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Article ; Online: Uncontrolled vaping and restraint strategies: A qualitative study.

Whitesell, Callie / Blount, Thomas H / Alton Dailey, Susan / Hall, Marissa G / Ribisl, Kurt M / Sheeran, Paschal / Kalan, Mohammad Ebrahimi / Brewer, Noel T

Social science & medicine (1982)

2024 Volume 349, Page(s) 116900

Abstract: Introduction: Little is known about uncontrolled vaping, defined as vaping more than the user prefers. We sought to understand e-cigarette users' experiences with uncontrolled vaping and how they restrain their vaping.: Methods: Participants were 24 ... ...

Abstract	Introduction: Little is known about uncontrolled vaping, defined as vaping more than the user prefers. We sought to understand e-cigarette users' experiences with uncontrolled vaping and how they restrain their vaping. Methods: Participants were 24 US adult e-cigarette users recruited in 2021. We conducted semi-structured qualitative interviews about uncontrolled vaping and restraint strategies and analyzed findings based on behavioral categories described in the Process Model of Self-Control. Results: While most participants (21 of 24) described experiences of uncontrolled vaping, some expressed ambivalence about how much they vaped. To restrain vaping, willpower was rarely used and was not perceived as effective. Distraction, deployment of attention away from the urge to vape, and reappraisal, thinking differently about vaping such as reminding oneself of health consequences, were common and helped some participants limit use in the moment of wanting to vape. Participants described using both situation selection, choosing to be in situations where e-cigarette use was less possible, and situation modification, modifying their circumstances to restrict opportunities to vape. Discussion: Uncontrolled vaping is not yet a well-defined concept for many e-cigarette users. E-cigarette users employed proactive situational strategies that required planning ahead to restrain use and found these strategies more effective compared to reactive strategies. Tobacco control programs and interventions should consider leveraging restraint strategies that people who vape are naturally using and perceive to be effective.
Language	English
Publishing date	2024-04-18
Publishing country	England
Document type	Journal Article
ZDB-ID	4766-1
ISSN	1873-5347 ; 0037-7856 ; 0277-9536
ISSN (online)	1873-5347
ISSN	0037-7856 ; 0277-9536
DOI	10.1016/j.socscimed.2024.116900
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Article: Amoxicillin-clavulanate induced DRESS syndrome masquerading as red man syndrome.

Jafry, Ali H / Nimri, Jena / Akhtar, Khawaja H / Qureshi, Saleem / Bray-Hall, Susan

Journal of family medicine and primary care

2022 Volume 11, Issue 7, Page(s) 3992–3995

Abstract: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe drug-induced hypersensitivity reaction carrying a mortality rate of up to 10%. We present a rare case of DRESS syndrome induced by amoxicillin-clavulanate, initially ... ...

Abstract	Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe drug-induced hypersensitivity reaction carrying a mortality rate of up to 10%. We present a rare case of DRESS syndrome induced by amoxicillin-clavulanate, initially masquerading as red man syndrome. A 32-year-old male was admitted with flu-like symptoms and a maculopapular rash on the trunk and face that was exacerbated with vancomycin infusion, concerning for red man syndrome. He was receiving systemic antibiotics (vancomycin, ceftriaxone, and metronidazole) for infective endocarditis and previously took amoxicillin-clavulanate for a dental abscess. Despite the discontinuation of vancomycin, the exanthem continued to worsen, extending to involve >50% of his body surface area. Eosinophilia, hepatosplenomegaly, and acute kidney and liver injuries prompted consideration of DRESS syndrome. All antibiotics were discontinued, and systemic glucocorticoids were initiated. Punch biopsy revealed interface dermatitis with eosinophilic infiltrates; a high RegiSCAR score confirmed the diagnosis of DRESS. Amoxicillin-clavulanate was flagged as a severe allergy and deemed the culprit owing to the timing of exposure and personal/family history of hypersensitivity.
Language	English
Publishing date	2022-07-22
Publishing country	India
Document type	Case Reports
ZDB-ID	2735275-4
ISSN	2278-7135 ; 2249-4863
ISSN (online)	2278-7135
ISSN	2249-4863
DOI	10.4103/jfmpc.jfmpc_2073_21
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Article ; Online: Assessing remission in major depressive disorder using a functional-structural data fusion pipeline: A CAN-BIND-1 study.

