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  1. Article: Penetrující poranění srdce a velkých cév – patnáctiletá zkušenost kardiochirurgického servisu v rámci primárního traumacentra.

    Šimek, M / Konečný, J / Hájek, R / Čižmář, I / Kutěj, V / Lonský, V

    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca

    2018  Volume 85, Issue 2, Page(s) 144–148

    Abstract: PURPOSE OF THE STUDY Outcome analysis of penetrating cardiac and great vessels injury within the 15-year existence of the cardiac surgery service as a part of the major trauma centre of the University Hospital Olomouc MATERIAL AND METHODS Retrospective ... ...

    Title translation Penetrating Injuries of the Heart and Great Vessels - Fifteen Years of Experience of the Cardiac Surgery Service as a Part of the Major Trauma Centre.
    Abstract PURPOSE OF THE STUDY Outcome analysis of penetrating cardiac and great vessels injury within the 15-year existence of the cardiac surgery service as a part of the major trauma centre of the University Hospital Olomouc MATERIAL AND METHODS Retrospective analysis of a group of a total of 16 patients who underwent a surgery for penetrating cardiac and great vessels injury since II/2002 to XI/2016. The dominant causes of penetrating trauma were stab injuries (15 patients, 94%), in one patient only (6%) it was a gunshot injury. The mean age of the patients included in the group was 42.9 ± 16.1 years, with men significantly prevailing (13 patients, 81%). A total of 7 injured persons (44%) were haemodynamically stable when admitted, 9 injured persons (56%) were unstable or in critical condition. The average transfer distance was 48.8 ± 34.5 km; the injured were admitted on average 115.9 ± 154.8 minutes after being injured. Preoperatively, all the injured suffered from pericardial effusion (>5 mm) confirmed by TTE (81%) or CTA (19%). In 4 patients (25%) pericardial drainage for cardiac tamponade was performed before surgery. RESULTS All the penetrating cardiac and great vessels injuries were repaired by cardiac surgeon, in one case only (6%) the extracorporeal circulation support was used. The injury of coronary arteries was in one case managed by CABG and in the other case by ligation of the peripheral part of the coronary artery. In 4 patients (25%) also a penetrating injury of other organs was simultaneously managed. The mean ICU stay reached 85.8 ± 91.9 hours, on average 5.6 ± 9.3 units of red blood cells were administered during the in-hospital stay which lasted on average 7.1 ± 2.4 days. In the group a nonsignificant increase of left ventricular ejection fraction (44.1 ± 4.7 vs. 49.3 ± 3.2, p = 0.882) was reported at discharge of the injured patients. One patient died on the 78 th day of hypoxic brain damage (6% three-month mortality). The long-term survival analysis showed 94% one-year and 88% five-year cumulative survival in the group. DISCUSSION The incidence of the penetrating cardiac and great vessels injury is directly dependent on the crime level in the respective countries and regions. A cardiac arrest, severe hemodynamic instability, unconsciousness, serious concomitant injury, gunshot injury, multiple or atrial injury represent independent predictors of death in these injuries. The total three-month mortality in penetrating cardiac and great vessels injury ranges from 18 to 42%, the presence of vital signs at the time of hospital admission is associated with 78-92% probability of survival. The surviving patients show excellent long-term results with the exception of those who suffered a severe damage to valve apparatus or with significantly depressed left ventricular function. CONCLUSIONS Our experience proves a high survival rate of patients with penetrating cardiac and great vessels injury. The centralisation of the care into the major trauma centre with a cardiac surgery background, a unified treatment algorithm, and a vital interdisciplinary cooperation are the key goal of successful management of these injuries. Key words:penetrating injury, cardiac injury, great vessel injury, outcome. Práce byla podpořena programem institucionální podpor.
    MeSH term(s) Adult ; Coronary Vessels/injuries ; Coronary Vessels/surgery ; Crime ; Critical Care ; Czech Republic/epidemiology ; Female ; Heart Injuries/mortality ; Heart Injuries/surgery ; Humans ; Length of Stay ; Male ; Middle Aged ; Retrospective Studies ; Survival Rate ; Trauma Centers ; Wounds, Gunshot/mortality ; Wounds, Gunshot/surgery ; Wounds, Stab/mortality ; Wounds, Stab/surgery
    Language Czech
    Publishing date 2018-11-19
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 418889-5
    ISSN 0001-5415
    ISSN 0001-5415
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pectoral muscle flap with V-Y skin paddle for covering sternal defects.

