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  1. Book ; Audio / Video ; Thesis: Charakterisierung und Identifizierung von Membranproteinen auf der Ebene von Peptiden

    Meyer, Björn

    2007  

    Author's details von Björn Meyer
    Language German
    Size 1 CD-ROM, 12 cm
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 2008
    HBZ-ID HT015628788
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 MO 51 order for loan Magazin

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  2. Book ; Thesis: Die immunmodulatorischen Effekte von Katecholaminen auf Monozyten und dentritische Zellen unter den Bedingungen der Sepsis

    Meyer, Björn

    2012  

    Author's details vorgelegt von Björn Meyer
    Language German
    Size 111 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2012
    HBZ-ID HT018287946
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 E 747 order for loan Magazin

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  3. Book ; Thesis: Optimism and coping as predictors of adjustment after psychiatric hospitalization

    Meyer, Björn

    2001  

    Author's details by Björn Meyer
    Language English
    Size IX, 119 S. : graph. Darst.
    Publishing country United States
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Coral Gables, Fla., Univ. of Miami, Diss., 2001
    HBZ-ID HT014261978
    ISBN 0-493-00096-8 ; 978-0-493-00096-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 A 731 order for loan Magazin

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  4. Article ; Online: Uniquely conserved immunosuppressive viral exoribonucleases.

    Meyer, Bjoern / Ly, Hinh

    Oncotarget

    2017  Volume 8, Issue 4, Page(s) 5650–5651

    Keywords covid19
    Language English
    Publishing date 2017-01-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 2560162-3
    ISSN 1949-2553 ; 1949-2553
    ISSN (online) 1949-2553
    ISSN 1949-2553
    DOI 10.18632/oncotarget.14548
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: BiT age: A transcriptome-based aging clock near the theoretical limit of accuracy.

    Meyer, David H / Schumacher, Björn

    Aging cell

    2021  Volume 20, Issue 3, Page(s) e13320

    Abstract: Aging clocks dissociate biological from chronological age. The estimation of biological age is important for identifying gerontogenes and assessing environmental, nutritional, or therapeutic impacts on the aging process. Recently, methylation markers ... ...

    Abstract Aging clocks dissociate biological from chronological age. The estimation of biological age is important for identifying gerontogenes and assessing environmental, nutritional, or therapeutic impacts on the aging process. Recently, methylation markers were shown to allow estimation of biological age based on age-dependent somatic epigenetic alterations. However, DNA methylation is absent in some species such as Caenorhabditis elegans and it remains unclear whether and how the epigenetic clocks affect gene expression. Aging clocks based on transcriptomes have suffered from considerable variation in the data and relatively low accuracy. Here, we devised an approach that uses temporal scaling and binarization of C. elegans transcriptomes to define a gene set that predicts biological age with an accuracy that is close to the theoretical limit. Our model accurately predicts the longevity effects of diverse strains, treatments, and conditions. The involved genes support a role of specific transcription factors as well as innate immunity and neuronal signaling in the regulation of the aging process. We show that this binarized transcriptomic aging (BiT age) clock can also be applied to human age prediction with high accuracy. The BiT age clock could therefore find wide application in genetic, nutritional, environmental, and therapeutic interventions in the aging process.
    MeSH term(s) Aging/genetics ; Biological Clocks/genetics ; Fibroblasts/metabolism ; Humans ; Immunity, Innate/genetics ; Mutation/genetics ; Neurons/metabolism ; Signal Transduction ; Stress, Physiological/genetics ; Time Factors ; Transcriptome/genetics
    Language English
    Publishing date 2021-03-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2113083-8
    ISSN 1474-9726 ; 1474-9718
    ISSN (online) 1474-9726
    ISSN 1474-9718
    DOI 10.1111/acel.13320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6581: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Inheritance of paternal DNA damage by histone-mediated repair restriction.

    Wang, Siyao / Meyer, David H / Schumacher, Björn

    Nature

    2022  Volume 613, Issue 7943, Page(s) 365–374

    Abstract: How paternal exposure to ionizing radiation affects genetic inheritance and disease risk in the offspring has been a long-standing question in radiation biology. In humans, nearly 80% of transmitted mutations arise in the paternal ... ...

