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Article: A late presentation of a left paraduodenal hernia in an elderly patient admitted in emergency: A case report.

Brogna, Barbara / Urciuoli, Luigi / Musto, Lanfranco Aquilino / Iovine, Lorenzo

2024 Volume 19, Issue 4, Page(s) 1356–1360

Abstract: Small bowel internal hernias (IHs), a rare cause of small bowel occlusion (SBO) and small bowel strangulation, while more commonly seen in young adults, can also affect elderly patients and pose a significant diagnostic challenge due to their nonspecific ...

Abstract	Small bowel internal hernias (IHs), a rare cause of small bowel occlusion (SBO) and small bowel strangulation, while more commonly seen in young adults, can also affect elderly patients and pose a significant diagnostic challenge due to their nonspecific symptoms. In most cases, laparotomy was used to diagnose IHs. However, multidetector computed tomography (MDCT) is usually the best imaging tool to use in the emergency setting for the diagnosis of IHs. An 83-year-old man was admitted to emergency with acute abdominal pain and a coffee-ground vomitus. The abdominal MDCT showed a clustered-like appearance of proximal jejunal loops at the level of the Treitz ligament with the absence of transit of the medium water-soluble iodine oral contrast agent (Gastrografin). Mesenteric edema was also present with initial suffering of the intestinal wall. A left paraduodenal hernia (LPDH) with strangulation was suspected following the radiological report. The emergency laparotomy revealed about 20 cm of proximal jejunal loops herniated through a 3 cm wide hernia orifice (HO) along the Treitz ligament, at the level of Landzert fossa, located in the confluence of the descending mesocolon, posterior to the inferior mesenteric vein (IMV) and confirming the LPDH. The patient was discharged in good condition some days later. IHs do not have sufficient coverage in literature, especially in cases regarding elderly patients, however, they can be a cause of SBO in people older than 80 years of age. Radiologists and surgeons should be aware of the anatomical aspects of the IHs.
Language	English
Publishing date	2024-01-15
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2406300-9
ISSN	1930-0433
ISSN	1930-0433
DOI	10.1016/j.radcr.2024.01.013
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Chest CT Findings after 4 Months from the Onset of COVID-19 Pneumonia: A Case Series.

Urciuoli, Luigi / Guerriero, Elvira

Diagnostics (Basel, Switzerland)

2020 Volume 10, Issue 11

Abstract: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the reference standard for SARS-CoV-2 diagnosis is real-time reverse transcription polymerase chain reaction ...

Abstract	Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the reference standard for SARS-CoV-2 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR), computed tomography (CT) is recommended for both initial evaluation and follow-up. There is a growing body of published evidence about CT evolution during the course of COVID-19 pneumonia. Here, we report six confirmed cases of COVID-19 patients who underwent unenhanced chest CT on admission and after 4 months from the onset of symptoms. Chest-CT at first admission showed the typical CT features of COVID-19. Interestingly, the follow-up CT revealed the persistence of lung abnormalities in five cases even if all the patients were completely asymptomatic. Further studies are needed for a comprehensive understanding of the disease progression and the resulting late imaging modifications.
Keywords	covid19
Language	English
Publishing date	2020-11-03
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics10110899
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Article ; Online: A late presentation of a left paraduodenal hernia in an elderly patient admitted in emergency

Barbara Brogna, MD / Luigi Urciuoli, MD / Lanfranco Aquilino Musto, MD / Lorenzo Iovine, MD

Radiology Case Reports, Vol 19, Iss 4, Pp 1356-

A case report

2024 Volume 1360

Abstract	Small bowel internal hernias (IHs), a rare cause of small bowel occlusion (SBO) and small bowel strangulation, while more commonly seen in young adults, can also affect elderly patients and pose a significant diagnostic challenge due to their nonspecific symptoms. In most cases, laparotomy was used to diagnose IHs. However, multidetector computed tomography (MDCT) is usually the best imaging tool to use in the emergency setting for the diagnosis of IHs. An 83-year-old man was admitted to emergency with acute abdominal pain and a coffee-ground vomitus. The abdominal MDCT showed a clustered-like appearance of proximal jejunal loops at the level of the Treitz ligament with the absence of transit of the medium water-soluble iodine oral contrast agent (Gastrografin). Mesenteric edema was also present with initial suffering of the intestinal wall. A left paraduodenal hernia (LPDH) with strangulation was suspected following the radiological report. The emergency laparotomy revealed about 20 cm of proximal jejunal loops herniated through a 3 cm wide hernia orifice (HO) along the Treitz ligament, at the level of Landzert fossa, located in the confluence of the descending mesocolon, posterior to the inferior mesenteric vein (IMV) and confirming the LPDH. The patient was discharged in good condition some days later. IHs do not have sufficient coverage in literature, especially in cases regarding elderly patients, however, they can be a cause of SBO in people older than 80 years of age. Radiologists and surgeons should be aware of the anatomical aspects of the IHs.
Keywords	Internal hernia ; Small bowel obstruction ; Emergency ; Multidetector computed tomography ; Left paraduodenal hernia ; Emergency laparotomy ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Language	English
Publishing date	2024-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Chest CT Findings after 4 Months from the Onset of COVID-19 Pneumonia: A Case Series

Urciuoli, Luigi Guerriero Elvira

Diagnostics

Abstract: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Although the reference standard for SARS-CoV-2 diagnosis is real-time reverse transcription polymerase chain reaction ( ...