    Molitor, Martin / Simek, Martin / Lonský, Vladimír / Kaláb, Martin / Veselý, Jiří / Zálešák, Bohumil

    The Annals of thoracic surgery

    2012  Volume 94, Issue 5, Page(s) e131–3

    Abstract: ... flap with a V-Y skin paddle. ...

    Abstract Deep sternal wound infection (DSWI) after a cardiac operation is a rare but serious complication associated with significant morbidity and mortality. It can lead to wound dehiscence with sternal osteomyelitis and both bony and soft tissue residual defects. When the infection is eradicated, reconstruction of the thoracic wall remains the main challenge. Tissue used for covering the defect must be well nourished and sutures must be tension free. We present our unique modification of the method using the pectoral muscle axial flap with a V-Y skin paddle.
    MeSH term(s) Aged ; Female ; Humans ; Male ; Middle Aged ; Pectoralis Muscles/transplantation ; Reconstructive Surgical Procedures/methods ; Retrospective Studies ; Sternum/surgery ; Surgical Flaps ; Surgical Wound Infection/surgery
    Language English
    Publishing date 2012-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2012.08.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Article ; Online: Gulags, crime, and elite violence

    Lonsky, Jakub

    Origins and consequences of the Russian mafia

    2020  

    Abstract: This paper studies the origins and consequences of the Russian mafia (vory-v-zakone). I web scraped ...

    Abstract This paper studies the origins and consequences of the Russian mafia (vory-v-zakone). I web scraped a unique dataset that contains detailed biographies of more than 5,000 mafia leaders operating in 15 countries of the (former) Soviet Union at some point between 1916 and 2017. Using this data, I first show that the Russian mafia originated in the Gulag - the Soviet system of forced labor camps which housed around 18 million prisoners in the 1920s1950s period. Second, I document that the distance to the nearest camp is a strong negative predictor of mafia presence in Russia's communities in the early post-Soviet period. Finally, using an instrumental variable approach which exploits the spatial distribution of the gulags, I examine the effects of mafia presence on local crime and elite violence in mid-1990s Russia. In particular, I show that the communities with mafia presence experienced a dramatic rise in crime driven by turf wars which erupted among rival clans around 1993 and persisted for much of the 1990s. Further heterogeneity analysis reveals that mafia presence led to a spike in attacks against businessmen, fellow criminals, as well as law enforcement officers and judges, while politically-motivated violence remained unaffected.
    Keywords ddc:330 ; K42 ; N40 ; P16 ; P37 ; Russian mafia ; Gulag ; Post-socialist transition ; Crime ; Elite violence
    Subject code 940
    Language English
    Publisher Helsinki: Bank of Finland, Institute for Economies in Transition (BOFIT)
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Article ; Online: Gulags, Crime, and Elite Violence

    Lonsky, Jakub

    Origins and Consequences of the Russian Mafia

    2020  

    Abstract: This paper studies the origins and consequences of the Russian mafia (vory-v-zakone). Using ...