    Abstract How paternal exposure to ionizing radiation affects genetic inheritance and disease risk in the offspring has been a long-standing question in radiation biology. In humans, nearly 80% of transmitted mutations arise in the paternal germline
    MeSH term(s) Animals ; Humans ; Male ; Caenorhabditis elegans/embryology ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/radiation effects ; DNA Damage/radiation effects ; DNA Repair ; Genomic Instability/radiation effects ; Histones/metabolism ; Mutation ; Radiation, Ionizing ; Embryo Loss/genetics ; Female ; DNA Breaks, Double-Stranded/radiation effects ; DNA End-Joining Repair ; DNA Polymerase theta
    Chemical Substances Histones ; HPL-1 protein, C elegans
    Language English
    Publishing date 2022-12-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-022-05544-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 26: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MG 9: Show issues
    Zs.MO 244: Show issues

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  7. Article ; Online: Modern gold standard of cardiac output measurement - A simplified bedside measurement of individual oxygen uptake in the cath lab.

    Schmücker, Georg / Burgdorf, Christof / Blohm, Jan-Henrik / Bugno, Mathias / Meyer, Kathrin / Remppis, Bjoern Andrew

    Journal of basic and clinical physiology and pharmacology

    2022  Volume 33, Issue 5, Page(s) 639–644

    Abstract: Objectives: Cardiac output (CO) measurements employing the direct Fick principle represent the gold standard in right-sided heart catheterization (RHC). The current widespread approach in hemodynamic workup however uses the indirect Fick principle with ... ...

    Abstract Objectives: Cardiac output (CO) measurements employing the direct Fick principle represent the gold standard in right-sided heart catheterization (RHC). The current widespread approach in hemodynamic workup however uses the indirect Fick principle with assumed values for oxygen uptake (VO
    Methods: By means of a small and mobile metabolic cart assembled with widely used components of a standard spiroergometer, we performed bedside measurements of individual VO
    Results: In 28 of the 33 patients, VO
    Conclusions: The bedside measurement of VO
    MeSH term(s) Cardiac Catheterization ; Cardiac Output ; Humans ; Oxygen ; Oxygen Consumption
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2022-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1071737-7
    ISSN 2191-0286 ; 0792-6855 ; 0334-1534
    ISSN (online) 2191-0286
    ISSN 0792-6855 ; 0334-1534
    DOI 10.1515/jbcpp-2021-0293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article: Internetbasierte Interventionen bei arbeitsbezogenen psychischen Störungen

    Meyer, Björn

    (In: Kahl, Kai G.; Winter, Lotta (Ed.), Arbeitsplatzbezogene Psychotherapie. Intervention, Prävention und Rehabilitation. Mit einem Therapiemanual (S. 127-142). Stuttgart: Kohlhammer)

    2017  

    Abstract: Eine Übersicht zu internetbasierten Behandlungsansätzen, insbesondere bei arbeitsbezogenen psychischen Störungen und Beschwerden, wird vorgelegt. Behandelt werden folgende Punkte: (1) Vor- und Nachteile sowie Chancen und Risiken solcher Interventionen. ( ... ...

    Title translation Internet-based interventions for workplace-related mental disorders
    Series title In: Kahl, Kai G.; Winter, Lotta (Ed.), Arbeitsplatzbezogene Psychotherapie. Intervention, Prävention und Rehabilitation. Mit einem Therapiemanual (S. 127-142). Stuttgart: Kohlhammer
    Abstract Eine Übersicht zu internetbasierten Behandlungsansätzen, insbesondere bei arbeitsbezogenen psychischen Störungen und Beschwerden, wird vorgelegt. Behandelt werden folgende Punkte: (1) Vor- und Nachteile sowie Chancen und Risiken solcher Interventionen. (2) Begriffsklärung (internetbasierte Intervention, Internet-Intervention, Online-Therapie, E-Health Intervention, webbasierte Selbsthilfe, internetbasierte Behandlung). (3) Internetbasierte Fernbehandlungen. (4) "Stand-alone" Internet-Interventionen. (5) Stand der Wirksamkeitsforschung. (6) Studien bei berufstätigen Personen. (7) Meta-Analysen zur allgemeinen Wirksamkeit von Internet-Interventionen. (8) Beispiele von Internet-Interventionen (die Programme "deprexis", "reviga" und "velibra"). Ein abschließendes Fallbeispiel (39-jährige Patientin mit unipolarer Depression) illustriert die Anwendung von "deprexis".
    Keywords Berufskrankheiten ; Gesundheit am Arbeitsplatz ; Internetbasierte Therapie ; Major Depression ; Mental Disorders ; Occupational Health ; Online Therapy ; Psychische Störungen ; Work Related Illnesses
    Language German
    Document type Article
    Database PSYNDEX

