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  1. Article ; Online: Convergence Analysis of Mean Shift.

    Yamasaki, Ryoya / Tanaka, Toshiyuki

    IEEE transactions on pattern analysis and machine intelligence

    2024  Volume PP

    Abstract: The mean shift (MS) algorithm seeks a mode of the kernel density estimate (KDE). This study presents a convergence guarantee of the mode estimate sequence generated by the MS algorithm and an evaluation of the convergence rate, under fairly mild ... ...

    Abstract The mean shift (MS) algorithm seeks a mode of the kernel density estimate (KDE). This study presents a convergence guarantee of the mode estimate sequence generated by the MS algorithm and an evaluation of the convergence rate, under fairly mild conditions, with the help of the argument concerning the Łojasiewicz inequality. Our findings extend existing ones covering analytic kernels and the Epanechnikov kernel. Those are significant in that they cover the biweight kernel, which is optimal among non-negative kernels in terms of the asymptotic statistical efficiency for the KDE-based mode estimation.
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Journal Article
    ISSN 1939-3539
    ISSN (online) 1939-3539
    DOI 10.1109/TPAMI.2024.3385920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Genome sequence of

    Tanaka, Reiji / Miyake, Hideo / Shibata, Toshiyuki

    Microbiology resource announcements

    2024  Volume 13, Issue 2, Page(s) e0097223

    Abstract: Genome sequence of an ulvan-degrading bacterium, ...

    Abstract Genome sequence of an ulvan-degrading bacterium,
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.00972-23
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  3. Article ; Online: Multi-stage coherent beam combination of semiconductor optical amplifiers in ready-made fiber couplers.

    Nagano, Akira / Ihara, Toshiyuki / Tanaka, Utako / Hayasaka, Kazuhiro

    Optics express

    2024  Volume 32, Issue 5, Page(s) 6903–6916

    Abstract: We report on multi-stage coherent beam combination (CBC) of continuous-wave (CW) outputs from semiconductor optical amplifiers (SOAs) in ready-made fiber couplers. The first CBC stage combines two 120-mW outputs from SOAs seeded by an extended-cavity ... ...

    Abstract We report on multi-stage coherent beam combination (CBC) of continuous-wave (CW) outputs from semiconductor optical amplifiers (SOAs) in ready-made fiber couplers. The first CBC stage combines two 120-mW outputs from SOAs seeded by an extended-cavity diode laser (ECDL) at 1458 nm in a 2×2 50%:50% fiber coupler. Two beams generated by two such CBC setups are then combined in the second stage. By concatenating three stages we obtained an output power of 723 mW at 1458 nm from eight SOAs with a total combining efficiency of 75.3%. Stable power generation without interrupts nor degradation over three days was successfully implemented using a simple low-bandwidth servo system. An averaged single-stage combining efficiency of 89.5% deduced from seven CBC setups constituting the three-stage CBC is used to estimate scaling to further stages. As a practical application the output is used to second harmonic generation (SHG) in a nonlinear crystal to achieve an output power of 239 mW at 729 nm.
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.511127
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  4. Article ; Online: Author's reply.

    Iwama, Makoto / Noda, Toshiyuki / Takagi, Kensuke / Tanaka, Akihito / Murohara, Toyoaki

    Journal of cardiology

    2023  Volume 82, Issue 5, Page(s) 429–430

    Language English
    Publishing date 2023-09-04
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 639364-0
    ISSN 1876-4738 ; 0386-2887 ; 0914-5087
    ISSN (online) 1876-4738
    ISSN 0386-2887 ; 0914-5087
    DOI 10.1016/j.jjcc.2023.08.015
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Book ; Online: Optimal Kernel for Kernel-Based Modal Statistical Methods

    Yamasaki, Ryoya / Tanaka, Toshiyuki

    2023  

    Abstract: Kernel-based modal statistical methods include mode estimation, regression, and clustering. Estimation accuracy of these methods depends on the kernel used as well as the bandwidth. We study effect of the selection of the kernel function to the ... ...

