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  1. Book ; Online: Historical Background of Wang Yang-ming’s Philosophy of Mind

    Dong, Ping

    From the Perspective of his Life Story

    2020  

    Author's details by Ping Dong
    Keywords Philosophy, Asian ; Oriental literature ; Asien ; Philosophie ; Geschichte ; Wang, Yangming ; Philosophy of Mind ; Zeithintergrund
    Subject Historischer Hintergrund ; Geschichtlicher Hintergrund ; Mind ; Geist ; Philosophie des Geistes ; Philosophieren
    Subject code 181
    Language English
    Size 1 Online-Ressource (X, 199 p. 1 illus)
    Edition 1st ed. 2020
    Publisher Springer Singapore ; Imprint: Springer
    Publishing place Singapore
    Document type Book ; Online
    HBZ-ID HT020468204
    ISBN 978-981-15-3036-4 ; 9789811530357 ; 9789811530371 ; 9789811530388 ; 981-15-3036-X ; 9811530351 ; 9811530378 ; 9811530386
    DOI 10.1007/978-981-15-3036-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Pd/Ming-Phos-Catalyzed Asymmetric Three-Component Arylsilylation of

    Yang, Bin / Cao, Kangning / Zhao, Guofeng / Yang, Junfeng / Zhang, Junliang

    Journal of the American Chemical Society

    2022  Volume 144, Issue 34, Page(s) 15468–15474

    Abstract: A Pd-catalyzed enantioselective three-component reaction ... ...

    Abstract A Pd-catalyzed enantioselective three-component reaction of
    MeSH term(s) Catalysis ; Esters ; Palladium ; Silanes ; Stereoisomerism
    Chemical Substances Esters ; Silanes ; Palladium (5TWQ1V240M)
    Language English
    Publishing date 2022-08-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.2c07037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Xiao-Xu-Ming

    Wang, Yue-Hua / Yang, Ying-Lin / Cheng, Xiao / Zhang, Jun / Li, Wan / Du, Guan-Hua

    Neural regeneration research

    2018  Volume 14, Issue 3, Page(s) 470–479

    Abstract: Xiao-Xu-Ming decoction has been widely used to treat stroke and sequelae of stroke. We have ... previously shown that the active fractions of Xiao-Xu-Ming decoction attenuate cerebral ischemic injury ... However, the global protein profile and signaling conduction pathways regulated by Xiao-Xu-Ming decoction are still ...

    Abstract Xiao-Xu-Ming decoction has been widely used to treat stroke and sequelae of stroke. We have previously shown that the active fractions of Xiao-Xu-Ming decoction attenuate cerebral ischemic injury. However, the global protein profile and signaling conduction pathways regulated by Xiao-Xu-Ming decoction are still unclear. This study established a two-vessel occlusion rat model by bilateral common carotid artery occlusion. Rats were intragastrically administered 50 or 150 mg/kg Xiao-Xu-Ming decoction for 4 consecutive weeks. Learning and memory abilities were measured with Morris water maze. Motor ability was detected with prehensile test. Coordination ability was examined using the inclined screen test. Neuronal plasticity was observed by immunofluorescent staining. Differentially expressed proteins of rat hippocampus were analyzed by label-free quantitative proteomics. Real time-polymerase chain reaction and western blot assay were used to identify the changes in proteins. Results showed that Xiao-Xu-Ming decoction dramatically alleviated learning and memory deficits, and motor and coordination dysfunction, and increased the expression of microtubule-associated protein 2. Xiao-Xu-Ming decoction extract remarkably decreased 13 upregulated proteins and increased 39 downregulated proteins. The regulated proteins were mainly involved in oxidation reduction process, intracellular signaling cascade process, and protein catabolic process. The signaling pathways were mainly involved in ubiquitin mediated proteolysis and the phosphatidylinositol signaling system. Furthermore, there was an interaction among Rab2a, Ptpn1, Ppm1e, Cdk18, Gorasp2, Eps15, Capza2, Syngap1 and Mt-nd1. Protein analyses confirmed the changes in expression of MT-ND1. The current findings provide new insights into the molecular mechanisms of Xiao-Xu-Ming decoction extract's effects on chronic cerebral hypoperfusion.
    Language English
    Publishing date 2018-12-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.245471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Multi-analytical approach to the mural painting from an ancient tomb of Ming Dynasty in Jiyuan, China: Characterization of materials and techniques.

