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Article ; Online: Plasticity of Dopaminergic Phenotype and Locomotion in Larval Zebrafish Induced by Brain Excitability Changes during the Embryonic Period.

Bataille, Sandrine / Jalaber, Hadrien / Colin, Ingrid / Remy, Damien / Affaticati, Pierre / Froc, Cynthia / Levraud, Jean-Pierre / Vernier, Philippe / Demarque, Michaël

eNeuro

2023 Volume 10, Issue 6

Abstract: During the embryonic period, neuronal communication starts before the establishment of the synapses with alternative forms of neuronal excitability, called here embryonic neural excitability (ENE). ENE has been shown to modulate the unfolding of ... ...

Abstract	During the embryonic period, neuronal communication starts before the establishment of the synapses with alternative forms of neuronal excitability, called here embryonic neural excitability (ENE). ENE has been shown to modulate the unfolding of development transcriptional programs, but the global consequences for developing organisms are not all understood. Here, we monitored calcium (Ca
MeSH term(s)	Animals ; Zebrafish ; Dopamine ; Larva ; Locomotion/physiology ; Brain ; Phenotype ; Dopaminergic Neurons
Chemical Substances	Dopamine (VTD58H1Z2X)
Language	English
Publishing date	2023-06-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2800598-3
ISSN	2373-2822 ; 2373-2822
ISSN (online)	2373-2822
ISSN	2373-2822
DOI	10.1523/ENEURO.0320-21.2023
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Chest ultrasound findings in usual interstitial pneumonia patterns: a pilot study.

Joërg, Laetitia / Trouillon, Tiffany / Jalaber, Carole / Court Fortune, Isabelle / Luchez, Antoine / Boutet, Claire / Vergnon, Jean Michel / Bertoletti, Laurent / Froudarakis, Marios E

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

2022 Volume 93, Issue 2

Abstract: It is unknown what role chest ultrasound plays in distinguishing the various usual interstitial pneumonia (UIP) patterns of high-resolution chest tomography (HRCT). The purpose of this study was to see if there was a link between the results of chest ... ...

Abstract	It is unknown what role chest ultrasound plays in distinguishing the various usual interstitial pneumonia (UIP) patterns of high-resolution chest tomography (HRCT). The purpose of this study was to see if there was a link between the results of chest ultrasound (u/s) and HRCT in patients with idiopathic pulmonary fibrosis (IPF). We performed chest u/s in 16 patients with UIP and probable UIP patterns to indeterminate UIP and alternative diagnosis patterns in this single center prospective study to determine any possible relationship with the HRCT findings. A chest radiologist reviewed each HRCT to determine the pattern in accordance with the American Thoracic Society (ATS) / European Respiratory Society (ERS) Guidelines. The local multidisciplinary committee validated the patients' diagnoses before they were included. When compared to the indeterminate for UIP or alternative diagnosis pattern group, there was a trend (p=0.07) toward the presence of more B lines in UIP or probable UIP patterns. There was no statistically significant difference in the presence of small, large, white lung, or pleural line thickening >5mm. Subgroup analysis revealed that patients with honeycombing were more likely to have a fragmented pleural line (p=0.04). To summarize, in our pilot study, chest u/s appears unable to differentiate UIP and probable UIP patterns from indeterminate UIP and alternative diagnosis patterns. However, it appears that this technique can be used to recognize the honeycombing pattern.
MeSH term(s)	Humans ; Lung/diagnostic imaging ; Pilot Projects ; Prospective Studies ; Idiopathic Pulmonary Fibrosis/diagnostic imaging ; Probability ; Retrospective Studies
Language	English
Publishing date	2022-09-07
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1160940-0
ISSN	1122-0643 ; 1120-0391
ISSN	1122-0643 ; 1120-0391
DOI	10.4081/monaldi.2022.2356
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Zs.B 65: Show issues

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Article ; Online: Chest CT in COVID-19 pneumonia: A review of current knowledge.

Jalaber, C / Lapotre, T / Morcet-Delattre, T / Ribet, F / Jouneau, S / Lederlin, M

Diagnostic and interventional imaging

2020 Volume 101, Issue 7-8, Page(s) 431–437

Abstract: The current COVID-19 pandemic has highlighted the essential role of chest computed tomography (CT) examination in patient triage in the emergency departments, allowing them to be referred to "COVID" or "non-COVID" wards. Initial chest CT examination must ...