    Abstract Kernel-based modal statistical methods include mode estimation, regression, and clustering. Estimation accuracy of these methods depends on the kernel used as well as the bandwidth. We study effect of the selection of the kernel function to the estimation accuracy of these methods. In particular, we theoretically show a (multivariate) optimal kernel that minimizes its analytically-obtained asymptotic error criterion when using an optimal bandwidth, among a certain kernel class defined via the number of its sign changes.

    Comment: 51 pages, 4 figures
    Keywords Statistics - Machine Learning ; Computer Science - Machine Learning
    Publishing date 2023-04-19
    Publishing country us
    Document type Book ; Online
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  6. Article ; Online: Pharmacokinetic evaluation of oxaliplatin combined with S-1 (SOX) chemotherapy in a rat model of colorectal cancer with acute kidney injury: predictive renal biomarkers for dose optimisation.

    Tanaka, Takumi / Kobuchi, Shinji / Ito, Yukako / Sakaeda, Toshiyuki

    Xenobiotica; the fate of foreign compounds in biological systems

    2023  Volume 53, Issue 10-11, Page(s) 613–620

    Abstract: Dose adjustment based on renal function is essential in S-1, which contains the 5‑fluorouracil prodrug tegafur, and platinum-based agent oxaliplatin (SOX) combination chemotherapy for colorectal cancer in patients with chronic kidney disease. However, ... ...

    Abstract Dose adjustment based on renal function is essential in S-1, which contains the 5‑fluorouracil prodrug tegafur, and platinum-based agent oxaliplatin (SOX) combination chemotherapy for colorectal cancer in patients with chronic kidney disease. However, limited evidence on dose adjustment in acute kidney injury (AKI) and challenges in determining dosing strategies. This study investigated the pharmacokinetics of SOX chemotherapy and renal biomarkers in rats.AKI was prepared by renal ischaemia-reperfusion injury in 1,2-dimethylhydrazine-induced colorectal cancer model rats. Serum creatinine (
    MeSH term(s) Humans ; Rats ; Animals ; Oxaliplatin ; Tegafur/toxicity ; Tegafur/pharmacokinetics ; Fluorouracil/therapeutic use ; Fluorouracil/pharmacokinetics ; Kidney/pathology ; Acute Kidney Injury/chemically induced ; Acute Kidney Injury/drug therapy ; Biomarkers ; Colorectal Neoplasms/drug therapy ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
    Chemical Substances Oxaliplatin (04ZR38536J) ; Tegafur (1548R74NSZ) ; Fluorouracil (U3P01618RT) ; Biomarkers
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 120287-x
    ISSN 1366-5928 ; 0049-8254
    ISSN (online) 1366-5928
    ISSN 0049-8254
    DOI 10.1080/00498254.2023.2283736
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 782: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Article ; Online: Power of neutrality tests for detecting natural selection.

    Tanaka, Tomotaka / Hayakawa, Toshiyuki / Teshima, Kosuke M

    G3 (Bethesda, Md.)

    2023  Volume 13, Issue 10

    Abstract: Detection of natural selection is one of the main interests in population genetics. Thus, many tests have been developed for detecting natural selection using genomic data. Although it is recognized that the utility of tests depends on several ... ...

    Abstract Detection of natural selection is one of the main interests in population genetics. Thus, many tests have been developed for detecting natural selection using genomic data. Although it is recognized that the utility of tests depends on several evolutionary factors, such as the timing of selection, strength of selection, frequency of selected alleles, demographic events, and initial frequency of selected allele when selection started acting (softness of selection), the relationships between such evolutionary factors and the power of tests are not yet entirely clear. In this study, we investigated the power of 4 tests: Tajiama's D, Fay and Wu's H, relative extended haplotype homozygosity (rEHH), and integrated haplotype score (iHS), under ranges of evolutionary parameters and demographic models to quantitatively expand the understanding of approaches for detecting selection. The results show that each test detects selection within a limited parameter range, and there are still wide ranges of parameters for which none of these tests work effectively. In addition, the parameter space in which each test shows the highest power overlaps the empirical results of previous research. These results indicate that our present perspective of adaptation is limited to only a part of actual adaptation.
    MeSH term(s) Genetics, Population ; Selection, Genetic ; Biological Evolution ; Haplotypes ; Genomics
    Language English
    Publishing date 2023-07-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2629978-1
    ISSN 2160-1836 ; 2160-1836
    ISSN (online) 2160-1836
    ISSN 2160-1836
    DOI 10.1093/g3journal/jkad161
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  8. Book ; Online: Convergence Analysis of Mean Shift

