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  1. Article ; Online: Spread Through Air Spaces in Stage I to III Resected Lung Adenocarcinomas: Should the Presence of Spread Through Air Spaces Lead to an Upstaging?

    Laville, David / Désage, Anne-Laure / Fournel, Pierre / Bayle-Bleuez, Sophie / Neifer, Chaouki / Picot, Tiphanie / Sulaiman, Abdulrazzak / Tiffet, Olivier / Forest, Fabien

    The American journal of surgical pathology

    2024  Volume 48, Issue 5, Page(s) 596–604

    Abstract: ... of STAS was associated with lower PFS, equivalent to the next pathologic T stage, especially the median ...

    Abstract In recent years, the concept of spread through air spaces (STAS) has been discussed as an adverse prognostic factor for lung cancer. The aim of our study is to clarify the prognostic role of STAS in relation to the main recognized prognostic factors in a retrospective cohort of 330 European patients who underwent stages I to III lung adenocarcinoma resection. On univariate analysis, the presence of STAS was related to progression-free survival (PFS; hazard ratio [HR]: 1.48; 95% CI: 1.02-2.19; P = 0.038) and overall survival (OS; HR: 1.61; 95% CI: 1.03-2.52; P = 0.50). On multivariate analysis, STAS was related to PFS (HR: 1.51; 95% CI: 1.00-2.17; P = 0.050) and to OS (HR: 1.67; 95% CI: 1.00-2.81; P = 0.050). We showed that the presence of STAS was associated with lower PFS, equivalent to the next pathologic T stage, especially the median PFS of T3 stages without STAS was at 62.8 months while the median PFS of T3 stages with STAS was at 15.7 months, closer to the median PFS of 17.4 months in T4 stages. To conclude, STAS is an independent prognostic factor of PFS in this European cohort and is close to significance for OS. We suggest that the presence of STAS might lead to an upstaging of lung adenocarcinoma.
    MeSH term(s) Humans ; Retrospective Studies ; Neoplasm Invasiveness/pathology ; Adenocarcinoma of Lung/surgery ; Adenocarcinoma of Lung/pathology ; Lung Neoplasms/pathology ; Adenocarcinoma/surgery ; Adenocarcinoma/pathology ; Prognosis ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752964-8
    ISSN 1532-0979 ; 0147-5185
    ISSN (online) 1532-0979
    ISSN 0147-5185
    DOI 10.1097/PAS.0000000000002188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1356: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Multi-Omics Profiling of

    Alhameed, Rouba Abdulsalam / Semreen, Mohammad H / Hamad, Mohamad / Giddey, Alexander D / Sulaiman, Ashna / Al Bataineh, Mohammad T / Al-Hroub, Hamza M / Bustanji, Yasser / Alzoubi, Karem H / Soares, Nelson C

    Microorganisms

    2023  Volume 11, Issue 12

    Abstract: ... Candida ... ...

    Abstract Candida albicans
    Language English
    Publishing date 2023-11-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11122831
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Metabolite profiling of

    Sulaiman, C T / Ramesh, P R / Mahesh, K / Anandan, E M / Praveen, M / Balachandran, I

    Natural product research

    2021  Volume 36, Issue 14, Page(s) 3726–3730

    Abstract: Cyanthillium ... ...

    Abstract Cyanthillium cinereum
    MeSH term(s) Anti-Inflammatory Agents/pharmacology ; Asteraceae ; Chromatography, High Pressure Liquid/methods ; Flavonoids/chemistry ; Phenols/analysis ; Phytochemicals/analysis ; Plant Extracts/chemistry ; Tandem Mass Spectrometry/methods
    Chemical Substances Anti-Inflammatory Agents ; Flavonoids ; Phenols ; Phytochemicals ; Plant Extracts
    Language English
    Publishing date 2021-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2020.1869972
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: LC/MS characterization of phenolic antioxidants of Brindle berry (Garcinia gummi-gutta (L.) Robson).

    Sulaiman, C T / Balachandran, Indira

    Natural product research

    2017  Volume 31, Issue 10, Page(s) 1191–1194

    Abstract: ... glycoside, dicaffeoylquinic acid, apigenein-6-C-pentosyl-8-C-hexoside and p-coumarylquinic acid were ...

