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  1. Article: Cor Adiposum as the Cause of Sudden Cardiac Death: A Case Report and Literature Review.

    Dinning, Emily / Muttana, Srinuvasula / Bardarov, Svetoslav

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55561

    Abstract: We present a case of sudden cardiac death in a 65-year-old patient who came to the emergency room with shortness of breath. The gross examination of the heart was significant for extensive left ventricular lipomatosis in association with myocardial ... ...

    Abstract We present a case of sudden cardiac death in a 65-year-old patient who came to the emergency room with shortness of breath. The gross examination of the heart was significant for extensive left ventricular lipomatosis in association with myocardial fibrosis. Microscopic examination revealed extensive fatty replacement of the myocardial tissue throughout the entire thickness of the ventricular wall (transmural lipomatous myocardial remodeling). We suggest using the term "cor adiposum" to categorize this morphological condition when the transmural lipomatous transformation of the myocardium is present. The fatty replacement of the heart muscle would have led to impaired cardiac function, ultimately resulting in sudden cardiac death in this patient. We also hypothesize that the accumulation of fat in the myocardium might be a compensatory process to preserve ventricular wall compliance.
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55561
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Diffuse Alveolar Hemorrhage Occurring Suddenly in a Diabetic Patient With Asthma Exacerbation.

    Bardarov, Svetoslav / Vue, Chong / Santana, Rochell / Nfonoyim, Jay

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51893

    Abstract: Diffuse alveolar hemorrhage (DAH) is a rare but potentially life-threatening condition characterized by bleeding into the alveolar spaces of the lungs. DAH can occur due to a wide range of etiologies including autoimmune diseases, infections, drugs, and ... ...

    Abstract Diffuse alveolar hemorrhage (DAH) is a rare but potentially life-threatening condition characterized by bleeding into the alveolar spaces of the lungs. DAH can occur due to a wide range of etiologies including autoimmune diseases, infections, drugs, and malignancies. The clinical presentation is variable and may include cough, dyspnea, fever, and hemoptysis. Diagnosis is often challenging due to the nonspecific symptoms and a lack of definitive diagnostic criteria. Treatment is primarily aimed at addressing the underlying cause and providing supportive care.
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Massive Hemorrhage Following Spontaneous Mediastinal Inflammatory Myofibroblastic Tumor Rupture: A Case Report.

    Bellegarde, Sophia B / Gibson, Vanessa / Andaz, Shahriyour / Huang, Lillian / Robinson, Eric / Turi, George / Tofuah, Donald / Ekhator, Chukwuyem / Bardarov, Svetoslav

    Cureus

    2023  Volume 15, Issue 9, Page(s) e45833

    Abstract: A 45-year-old male in a hypertensive emergency was admitted with complaints of frontal headache, progressive chest discomfort, shortness of breath, dysphagia, and right upper quadrant abdominal pain radiating across the epigastrium and to the back that ... ...

    Abstract A 45-year-old male in a hypertensive emergency was admitted with complaints of frontal headache, progressive chest discomfort, shortness of breath, dysphagia, and right upper quadrant abdominal pain radiating across the epigastrium and to the back that increases in intensity with deep inspiration. He denied any history of abdominal pain, vomiting, dyspnea, nausea, and weight loss. A computed tomography (CT) scan of the chest showed a posterior mediastinal mass between the esophagus and descending aorta. A magnetic resonance imaging (MRI) scan revealed a non-enhancing posterior mediastinal mass possibly compressing both the esophagus and the airway. A 30-degree thoracoscope was inserted in the chest cavity revealing a large hemothorax from a possibly ruptured inflammatory myofibroblastic tumor (IMT) encompassing nearly the entire pleural space with both fresh and clotted blood. Two liters of fresh blood was removed via a right thoracotomy procedure. Once removed, a large fibrinous clot-filled mass was resected entirely and sent to pathology. Postoperative recovery was uneventful; dysphagia and shortness of breath resolved. The patient gradually resumed his regular diet.
    Language English
    Publishing date 2023-09-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.45833
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Ectopic Cushing Syndrome in Adenocarcinoma of the Lung: Case Report and Literature Review.

