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  1. Article ; Online: Is One Exacerbation Enough to Modify Therapy in Chronic Obstructive Pulmonary Disease?

    Mannino, David M

    American journal of respiratory and critical care medicine

    2023  Volume 208, Issue 2, Page(s) 124–125

    MeSH term(s) Humans ; Hospitalization ; Disease Progression ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/physiopathology
    Language English
    Publishing date 2023-05-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202304-0783ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Is It Time to Abandon the Postbronchodilator Requirement in Defining Chronic Obstructive Pulmonary Disease?

    Mannino, David M

    American journal of respiratory and critical care medicine

    2022  Volume 206, Issue 5, Page(s) 522–524

    MeSH term(s) Cohort Studies ; Forced Expiratory Volume ; Humans ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/physiopathology
    Language English
    Publishing date 2022-05-09
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202204-0802ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Changing Definition and Perception of COPD.

    Mannino, David M

    Respiratory care

    2022  Volume 67, Issue 6, Page(s) 750–755

    Abstract: COPD remains one of the leading causes of death worldwide. The impact of smoking and air pollution remain important causative factors. Traditional classification of COPD includes the overlap of emphysema, chronic bronchitis and asthma. More recently the ... ...

    Abstract COPD remains one of the leading causes of death worldwide. The impact of smoking and air pollution remain important causative factors. Traditional classification of COPD includes the overlap of emphysema, chronic bronchitis and asthma. More recently the COPDGene definition includes the terms possible, probable and definite COPD. These are supported by findings from exposures, symptoms, spirometry and radiologic imaging. This new approach can lead to earlier diagnosis and modification of risk factors, earlier therapeutic intervention and improved treatments of established disease.
    MeSH term(s) Asthma/diagnosis ; Humans ; Perception ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/etiology ; Pulmonary Disease, Chronic Obstructive/therapy ; Pulmonary Emphysema ; Spirometry
    Language English
    Publishing date 2022-07-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.10059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Restricted spirometry through the lifespan.

    Mannino, David M

    The Lancet. Respiratory medicine

    2021  Volume 10, Issue 1, Page(s) 2–3

    MeSH term(s) Humans ; Longevity ; Spirometry
    Language English
    Publishing date 2021-11-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(21)00507-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: How I Review a Paper to Help Improve Citability and Impact.

    Mannino, David M

    Chest

    2021  Volume 160, Issue 6, Page(s) 2017–2018

    MeSH term(s) Editorial Policies ; Humans ; Manuscripts, Medical as Topic ; Peer Review, Research/methods ; Periodicals as Topic ; Publishing
    Language English
    Publishing date 2021-07-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.07.042
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  6. Article ; Online: Asthma, COPD and their overlap: coexistence or something more?

    Mannino, David M

    The European respiratory journal

    2021  Volume 58, Issue 5

    MeSH term(s) Asthma/diagnosis ; Asthma/epidemiology ; Forced Expiratory Volume ; Humans ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/diagnosis
    Language English
    Publishing date 2021-11-25
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01329-2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 292: Show issues

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  7. Article ; Online: Insights into the Spectrum of Chronic Lower Respiratory Disease: Low Lung Function Is Still Bad.

    Mannino, David M

    American journal of respiratory and critical care medicine

    2021  Volume 204, Issue 8, Page(s) 873–874

    MeSH term(s) Humans ; Lung/diagnostic imaging ; Respiration Disorders ; Respiratory Physiological Phenomena
    Language English
    Publishing date 2021-08-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202107-1637ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Spirometry in 2022: Is a Single Set of Prediction Equations for All the Best Path Forward?

    Mannino, David M / Townsend, Mary C

    American journal of respiratory and critical care medicine

    2023  Volume 207, Issue 6, Page(s) 659–661

    MeSH term(s) Humans ; Spirometry ; Respiratory Physiological Phenomena ; Lung
    Language English
    Publishing date 2023-01-04
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202211-2181ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Perspectives on Ensifentrine and Its Therapeutic Potential in the Treatment of COPD: Evidence to Date.

    Faruqi, Muhammad Asad / Khan, Malik M Khurram S / Mannino, David M

    International journal of chronic obstructive pulmonary disease

    2024  Volume 19, Page(s) 11–16

    Abstract: Ensifentrine is a novel inhalational phosphodiesterase (PDE)3 and PDE4 inhibitor which improves bronchodilation and decreases inflammatory markers by acting locally on the bronchial tissue, with minimal systemic effects. Both preclinical and clinical ... ...

    Abstract Ensifentrine is a novel inhalational phosphodiesterase (PDE)3 and PDE4 inhibitor which improves bronchodilation and decreases inflammatory markers by acting locally on the bronchial tissue, with minimal systemic effects. Both preclinical and clinical trials have demonstrated benefits of this therapy, including improvement in lung function and reduction in exacerbations. This therapy is currently under review by the US Food and Drug Administration with a decision expected in 2024.
    MeSH term(s) United States ; Humans ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Isoquinolines ; Pyrimidinones ; Bronchi
    Chemical Substances ensifentrine (3E3D8T1GIX) ; Isoquinolines ; Pyrimidinones
    Language English
    Publishing date 2024-01-03
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2212419-6
    ISSN 1178-2005 ; 1176-9106
    ISSN (online) 1178-2005
    ISSN 1176-9106
    DOI 10.2147/COPD.S385811
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Severity of Airflow Obstruction Based on FEV

    Backman, Helena / Vanfleteren, Lowie E G W / Mannino, David M / Ekström, Magnus

    American journal of respiratory and critical care medicine

    2024  

    Abstract: Rationale: According to GOLD, the ratio of FEV: Objective: To compare the STAR (FEV: Methods: Severity stages according to STAR and GOLD were applied to the multi-ethnic National Health and Nutrition Examination Survey (NHANES) 2007-2012 survey ... ...

    Abstract Rationale: According to GOLD, the ratio of FEV
    Objective: To compare the STAR (FEV
    Methods: Severity stages according to STAR and GOLD were applied to the multi-ethnic National Health and Nutrition Examination Survey (NHANES) 2007-2012 survey including ages 18-80 years, using post-bronchodilatory FEV
    Results: STAR versus GOLD severity staging of airflow obstruction showed similar associations with breathlessness and all-cause mortality, regardless of ethnicity/race. In those with airflow obstruction, the correlation between the two classification systems was 0.461 (p<0.001). STAR reclassified 59% of GOLD stage 2 as having mild airflow obstruction (STAR 1). STAR 1 was more clearly differentiated from the non-obstructive compared to GOLD stage 1 in terms of both breathlessness and mortality.
    Conclusions: FEV
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202310-1773OC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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