Ayyash, Sondos / Davis, Andrew D / Alders, Gésine L / MacQueen, Glenda / Strother, Stephen C / Hassel, Stefanie / Zamyadi, Mojdeh / Arnott, Stephen R / Harris, Jacqueline K / Lam, Raymond W / Milev, Roumen / Müller, Daniel J / Kennedy, Sidney H / Rotzinger, Susan / Frey, Benicio N / Minuzzi, Luciano / Hall, Geoffrey B

IBRO neuroscience reports

2024 Volume 16, Page(s) 135–146

Abstract: Neural network-level changes underlying symptom remission in major depressive disorder (MDD) are often studied from a single perspective. Multimodal approaches to assess neuropsychiatric disorders are evolving, as they offer richer information about ... ...

Abstract	Neural network-level changes underlying symptom remission in major depressive disorder (MDD) are often studied from a single perspective. Multimodal approaches to assess neuropsychiatric disorders are evolving, as they offer richer information about brain networks. A
Language	English
Publishing date	2024-01-04
Publishing country	Netherlands
Document type	Journal Article
ISSN	2667-2421
ISSN (online)	2667-2421
DOI	10.1016/j.ibneur.2023.12.011
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Article: Attention Deployment to the Eye Region of Emotional Faces among Adolescents with and without Social Anxiety Disorder.

Capriola-Hall, Nicole N / Ollendick, Thomas H / White, Susan W

Cognitive therapy and research

2020 Volume 45, Issue 3, Page(s) 456–467

Abstract: Background: Avoidance of the eye region, especially of faces showing anger, may maintain social anxiety symptoms by negatively reinforcing expectations and fears associated with social situations. Eye-tracking research, however, has yet to explicitly ... ...

Abstract	Background: Avoidance of the eye region, especially of faces showing anger, may maintain social anxiety symptoms by negatively reinforcing expectations and fears associated with social situations. Eye-tracking research, however, has yet to explicitly examine differences in attention allocation to the eye region of emotional faces among adolescents with social anxiety disorder (SAD). Methods: Gaze patterns were explored in a sample of youth with and without SAD matched on age and sex. Results: Adolescents with SAD were quicker to fixate, and maintained their initial gaze longer, to the eye region, regardless of emotion, relative to teens without SAD. Group-level differences also emerged for initial fixation duration directed to the eye region of angry faces (when compared with happy faces). Conclusions: These findings suggest that vigilance to the eye region of faces, especially angry faces, (when compared with happy faces) is characteristic of adolescents with SAD. Adolescents with SAD seem drawn to the eye region, more so than teens without SAD.
Language	English
Publishing date	2020-10-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	282402-4
ISSN	1573-2819 ; 0147-5916
ISSN (online)	1573-2819
ISSN	0147-5916
DOI	10.1007/s10608-020-10169-2
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Article ; Online: Nonmetropolitan COVID-19 Incidence and Mortality Rates Surpassed Metropolitan Rates Within the First 24 Weeks of the Pandemic Declaration: United States, March 1-October 18, 2020.

Matthews, Kevin A / Ullrich, Fred / Gaglioti, Anne H / Dugan, Susan / Chen, May S / Hall, Diane M

The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association

2021 Volume 37, Issue 2, Page(s) 272–277

Abstract: Purpose: This report compares COVID-19 incidence and mortality rates in the nonmetropolitan areas of the United States with the metropolitan areas across three 11-week periods from March 1 to October 18, 2020.: Methods: County-level COVID-19 case, ... ...

