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  1. Article ; Conference proceedings: 14th International Symposium on Sjögren's Syndrome

    Baer, Alan N.

    Sjögren's syndrome 2018 Seite S-241-S-338

    April 18-21, 2018, Washington, DC, USA

    2018  

    Event/congress International Symposium on Sjögren's Syndrome (14., 2018, WashingtonDC)
    Author's details directors Alan N. Baer, MD, Esen K. Akpek, MD, Ilias Alevizos, DMD, PhD
    Collection Sjögren's syndrome ...
    Language English
    Size Illustrationen, Diagramme
    Publishing place Pisa, [2018]
    Publishing country Italy
    Document type Article ; Conference proceedings
    HBZ-ID HT019932654
    Database Catalogue ZB MED Medicine, Health

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    Zs A 2002 -Suppl.112-

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  2. Article ; Online: Improving the Diagnostic Approach to Sjögren Syndrome: A 90-Year Quest.

    Baer, Alan N

    Arthritis & rheumatology (Hoboken, N.J.)

    2024  Volume 76, Issue 3, Page(s) 348–350

    MeSH term(s) Humans ; Sjogren's Syndrome/diagnosis
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Editorial
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.42735
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  3. Article ; Online: Potential and challenges with real-world data in medicine.

    Brennan, Michael T / Baer, Alan N

    Oral diseases

    2023  Volume 30, Issue 3, Page(s) 828–829

    MeSH term(s) Humans
    Language English
    Publishing date 2023-04-05
    Publishing country Denmark
    Document type Editorial
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14570
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    Zs.A 4427: Show issues Location:
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  4. Article ; Online: Oasis or mirage-a new drug shows promise for Sjögren's syndrome.

    Baer, Alan N

    The Lancet. Rheumatology

    2020  Volume 2, Issue 3, Page(s) e123–e125

    Language English
    Publishing date 2020-01-23
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(19)30143-2
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  5. Article ; Online: Evaluation and management of dry mouth and its complications in rheumatology practice.

    Khavandgar, Zohreh / Warner, Blake M / Baer, Alan N

    Expert review of clinical immunology

    2024  Volume 20, Issue 1, Page(s) 1–19

    Abstract: Introduction: The symptom of dry mouth has multiple potential etiologies and can be a diagnostic clue to the presence of common systemic diseases encountered in rheumatology practice. The presence of decreased saliva flow (i.e. salivary hypofunction) ... ...

    Abstract Introduction: The symptom of dry mouth has multiple potential etiologies and can be a diagnostic clue to the presence of common systemic diseases encountered in rheumatology practice. The presence of decreased saliva flow (i.e. salivary hypofunction) defines a subset of dry mouth patients in whom there may be reversible drug effects, an iatrogenic insult such as head and neck irradiation, or a disease that directly involves the salivary glands (e.g. Sjögren's disease). The assessment of salivary hypofunction includes sialometry, salivary gland imaging, salivary gland biopsy, and an assessment for relevant systemic diseases. Optimal management of dry mouth requires accurate definition of its cause, followed by general measures that serve to alleviate its symptoms and prevent its complications.
    Areas covered: Through a literature search on xerostomia and salivary hypofunction, we provide an overview of the causes of dry mouth, highlight the potential impact of salivary hypofunction on oral and systemic health, detail routine evaluation methods and treatment strategies, and emphasize the importance of collaboration with oral health care providers.
    Expert opinion: Our Expert Opinion is provided on unmet needs in the management of dry mouth and relevant research progress in the field.
    MeSH term(s) Humans ; Expert Testimony ; Rheumatology ; Salivary Glands ; Sjogren's Syndrome/complications ; Sjogren's Syndrome/diagnosis ; Sjogren's Syndrome/therapy ; Xerostomia/diagnosis ; Xerostomia/etiology ; Xerostomia/therapy
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2023.2268283
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  6. Article ; Online: Reply.

    Baer, Alan N / Hammitt, Katherine M

    Arthritis & rheumatology (Hoboken, N.J.)

    2021  Volume 74, Issue 2, Page(s) 367–368

    Language English
    Publishing date 2021-12-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.41954
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  7. Article ; Online: Sjögren's Disease, Not Syndrome.

    Baer, Alan N / Hammitt, Katherine M

    Arthritis & rheumatology (Hoboken, N.J.)

    2021  Volume 73, Issue 7, Page(s) 1347–1348

    MeSH term(s) Disease ; Humans ; Sjogren's Syndrome ; Syndrome ; Terminology as Topic
    Language English
    Publishing date 2021-06-01
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.41676
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  8. Article: Hyperviscosity Syndrome in Rheumatoid Arthritis.

    Miller, John B / Baer, Alan N

    The Journal of rheumatology

    2021  Volume 48, Issue 5, Page(s) 788–789

    MeSH term(s) Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/drug therapy ; Humans ; Rheumatoid Factor ; Syndrome
    Chemical Substances Rheumatoid Factor (9009-79-4)
    Language English
    Publishing date 2021-01-15
    Publishing country Canada
    Document type Letter
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.200591
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  9. Article ; Online: In Reply.

    Warner, Blake / Baer, Alan

    The oncologist

    2019  Volume 25, Issue 2, Page(s) e396–e397

    MeSH term(s) Humans ; Sjogren's Syndrome
    Language English
    Publishing date 2019-11-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1409038-7
    ISSN 1549-490X ; 1083-7159
    ISSN (online) 1549-490X
    ISSN 1083-7159
    DOI 10.1634/theoncologist.2019-0515
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  10. Article ; Online: Toward better outcomes in Sjögren's syndrome: The promise of a stratified medicine approach.

    Noaiseh, Ghaith / Baer, Alan N

    Best practice & research. Clinical rheumatology

    2020  Volume 34, Issue 1, Page(s) 101475

    Abstract: Sjögren's syndrome is a systemic autoimmune disease defined by its targeted inflammation of the salivary and lacrimal glands, resulting in dry mouth and eyes in the majority and persistent or recurrent salivary gland enlargement in a minority of those ... ...

    Abstract Sjögren's syndrome is a systemic autoimmune disease defined by its targeted inflammation of the salivary and lacrimal glands, resulting in dry mouth and eyes in the majority and persistent or recurrent salivary gland enlargement in a minority of those affected. Involvement of major organs, an increased risk of lymphoma, and autoantibodies against ubiquitous cellular ribonucleoproteins define some of its systemic features. Those affected have a high symptom burden and the development of disease-modifying therapies is thus an urgent need. A stratified medicine approach offers promise as a means of targeting specific therapies to patients for whom the mechanism of action is most relevant. Implementation of this approach will require an understanding of the pathophysiological processes underlying different patient subsets, and then identifying or developing a drug that targets this pathway. Such therapies would be most effective if implemented early in the disease course before the advent of adverse outcomes or glandular damage. This review will provide a disease overview followed by an analysis of the feasibility of a stratified medicine approach, focusing on the disease heterogeneity, predictors of disease progression and adverse outcomes, and recent advances in the development of relevant outcome measures and new therapies.
    MeSH term(s) Autoantibodies ; Humans ; Salivary Glands ; Sjogren's Syndrome/diagnosis ; Sjogren's Syndrome/drug therapy
    Chemical Substances Autoantibodies
    Language English
    Publishing date 2020-01-28
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2052323-3
    ISSN 1532-1770 ; 1521-6942
    ISSN (online) 1532-1770
    ISSN 1521-6942
    DOI 10.1016/j.berh.2019.101475
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