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  1. Article ; Online: Effectiveness of Mask Wearing to Control Community Spread of SARS-CoV-2.

    Brooks, John T / Butler, Jay C

    JAMA

    2021  Volume 325, Issue 10, Page(s) 998–999

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/transmission ; Disease Transmission, Infectious/prevention & control ; Disease Transmission, Infectious/statistics & numerical data ; Humans ; Masks
    Language English
    Publishing date 2021-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2021.1505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The significance of heterotopic ossification following total ankle arthroplasty: a systematic review and meta-analysis.

    Butler, James J / Healy, Hazel / Anil, Utkarsh / Habibi, Akram / Azam, Mohammad T / Walls, Raymond J / Kennedy, John G

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

    2024  

    Language English
    Publishing date 2024-03-12
    Publishing country France
    Document type Journal Article
    ZDB-ID 1231084-0
    ISSN 1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
    ISSN (online) 1432-1068
    ISSN 1633-8065 ; 0948-4817 ; 0940-3264
    DOI 10.1007/s00590-024-03866-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Safe Sex After Total Hip Arthroplasty: Using Computed Tomography-Based Robotics to Evaluate "At-Risk" Sexual Positions.

    Stegelmann, Samuel D / Butler, Justin T / Hiatt, John L / Bullock, Matthew W

    The Journal of arthroplasty

    2023  Volume 39, Issue 2, Page(s) 433–440.e4

    Abstract: Background: Total hip arthroplasty (THA) can improve sexual satisfaction, but fear of dislocation can lead to sexual difficulties following this procedure. Previous kinematic research identified 4 sexual positions in women and 2 in men that were ... ...

    Abstract Background: Total hip arthroplasty (THA) can improve sexual satisfaction, but fear of dislocation can lead to sexual difficulties following this procedure. Previous kinematic research identified 4 sexual positions in women and 2 in men that were considered at risk for impingement. This study aimed to validate these findings using current robotic THA simulations.
    Methods: The 3-dimensional renderings from 12 patients who received computed tomography (CT)-based robotic THA were used to assess for prosthetic and/or bony impingement among 12 popular sexual positions. There were 9 cup orientations tested for each position (a combination of anteversion [0 °, 15 °, and 30 °] and inclination [40 °, 45 °, and 60 °]). The at-risk positions were tested again using the unique hip positions and cup orientations where previous geometric modeling data found impingement to occur.
    Results: Using mean hip positions, impingement occurred in at least 1 patient in 1 of the 12 positions for women (position 5) and 5 of the 12 positions for men (positions 1, 5, 8, 10, and 11). Among the at-risk positions, impingement occurred in none of the 2 at-risk women positions (0 of 17 cup orientations) and in both at-risk men positions (9 of 9 cup orientations for position 8 and 1 of 1 for position 11).
    Conclusion: Recreating popular and at-risk sexual positions following THA with a CT-based robotics system yielded results that were inconsistent with previous geometric modeling data. Resolving these discrepancies is crucial for surgeons to provide accurate postoperative patient education. The CT-based robotic systems may provide necessary input to feasibly individualize such recommendations, but current limitations in CT-based robotics require continued attention and innovation.
    MeSH term(s) Male ; Humans ; Female ; Arthroplasty, Replacement, Hip/methods ; Hip Joint/diagnostic imaging ; Hip Joint/surgery ; Hip Prosthesis ; Safe Sex ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2023.08.022
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  4. Article ; Online: Transmissible ER stress shapes the leukemic microenvironment.

    Butler, John T / Kurre, Peter

    Oncotarget

    2019  Volume 10, Issue 41, Page(s) 4080–4082

    Language English
    Publishing date 2019-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2560162-3
    ISSN 1949-2553 ; 1949-2553
    ISSN (online) 1949-2553
    ISSN 1949-2553
    DOI 10.18632/oncotarget.27012
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  5. Article ; Online: Polyvinyl alcohol hydrogel implant for the treatment of hallux rigidus is associated with a high complication rate and moderate failure rate at short-term follow-up: a systematic review.

    Butler, James J / Dhillon, Ravneet / Wingo, Taylor / Lin, Charles C / Samsonov, Alan P / Azam, Mohammad T / Kennedy, John G

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

    2024  

    Abstract: Purpose: Moderate-to-severe hallux rigidus is a debilitating pathology that is optimally treated with surgical intervention. Arthrodesis produces reliable clinical outcomes but is limited by restriction in 1st metatarsophalangeal joint range of motion. ... ...