Abstract	Purpose: This report compares COVID-19 incidence and mortality rates in the nonmetropolitan areas of the United States with the metropolitan areas across three 11-week periods from March 1 to October 18, 2020. Methods: County-level COVID-19 case, death, and population counts were downloaded from USAFacts.org. The 2013 NCHS Urban-Rural Classification Scheme was collapsed into two categories called metropolitan (large central, large fringe, medium, and small metropolitans) and nonmetropolitan (micropolitan/noncore). Daily COVID-19 incidence and mortality rates were computed to show temporal trends for each of these two categories. Maps showing the ratio of nonmetropolitan to metropolitan COVID-19 incidence and mortality rates by state identify states with higher rates in nonmetropolitan areas than in metropolitan areas in each of the three 11-week periods. Findings: In the period between March 1 and October 18, 2020, 13.8% of the 8,085,214 confirmed COVID-19 cases and 10.7% of the 217,510 deaths occurred among people residing in nonmetropolitan counties. The nonmetropolitan incidence and mortality trends steadily increased and surpassed those in metropolitan areas, beginning in early August. Conclusions: Despite the relatively small size of the US population living in nonmetropolitan areas, these areas have an equal need for testing, health care personnel, and mitigation resources. Having state-specific rural data allow the development of prevention messages that are tailored to the sociocultural context of rural locations.
MeSH term(s)	COVID-19/epidemiology ; Humans ; Incidence ; Pandemics ; Rural Population/statistics & numerical data ; Suburban Population/statistics & numerical data ; United States/epidemiology ; Urban Population/statistics & numerical data
Language	English
Publishing date	2021-02-22
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	639160-6
ISSN	1748-0361 ; 0890-765X
ISSN (online)	1748-0361
ISSN	0890-765X
DOI	10.1111/jrh.12555
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Article ; Online: Climate Change Harm Perception Among U.S. Adults in the NCI Health Information National Trends Survey, 2022.

Muro, Abigail / Czajkowski, Susan / Hall, Kara L / Neta, Gila / Weaver, Sallie J / D'Angelo, Heather

American journal of health promotion : AJHP

2024 , Page(s) 8901171241228339

Abstract: Purpose: To examine associations between 1) sociodemographics and 2) trust in health information sources with climate change harm perception.: Methods: Weighted adjusted logistic regression models examined correlates of climate change harm perception ...

Abstract	Purpose: To examine associations between 1) sociodemographics and 2) trust in health information sources with climate change harm perception. Methods: Weighted adjusted logistic regression models examined correlates of climate change harm perception (harm vs no harm/don't know) among a nationally representative sample of U.S. adults (2022, n = 5585). Results: Sixty-four percent of U.S. adults believed climate change will harm their health. College education (vs high school or less) (AOR 1.7, 95% CI 1.3, 2.2) and having greater trust in doctors (AOR 1.4, 95% CI 1.2, 1.7), scientists (aOR 1.8, 95% CI 1.6, 2.0), and government health agencies (AOR 1.7, 95% CI 1.5, 1.9) for health information were associated with believing climate change harms health. Conversely, greater trust in religious organizations was associated with 16% lower odds of believing climate change harms health (95% CI .74, .94). Conclusions: Climate change harm perception varied by sociodemographics and trust in health information source. Health communication delivered via alternative and diverse channels could expand the reach of climate and health messaging and ultimately increase public awareness and support for measures to mitigate the health impacts of climate change.
Language	English
Publishing date	2024-01-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	645160-3
ISSN	2168-6602 ; 0890-1171
ISSN (online)	2168-6602
ISSN	0890-1171
DOI	10.1177/08901171241228339
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Article ; Online: The Reach Up Parenting Program, Child Development, and Maternal Depression: A Meta-analysis.

Jervis, Pamela / Coore-Hall, Jacqueline / Pitchik, Helen O / Arnold, Charles D / Grantham-McGregor, Sally / Rubio-Codina, Marta / Baker-Henningham, Helen / Fernald, Lia C H / Hamadani, Jena / Smith, Joanne A / Trias, Julieta / Walker, Susan P

Pediatrics

2023 Volume 151, Issue Suppl 2

Abstract: Background and objectives: Evidence is needed on effective approaches to build parents' ability to promote child development feasible in low- and middle-income countries. Our objective was to synthesize impact of the Reach Up early childhood parenting ... ...