    Abstract This paper studies the origins and consequences of the Russian mafia (vory-v-zakone). Using a unique web scraped dataset containing detailed biographies of more than 5,000 mafia leaders, I first show that the Russian mafia originated in the Soviet Gulag archipelago, and could be found near the gulags' initial locations in mid-1990s Russia, some three decades after the camps were officially closed down. Then, using an instrumental variable approach that exploits the proximity of the Russian mafia to the gulags, I show that Russian communities with mafia presence in the mid-1990s experienced a dramatic rise in crime driven by elite violence which erupted shortly after the collapse of the Soviet Union in 1991. The violence – initially confined to the criminal underworld – eventually spilled over, leading to indiscriminate attacks against local businessmen, managers of state-owned enterprises, judges, and members of the state security apparatus. However, there was no increase in politically-motivated violence, suggesting a widespread collusion between the mafia and local politicians in the early post-Soviet Russia.
    Keywords ddc:330 ; K42 ; N40 ; P16 ; P37 ; Russian mafia ; Gulag ; Post-socialist transition ; Crime ; Elite violence
    Subject code 940
    Language English
    Publisher Essen: Global Labor Organization (GLO)
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book: Mimotělní oběh v klinické praxi

    Lonský, Vladimír

    (Avicenum)

    2004  

    Author's details Vladimír Lonský
    Series title Avicenum
    MeSH term(s) Extracorporeal Circulation
    Language Czech
    Size 215 p. :, ill.
    Publisher Grada
    Publishing place Praha
    Document type Book
    ISBN 9788024706535 ; 8024706539
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article: Postperfuzní syndrom po operaci v mimotĕlním obĕhu.

    Brtko, M / Lonský, V / Kunes, P / Dominik, J / Kubícek, J

    Acta medica (Hradec Kralove). Supplementum

    1999  Volume 42, Issue 1, Page(s) 13–16

    Abstract: Postperfusion syndrome (PPS) is a dreaded complication of cardiac surgery operation in extracorporeal circulation (ECC). Four factors play a key role in its pathophysiology: 1. contact of blood with the material of ECC, 2. release of activated leucocytes ...

    Title translation The post-perfusion syndrome after operations performed with extracorporeal circulation.
    Abstract Postperfusion syndrome (PPS) is a dreaded complication of cardiac surgery operation in extracorporeal circulation (ECC). Four factors play a key role in its pathophysiology: 1. contact of blood with the material of ECC, 2. release of activated leucocytes from pulmonary bed after the release of aortic cross-clamp, 3. translocation of endotoxin due to gut ischemia and its consequent reperfusion, 4. activation of coagulation, fibrinolytic, kallikrein-kinin and complement systems. The occurrence of PPS can be limited by reducing the ECC time and/or cross-clamp time, by using membrane oxygenator in the system of ECC, by using polyester or polypropylene in the set of ECC, by using heparin-coated set or leucocyte filter in the system of ECC, by application of pharmacological dosis of corticosteroids prior to the ECC, by early enteral nutrition. In eligible patients it is possible to eliminate the risk of PPS completely by using the operation without ECC. The experience of the authors with above mentioned problems is given and confronted with literature.
    MeSH term(s) Cardiac Surgical Procedures/adverse effects ; Cardiopulmonary Bypass/adverse effects ; Humans ; Reperfusion Injury/etiology ; Reperfusion Injury/physiopathology ; Reperfusion Injury/prevention & control ; Systemic Inflammatory Response Syndrome/etiology ; Systemic Inflammatory Response Syndrome/physiopathology ; Systemic Inflammatory Response Syndrome/prevention & control
    Language Czech
    Publishing date 1999
    Publishing country Czech Republic
    Document type English Abstract ; Journal Article
    ISSN 1211-247X
    ISSN 1211-247X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Sledování zmĕn metabolismu a krevního průtoku v kosterním svalu bĕhem srdecní operace v mimotĕlním obĕhu v normotermii a hypotermii pomocí intersticiální mikrodialýzy.

    Mand'ák, J / Zivný, P / Lonský, V / Palicka, V / Kakrdová, D / Marsíková, M / Kunes, P / Kubícek, J

    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti

    2003  Volume 82, Issue 9, Page(s) 460–468

    Abstract: Aim: Hypoperfusion of peripheral tissues and splanchnic organs during cardiac surgery in extracorporeal circulation may lead to the origin of serious complications. The aim of the study was to monitor metabolism and blood pressure in interstital ... ...