    Liu, Zhaojun / Yang, Rui / Wang, Weihao / Xu, Wenzhong / Zhang, Mengzhu

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2022  Volume 279, Page(s) 121419

    Abstract: The pigments, surface deposition, preparatory layer and support from a mural painting tomb of Ming ... significant information on the materials and techniques used to build mural painting tomb in Ming Dynasty ...

    Abstract The pigments, surface deposition, preparatory layer and support from a mural painting tomb of Ming Dynasty (1368-1644 CE) were first time analyzed by micro-Raman, Fourier-transform Infrared (FT-IR), X-ray diffraction (XRD), scanning electron microscope with energy-dispersive X-ray microanalysis (SEM-EDX), thermogravimetry and differential scanning calorimetry (TG-DSC) to reach a better understanding of the composition of the materials and the techniques adopted. All the pigments were identified, including hematite, cinnabar, malachite, yellow ochre, calcite and carbon black. The preparatory layer was found to be prepared by fine lime mortar with cotton fiber inside. The crystalline depositions on the mural painting were identified as calcite and dolomite originated from the lime-based preparatory layer. The support was found to be constructed with sticky rice lime mortar with several kinds of additives. The original lime stone was demonstrated to be magnesium-rich and the carbonization results were also discussed. These results revealed significant information on the materials and techniques used to build mural painting tomb in Ming Dynasty. This will benefit the further restoration and conservation works and also provide a methodology solution for the scientific analysis of ancient tomb mural paintings.
    Language English
    Publishing date 2022-05-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2022.121419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: In vitro and in vivo anti-osteoarthritis effects of tradition Chinese prescription Ji-Ming-San.

    Hsieh, Cheng-Yang / Wang, Ching-Chiung / Tayo, Lemmuel L / Deng, Shun-Xin / Tsai, Po-Wei / Lee, Chia-Jung

    Journal of ethnopharmacology

    2022  Volume 305, Page(s) 116084

    Abstract: Ethnopharmacological relevance: Ji-Ming-Shan (JMS) is a traditional herbal prescription consisting ...

    Abstract Ethnopharmacological relevance: Ji-Ming-Shan (JMS) is a traditional herbal prescription consisting of seven herbs including Areca cathechu Burm.f., Citrus reticulata Blanco, Chaenomeles speciosa (Sweet) Nakai, Euodia ruticarpa (A. Juss.) Benth., Perilla frutescens (L.) Britton, Zingiber officinale Roscoe, Platycodon grandiflorus (Jacq.). It was first recorded during the Song dynasty and has been used extensively for protection against rheumatism, treatment of swelling of tendons, relief from foot pain, gout and diuresis and other forms of inflammation.
    Aim of the study: The aim of this study is to evaluate the anti-inflammatory and anti-osteoarthritis activity of JMS extracts with the use of different cell lines (RAW 264.7 cells, SW1353 cells and primary cultured rat chondrocytes). MIA-induced rat animal models were used to assess the anti-osteoarthritis activity of the extract.
    Materials and methods: This study investigated the anti-inflammatory activity of JMS-95E on LPS-induced RAW 264.7 macrophages and IL-1β-stimulated chondrocytes. For the in vivo study, male Wistar rats were used and they were randomly assigned in different groups: blank, control, positive control and three different JMS-95E treatment groups (200, 400, 800 mg/kg/d). Paw edema, hind-limb weight bearing, serum inflammatory cytokines including hematoxylin and eosin (HE) staining experiments were used to assess the efficacy of the extract in the rat model.
    Result: JMS 95% ethanol extract (JMS-95E, marker substance: narirutin (5.10 mg/g) and hesperidin (11.33 mg/g) has been identified in the extract using high pressure liquid chromatography. For in vitro assays, JMS-95E did not exhibit cytotoxicity and was able to downregulate the protein expression of iNOS, COX-2 and MMP-13. The production of inflammatory mediators such as NO and PGE
    Conclusion: JMS-95E inhibited the inflammatory pathway leading to the production or expression levels of NO, iNOS, COX-2 and PGE
    MeSH term(s) Animals ; Male ; Rats ; Anti-Inflammatory Agents/adverse effects ; Carrageenan ; Cyclooxygenase 2/metabolism ; Disease Models, Animal ; Edema/chemically induced ; Edema/drug therapy ; Edema/prevention & control ; Inflammation/drug therapy ; Matrix Metalloproteinase 13 ; Osteoarthritis/drug therapy ; Pain/drug therapy ; Plant Extracts/adverse effects ; Rats, Sprague-Dawley ; Rats, Wistar ; Drugs, Chinese Herbal/pharmacology
    Chemical Substances Anti-Inflammatory Agents ; Carrageenan (9000-07-1) ; Cyclooxygenase 2 (EC 1.14.99.1) ; Matrix Metalloproteinase 13 (EC 3.4.24.-) ; Plant Extracts ; Drugs, Chinese Herbal
    Language English
    Publishing date 2022-12-27
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2022.116084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Erratum: SILVIA FABRIZI, WAN-GANG LIU, MING BAI, XING-KE YANG amp; DIRK AHRENS (2021) A monograph of the genus Maladera Mulsant amp; Rey, 1871 of China (Coleoptera: Scarabaeidae: Melolonthinae: Sericini). Zootaxa, 4922 (1): 001400.