    Yamasaki, Ryoya / Tanaka, Toshiyuki

    2023  

    Abstract: The mean shift (MS) algorithm seeks a mode of the kernel density estimate (KDE). This study presents a convergence guarantee of the mode estimate sequence generated by the MS algorithm and an evaluation of the convergence rate, under fairly mild ... ...

    Abstract The mean shift (MS) algorithm seeks a mode of the kernel density estimate (KDE). This study presents a convergence guarantee of the mode estimate sequence generated by the MS algorithm and an evaluation of the convergence rate, under fairly mild conditions, with the help of the argument concerning the {\L}ojasiewicz inequality. Our findings extend existing ones covering analytic kernels and the Epanechnikov kernel. Those are significant in that they cover the biweight kernel, which is optimal among non-negative kernels in terms of the asymptotic statistical efficiency for the KDE-based mode estimation.

    Comment: 18 pages, 2 figures, preprint version
    Keywords Statistics - Machine Learning ; Computer Science - Machine Learning
    Publishing date 2023-05-15
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: L-arginine supplement-induced esophagitis in an adolescent boy.

    Tanaka, Toshiyuki / Aoki, Yoshihiro / Mizushiro, Naoto

    Pediatrics international : official journal of the Japan Pediatric Society

    2022  Volume 64, Issue 1, Page(s) e15379

    MeSH term(s) Male ; Humans ; Adolescent ; Esophagitis/chemically induced ; Esophagitis/diagnosis ; Arginine/adverse effects
    Chemical Substances Arginine (94ZLA3W45F)
    Language English
    Publishing date 2022-10-06
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1470376-2
    ISSN 1442-200X ; 1328-8067
    ISSN (online) 1442-200X
    ISSN 1328-8067
    DOI 10.1111/ped.15379
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 848: Show issues Location:
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  10. Article ; Online: Vortex structure and fluid force changed by altering whole-body kinematic parameters during underwater undulatory swimming.

    Tanaka, Takahiro / Hashizume, Satoru / Kurihara, Toshiyuki / Isaka, Tadao

    Sports biomechanics

    2023  , Page(s) 1–14

    Abstract: Swimmers generate vortices around their bodies during underwater undulatory swimming (UUS). Alteration of UUS movement would induce changes in vortex structure and fluid force. This study investigated whether a skilled swimmer's movement generated an ... ...

    Abstract Swimmers generate vortices around their bodies during underwater undulatory swimming (UUS). Alteration of UUS movement would induce changes in vortex structure and fluid force. This study investigated whether a skilled swimmer's movement generated an effective vortex and fluid force for increasing the UUS velocity. A three-dimensional digital model and kinematic data yielded during UUS with maximum effort were collected for one skilled and one unskilled swimmer. The skilled swimmer's UUS kinematics were input into the skilled swimmer's model (SK-SM) and unskilled swimmer's model (SK-USM), followed by the kinematics of the unskilled swimmer (USK-USM and USK-SM, respectively). The vortex area, circulation, and peak drag force were determined using computational fluid dynamics. A larger vortex with greater circulation at the ventral side of the trunk and a greater circulation vortex behind the swimmer were observed in SK-USM compared to USK-USM. USK-SM generated a smaller vortex on the ventral side of the trunk and behind the swimmer, with a weaker circulation behind the swimmer compared to SK-SM. The peak drag force was larger for SK-USM than for USK-USM. Our results indicate that an effective vortex for propulsion was generated when a skilled swimmer's UUS kinematics was input in the other swimmer's model.
    Language English
    Publishing date 2023-07-10
    Publishing country England
    Document type Journal Article
    ISSN 1752-6116
    ISSN (online) 1752-6116
    DOI 10.1080/14763141.2023.2233466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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