    Al-Zakhari, Rana / Aljammali, Safa / Ataallah, Basma / Bardarov, Svetoslav / Otterbeck, Philip

    Cureus

    2021  Volume 13, Issue 4, Page(s) e14733

    Abstract: Paraneoplastic syndromes are rare disorders that occur with many types of tumors. Ectopic cushing syndrome (ECS) is the second most common paraneoplastic syndrome that is only seen in 1-5% of all small cell lung cancers (SCLC), with limited papers ... ...

    Abstract Paraneoplastic syndromes are rare disorders that occur with many types of tumors. Ectopic cushing syndrome (ECS) is the second most common paraneoplastic syndrome that is only seen in 1-5% of all small cell lung cancers (SCLC), with limited papers reporting this syndrome since it was first described by Brown in 1928 or in carcinoid tumors. It is also found to be associated to a lesser extent with pheochromocytoma, thymic tumors, pancreatic carcinoma, and anaplastic thyroid carcinoma. While lung adenocarcinoma is the most common histological type of lung neoplasms, it is seldom associated with Cushing syndrome. In this article, we describe a patient who initially presented with Cushing syndrome and found to have adenocarcinoma of the lung.
    Language English
    Publishing date 2021-04-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.14733
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Unique presentation of occult breast cancer with uterine cervix metastasis.

    Cimpeanu, Emanuela / Ahmed, Jibran / Tricorico, Gabrielle / Bardarov, Svetoslav / Shulimovich, Maxim / Lakhi, Nisha

    Clinical case reports

    2019  Volume 7, Issue 8, Page(s) 1573–1576

    Abstract: We are reporting a case of occult breast cancer (OBC) diagnosed via biopsy of an asymptomatic cervical mass. While non-OBC has occasionally been reported as metastatic to the uterine cervix, OBC never has, to our knowledge. Awareness of this presentation ...

    Abstract We are reporting a case of occult breast cancer (OBC) diagnosed via biopsy of an asymptomatic cervical mass. While non-OBC has occasionally been reported as metastatic to the uterine cervix, OBC never has, to our knowledge. Awareness of this presentation can be beneficial for a more expedite diagnosis and treatment.
    Language English
    Publishing date 2019-07-10
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.2306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Pembrolizumab - emerging treatment of pulmonary sarcomatoid carcinoma: A case report.

    Cimpeanu, Emanuela / Ahmed, Jibran / Zafar, Wahib / DeMarinis, Adreana / Bardarov, Svetoslav S / Salman, Shamim / Bloomfield, Dennis

    World journal of clinical cases

    2020  Volume 8, Issue 1, Page(s) 97–102

    Abstract: Background: Few studies have addressed the efficacy of pembrolizumab in pulmonary sarcomatoid carcinoma (PSC), a rare, previously rapidly fatal subtype of non-small-cell lung cancer.: Case summary: We report the case of a 69-year-old man presented ... ...

    Abstract Background: Few studies have addressed the efficacy of pembrolizumab in pulmonary sarcomatoid carcinoma (PSC), a rare, previously rapidly fatal subtype of non-small-cell lung cancer.
    Case summary: We report the case of a 69-year-old man presented with respiratory distress caused by a large left upper lung lobe mass diagnosed as PSC with programmed death-ligand 1 expressed on more than 50 percent of tumor cells. The patient was started on pembrolizumab and, after 5 cycles, there was a more than 80 percent decrease in the size of the tumor mass. Further decrease was seen at the end of 10 cycles. The patient has been tolerating pembrolizumab well, with no limiting side-effects. Fourteen months after first coming into the hospital, he remains asymptomatic.
    Conclusion: Pembrolizumab appears as a viable emerging treatment for PSC.
    Language English
    Publishing date 2020-01-23
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v8.i1.97
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Chembio DPP COVID-19 IgM/IgG Serological Testing: Laboratory Validation, Guidelines, and Recommendations.