Abstract	The current COVID-19 pandemic has highlighted the essential role of chest computed tomography (CT) examination in patient triage in the emergency departments, allowing them to be referred to "COVID" or "non-COVID" wards. Initial chest CT examination must be performed without intravenous administration of iodinated contrast material, but contrast material administration is required when pulmonary embolism is suspected, which seems to be frequent in severe forms of the disease. Typical CT features consist of bilateral ground-glass opacities with peripheral, posterior and basal predominance. Lung disease extent on CT correlates with clinical severity. Artificial intelligence could assist radiologists for diagnosis and prognosis evaluation.
MeSH term(s)	Adult ; Aged ; Artificial Intelligence ; Betacoronavirus ; COVID-19 ; Child ; Contrast Media ; Coronavirus Infections/complications ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/epidemiology ; Female ; Hospital Units/classification ; Hospitalization ; Humans ; Lung/diagnostic imaging ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/epidemiology ; Pregnancy ; Pulmonary Embolism/diagnostic imaging ; Pulmonary Embolism/etiology ; Radiography, Thoracic/methods ; SARS-CoV-2 ; Severity of Illness Index ; Tomography, X-Ray Computed ; Triage
Chemical Substances	Contrast Media
Keywords	covid19
Language	English
Publishing date	2020-06-11
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	2648283-6
ISSN	2211-5684 ; 2211-5684
ISSN (online)	2211-5684
ISSN	2211-5684
DOI	10.1016/j.diii.2020.06.001
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Article ; Online: Is COVID-19 pneumonia differentiable from other viral pneumonia on CT scan?

Jalaber, C / Chassagnon, G / Hani, C / Dangeard, S / Babin, M / Launay, O / Revel, M-P

Respiratory medicine and research

2021 Volume 79, Page(s) 100824

MeSH term(s)	COVID-19/diagnostic imaging ; Clinical Competence ; Confidence Intervals ; Diagnosis, Differential ; France ; Humans ; Pneumonia, Viral/diagnostic imaging ; Radiologists ; Sensitivity and Specificity ; Tomography, X-Ray Computed
Language	English
Publishing date	2021-04-27
Publishing country	France
Document type	Journal Article
ISSN	2590-0412
ISSN (online)	2590-0412
DOI	10.1016/j.resmer.2021.100824
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Article ; Online: Differentiating tracheobronchial involvement in granulomatosis with polyangiitis and relapsing polychondritis on chest CT: a cohort study.

Jalaber, Carole / Puéchal, Xavier / Saab, Ines / Canniff, Emma / Terrier, Benjamin / Mouthon, Luc / Cabanne, Eglantine / Mghaieth, Sandra / Revel, Marie-Pierre / Chassagnon, Guillaume

Arthritis research & therapy

2022 Volume 24, Issue 1, Page(s) 241

Abstract: Background: In patients with tracheobronchial involvement, the differential diagnosis between granulomatosis with polyangiitis (GPA) and relapsing polychondritis (RP) can be challenging. The aim of this study was to describe the characteristics of ... ...

Abstract	Background: In patients with tracheobronchial involvement, the differential diagnosis between granulomatosis with polyangiitis (GPA) and relapsing polychondritis (RP) can be challenging. The aim of this study was to describe the characteristics of airway abnormalities on chest computed tomography (CT) in patients with GPA or RP and to determine whether specific imaging criteria could be used to differentiate them. Methods: GPA and RP patients with tracheobronchial involvement referred to a national referral center from 2008 to 2020 were evaluated. Their chest CT images were reviewed by two radiologists who were blinded to the final diagnosis in order to analyze the characteristics of airway involvement. The association between imaging features and a diagnosis of GPA rather than RP was analyzed using a generalized linear regression model. Results: Chest CTs from 26 GPA and 19 RP patients were analyzed. Involvement of the subglottic trachea (odds ratio for GPA=28.56 [95% CI: 3.17; 847.63]; P=0.001) and extensive airway involvement (odds ratio for GPA=0.02 [95% CI: 0.00; 0.43]; P=0.008) were the two independent CT features that differentiated GPA from RP in multivariate analysis. Tracheal thickening sparing the posterior membrane was significantly associated to RP (odds ratio for GPA=0.09 [95% CI: 0.02; 0.39]; P=0.003) but only in the univariate analysis and suffered from only moderate interobserver agreement (kappa=0.55). Tracheal calcifications were also associated with RP only in the univariate analysis (odds ratio for GPA=0.21 [95% CI: 0.05; 0.78]; P=0.045). Conclusion: The presence of subglottic involvement and diffuse airway involvement are the two most relevant criteria in differentiating between GPA and RP on chest CT. Although generally considered to be a highly suggestive sign of RP, posterior tracheal membrane sparing is a nonspecific and an overly subjective sign.
MeSH term(s)	Humans ; Polychondritis, Relapsing/complications ; Polychondritis, Relapsing/diagnostic imaging ; Granulomatosis with Polyangiitis/diagnosis ; Granulomatosis with Polyangiitis/diagnostic imaging ; Cohort Studies ; Tomography, X-Ray Computed ; Respiratory System
Language	English
Publishing date	2022-10-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2107602-9
ISSN	1478-6362 ; 1478-6354
ISSN (online)	1478-6362
ISSN	1478-6354
DOI	10.1186/s13075-022-02935-2
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Article ; Online: Chest CT in COVID-19 pneumonia

Jalaber, C. / Lapotre, T. / Morcet-Delattre, T. / Ribet, F. / Jouneau, S. / Lederlin, M.