    Fabrizi, Silvia / Liu, Wan-Gang / Bai, Ming / Yang, Xing-Ke / Ahrens, Dirk

    Zootaxa

    2022  Volume 5169, Issue 6, Page(s) 600

    Language English
    Publishing date 2022-08-03
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5169.6.7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Application of Improved Particle Swarm Optimization SVM in Water Quality Evaluation of Ming Cui Lake

    Zunyang Zhang / Cheng Yang / Qiao Qiao / Xuesheng Li / Fuping Wang / Chengcheng Li

    Sustainability, Vol 15, Iss 9835, p

    2023  Volume 9835

    Abstract: ... In this paper, 480 sets of data from Ming Cui Lake from 2014 to 2022 are taken as the research object, and ...

    Abstract Water quality directly determines our living environment. In order to establish a more scientific and reasonable water quality evaluation model, it needs a lot of data support, but it will lead to a large increase in the calculation time of the evaluation model. This paper proposes an improved particle swarm optimization SVM model (CPOS-SVM) to solve this problem. In this paper, the Pareto optimal solution concept is used to sparsely process the training set, which can ensure that the number of training sets is reduced without loss of data characteristics, thus reducing the training time. In order to solve the problem of the kernel parameter g and penalty factor c on the SVM algorithm, which affects the accuracy of the SVM model but it is difficult to select why, a particle swarm optimization algorithm is used in this paper to optimize the kernel parameter and penalty factor and improve the accuracy of the model. In this paper, 480 sets of data from Ming Cui Lake from 2014 to 2022 are taken as the research object, and examples are analyzed in MATLAB 2020a. The results show that the training time of the CPOS-SVM model can be completed within 2 s and does not increase with the increase of data volume. Meanwhile, by comparing the SVM model, POS-SVM model, and POS-BP model, training time increases dramatically with the amount of data. The accuracy of the POS-SVM model is the highest, and the accuracy of the CPOS-SVM model is basically consistent with that of the POS-SVM, reaching 94%, while the accuracy of the SVM model and the POS-BP model are slightly worse. This indicates that the CPOS-SVM model has good application value in water quality evaluation.
    Keywords Pareto optimal solution ; support vector machine ; particle swarm optimization algorithm ; water quality evaluation ; water treatment ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 310
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Network pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing loss.

    Yang, Yi-Fang / Yan, Xi-Rui / Wu, Rui-Xin / Li, Ning / Chu, Min / Dong, Yang / Fu, Shu-Ping / Shi, Jian-Rong / Liu, Qing

    Pharmaceutical biology

    2022  Volume 60, Issue 1, Page(s) 1478–1490

    Abstract: Context: Yi-Qi Cong-Ming (YQCM) decoction has been widely used to prevent age-related hearing loss ...

