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Article ; Online: Correction: Dong et al. Identification of the Trace Components in BopuzongJian and

Dong, Zhuang / Liu, Mengting / Zhong, Xiaohong / Ou, Xiaoyong / Yun, Xuan / Wang, Mingcan / Ren, Shurui / Qing, Zhixing / Zeng, Jianguo

Molecules (Basel, Switzerland)

2024 Volume 29, Issue 6

Abstract: The article in question [ ... ]. ...

Abstract	The article in question [...].
Language	English
Publishing date	2024-03-13
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules29061268
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Article ; Online: Ganxiao Dong

Sunbin Huang / Guofu Wei / Hengsong Wang / Weixin Liu / Anne Bedos / Louis Deharveng / Mingyi Tian

Diversity, Vol 13, Iss 355, p

A Hotspot of Cave Biodiversity in Northern Guangxi, China

2021 Volume 355

Abstract: ... Ganxiao Dong harbours the richest cave fauna currently known in China. In total, 26 species of cave ...

Abstract	Located in the core zone of Mulun National Nature Reserve in northern Guangxi, the limestone cave Ganxiao Dong harbours the richest cave fauna currently known in China. In total, 26 species of cave invertebrates have been recognized so far, in spite of limited sampling efforts. Of them, 20 are troglobionts or stygobionts, including one snail, four millipedes, three spiders, one harvestman, three isopods, two springtails, two crickets, one non-glowing sticky worm, and three trechine beetles. Six other species are troglophiles. The most remarkable characteristic of this fauna is its high number of troglomorphic species, especially among millipedes, crickets and beetles.
Keywords	biodiversity ; cave ; hotspot ; Huanjiang ; Guangxi ; South China Karst ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Analysis of the Dong bao Ye as sacred landscape and its Putative therapeutic mechanisms.

Yang, Shiqi / Liu, Juanjuan / Winterbottom, Daniel

Health & place

2023 Volume 83, Page(s) 103102

Abstract: ... the sacred bao ye landscape of the Dong people of China as the research subject. By adopting the case study ...

Abstract	Humans have innately established close and profound ties with the, and through these relationships shaped many kinds of landscapes. Among these are sacred landscapes, which have drawn the attention of researchers due to their cultural significance. In the field of health geography, large-sized sacred regional landscapes are now the focus of studies for their therapeutic properties. However, few scholars have focused on small sacred landscape systems at the community level (constructed by local communities) or the physical and psycological health benefits that these landscapes offer to the local residents. These small-sized and widespread, but often hidden, sacred landscapes are closely tied to people's daily lives and work. They have evolved and grown over millennia to become critical sociocultural phenomena. This study takes the sacred bao ye landscape of the Dong people of China as the research subject. By adopting the case study approach, field research, semi-structured interviews, and textual analysis, it summarizes the types, geographical distribution, rituals and processes of bao ye as a sacred landscape of the Huanggang village in Guizhou Province, and concludes with an analysis of motivation and health benefits to the bao ye worship. In this paper we argue that bao ye is a sacred landscape system focusing on the healthy development of children, and constitutes a local belief developed in an isolated environment lacking medical resources, which remains in practice. The sacred landscape of bao ye offers a therapeutic environment, providing children with increased opportunities to engage with and build deep connections to nature. Thruogh this process children may develop a bond with nature that inspires them to protect nature on their own accord. We argue that bao ye offers an important case study for understanding the landscape-people-healing interactivity at the community level.
MeSH term(s)	Child ; Humans ; China ; Geography ; Health Status ; Motivation
Language	English
Publishing date	2023-08-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1262540-1
ISSN	1873-2054 ; 1353-8292
ISSN (online)	1873-2054
ISSN	1353-8292
DOI	10.1016/j.healthplace.2023.103102
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Article ; Online: Xiaoping Dong, China CDC's Chief Expert of Virology.

Chen, Yu / Hao, Peter / Liu, Nankun / Li, Zhenjun / Xi, Jingjing / Tan, Feng

China CDC weekly

2021 Volume 3, Issue 19, Page(s) 414–415

Language	English
Publishing date	2021-08-29
Publishing country	China
Document type	Journal Article
ISSN	2096-7071
ISSN (online)	2096-7071
DOI	10.46234/ccdcw2021.107
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Article: Study of the Antimicrobial Activity of the Chinese Dong Ethnic Minority Medicine, Madeng'ai.