Diagnostic and Interventional Imaging

A review of current knowledge

2020 Volume 101, Issue 7-8, Page(s) 431–437

Keywords	Radiological and Ultrasound Technology ; Radiology Nuclear Medicine and imaging ; General Medicine ; covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
ZDB-ID	2648283-6
ISSN	2211-5684
ISSN	2211-5684
DOI	10.1016/j.diii.2020.06.001
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Role of upfront CT pulmonary angiography at admission in COVID-19 patients.

Jalaber, Carole / Revel, Marie-Pierre / Chassagnon, Guillaume / Bajeux, Emma / Lapotre, Thibaut / Croisille, Pierre / Lederlin, Mathieu

Thrombosis research

2020 Volume 196, Page(s) 138–140

MeSH term(s)	Angiography ; COVID-19 ; Humans ; Lung ; Pandemics ; Patients ; Role ; SARS-CoV-2 ; Thrombophilia
Keywords	covid19
Language	English
Publishing date	2020-08-25
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	121852-9
ISSN	1879-2472 ; 0049-3848
ISSN (online)	1879-2472
ISSN	0049-3848
DOI	10.1016/j.thromres.2020.08.037
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Zs.A 863: Show issues

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Article: Chest CT in COVID-19 pneumonia: A review of current knowledge

Jalaber, C / Lapotre, T / Morcet-Delattre, T / Ribet, F / Jouneau, S / Lederlin, M

Diagn Interv Imaging

Abstract	The current COVID-19 pandemic has highlighted the essential role of chest computed tomography (CT) examination in patient triage in the emergency departments, allowing them to be referred to "COVID" or "non-COVID" wards. Initial chest CT examination must be performed without intravenous administration of iodinated contrast material, but contrast material administration is required when pulmonary embolism is suspected, which seems to be frequent in severe forms of the disease. Typical CT features consist of bilateral ground-glass opacities with peripheral, posterior and basal predominance. Lung disease extent on CT correlates with clinical severity. Artificial intelligence could assist radiologists for diagnosis and prognosis evaluation.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #593504
Database	COVID19

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Article ; Online: Chest CT in COVID-19 pneumonia

Jalaber, C / Lapotre, T / Morcet-Delattre, T / Ribet, F / Jouneau, Stéphane / Lederlin, M.

ISSN: 2211-5684 ; EISSN: 2211-5684 ; Diagnostic and Interventional Imaging ; https://hal.archives-ouvertes.fr/hal-02887405 ; Diagnostic and Interventional Imaging, Elsevier, 2020, 101 (7-8), pp.431-437. ⟨10.1016/j.diii.2020.06.001⟩

A review of current knowledge

2020

Abstract: International audience ... The current COVID-19 pandemic has highlighted the essential role of chest computed tomography (CT) examination in patient triage in the emergency departments, allowing them to be referred to "COVID" or "non-COVID" wards. Initial ... ...

Abstract	International audience The current COVID-19 pandemic has highlighted the essential role of chest computed tomography (CT) examination in patient triage in the emergency departments, allowing them to be referred to "COVID" or "non-COVID" wards. Initial chest CT examination must be performed without intravenous administration of iodinated contrast material, but contrast material administration is required when pulmonary embolism is suspected, which seems to be frequent in severe forms of the disease. Typical CT features consist of bilateral ground-glass opacities with peripheral, posterior and basal predominance. Lung disease extent on CT correlates with clinical severity. Artificial intelligence could assist radiologists for diagnosis and prognosis evaluation.
Keywords	COVID-19 ; Pulmonary embolism ; Severe acute respiratory syndrome coronavirus 2 ; Tomography ; X-ray computed ; [SDV.IB]Life Sciences [q-bio]/Bioengineering ; covid19
Language	English
Publisher	HAL CCSD
Publishing country	fr
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Chest CT in COVID-19 pneumonia

Jalaber, C / Lapotre, T / Morcet-Delattre, T / Ribet, F / Jouneau, Stéphane / Lederlin, M.

A review of current knowledge

2020

Abstract	International audience The current COVID-19 pandemic has highlighted the essential role of chest computed tomography (CT) examination in patient triage in the emergency departments, allowing them to be referred to "COVID" or "non-COVID" wards. Initial chest CT examination must be performed without intravenous administration of iodinated contrast material, but contrast material administration is required when pulmonary embolism is suspected, which seems to be frequent in severe forms of the disease. Typical CT features consist of bilateral ground-glass opacities with peripheral, posterior and basal predominance. Lung disease extent on CT correlates with clinical severity. Artificial intelligence could assist radiologists for diagnosis and prognosis evaluation.
Keywords	COVID-19 ; Pulmonary embolism ; Severe acute respiratory syndrome coronavirus 2 ; Tomography ; X-ray computed ; [SDV.IB]Life Sciences [q-bio]/Bioengineering ; covid19
Language	English
Publisher	HAL CCSD
Publishing country	fr
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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