagra
    Series title Hip international : Suppl. ; 5
    Hip international
    Hip international ; Suppl.
    Collection Hip international
    Hip international ; Suppl.
    Language English
    Size S141 S. : Ill., graph. Darst.
    Publisher Wichtig
    Publishing place Milano
    Publishing country Italy
    Document type Book ; Conference proceedings
    HBZ-ID HT016259571
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3810 -Suppl.5- not available for loan Zeitschriften-Lesesaal

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  3. Book ; Conference proceedings: Special issue on peri-prosthetic hip infections

    Romano, Carlo Luca / Zagra, Luigi

    an update ; conjoint meeting European Hip Society / European Bone and Joint Infection Society ; 12th EFORT congress, Copenhagen - June 3, 2011

    (Hip international : Suppl. ; 8)

    2012  

    Title variant Peri-prosthetic hip infections
    Institution European Federation of National Associations of Orthopaedics and Traumatology
    European Hip Society
    European Bone and Joint Infection Society
    Author's details guest ed. Luigi Zagra ; Carlo Luca Romanò
    Series title Hip international : Suppl. ; 8
    Hip international
    Hip international ; Suppl.
    Collection Hip international
    Hip international ; Suppl.
    Language English
    Size S90 S. : Ill., graph. Darst.
    Publisher Wichtig
    Publishing place Milano u.a.
    Publishing country Italy
    Document type Book ; Conference proceedings
    HBZ-ID HT017608516
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 3810 -Suppl.8- not available for loan Zeitschriften-Lesesaal

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  4. Article: Correction: D'Apolito, R.; Zagra, L. Uncemented Cups and Impaction Bone Grafting for Acetabular Bone Loss in Revision Hip Arthroplasty: A Review of Rationale, Indications, and Outcomes.

    D'Apolito, Rocco / Zagra, Luigi

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 16

    Abstract: The authors wish to make the following correction to this paper [ ... ]. ...

    Abstract The authors wish to make the following correction to this paper [...].
    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15165683
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Uncemented Cups and Impaction Bone Grafting for Acetabular Bone Loss in Revision Hip Arthroplasty: A Review of Rationale, Indications, and Outcomes.

    D'Apolito, Rocco / Zagra, Luigi

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 10

    Abstract: Total hip arthroplasty (THA) is increasingly performed in young patients and the number of revisions is estimated to rise over time. Acetabular osteolysis and bone loss are frequently encountered during revision and may be classified and treated in ... ...

    Abstract Total hip arthroplasty (THA) is increasingly performed in young patients and the number of revisions is estimated to rise over time. Acetabular osteolysis and bone loss are frequently encountered during revision and may be classified and treated in different ways. Impaction bone grafting (IBG) with morselized allograft offers a viable option. IBG was introduced over 40 years ago in combination with cemented cups, and is also used with uncemented cups. The impacted bone chips act as a void filler to restore bone stock; once incorporated they are substituted by host bone. Surgery entails assessment of the defect, acetabular preparation, preparation of the morselized graft, impaction of the graft, and cup implantation. Satisfactory medium- and long-term results have now been reported in most studies. With the advent of high-porosity cups, indications have been extended, enhancing the potential of IBG, in which primary stability of the cup to the host bone is essential for a successful procedure. Synthetic bone substitutes have also been used in combination with allogenic grafts and may extend the original technique for which long-term studies are warranted.
    Language English
    Publishing date 2022-05-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15103728
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Advances in hip arthroplasty surgery: what is justified?

    Zagra, Luigi

    EFORT open reviews

    2017  Volume 2, Issue 5, Page(s) 171–178

    Abstract: Total hip arthroplasty (THA) surgery has shown dramatic changes in terms of increased number of procedures and of technical development in recent years. It has been described as "the operation of the ... ...

    Abstract Total hip arthroplasty (THA) surgery has shown dramatic changes in terms of increased number of procedures and of technical development in recent years. It has been described as "the operation of the 20
    Language English
    Publishing date 2017-05-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2844421-8
    ISSN 2058-5241 ; 2058-5241 ; 2396-7544
    ISSN (online) 2058-5241
    ISSN 2058-5241 ; 2396-7544
    DOI 10.1302/2058-5241.2.170008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: CORR Insights(®): Do the Reasons for Ceramic-on-ceramic Revisions Differ From Other Bearings in Total Hip Arthroplasty?

    Zagra, Luigi

    Clinical orthopaedics and related research

    2016  Volume 474, Issue 10, Page(s) 2200–2201

    MeSH term(s) Arthroplasty, Replacement, Hip ; Ceramics ; Hip Prosthesis ; Prosthesis Design ; Prosthesis Failure
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
    DOI 10.1007/s11999-016-4971-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.188: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Best practice in digital orthopaedics.

    Halm-Pozniak, Agnieszka / Lohmann, Christoph H / Zagra, Luigi / Braun, Benedikt / Gordon, Max / Grimm, Bernd

    EFORT open reviews

    2023  Volume 8, Issue 5, Page(s) 283–290

    Abstract: Digitization in orthopaedics and traumatology is an enormously fast-evolving field with numerous players and stakeholders. It will be of utmost importance that the different groups of technologists, users, patients, and actors in the healthcare systems ... ...