    Bardarov, S / Cesare, J / Kopolovich, H / Otterbeck, P / LaBarbera, M / Nfonoyim, J / Salhany, R / Rotatori, F / Mantello, G

    Clinical laboratory

    2020  Volume 66, Issue 11

    Abstract: Background: On January 30, 2020, WHO declared COVID-19 a pandemic. In this article we describe our experience at Richmond University Medical Center with Chembio serological IgM, IgG testing.: Methods: In this prospective cohort study of patients and ... ...

    Abstract Background: On January 30, 2020, WHO declared COVID-19 a pandemic. In this article we describe our experience at Richmond University Medical Center with Chembio serological IgM, IgG testing.
    Methods: In this prospective cohort study of patients and hospital employees, we utilized Chembio COVID-19 IgM/IgG serological testing in addition to Cepheid RT-PCR analysis.
    Results: We evaluated the performance of Chembio serological test for IgM and IgG as an employee screening tool in a community hospital setting. The total number of currently asymptomatic employees screened was 1,866 from the Richmond University Medical Center. The non-exposed group included 1,253 (67.1%) employees with no significant clinical history and non-reactive IgM and IgG antibodies. The convalescent group included 255 (13.7%) of the employees with elevation of IgG only, 18 (1%) employees with past history of positive PCR and COVID-19 who currently have non-reactive IgM and IgG antibodies or demonstrate elevated IgG only, followed by 3 employees (< 1%) with no past clinical history who demonstrated reactive IgM and IgG antibodies and negative follow up by PCR. The reported 14.9% exposure/convalescent rate is lower than the reported 20% by the Department of Health and Governor Andrew Cuomo and may represent a better utilization of personal protective equipment, better hand washing techniques, and better disinfection procedures combined with strict social distancing.
    Conclusions: Chembio's performance is satisfactory; however, hospitals must design their own policies addressing: who needs to be screened and who will interpret the results as well as constructing management algorithms for employees with no previous history and current double positive antibodies.
    MeSH term(s) COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/blood ; Coronavirus Infections/diagnosis ; Guidelines as Topic ; Humans ; Immunoglobulin G/analysis ; Immunoglobulin M/analysis ; Mass Screening/methods ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/diagnosis ; Serologic Tests/statistics & numerical data
    Chemical Substances Immunoglobulin G ; Immunoglobulin M
    Keywords covid19
    Language English
    Publishing date 2020-11-24
    Publishing country Germany
    Document type Journal Article ; Validation Study
    ZDB-ID 1307629-2
    ISSN 1433-6510 ; 0941-2131
    ISSN 1433-6510 ; 0941-2131
    DOI 10.7754/Clin.Lab.2020.200850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  8. Article: Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review.

    Kagan, Joseph Alan / Wu, Susan / Bardarov, Svetoslav

    Journal of cytology

    2015  Volume 34, Issue 2, Page(s) 101–103

    Abstract: We present a case of metastatic malignant melanoma to the urinary bladder diagnosed on a voided urinary cytology specimen in a patient who visited the emergency department complaining of right flank pain, and dark urine. The patient reported having ... ...

    Abstract We present a case of metastatic malignant melanoma to the urinary bladder diagnosed on a voided urinary cytology specimen in a patient who visited the emergency department complaining of right flank pain, and dark urine. The patient reported having previous episodes of kidney stones. Additionally, more detailed clinical history obtained after the cytological diagnosis, revealed a previous excision of malignant melanoma on the back 10 years ago. The diagnosis of metastatic malignant melanoma was based solely on voided urine cytology. While metastases of malignant melanoma to urinary bladder are well known, the significance of pigmented cells in voided urine specimens is not well documented. In this article we provide a discussion as well as a review of the literature about possible disease entities associated with pigment containing urothelial as well as non-urothelial cells.
    Language English
    Publishing date 2015-06-12
    Publishing country India
    Document type Case Reports
    ZDB-ID 645018-0
    ISSN 0970-9371
    ISSN 0970-9371
    DOI 10.4103/0970-9371.203578
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3274: Show issues Location:
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  9. Article ; Online: Tufted hair folliculitis: a case report and literature review.