    Title translation Interstitial microdialysis study of changes in metabolism and blood flow in skeletal muscles during cardiac surgery with normothermic and hypothermic extracorporeal circulation.
    Abstract Aim: Hypoperfusion of peripheral tissues and splanchnic organs during cardiac surgery in extracorporeal circulation may lead to the origin of serious complications. The aim of the study was to monitor metabolism and blood pressure in interstital peripheral tissue, skeletal muscle, during the operation on the patient with extracorporeal circulation (ECC) in an early post-operation period by means of microdialysis.
    Methods: The interstitial microdialysis is a minimally invasive method for the biochemical monitoring of metabolic changes and blood pressure in extracellular space of tissue. The substances in interstitium pass across a semipermeable membrane of the inserted microdialysis probe and may be analyzed. Microdialysis in this study was performed by means of two microdialysis probes CMA (CMA Microdialysis AB, Sweden) inserted into the deltoid muscle of the surgically treated patient. The probes were perfused by the Ringer solution at the rate of 0.3 ml/hour. The dialysates were sampled in the following intervals: beginning of the operation, beginning of ECC, end of ECC, end of the operation, two hours during the post-operation period. Standard biochemical methods were to evaluate, in the dialysates, glucose, urea, glycerol and lactate. The blood flow in the interstitium was monitored by means of dynamic microdialysis of gentamycine as a marker. Microdialysis was performed in 40 patients with ischemic heart disease, operated on in the extracorporeal circulation. In 20 patients the ECC was performed in normothermia (NT), while in the other 20 patients it was made in hypothermia (HT).
    Results: In both groups, NT versus HT, a similar dynamism of interstitial concentration of the observed substances in relation to the operation phase and in early post-operation period. Low initial concentrations were gradually increasing during the extracorporeal circulation and increased further after the end of extracorporeal circulation and also in the subsequent phase of the operation. The concentration values of the analytes under observation were higher in the groups operated on under normothermia, apparently due to normal cellular activity during normothermia (versus values in hypothermia). Immediately after the operation the observed values decreased in the both groups and subsequently gradually increased in the post-operation period in the both groups. The trend of dynamic changes of the observed analytes, selected as compounds indicating metabolic activity of skeletal muscles during hypothermia documents a lower metabolic activity of the cells during hypothermia and its marked increase (against NT) in the phase of subsequent normalization of the tissue temperature. Analysis of the concentrations of lactate, as a compounds mapping anaerobic metabolism of skeletal muscle, revealed similar dynamic changes in the both groups (NT vs. HT). There were no significant differences, related to the phase of the operation or the phase of immediate post-operation course when the both groups were compared. The analysis of gentamycine concentrations as a flow marker revealed lower gentamycine concentrations in dialysate during the operation, ECC and the early post-operation course in the group operated on in normotheramia (vs. HT), indicating a higher tissue flow in skeletal muscle against the group of patients operated on under hypothermia.
    Conclusion: The results of the microdialysis study demonstrated dynamic changes in interstitial concentrations of the observed compounds (glucose, urea, glycerol and lactate) related to the phase of operation on the heart in extracorporeal circulation and in early post-operation period. A higher perfusion of skeletal muscle was documented in patients operated on under normothermia. It became obvious that the dynamism in the changes of the compounds observed in the interstitium of skeletal muscle was determined by metabolic activity of the tissue as well as by blood flow in the muscle interstitium.
    MeSH term(s) Aged ; Coronary Artery Bypass ; Extracellular Space/chemistry ; Extracorporeal Circulation/methods ; Female ; Humans ; Male ; Microdialysis ; Middle Aged ; Muscle, Skeletal/blood supply ; Muscle, Skeletal/metabolism ; Regional Blood Flow ; Temperature
    Language Czech
    Publishing date 2003-09
    Publishing country Czech Republic
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 414059-x
    ISSN 1805-4579 ; 0035-9351
    ISSN (online) 1805-4579
    ISSN 0035-9351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Perforace zaludku jako casná komplikace chirurgické revaskularizace myokardu v mimotĕlním obĕhu.