    Abstract Purpose: Moderate-to-severe hallux rigidus is a debilitating pathology that is optimally treated with surgical intervention. Arthrodesis produces reliable clinical outcomes but is limited by restriction in 1st metatarsophalangeal joint range of motion. The advent of polyvinyl alcohol hydrogel (PVA) implants have produced early promise based on initial trials, but more recent studies have called into question the efficacy of this procedure. The purpose of this systematic review was to evaluate the clinical and radiological outcomes following the use of PVA for hallux rigidus.
    Methods: The MEDLINE, EMBASE and Cochrane library databases were systematically reviewed using the preferred reporting items for systematic reviews and meta-analyses guidelines. 18 studies were included.
    Results: In total, 1349 patients (1367 feet) underwent PVA at a weighted mean follow-up of 24.1 ± 11.1 months. There were 168 patients (169 feet) included in the cheilectomy cohort and 322 patients (322 feet) included in the arthrodesis cohort. All 3 cohorts produced comparable improvements in subjective clinical outcomes. Postoperative imaging findings in the PVA cohort included joint space narrowing, peri-implant fluid, peri-implant edema and erosion of the proximal phalanx. The complication rate in the PVA cohort, cheilectomy cohort and arthrodesis cohort was 27.9%, 11.8% and 24.1%, respectively. The failure rates in the PVA cohort, cheilectomy cohort and arthrodesis cohort was 14.8%, 0.3% and 9.0%, respectively.
    Conclusion: This systematic review demonstrated that PVA produced a high complication rate (27.9%) together with concerning postoperative imaging findings at short-term follow-up. In addition, a moderate failure rate (14.8%) and secondary surgical procedure rate (9.5%) was noted for the PVA cohort. The findings of this review calls into question the efficacy and safety of PVA for the treatment of hallux rigidus.
    Level of evidence: IV.
    Language English
    Publishing date 2024-03-30
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 1231084-0
    ISSN 1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
    ISSN (online) 1432-1068
    ISSN 1633-8065 ; 0948-4817 ; 0940-3264
    DOI 10.1007/s00590-024-03895-w
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  6. Article ; Online: The Role of Needle Arthroscopy in the Assessment and Treatment of Ankle Sprains.

    Butler, James J / Brash, Andrew I / Azam, Mohammad T / DeClouette, Brittany / Kennedy, John G

    Foot and ankle clinics

    2023  Volume 28, Issue 2, Page(s) 345–354

    Abstract: Lateral ankle ligament complex injuries are most commonly managed nonoperatively. If no improvements have been made following conservative management, surgical intervention is warranted. Concerns have been raised regarding complication rates following ... ...

    Abstract Lateral ankle ligament complex injuries are most commonly managed nonoperatively. If no improvements have been made following conservative management, surgical intervention is warranted. Concerns have been raised regarding complication rates following open and traditional arthroscopic anatomical repair. In-office needle arthroscopic anterior talo-fibular ligament repair provides a minimally invasive arthroscopic approach to the diagnosis and treatment of chronic lateral ankle instability. The limited soft tissue trauma facilitates rapid return to daily and sporting activities making this an attractive alternative approach to lateral ankle ligament complex injuries.
    MeSH term(s) Humans ; Ankle Joint/surgery ; Arthroscopy ; Lateral Ligament, Ankle/surgery ; Ankle Injuries/diagnosis ; Ankle Injuries/surgery ; Sprains and Strains/diagnosis ; Sprains and Strains/surgery ; Joint Instability/diagnosis ; Joint Instability/etiology ; Joint Instability/surgery
    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2051688-5
    ISSN 1558-1934 ; 1083-7515
    ISSN (online) 1558-1934
    ISSN 1083-7515
    DOI 10.1016/j.fcl.2023.01.005
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  7. Article ; Online: Tranexamic acid reduces perioperative blood loss and postoperative hemoglobin loss during total ankle arthroplasty: A systematic review and meta-analysis of clinical comparative studies.

    Butler, James J / Rajivan, Ragul / Konar, Kishore / Anil, Utkarsh / Azam, Mohammad T / Walls, Raymond / Kennedy, John G

    Journal of ISAKOS : joint disorders & orthopaedic sports medicine

    2024  

    Abstract: Importance: Peri-operative blood loss during joint replacement procedures is a modifiable risk factor that impacts wound complications, hospital stay and total costs. Tranexamic acid (TXA) is an anti-fibrinolytic that has been widely used in orthopedic ... ...