    Abstract Context: Yi-Qi Cong-Ming (YQCM) decoction has been widely used to prevent age-related hearing loss (ARHL), the most prevalent neurodegenerative disease in the elderly.
    Objective: To explore the mechanism of YQCM decoction in the treatment of ARHL.
    Materials and methods: The chemical constituents of YQCM were screened from the Traditional Chinese Medicine Systems Pharmacology Database. Potential targets of YQCM against ARHL were predicted by DrugBank, GeneCards, and OMIM database. Protein-protein network and enrichment analysis were used for exploring possible molecular mechanisms. Molecular docking and an
    Results: The main compounds have good affinities with hub targets, especially AKT1, PTGS2, and CASP3. GO and KEGG analysis showed that the main biological process and key targets were related to negative regulation of the apoptotic process. H
    Conclusions: Our study suggested that YQCM prevents ARHL by modulating the apoptosis process in auditory hair cells. Moreover, this study proved that bioinformatics analysis combined with molecular docking and cell model is a promising method to explore other possible pharmacological interventions of ARHL.
    MeSH term(s) Aged ; Caspase 3 ; Drugs, Chinese Herbal/therapeutic use ; Hearing Loss/drug therapy ; Humans ; Hydrogen Peroxide/toxicity ; Medicine, Chinese Traditional/methods ; Molecular Docking Simulation ; Network Pharmacology ; Neurodegenerative Diseases/drug therapy
    Chemical Substances Drugs, Chinese Herbal ; Hydrogen Peroxide (BBX060AN9V) ; Caspase 3 (EC 3.4.22.-)
    Language English
    Publishing date 2022-08-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440131-9
    ISSN 1744-5116 ; 1388-0209
    ISSN (online) 1744-5116
    ISSN 1388-0209
    DOI 10.1080/13880209.2022.2101671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation.

    Liu, Nannan / Liu, Chengdi / Yang, Yujiao / Ma, Guodong / Wei, Guangyi / Liu, Shan / Kong, Linglei / Du, Guanhua

    Pharmacological research

    2021  Volume 169, Page(s) 105650

    Abstract: ... Our previous experiments demonstrated that the Xiao-Xu-Ming decoction effective components group (XXMD ...

    Abstract Stroke is one of the leading causes of death worldwide. Hemorrhagic transformation (HT) is a common serious complication of ischemic stroke (IS) and is related to poor prognosis. Hyperglycemia after stroke is associated with the occurrence of HT and seriously affects the clinical treatment of stroke. Our previous experiments demonstrated that the Xiao-Xu-Ming decoction effective components group (XXMD), which is a Chinese medicine formula reconstituted by active ingredients, has multiple pharmacological effects in the treatment of IS. However, the effects of XXMD on HT after IS remain unclear. Thus, we investigated the preventive effects of XXMD on hyperglycemia-induced HT and further explored the underlying mechanism. Acute hyperglycemia combined with the electrocoagulation cerebral ischemia model was used to establish the HT model. XXMD (37.5, 75, 150 mg/kg/d) was given by gavage for 5 days. Network pharmacology was used to predict potential targets and pathways of XXMD in HT occurrence, and further studies confirmed the related targets. The results showed that hyperglycemia aggravated neurological deficits and blood-brain barrier (BBB) disruption, leading to intracerebral hemorrhage. Pretreatment with XXMD improved neurological function and BBB integrity and inhibited HT occurrence. Network pharmacology revealed that AGE-RAGE-mediated neuroinflammation may be associated with hyperglycemia-induced HT. Further studies confirmed that hyperglycemia activated the AGE-RAGE signaling pathway, increased the expression of HMGB1, TLR4 and p-p65, and induced the release of inflammatory factors and neutrophil infiltration, leading to HT. XXMD could inhibit AGE-RAGE-mediated neuroinflammation. These findings indicated that pretreatment with XXMD alleviated hyperglycemia-induced HT, which may be associated with the inhibition of AGE-RAGE-mediated neuroinflammation. Therefore, XXMD may be a potential therapeutic drug for HT.
    MeSH term(s) Animals ; Brain Ischemia/complications ; Cerebral Hemorrhage/drug therapy ; Cerebral Hemorrhage/prevention & control ; Drugs, Chinese Herbal/therapeutic use ; Hyperglycemia/complications ; Hyperglycemia/drug therapy ; Male ; Network Pharmacology/methods ; Neuroinflammatory Diseases/drug therapy ; Neuroinflammatory Diseases/prevention & control ; Rats ; Rats, Sprague-Dawley ; Receptor for Advanced Glycation End Products/metabolism ; Receptor for Advanced Glycation End Products/physiology
    Chemical Substances Drugs, Chinese Herbal ; Receptor for Advanced Glycation End Products ; xiao-xu-ming
    Language English
    Publishing date 2021-05-05
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1003347-6
    ISSN 1096-1186 ; 0031-6989 ; 1043-6618
    ISSN (online) 1096-1186
    ISSN 0031-6989 ; 1043-6618
    DOI 10.1016/j.phrs.2021.105650
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Chronopharmacology of diuresis via metabolic profiling and key biomarker discovery of the traditional Chinese prescription Ji-Ming-San using tandem mass spectrometry in rat models.