    Abstract Characterisation of antioxidant fraction of the fruit of Garcinia gummi-gutta was done using liquid chromatography mass spectroscopic (LC/MS) analyses. Total poly phenolics and radical scavenging activity of various extracts such as acetone, methanol and hydroalcohol were estimated spectrophotometrically. The active extract was analysed by LC/MS in order to identify the molecular mass and tentative structures of major compounds. Phenolic compounds such as luteolin 7-O-glucuronide, kaempferol 3-O-(6-O-acetyl) glycoside, dicaffeoylquinic acid, apigenein-6-C-pentosyl-8-C-hexoside and p-coumarylquinic acid were identified from hydro alcoholic extract of G. gummi-gutta.
    MeSH term(s) Antioxidants/pharmacology ; Chromatography, Liquid ; Garcinia/chemistry ; Luteolin/pharmacology ; Phenols/analysis ; Phenols/pharmacology ; Plant Extracts/pharmacology ; Tandem Mass Spectrometry
    Chemical Substances Antioxidants ; Phenols ; Plant Extracts ; luteolin-7-O-glucuronide ; Luteolin (KUX1ZNC9J2)
    Language English
    Publishing date 2017-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2016.1224871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Metabolite profiling of Cyanthillium cinereum (L.) H. Rob. and its herbal formulation by tandem mass spectroscopic analysis

    Sulaiman, C. T. / Ramesh, P. R. / Mahesh, K. / Anandan, E. M. / Praveen, M. / Balachandran, I.

    Natural product research. 2022 July 15, v. 36, no. 14

    2022  

    Abstract: ... extract of C. cinereum (CCE) and its herbal formulation KGS tablet has been carried out ...

    Abstract Cyanthillium cinereum is a medicinal plant commonly known as little ironweed is used in various traditional systems of medicines. In Ayurveda, it is known as Sahadevi and is used as remedy for many ailments. It has been reported to possess numerous biological properties including diaphoretic, anthelmintic, diuretic, lithontriptic, anti-inflammatory and anticancer activities. Metabolite profiling of aqueous extract of C. cinereum (CCE) and its herbal formulation KGS tablet has been carried out by liquid chromatography tandem mass spectroscopic analysis. ESI-MS/MS based characterisation led to the identification of several bioactive phytochemicals belonging to various classes of metabolites like phenolic acids, phenolic glycosides, flavonoids and anthocyanin. Most of the identified compounds are known for their various biological properties, such as antioxidant, anti-inflammatory and anticancer activities.
    Keywords Ayurvedic medicine ; Cyanthillium cinereum ; anthelmintics ; anthocyanins ; antioxidants ; liquid chromatography ; medicinal plants ; metabolites ; research ; spectral analysis
    Language English
    Dates of publication 2022-0715
    Size p. 3726-3730.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2020.1869972
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  6. Article: DHCR7 Expression Predicts Poor Outcomes and Mortality from Sepsis.

    Guirgis, Faheem W / Jacob, Vinitha / Wu, Dongyuan / Henson, Morgan / Daly-Crews, Kimberly / Hopson, Charlotte / Black, Lauren Page / DeVos, Elizabeth L / Sulaiman, Dawoud / Labilloy, Guillaume / Brusko, Todd M / Shavit, Jordan A / Bertrand, Andrew / Feldhammer, Matthew / Baskovich, Brett / Graim, Kiley / Datta, Susmita / Reddy, Srinivasa T

    Research square

    2023  

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2023-01-30
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-2500497/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Caralluma pauciflora

    Navaneethan, Renuga Devi / N C J, Packia Lekshmi / Ramaiah, Mariselvam / Ravindran, Rajeswari / T, Ananth Kumar / Chinnathambi, Arunachalam / Ali Alharbi, Sulaiman / Sivagnanam, Ananthi / Mohemedibrahim, Ponnani Kaja Mideen

    Nanotechnology

    2024  Volume 35, Issue 19

    Abstract: The phytochemicals found ... ...

    Abstract The phytochemicals found in
    MeSH term(s) Humans ; Reactive Oxygen Species/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Apocynaceae/metabolism ; Metal Nanoparticles/chemistry ; Stomach Neoplasms/drug therapy ; Down-Regulation ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Silver/pharmacology ; Silver/metabolism ; Apoptosis ; TOR Serine-Threonine Kinases/metabolism ; TOR Serine-Threonine Kinases/pharmacology ; Anti-Bacterial Agents/pharmacology ; Spectroscopy, Fourier Transform Infrared
    Chemical Substances Reactive Oxygen Species ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Plant Extracts ; Silver (3M4G523W1G) ; TOR Serine-Threonine Kinases (EC 2.7.11.1) ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ad26d9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: LC/MS characterization of phenolic antioxidants of Brindle berry (Garcinia gummi-gutta (L.) Robson)

    Sulaiman, C. T / Indira Balachandran

    Natural product research. 2017 May 19, v. 31, no. 10

    2017  

    Abstract: ... glycoside, dicaffeoylquinic acid, apigenein-6-C-pentosyl-8-C-hexoside and p-coumarylquinic acid were ...