    Abstract Digitization in orthopaedics and traumatology is an enormously fast-evolving field with numerous players and stakeholders. It will be of utmost importance that the different groups of technologists, users, patients, and actors in the healthcare systems learn to communicate in a language with a common basis. Understanding the requirements of technologies, the potentials of digital application, their interplay, and the combined aim to improve health of patients, would lead to an extraordinary chance to improve health care. Patients' expectations and surgeons' capacities to use digital technologies must be transparent and accepted by both sides. The management of big data needs tremendous care as well as concepts for the ethics in handling data and technologies have to be established while also considering the impact of withholding or delaying benefits thereof. This review focuses on the available technologies such as Apps, wearables, robotics, artificial intelligence, virtual and augmented reality, smart implants, and telemedicine. It will be necessary to closely follow the future developments and carefully pay attention to ethical aspects and transparency.
    Language English
    Publishing date 2023-05-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2844421-8
    ISSN 2058-5241 ; 2058-5241 ; 2396-7544
    ISSN (online) 2058-5241
    ISSN 2058-5241 ; 2396-7544
    DOI 10.1530/EOR-23-0081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Inflammatory Treatment Used to Mimic Osteoarthritis and Patients' Synovial Fluid Have Divergent Molecular Impact on Chondrocytes In Vitro.

    Ragni, Enrico / De Luca, Paola / Valli, Federico / Zagra, Luigi / de Girolamo, Laura

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: Osteoarthritis (OA) is a chronic disease characterized by joint tissue disruption and inflammation with a paucity of therapeutic options. Chondrocyte in vitro models are commonly used as the first step in evaluating new approaches and rely on the ... ...

    Abstract Osteoarthritis (OA) is a chronic disease characterized by joint tissue disruption and inflammation with a paucity of therapeutic options. Chondrocyte in vitro models are commonly used as the first step in evaluating new approaches and rely on the stimulation of an OA-like phenotype with inflammation often the method of choice. Inflammatory priming is frequently based on cytokines used at concentrations very far from the reality in the patients' synovial fluid (SF). The aim of this work was to compare the transcriptional response of chondrocytes to different inflammatory conditions: the high levels of IL1β that are used for standardized inflammation protocols, OA-SF, IL1β, IL6 and IFNγ at SF-like concentrations both individually and simultaneously to mimic a simplified "in vitro" SF. Both high IL1β and OA-SF strongly influenced chondrocytes, while SF-like concentrations of cytokines gave weak (IL1β alone or in combination) or no (IL6 and IFNγ alone) outcomes. Chondrocytes under the two most powerful polarizing conditions had a clearly distinct fingerprint, with only a shared albeit molecularly divergent effect on ECM stability, with IL1β mainly acting on ECM degrading enzymes and OA-SF accounting for a higher turnover in favor of fibrous collagens. Moreover, OA-SF did not induce the inflammatory response observed with IL1β. In conclusion, although partially similar in the endpoint phenotype, this work intends to encourage reflection on the robustness of inflammation-based in vitro OA models for molecular studies on chondrocytes.
    MeSH term(s) Humans ; Synovial Fluid ; Chondrocytes ; Interleukin-6/genetics ; Osteoarthritis/drug therapy ; Cytokines/therapeutic use ; Inflammation
    Chemical Substances Interleukin-6 ; Cytokines
    Language English
    Publishing date 2023-01-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Do prior intra-articular injections impact on the risk of periprosthetic joint infection in patients undergoing total hip arthroplasty? A meta-analysis of the current evidences with a focus on the timing of injection before surgery.

    Saracco, Michela / Ciriello, Vincenzo / D'Angelo, Fabio / Zagra, Luigi / Solarino, Giuseppe / Logroscino, Giandomenico

    EFORT open reviews

    2023  Volume 8, Issue 6, Page(s) 459–467

    Abstract: Purpose: Intra-articular injection is a well-established and increasingly used treatment for the patient with mild-to-moderate hip osteoarthritis. The objectives of this literature review and meta-analysis are to evaluate the effect of prior intra- ... ...

    Abstract Purpose: Intra-articular injection is a well-established and increasingly used treatment for the patient with mild-to-moderate hip osteoarthritis. The objectives of this literature review and meta-analysis are to evaluate the effect of prior intra-articular injections on the risk of periprosthetic joint infection (PJI) in patients undergoing total hip arthroplasty (THA) and to try to identify which is the minimum waiting time between hip injection and replacement in order to reduce the risk of infection.
    Methods: The database of PubMed, Embase, Google Scholar and Cochrane Library was systematically and independently searched, according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. To assess the potential risk of bias and the applicability of the evidence found in the primary studies to the review, the Newcastle-Ottawa scale (NOS) was used. The statistical analysis was performed by using the software 'R' version 4.2.2.
    Results: The pooling of data revealed an increased risk of PJI in the injection group that was statistically significative (P = 0.0427). In the attempt to identify a 'safe time interval' between the injection and the elective surgery, we conducted a further subgroup analysis: in the subgroup 0-3 months, we noted an increased risk of PJI after injection.
    Conclusions: Intra-articular injection is a procedure that may increase the risk of developing periprosthetic infection. This risk is higher if the injection is performed less than 3 months before hip replacement.
    Language English
    Publishing date 2023-06-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2844421-8
    ISSN 2058-5241 ; 2058-5241 ; 2396-7544
    ISSN (online) 2058-5241
    ISSN 2058-5241 ; 2396-7544
    DOI 10.1530/EOR-23-0028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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