    Broshtilova, V / Bardarov, E / Kazandjieva, J / Marina, S

    Acta dermatovenerologica Alpina, Pannonica, et Adriatica

    2011  Volume 20, Issue 1, Page(s) 27–29

    Abstract: Tufted hair folliculitis is a rare folliculitis of the scalp that resolves with patches of scarring alopecia within multiple hair tufts emerging from dilated follicular orifices. Tufting of hair is caused by clustering of adjacent follicular units due to ...

    Abstract Tufted hair folliculitis is a rare folliculitis of the scalp that resolves with patches of scarring alopecia within multiple hair tufts emerging from dilated follicular orifices. Tufting of hair is caused by clustering of adjacent follicular units due to a fibrosing process and to retention of telogen hairs within a dilated follicular orifice. Various pathogenetic mechanisms have been proposed including nevoid abnormalities, recurrent infections of the follicles, and retention of telogen hair in the tufts. We present a patient with tufted hair folliculitis who was effectively treated with antibacterial medications, verifying the infectious nature of the disease.
    MeSH term(s) Adult ; Diagnosis, Differential ; Folliculitis/complications ; Folliculitis/diagnosis ; Folliculitis/pathology ; Hair Follicle/pathology ; Humans ; Male ; Scalp Dermatoses/diagnosis ; Scalp Dermatoses/microbiology ; Scalp Dermatoses/pathology ; Staphylococcal Skin Infections/complications
    Language English
    Publishing date 2011
    Publishing country Slovenia
    Document type Case Reports ; Journal Article
    ZDB-ID 2163601-1
    ISSN 1581-2979 ; 1318-4458
    ISSN (online) 1581-2979
    ISSN 1318-4458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Adult rhabdomyosarcoma of the maxillary sinus with orbital extension.

    Parikh, Deep / Spindle, Jordan / Linden, Craig / Bardarov, Svetoslav / Shinder, Roman

    Orbit (Amsterdam, Netherlands)

    2014  Volume 33, Issue 4, Page(s) 302–304

    Abstract: A 40-year-old male presented with 2 weeks of left facial pain, nasal congestion, dysphonia, and epistaxis along with left-sided epiphora. CT showed a large infiltrative mass centered in the left maxillary sinus with extension into the left orbit, ... ...

    Abstract A 40-year-old male presented with 2 weeks of left facial pain, nasal congestion, dysphonia, and epistaxis along with left-sided epiphora. CT showed a large infiltrative mass centered in the left maxillary sinus with extension into the left orbit, bilateral paranasal sinuses, nasal cavity, and bilateral enlarged cervical lymph nodes. Biopsy results confirmed adult alveolar rhabdomyosarcoma (RMS). Systemic workup confirmed bilateral cervical lymph node metastasis. Currently the patient is undergoing chemotherapy. We describe a rare case of adult paranasal sinus RMS with orbital invasion.
    MeSH term(s) Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Humans ; Lymphatic Metastasis ; Male ; Maxillary Sinus Neoplasms/diagnostic imaging ; Maxillary Sinus Neoplasms/drug therapy ; Maxillary Sinus Neoplasms/pathology ; Orbital Neoplasms/diagnostic imaging ; Orbital Neoplasms/drug therapy ; Orbital Neoplasms/secondary ; Paranasal Sinus Neoplasms/diagnostic imaging ; Paranasal Sinus Neoplasms/drug therapy ; Paranasal Sinus Neoplasms/secondary ; Rhabdomyosarcoma, Alveolar/diagnostic imaging ; Rhabdomyosarcoma, Alveolar/drug therapy ; Rhabdomyosarcoma, Alveolar/secondary ; Tomography, X-Ray Computed
    Language English
    Publishing date 2014-08
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603157-2
    ISSN 1744-5108 ; 0167-6830
    ISSN (online) 1744-5108
    ISSN 0167-6830
    DOI 10.3109/01676830.2014.902480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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