Abstract	Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Although the reference standard for SARS-CoV-2 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR), computed tomography (CT) is recommended for both initial evaluation and follow-up There is a growing body of published evidence about CT evolution during the course of COVID-19 pneumonia Here, we report six confirmed cases of COVID-19 patients who underwent unenhanced chest CT on admission and after 4 months from the onset of symptoms Chest-CT at first admission showed the typical CT features of COVID-19 Interestingly, the follow-up CT revealed the persistence of lung abnormalities in five cases even if all the patients were completely asymptomatic Further studies are needed for a comprehensive understanding of the disease progression and the resulting late imaging modifications
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #896565
Database	COVID19

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Article ; Online: Chest CT Findings after 4 Months from the Onset of COVID-19 Pneumonia

Luigi Urciuoli / Elvira Guerriero

Diagnostics, Vol 10, Iss 899, p

A Case Series

2020 Volume 899

Abstract	Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the reference standard for SARS-CoV-2 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR), computed tomography (CT) is recommended for both initial evaluation and follow-up. There is a growing body of published evidence about CT evolution during the course of COVID-19 pneumonia. Here, we report six confirmed cases of COVID-19 patients who underwent unenhanced chest CT on admission and after 4 months from the onset of symptoms. Chest-CT at first admission showed the typical CT features of COVID-19. Interestingly, the follow-up CT revealed the persistence of lung abnormalities in five cases even if all the patients were completely asymptomatic. Further studies are needed for a comprehensive understanding of the disease progression and the resulting late imaging modifications.
Keywords	COVID-19 ; chest CT ; follow-up ; 4 months ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2020-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Acute Ischemic Hemorrhagic Stroke in Two COVID-19 Patients.

Urciuoli, Luigi / Guerriero, Elvira / Musto, Lanfranco

Japanese journal of infectious diseases

2020 Volume 74, Issue 3, Page(s) 249–251

Abstract: Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). First identified in December 2019, in Wuhan, China, it has since become a global pandemic. Complications of COVID-19 are not limited to the ...

Abstract	Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). First identified in December 2019, in Wuhan, China, it has since become a global pandemic. Complications of COVID-19 are not limited to the pulmonary system, but also include neurologic manifestations such as stroke. We report two cases of coincidental presentation of COVID-19 and cerebrovascular accident. Further studies are needed for a comprehensive understanding of the neurological pathology of COVID-19 and its effects on the nervous system, but stroke teams should be wary of the fact that COVID-19 patients may present with cerebrovascular accidents.
Keywords	covid19
Language	English
Publishing date	2020-10-30
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1478383-6
ISSN	1884-2836 ; 1344-6304
ISSN (online)	1884-2836
ISSN	1344-6304
DOI	10.7883/yoken.JJID.2020.448
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Involvement of the Mediastinal Subpleural Pulmonary Parenchyma on Chest CT in COVID-19 patients: A Case Series.

Urciuoli, Luigi / Guerriero, Elvira / Musto, Lanfranco

Journal of radiology case reports

2020 Volume 14, Issue 11, Page(s) 1–15

Abstract: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). First identified in December 2019 in Wuhan, China, it has since become a global pandemic. Although the reference ... ...

Abstract	Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). First identified in December 2019 in Wuhan, China, it has since become a global pandemic. Although the reference standard for SARS-CoV-2 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR), computed tomography (CT) is recommended for both initial evaluation and follow-up. The CT findings in COVID-19 are varied, but typical ground-glass opacities are usually reported to occupy a peripheral costal subpleural distribution. Here we report eight confirmed COVID-19 cases who underwent clinical evaluation, laboratory testing, and unenhanced chest CT. In all patients, chest CT showed the presence of ground-glass opacities in the mediastinal subpleural parenchyma. While these cases also showed the typical CT features of COVID-19, involvement of the mediastinal subpleural parenchyma should not lower the index of suspicion for COVID-19.
MeSH term(s)	Aged ; Aged, 80 and over ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/epidemiology ; Female ; Humans ; Lung/diagnostic imaging ; Lung Diseases/diagnosis ; Lung Diseases/etiology ; Male ; Middle Aged ; Pandemics ; Retrospective Studies ; SARS-CoV-2 ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2020-11-30
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2586384-8
ISSN	1943-0922 ; 1943-0922
ISSN (online)	1943-0922
ISSN	1943-0922
DOI	10.3941/jrcr.v14i11.3974
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Novel Microwave Resonant Sensor for Measuring Cancer Cell Line Aggressiveness.