Abstract	Background and objectives: Evidence is needed on effective approaches to build parents' ability to promote child development feasible in low- and middle-income countries. Our objective was to synthesize impact of the Reach Up early childhood parenting program in several low- and middle-income countries and examine moderation by family and implementation characteristics. Methods: Systematic search using PubMed and Academic Search Elite/EBSCO Host. Randomized controlled trials of the Reach Up program from 1985 to February 2022 were selected. Data were extracted by 2 independent researchers. Primary outcomes were child cognitive, language, and motor development. Secondary outcomes were home stimulation and maternal depressive symptoms. We synthesized pooled effect sizes using random effect inverse-variance weighting and effect modification by testing pooled subgroup effect estimates using the χ2 test for heterogeneity. Results: Average effect size across 18 studies ranged from 0.49 (95% confidence interval [CI] 0.32 to 0.66) for cognition, 0.38 (CI 0.24 to 0.51) for language, 0.27 (CI 0.13 to 0.40) for motor development, 0.37 (CI 0.21 to 0.54) for home stimulation, and -0.09 (CI -0.19 to 0.01) for maternal depressive symptoms. Impacts were larger in studies targeted to undernourished children, with mean enrollment older than age 12 months and intervention duration 6 to 12 months. Quality of evidence assessed with the Cochrane Assessment of Risk of Bias and GRADE system was moderate. Instruments used to assess child development varied. In moderator analyses, some subgroups included few studies. Conclusions: Reach Up benefits child development and home stimulation and is adaptable across cultures and delivery methods. Child and implementation characteristics modified the effects, with implications for scaling.
MeSH term(s)	Child ; Child, Preschool ; Humans ; Infant ; Parenting ; Child Development ; Depression/diagnosis ; Parents ; Cognition
Language	English
Publishing date	2023-04-26
Publishing country	United States
Document type	Meta-Analysis ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	207677-9
ISSN	1098-4275 ; 0031-4005
ISSN (online)	1098-4275
ISSN	0031-4005
DOI	10.1542/peds.2023-060221D
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Article ; Online: Using lessons learnt from key stakeholders to increase support for scaling the Reach Up Early Childhood Parenting program.

Coore-Hall, Jacqueline / Smith, Joanne / Kelly, Melissa / Baker-Henningham, Helen / Chang, Susan / Walker, Susan

Frontiers in public health

2023 Volume 11, Page(s) 1151826

Abstract: Introduction: Sustainable implementation of early childhood programs requires resources, materials and methods that are adaptable, scalable and feasible for delivery through multiple sectors. Additional or modified program resources may be required to ... ...

Abstract	Introduction: Sustainable implementation of early childhood programs requires resources, materials and methods that are adaptable, scalable and feasible for delivery through multiple sectors. Additional or modified program resources may be required to meet emerging needs, as programs go to scale. An active and effective monitoring, evaluation and learning (MEL) process may enable programs to be responsive to demands. The Reach Up: Early Childhood Parenting program, is designed primarily for disadvantaged children under 4 years of age in low- and middle-income countries (LMICs) to promote their development through playful caregiver interactions. The curriculum, training manuals and other materials and resources support implementers in the adaptation of the intervention, implementation, workforce training, monitoring and evaluation. This paper reports on how data collected from key informants drove modifications to program processes, materials and resources. Methods: We conducted in-depth interviews with 14 key informants (including program managers, lead trainers, academics, consultants and workforce personnel) on their experiences with Reach Up across 15 LMICs where the program has been implemented. We also reviewed written records generated from (i) structured small group discussions at a Knowledge Exchange meeting of 31 Reach Up partners and (ii) notes from working groups formed at the meeting and tasked to continue working post-meeting to find solutions to support ongoing implementation. The transcripts from the in-depth interviews and the meeting records were analysed using thematic analysis with a mixture of pre-defined categories and data-driven sub-themes. Results: The main findings indicated that there was a need to: (i) develop advocacy and communication resources and materials to aid prospective implementers and other stakeholders, to make decisions for implementation, (ii) revise and/or add to the content and format of the curriculum and add content in the training and other supporting manuals and (iii) enhance the training process. Conclusion: The feedback from the key global partners informed the development of new knowledge materials, resources and processes and modifications to existing program materials and resources. These will help to support advocacy, ongoing implementations, and the process of transitioning the Reach Up early childhood intervention to scale.
MeSH term(s)	Child ; Child, Preschool ; Humans ; Parenting ; Prospective Studies ; Learning ; Curriculum ; Early Intervention, Educational
Language	English
Publishing date	2023-08-08
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1151826
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Article ; Online: Caution When Screening for Autism among Socially Anxious Youth.