    Abstract Importance: Peri-operative blood loss during joint replacement procedures is a modifiable risk factor that impacts wound complications, hospital stay and total costs. Tranexamic acid (TXA) is an anti-fibrinolytic that has been widely used in orthopedic surgery, but its efficacy in the setting of total ankle arthroplasty (TAA) has not been quantified to date.
    Aim: The purpose of this systematic review and meta-analysis was to evaluate the efficacy and safety of administering TXA in patients undergoing TAA.
    Evidence review: The Medline, Embase and Cochrane library databases were systematically reviewed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Five comparative studies examining blood loss following administration of TXA for patients undergoing TAA were included. The outcome measures of interest were blood loss, reduction in hemoglobin concentration, transfusion requirements, total complications and wound complications.
    Findings: In total, 194 patients received TXA and 187 patients did not receive TXA while undergoing TAA. Based on the common-effects model for total blood loss for the TXA group versus control, the standardized mean difference (SMD) was -0.7832 (95% CI, -1.1544, -0.4120; P ​< ​0.0001), in favor of lower total blood loss for TXA. Based on the random-effects model for reduction in hemoglobin for the TXA group versus control, the SMD was -0.9548 (95% CI, -1.7850, -0.1246; P ​= ​0.0242) in favor of lower hemoglobin loss for TXA. Based on the random-effects model for total complications for the TXA group versus control, the risk ratio was 0.512 (95% CI, 0.1588, 1.6512; P ​= ​0.1876), in favor of lower total complications for TXA but this was not statistically significant.
    Conclusions: This current review demonstrated that administration of TXA led to a reduction in blood loss and hemoglobin loss without an increased risk of the development of venous thromboembolism in patients undergoing TAA. No difference was observed with respect to total complication rates between the TXA cohort and the control group. TXA appears to be an effective hemostatic agent in the setting of TAA, but further studies are necessary to identify the optimal timing, dosage and route of TXA during TAA.
    Level of evidence: III.
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2059-7762
    ISSN (online) 2059-7762
    DOI 10.1016/j.jisako.2024.03.009
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  8. Article ; Online: In-Office Needle Arthroscopy for the Foot and Ankle.

    Duenes, Matthew L / Azam, Mohammad T / Butler, James J / Weiss, Matthew B / Kennedy, John G

    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

    2023  Volume 39, Issue 5, Page(s) 1129–1130

    Abstract: In-office needle arthroscopy (IONA) has been a readily available tool dating back to the 1990s, primarily for diagnostic purposes. This technique was not fully accepted and implemented because of significant limitations with the image quality and lack of ...

    Abstract In-office needle arthroscopy (IONA) has been a readily available tool dating back to the 1990s, primarily for diagnostic purposes. This technique was not fully accepted and implemented because of significant limitations with the image quality and lack of instrumentation available to simultaneously treat the identified pathologies. However, recent advancements in IONA technology have made it possible to perform arthroscopic procedures under local anesthesia in the office setting, which once required a full operating suite. IONA has revolutionized how we treat foot and ankle pathologies in our practice. IONA allows the patient to be an active participant in the procedure and provides an interactive experience. IONA can be used to treat a range of foot and ankle pathologies, including anterior ankle impingement, posterior ankle impingement, osteochondral lesions of the ankle joint, hallux rigidus, lateral ankle ligament repair, and tendoscopic treatment of Achilles, peroneal, and posterior tibial tendon disorders. Excellent outcomes with regard to subjective clinical outcomes, return to play times, and complications have been reported following IONA for these pathologies.
    MeSH term(s) Humans ; Ankle Joint/surgery ; Ankle ; Arthroscopy/methods ; Lateral Ligament, Ankle/surgery ; Joint Diseases/surgery
    Language English
    Publishing date 2023-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632528-2
    ISSN 1526-3231 ; 0749-8063
    ISSN (online) 1526-3231
    ISSN 0749-8063
    DOI 10.1016/j.arthro.2023.01.005
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  9. Article ; Online: Universal Masking to Prevent SARS-CoV-2 Transmission-The Time Is Now.

    Brooks, John T / Butler, Jay C / Redfield, Robert R

    JAMA

    2020  Volume 324, Issue 7, Page(s) 635–637

    MeSH term(s) COVID-19 ; Delivery of Health Care ; Health Personnel ; Humans ; Masks ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-14
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2020.13107
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  10. Article ; Online: Draft Genome Sequences of Bacillus licheniformis and Bacillus paralicheniformis Strains Isolated from Irish Skim Milk Powder.

    Lourenco, Antonio / Li, Fang / Quijada, Narciso M / Duffy, Geraldine / Tobin, John T / Butler, Francis / Jordan, Kieran / O'Brien, Triona

    Microbiology resource announcements

    2023  Volume 12, Issue 7, Page(s) e0013723

    Abstract: Nineteen Bacillus licheniformis strains and four strains of the closely related species Bacillus paralicheniformis were isolated from a variety of Irish medium-heat skim milk powders. The draft genome sequences of these 23 isolates provide valuable ... ...

    Abstract Nineteen Bacillus licheniformis strains and four strains of the closely related species Bacillus paralicheniformis were isolated from a variety of Irish medium-heat skim milk powders. The draft genome sequences of these 23 isolates provide valuable genetic data for research work relevant to dairy products and process development. The isolates are available at Teagasc.
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.00137-23
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