    Mand'ák, J / Lonský, V / Hajzman, Z

    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti

    2001  Volume 80, Issue 8, Page(s) 424–427

    Abstract: The authors describe the case of a man with ischaemic heart disease after revascularization of the myocardium by an aortocoronary bypass using extracorporeal circulation. The early postoperative course was complicated by perforation of a gastric ulcer. ... ...

    Title translation Gastric perforation as an early complication of surgical myocardial revascularization using extracorporeal circulation.
    Abstract The authors describe the case of a man with ischaemic heart disease after revascularization of the myocardium by an aortocoronary bypass using extracorporeal circulation. The early postoperative course was complicated by perforation of a gastric ulcer. The condition was successfully resolved by an urgent operation, suture of the perforated stomach with toilet of the abdominal cavity. In the discussion the authors analyze the causes of the possible development of gastrointestinal complications after cardiac surgery, in particular the influence of extracorporeal circulation and other specific effects during cardiac surgery and during the immediate postoperative period.
    MeSH term(s) Cardiopulmonary Bypass/adverse effects ; Coronary Artery Bypass/adverse effects ; Humans ; Male ; Middle Aged ; Peptic Ulcer Perforation/etiology ; Recurrence
    Language Czech
    Publishing date 2001-08
    Publishing country Czech Republic
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 414059-x
    ISSN 1805-4579 ; 0035-9351
    ISSN (online) 1805-4579
    ISSN 0035-9351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Conference proceedings: Platelet function during platelet-rich plasma squestration in complex cardiac surgery

    Hajek, R. / Fluger, I. / Lonsky, V. / Santavy, P. / Zuscich, O. / Caletka, P. / Slavík, L. / Úlehlová, J.

    Hämostaseologie

    2024  Volume 44, Issue S 01

    Event/congress GTH Congress 2024 - 68th Annual Meeting of the Society of Thrombosis and Haemostasis Research - Building Bridges in Coagulation, Vienna, Austria, 2024-03-27
    Language English
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 801512-0
    ISSN 2567-5761 ; 0720-9355
    ISSN (online) 2567-5761
    ISSN 0720-9355
    DOI 10.1055/s-0044-1779091
    Database Thieme publisher's database

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  10. Article: Bakteriologické nálezy v bronchiálním sekretu dolních dýchacích cest resekovaných plic.

    Lonský, V / Mand'ák, J / Simek, J / Lonská, V

    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti

    1990  Volume 69, Issue 6, Page(s) 385–390

    Abstract: The authors investigated during operation the bacteriological findings in the bronchial secretion of the respiratory pathways of resected lungs. Of 100 patients whom they included in the group they detected a positive finding in 42. Wound in 27 patients. ...

    Title translation Bacteriological findings in bronchial secretions of the lower respiratory tract in resected lungs.
    Abstract The authors investigated during operation the bacteriological findings in the bronchial secretion of the respiratory pathways of resected lungs. Of 100 patients whom they included in the group they detected a positive finding in 42. Wound in 27 patients. Twenty of them had a positive bacteriological finding in the lower respiratory pathways. The authors discuss the problem of prophylactic use of antibiotics in pulmonary surgery. Based on data in the literature and their own observations, the authors recommend preventive administration of antibiotics in pulmonary surgery.
    MeSH term(s) Adolescent ; Adult ; Aged ; Bacteria/isolation & purification ; Bronchi/microbiology ; Child ; Female ; Humans ; Male ; Middle Aged ; Pneumonectomy ; Surgical Wound Infection/microbiology
    Language Czech
    Publishing date 1990-06
    Publishing country Czech Republic
    Document type English Abstract ; Journal Article
    ZDB-ID 414059-x
    ISSN 1805-4579 ; 0035-9351
    ISSN (online) 1805-4579
    ISSN 0035-9351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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