Tang, Zhenrong / Zhao, Yannan / Zhang, Zaiqi / Yue, Huan / Wang, Dan / Liu, Shengchun / Tang, Hua

Evidence-based complementary and alternative medicine : eCAM

2022 Volume 2022, Page(s) 3678240

Abstract: ... multidrug-resistant infections are needed. The traditional Dong ethnic minority medicines have emerged ...

Abstract	The overuse of antibiotics has contributed to the emergence of multidrug-resistant bacteria, which poses a challenging task for clinical therapy. Thus, new agents with antibiotic efficacy against multidrug-resistant infections are needed. The traditional Dong ethnic minority medicines have emerged as a new source for prodrug selection. Among them, Madeng'ai (
Language	English
Publishing date	2022-08-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2022/3678240
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Zs.A 5995: Show issues

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Article ; Online: Comprehensive analyses of genetic diversities and population structure of the Guizhou Dong group based on 44 Y-markers.

Zhang, Hongling / Huang, Xiaolan / Jin, Xiaoye / Ren, Zheng / Wang, Qiyan / Yang, Meiqing / Xu, Ronglan / Yuan, Xiang / Yang, Daiquan / Liu, Hongyan / Shen, Wanyi / Zhang, Huiying / Que, Yangjie / Huang, Jiang

PeerJ

2023 Volume 11, Page(s) e16183

Abstract: ... the genetic distribution of Y-STRs in the Guizhou Dong population, provide reference data for forensic ... application, and explore the phylogenetic relationships between the Guizhou Dong population and ... other comparison populations.: Methods: Based on the allele profile of 44 Y-markers in the Guizhou Dong group ...

Abstract	Background: The non-recombining region of the human Y chromosome (NRY) is a strictly paternally inherited genetic marker and the best material to trace the paternal lineages of populations. Y chromosomal short tandem repeat (Y-STR) is characterized by high polymorphism and paternal inheritance pattern, so it has been widely used in forensic medicine and population genetic research. This study aims to understand the genetic distribution of Y-STRs in the Guizhou Dong population, provide reference data for forensic application, and explore the phylogenetic relationships between the Guizhou Dong population and other comparison populations. Methods: Based on the allele profile of 44 Y-markers in the Guizhou Dong group, we estimate their allele frequencies and haplotype frequencies. In addition, we also compare the forensic application efficiency of different Y-STR sets in the Guizhou Dong group. Finally, genetic relationships among Guizhou Dong and other reference populations are dissected by the multi-dimensional scaling and the phylogenetic tree. Results: A total of 393 alleles are observed in 312 Guizhou Dong individuals for these Y-markers, with allele frequencies ranging from 0.0032 to 0.9679. The haplotype diversity and discriminatory capacity for these Y-markers in the Guizhou Dong population are 0.99984 and 0.97440, respectively. The population genetic analyses of the Guizhou Dong group and other reference populations show that the Guizhou Dong group has the closest genetic relationship with the Hunan Dong population, and followed by the Guizhou Tujia population. Conclusions: In conclusion, these 44 Y-markers can be used as an effective tool for male differentiation in the Guizhou Dong group. The haplotype data in this study not only enrich the Y-STR data of different ethnic groups in China, but also have important significance for population genetics and forensic research.
MeSH term(s)	Humans ; Phylogeny ; Gene Frequency ; Genetics, Population ; Polymorphism, Genetic/genetics ; Ethnicity/genetics
Language	English
Publishing date	2023-09-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2703241-3
ISSN	2167-8359 ; 2167-8359
ISSN (online)	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.16183
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Article: Characterization of the Key Aroma Compounds in Dong Ding Oolong Tea by Application of the Sensomics Approach.

Wang, Daoliang / Wang, Cainan / Su, Weiying / Lin, Chih-Cheng / Liu, Wei / Liu, Yuan / Ni, Li / Liu, Zhibin

Foods (Basel, Switzerland)

2023 Volume 12, Issue 17

Abstract: The Dong Ding oolong tea (DDT), grown and produced in Taiwan, is widely appreciated for its unique ...