Capriola-Hall, Nicole N / McFayden, Tyler / Ollendick, Thomas H / White, Susan W

Journal of autism and developmental disorders

2020 Volume 51, Issue 5, Page(s) 1540–1549

Abstract: Social anxiety disorder (SAD) is commonly comorbid with autism spectrum disorder (ASD). Here, in a sample of 86 children and adolescents ( ... ...

Abstract	Social anxiety disorder (SAD) is commonly comorbid with autism spectrum disorder (ASD). Here, in a sample of 86 children and adolescents (M
MeSH term(s)	Adolescent ; Ambulatory Care Facilities/trends ; Autism Spectrum Disorder/diagnosis ; Autism Spectrum Disorder/epidemiology ; Autism Spectrum Disorder/psychology ; Case-Control Studies ; Child ; Diagnosis, Differential ; Female ; Humans ; Male ; Mass Screening/methods ; Mass Screening/standards ; Phobia, Social/diagnosis ; Phobia, Social/epidemiology ; Phobia, Social/psychology
Language	English
Publishing date	2020-08-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	391999-7
ISSN	1573-3432 ; 0162-3257
ISSN (online)	1573-3432
ISSN	0162-3257
DOI	10.1007/s10803-020-04642-w
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Article ; Online: Machine learning-assisted high-content imaging analysis of 3D MCF7 microtissues for estrogenic effect prediction.

Li, Hui / Seada, Haitham / Madnick, Samantha / Zhao, He / Chen, Zhaozeng / Li, Fengcheng / Zhu, Feng / Hall, Susan / Boekelheide, Kim

Scientific reports

2024 Volume 14, Issue 1, Page(s) 2999

Abstract: Endocrine-disrupting chemicals (EDCs) pose a significant threat to human well-being and the ecosystem. However, in managing the many thousands of uncharacterized chemical entities, the high-throughput screening of EDCs using relevant biological endpoints ...

Abstract	Endocrine-disrupting chemicals (EDCs) pose a significant threat to human well-being and the ecosystem. However, in managing the many thousands of uncharacterized chemical entities, the high-throughput screening of EDCs using relevant biological endpoints remains challenging. Three-dimensional (3D) culture technology enables the development of more physiologically relevant systems in more realistic biochemical microenvironments. The high-content and quantitative imaging techniques enable quantifying endpoints associated with cell morphology, cell-cell interaction, and microtissue organization. In the present study, 3D microtissues formed by MCF-7 breast cancer cells were exposed to the model EDCs estradiol (E2) and propyl pyrazole triol (PPT). A 3D imaging and image analysis pipeline was established to extract quantitative image features from estrogen-exposed microtissues. Moreover, a machine-learning classification model was built using estrogenic-associated differential imaging features. Based on 140 common differential image features found between the E2 and PPT group, the classification model predicted E2 and PPT exposure with AUC-ROC at 0.9528 and 0.9513, respectively. Deep learning-assisted analysis software was developed to characterize microtissue gland lumen formation. The fully automated tool can accurately characterize the number of identified lumens and the total luminal volume of each microtissue. Overall, the current study established an integrated approach by combining non-supervised image feature profiling and supervised luminal volume characterization, which reflected the complexity of functional ER signaling and highlighted a promising conceptual framework for estrogenic EDC risk assessment.
MeSH term(s)	Humans ; Estrogens ; MCF-7 Cells ; Ecosystem ; Estradiol ; Estrone ; Machine Learning ; Endocrine Disruptors
Chemical Substances	Estrogens ; Estradiol (4TI98Z838E) ; Estrone (2DI9HA706A) ; Endocrine Disruptors
Language	English
Publishing date	2024-02-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-53323-6
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