D'Alvia, Livio / Carraro, Serena / Peruzzi, Barbara / Urciuoli, Enrica / Palla, Luigi / Del Prete, Zaccaria / Rizzuto, Emanuele

Sensors (Basel, Switzerland)

2022 Volume 22, Issue 12

Abstract: The measurement of biological tissues' dielectric properties plays a crucial role in determining the state of health, and recent studies have reported microwave biosensing to be an innovative method with great potential in this field. Research has been ... ...

Abstract	The measurement of biological tissues' dielectric properties plays a crucial role in determining the state of health, and recent studies have reported microwave biosensing to be an innovative method with great potential in this field. Research has been conducted from the tissue level to the cellular level but, to date, cellular adhesion has never been considered. In addition, conventional systems for diagnosing tumor aggressiveness, such as a biopsy, are rather expensive and invasive. Here, we propose a novel microwave approach for biosensing adherent cancer cells with different malignancy degrees. A circular patch resonator was designed adjusting its structure to a standard Petri dish and a network analyzer was employed. Then, the resonator was realized and used to test two groups of different cancer cell lines, based on various tumor types and aggressiveness: low- and high-aggressive osteosarcoma cell lines (SaOS-2 and 143B, respectively), and low- and high-aggressive breast cancer cell lines (MCF-7 and MDA-MB-231, respectively). The experimental results showed that the sensitivity of the sensor was high, in particular when measuring the resonant frequency. Finally, the sensor showed a good ability to distinguish low-metastatic and high-metastatic cells, paving the way to the development of more complex measurement systems for noninvasive tissue diagnosis.
MeSH term(s)	Cell Adhesion ; Humans ; MCF-7 Cells ; Microwaves ; Neoplasms
Language	English
Publishing date	2022-06-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s22124383
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Oleuropein from olive leaf extracts and extra-virgin olive oil provides distinctive phenolic profiles and modulation of microbiota in the large intestine.

Rocchetti, Gabriele / Luisa Callegari, Maria / Senizza, Alice / Giuberti, Gianluca / Ruzzolini, Jessica / Romani, Annalisa / Urciuoli, Silvia / Nediani, Chiara / Lucini, Luigi

Food chemistry

2022 Volume 380, Page(s) 132187

Abstract: The interest in the modulation of gut microbiota by polyphenols from olives and derived products is increasing. In this work, phenolic leaf extracts (PLE) were in vitro faecal fermented to evaluate the changes in phenolic profiles and the impact on ... ...

Abstract	The interest in the modulation of gut microbiota by polyphenols from olives and derived products is increasing. In this work, phenolic leaf extracts (PLE) were in vitro faecal fermented to evaluate the changes in phenolic profiles and the impact on microbiota, using a commercial extra-virgin olive oil (EVOO) as reference. The in vitro fermentation decreased oleuropein content in PLE, determining an increase of hydroxytyrosol and other phenolic metabolites. An increase (p < 0.05) of hydroxytyrosol (LogFC = 6.02; VIP score = 1.05) was also observed in fermented EVOO. Besides, PLE significantly (p < 0.05) changed amino acids (LogFC = 6.1) and fatty acids (LogFC = 5.9) profile of the faeces. Metagenomic sequencing revealed that Coriobacteriaceae at the family level, and Collinsella at the genus level, were the most affected by PLE fermentation. These findings support the modulation of the gut microbiota exerted by phenolics from PLE and EVOO.
MeSH term(s)	Intestine, Large ; Iridoid Glucosides ; Microbiota ; Olea ; Olive Oil ; Plant Extracts ; Plant Oils
Chemical Substances	Iridoid Glucosides ; Olive Oil ; Plant Extracts ; Plant Oils ; oleuropein (2O4553545L) ; olive leaf extract (MJ95C3OH47)
Language	English
Publishing date	2022-01-21
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2022.132187
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Acute Ischemic and Hemorrhagic Stroke in Two Covid-19 Patients

Urciuoli, Luigi / Guerriero, Elvira / Musto, Lanfranco

Jpn. j. infect. dis

Abstract: Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). First identified in December 2019 in Wuhan, China, it has since become a global pandemic. Complications of COVID-19 are not limited to the ... ...

Abstract	Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). First identified in December 2019 in Wuhan, China, it has since become a global pandemic. Complications of COVID-19 are not limited to the pulmonary system, but include also neurologic manifestations, such as stroke. We report two cases with coincident presentation of COVID-19 and cerebrovascular accident. Further studies are needed for a comprehensive understanding of the neurological pathology of COVID-19 and its effects on the nervous system, but stroke teams should be wary of the fact that COVID-19 patients can present with cerebrovascular accidents.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #902964
Database	COVID19

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