Abstract	The Dong Ding oolong tea (DDT), grown and produced in Taiwan, is widely appreciated for its unique flavor. Despite its popularity, research on the aroma components of DDT remains incomplete. To address this gap, this study employed a sensomics approach to comprehensively characterize the key aroma compounds in DDT. Firstly, sensory evaluation showed that DDT had a prominent caramel aroma. Subsequent analysis using gas chromatography-olfactory mass spectrometry (GC-O-MS) and comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC × GC-TOF-MS) identified a total of 23 aroma-active compounds in DDT. Notably, three pyrazine compounds with roasted notes, namely 2-ethyl-5-methylpyrazine, 2-ethyl-3,5-dimethylpyrazine, and 2,3-diethyl-5-methylpyrazine, along with seven floral- and fruit-smelling compounds, namely 6-methyl-5-hepten-2-one, 3,5-octadien-2-one, linalool, (
Language	English
Publishing date	2023-08-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12173158
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Article: Qi-Dong-Huo-Xue-Yin balances the immune microenvironment to protect against LPS induced acute lung injury.

Zhao, Tian / Wang, Le / Zhang, Yongjun / Ye, Wu / Liu, Juan / Wu, Haiyan / Wang, Fei / Tang, Tingyu / Li, Zhijun

Frontiers in pharmacology

2023 Volume 14, Page(s) 1200058

Abstract: ... of a traditional Chinese medicine, Qi-Dong-Huo-Xue-Yin (QD), in protecting against LPS induced acute lung injury in mouse models ...

Abstract	COVID-19 induces acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) and leads to severe immunological changes that threatens the lives of COVID-19 victims. Studies have shown that both the regulatory T cells and macrophages were deranged in COVID-19-induced ALI. Herbal drugs have long been utilized to adjust the immune microenvironment in ALI. However, the underlying mechanisms of herbal drug mediated ALI protection are largely unknown. This study aims to understand the cellular mechanism of a traditional Chinese medicine, Qi-Dong-Huo-Xue-Yin (QD), in protecting against LPS induced acute lung injury in mouse models. Our data showed that QD intrinsically promotes Foxp3 transcription via promoting acetylation of the Foxp3 promoter in CD4
Language	English
Publishing date	2023-05-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2023.1200058
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Article ; Online: Amino accelerators and antioxidants in sediments from the Dong Nai River System, Vietnam: Distribution and influential factors.

Jin, Ruihe / Li, Yue / Saito, Yoshiki / Wang, Zhanghua / Oanh Ta, Thi Kim / Nguyen, Van Lap / Yang, Jing / Liu, Min / Wu, Yan

Environmental research

2023 Volume 227, Page(s) 115712

Abstract: ... Os and five AAO transformation products (AAOTPs) in seventy-seven sediments from the Dong Nai ...

Abstract	Amino accelerators and antioxidants (AAL/Os) have become a suite of contaminants of emerging concern recently due to the accumulating evidence for their environmental occurrence and associated toxic potential. Nevertheless, data on sedimentary deposition of AAL/Os has remained scarce, particularly for regions beyond the North America. In the present study, we elucidated spatial distribution of fifteen AAL/Os and five AAO transformation products (AAOTPs) in seventy-seven sediments from the Dong Nai River System (DNRS), Vietnam. Total concentrations of AAL/Os (∑AAL/Os) ranged from 0.377 to 51.4 ng/g (median: 5.01 ng/g). 1,3-Diphenylguanidine and 4,4'-bis(1,1-dimethylbenzyl) diphenylamine were the two most prevalent congeners, both with detection frequencies >80%. Additionally, AAOTPs were quantifiable in 79% of the DNRS sediments with a median ∑AAOTPs at 2.19 ng/g, dominated by N, N'-diphenylbenzidine and 2-nitrodiphenylamine. Higher sediment-associated levels of AAL/Os and AAOTPs were spotted in downstream and the primary tributary of the DNRS compared to the upstream, implying their cumulative sedimentation towards the estuarine region. The distribution patterns of AAL/Os and AAOTPs across individual transects also demonstrated the influence of human activities (e.g., urbanization and agriculture), hydrodynamics, and decontamination by mangrove reserves. Meanwhile, characteristics of sediments, i.e., total organic carbon (TOC) content and grain sizes, exhibited significant correlations with the burdens of these compounds, indicating their preferential partitioning into the fine and TOC-rich matter. This research sheds light on environmental behavior of AAL/Os and AAOTPs beneath Asian aquatic system, and highlights the need for further evaluation of their impacts on the wildlife and public health.
MeSH term(s)	Humans ; Antioxidants ; Water Pollutants, Chemical/analysis ; Vietnam ; Rivers ; Agriculture ; Geologic Sediments ; Environmental Monitoring ; China
Chemical Substances	Antioxidants ; Water Pollutants, Chemical
Language	English
Publishing date	2023-03-16
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2023.115712
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Article ; Online: The Tian-Men-Dong decoction suppresses the tumour-infiltrating G-MDSCs via IL-1β-mediated signalling in lung cancer.