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  9. Article ; Online: Substantial transmission of SARS-CoV-2 through casual contact in retail stores: Evidence from matched administrative microdata on card payments and testing.

    Johannesen, Niels / Tang-Andersen Martinello, Alessandro / Meyer, Bjørn Bjørnsson / Vestergaard, Emil Toft / Andersen, Asger Lau / Jensen, Thais Lærkholm

    Proceedings of the National Academy of Sciences of the United States of America

    2024  Volume 121, Issue 17, Page(s) e2317589121

    Abstract: This paper presents quasiexperimental evidence of Covid-19 transmission through casual contact between customers in retail stores. For a large sample of individuals in Denmark, we match card payment data, indicating exactly where and when each individual ...

    Abstract This paper presents quasiexperimental evidence of Covid-19 transmission through casual contact between customers in retail stores. For a large sample of individuals in Denmark, we match card payment data, indicating exactly where and when each individual made purchases, with Covid-19 test data, indicating when each individual was tested and whether the test was positive. The resulting dataset identifies more than 100,000 instances where an infected individual made a purchase in a store and, in each instance, allows us to track the infection dynamics of other individuals who made purchases in the same store around the same time. We estimate transmissions by comparing the infection rate of exposed customers, who made a purchase within 5 min of an infected individual, and nonexposed customers, who made a purchase in the same store 16 to 30 min before. We find that exposure to an infected individual in a store increases the infection rate by around 0.12 percentage points (
    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19 ; Consumer Behavior
    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2317589121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1148: Show issues Location:
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  10. Article: Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study).

    Abel, Marianne Hope / Totland, Torunn Holm / Holvik, Kristin / Brantsæter, Anne Lise / Krokstad, Steinar / Åsvold, Bjørn Olav / Meyer, Haakon E

    Food & nutrition research

    2024  Volume 68

    Abstract: Background: In Norway, there is a lack of knowledge about the iodine status in the general and older adult population, and there is no established national monitoring programme for iodine. Several studies have indicated that iodine deficiency is ... ...

    Abstract Background: In Norway, there is a lack of knowledge about the iodine status in the general and older adult population, and there is no established national monitoring programme for iodine. Several studies have indicated that iodine deficiency is prevalent in subgroups of the population. Salt iodisation is currently being considered as a measure to increase the population iodine status. In this cross-sectional study, the aim was to evaluate iodine status and determinants in the adult and older adult population in Mid-Norway, before salt iodisation is likely to be initiated.
    Methods: The study sample was a subsample of participants in the fourth wave of the population-based Trøndelag Health Study (HUNT4, 2017-2019) with available spot-urine samples. This subsample included participants with 25-64 years (
    Results: Median UIC was 97 µg/L (95% confidence interval [CI]: 92, 103) indicating borderline iodine deficiency at a group level. The median UIC increased with age, and iodine status was insufficient in participants below age 55 years (median 92 µg/L [95% CI: 85, 99]). Important determinants of UIC were habitual milk/yoghurt intake, daily supplement use and current use of thyroid medication, but not intake of lean or fatty fish. Risk of mild-to-moderate iodine deficiency was seen in those with a low intake of milk/yoghurt, no supplement use and who did not use thyroid medication. No group was identified as being at risk of iodine excess.
    Conclusion: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.
    Language English
    Publishing date 2024-04-01
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 2418338-6
    ISSN 1654-661X
    ISSN 1654-661X
    DOI 10.29219/fnr.v68.9761
    Database MEDical Literature Analysis and Retrieval System OnLINE

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