    Hsieh, Cheng-Yang / Tsai, Po-Wei / Tomioka, Yoshihisa / Matsumoto, Yotaro / Akiyama, Yasutoshi / Wang, Ching-Chiung / Tayo, Lemmuel L / Lee, Chia-Jung

    Phytomedicine : international journal of phytotherapy and phytopharmacology

    2023  Volume 124, Page(s) 155260

    Abstract: Background: Ji-Ming-Shan (JMS) is a traditional prescription used for patients with rheumatism ...

    Abstract Background: Ji-Ming-Shan (JMS) is a traditional prescription used for patients with rheumatism, tendons swelling, relief of foot pain, athlete's foot, diuresis, gout. Although many studies have investigated the active compounds in each herb, the functional mechanism behind its therapeutic effect remains unclear.
    Study design: Metabolic cages for sample collection. The serum components obtained from the experimental animals were analyzed using LC-MS/MS. Furthermore, cross-analysis using the software MetaboAnalyst and Venn diagrams were used to investigate chronopharmacology of JMS in the animal models.
    Purpose: The aim of this study is to analyze the diuretic effects of JMS and to explore their chronopharmacology involved in organ regulation through four-quarter periods from serum samples of rat models.
    Methods: Metabolic cages were used for collecting the urine samples and PocketChem UA PU-4010, Fuji DRI-CHEM 800 were used to examine the urine biochemical parameters. The serum components were identified through ultra-performance liquid chromatography-quadrupole time-of-flight (UPLC-Q-TOF) with a new developed method. Cross analysis, Venn diagram, MetaboAnalyst were used to investigate the key biomarker and major metabolism route with the oral administration of the drug.
    Result: JMS significantly changed the 6 h urine volume with no observed kidney toxicity. Urine pH value ranges from 7.0 to 7.5. The chronopharmacology of JMS diuresis activity were 0-6 and 6-12 groups. UPLC-Q-TOF analyses identified 243 metabolites which were determined in positive mode and negative mode respectively. With cross analysis in the Venn diagram, one key biomarker naringenin-7-O-glucoside has been identified. Major metabolic pathways such as 1: Glycerophospholipid metabolism, 2: Primary bile acid biosynthesis, 3: Sphingolipid metabolism, 4: Riboflavin metabolism, 5: Linoleic acid metabolism, 6: Butanoate metabolism.
    Conclusion: JMS significantly changed the urine output of animals in the 0-6 and 6-12 groups. No change in urine pH was observed and also kidney toxicity. A new UPLC-Q-TOF method was developed for the detection of the metabolites of JMS after oral administration. The cross analysis with Venn diagram and identified the key biomarker of JMS namely naringenin-7-O-glucoside. The results showed that six major pathways are involved in the gastrointestinal system and the liver. This study demonstrated the capability of JMS prescription in the regulation of diuresis and identified a key biomarker that is responsible for its therapeutic effect.
    MeSH term(s) Rats ; Humans ; Animals ; Tandem Mass Spectrometry/methods ; Rats, Sprague-Dawley ; Chromatography, Liquid ; Chromatography, High Pressure Liquid/methods ; Drugs, Chinese Herbal/analysis ; Diuresis ; Biomarkers ; China
    Chemical Substances Drugs, Chinese Herbal ; Biomarkers
    Language English
    Publishing date 2023-12-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1205240-1
    ISSN 1618-095X ; 0944-7113
    ISSN (online) 1618-095X
    ISSN 0944-7113
    DOI 10.1016/j.phymed.2023.155260
    Database MEDical Literature Analysis and Retrieval System OnLINE

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