Su, Lin / Zhang, Fei / Liu, Ming-Xi / Li, Hong / Li, Qiang / Zhu, Yang-Zhuangzhuang / Hou, Yi-Fei / Chen, Xiao / Wang, Xiao-Yu / Qian, Chun-Mei / Yao, Chao / Wang, Li-Xin / Jiao, Xiao-Ning / Zhu, Xian-Dan / Xu, Zi-Hang / Zou, Chun-Pu

Journal of ethnopharmacology

2023 Volume 313, Page(s) 116491

Abstract: Ethnopharmacological relevance: The traditional Chinese medicine (TCM) Tian-Men-Dong decoction (TD ...

Abstract	Ethnopharmacological relevance: The traditional Chinese medicine (TCM) Tian-Men-Dong decoction (TD) has been able to effectively treat lung cancer in China for thousands of years. TD improves the quality of life in lung cancer patients by promoting nourishment of yin and reducing dryness, clearing the lung and removing toxins. Pharmacological studies show that TD contains active antitumour ingredients, but its underlying mechanism remains unknown. Aim of the study: This study aims at exploring potential mechanisms of TD in the treatment of lung cancer by regulating granulocytic-myeloid-derived suppressor cells (G-MDSCs). Materials and methods: An orthotopic lung cancer mouse model was generated by intrapulmonary injection with LLC-luciferase cells in immunocompetent C57BL/6 mice or immunodeficient nude mice. TD/saline was orally administered once to the model mice daily for 4 weeks. Live imaging was conducted to monitor tumour growth. Immune profiles were detected by flow cytometry. H&E and ELISA were applied to test the cytotoxicity of the TD treatment. RT-qPCR and western blotting were performed to detect apoptosis-related proteins in G-MDSCs. A neutralizing antibody (anti-Ly6G) was utilized to exhaust the G-MDSCs via intraperitoneal injection. G-MDSCs were adoptively transferred from wild-type tumour-bearing mice. Immunofluorescence, TUNEL and Annexin V/PI staining were conducted to analyse apoptosis-related markers. A coculture assay of purified MDSCs and T cells labelled with CFSE was performed to test the immunosuppressive activity of MDSCs. The presence of TD/IL-1β/TD + IL-1β in purified G-MDSCs cocultured with the LLC system was used for ex vivo experiments to detect IL-1β-mediated apoptosis of G-MDSCs. Results: TD prolonged the survival of immune competent C57BL/6 mice in an orthotopic lung cancer model, but did not have the same effect in immunodeficient nude mice, indicating that its antitumour properties of TD are exerted by regulating immunity. TD induced G-MDSC apoptosis via the IL-1β-mediated NF-κB signalling cascade leading to effectively weaken the immunosuppressive activity of G-MDSCs and promote CD8 Conclusion: This study reveals for the first time that TD, a classic TCM prescription, is able to regulate G-MDSC activity and trigger its apoptosis via the IL-1β-mediated NF-κB signalling pathway, reshaping the tumour microenvironment and demonstrating antitumour effects. These findings provide a scientific foundation the clinical treatment of lung cancer with TD.
MeSH term(s)	Mice ; Animals ; Myeloid-Derived Suppressor Cells ; Mice, Nude ; NF-kappa B/metabolism ; Quality of Life ; Mice, Inbred C57BL ; Lung Neoplasms/metabolism ; Immunosuppressive Agents/pharmacology ; Tumor Microenvironment
Chemical Substances	NF-kappa B ; Immunosuppressive Agents
Language	English
Publishing date	2023-04-16
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.116491
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