    Abstract Characterisation of antioxidant fraction of the fruit of Garcinia gummi - gutta was done using liquid chromatography mass spectroscopic (LC/MS) analyses. Total poly phenolics and radical scavenging activity of various extracts such as acetone, methanol and hydroalcohol were estimated spectrophotometrically. The active extract was analysed by LC/MS in order to identify the molecular mass and tentative structures of major compounds. Phenolic compounds such as luteolin 7-O-glucuronide, kaempferol 3-O-(6-O-acetyl) glycoside, dicaffeoylquinic acid, apigenein-6-C-pentosyl-8-C-hexoside and p-coumarylquinic acid were identified from hydro alcoholic extract of G. gummi - gutta .
    Keywords acetone ; free radical scavengers ; Garcinia ; glycosides ; kaempferol ; liquid chromatography ; luteolin ; methanol ; molecular weight ; phenolic compounds ; spectroscopy
    Language English
    Dates of publication 2017-0519
    Size p. 1191-1194.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2016.1224871
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: An Improved Direct Injection Technique With Flowable Composites. A Digital Workflow Case Report.

    Coachman, C / De Arbeloa, L / Mahn, G / Sulaiman, T A / Mahn, E

    Operative dentistry

    2020  Volume 45, Issue 3, Page(s) 235–242

    Abstract: This article presents a clinical technique based on a case report for restoring the contours and shape of the upper teeth involved in the smile display of a young patient. After planning the treatment for the patient using digital tools (Digital pictures, ...

    Abstract This article presents a clinical technique based on a case report for restoring the contours and shape of the upper teeth involved in the smile display of a young patient. After planning the treatment for the patient using digital tools (Digital pictures, Digital Smile Design, digital waxup, three-dimensional [3D] printed models, mockup), the upper teeth were restored using an improved injection technique. This improved technique involves the direct injection of flowable composite resin using clear polyvinyl siloxane molds made from 3D-printed models of the patient. The details and benefits of this new technique are described in the article.
    MeSH term(s) Composite Resins ; Humans ; Smiling ; Workflow
    Chemical Substances Composite Resins ; flowable hybrid composite
    Language English
    Publishing date 2020-02-26
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 752995-8
    ISSN 1559-2863 ; 0361-7734
    ISSN (online) 1559-2863
    ISSN 0361-7734
    DOI 10.2341/18-151-T
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1963: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Informed Consent: The Surgical Patient's Experience in a Tertiary Hospital in Northwest Nigeria.

    Grema, B A / Tanimu, S T / Michael, G C / Aliyu, I / Aji, S A / Takai, I U / Sulaiman, A I

    West African journal of medicine

    2022  , Issue 5, Page(s) 471–478

    Abstract: Background: Obtaining informed consent (IC) before a surgical procedure is the cornerstone of medical practice. The practice of IC continues to evolve as litigations increase. Most studies on patients' perspectives of IC are either old or were done in ... ...

    Abstract Background: Obtaining informed consent (IC) before a surgical procedure is the cornerstone of medical practice. The practice of IC continues to evolve as litigations increase. Most studies on patients' perspectives of IC are either old or were done in southern Nigeria. This study assessed the surgical patients' IC experience in a tertiary hospital in northwest Nigeria.
    Methods: This cross-sectional study assessed 244 consecutive patients who had elective surgeries in surgical departments of a tertiary hospital. Pretested questionnaires were used to collect data regarding their perception of the meaning of IC, the process of obtaining it, satisfaction with how it was obtained, and factors associated with satisfaction on how consent was obtained.
    Results: Most were females (61.9%); their mean age was 34.8±14.3 years; 52.9% and 61.9% of respondents did not believe that IC enables patient-clinician shared decision-making or patient's self-decision making, respectively. Most were allowed to ask questions (83.2%), received information on the surgical procedure (91.4%), diagnosis (97.9%); however, 38.5% and 48.8% did not receive information about surgical procedures' immediate and long-term complications, respectively. Surgical procedure explanation was mostly provided by Resident Doctors (53.7%). Most (88.9%) were satisfied with how IC was obtained; satisfaction was associated with being allowed to ask questions, receiving explanations on diagnosis, surgical-procedure, complications of surgery, available alternative treatments, and when the resident/ consultants gave the explanation (all P<0.05).
    Conclusion: Deficiencies exist in the process of getting IC. Satisfaction with this process was high though associated with following the recommended strategies. Improving the IC process will require appropriate interventions in this and similar settings.
    MeSH term(s) Adult ; Cross-Sectional Studies ; Female ; Humans ; Informed Consent ; Male ; Middle Aged ; Nigeria ; Surveys and Questionnaires ; Tertiary Care Centers ; Young Adult
    Language English
    Publishing date 2022-05-22
    Publishing country Nigeria
    Document type Journal Article
    ZDB-ID 1132088-6
    ISSN 0189-160X
    ISSN 0189-160X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3527: Show issues Location:
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