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Article: Case report: Dihydropyridine receptor (

Aburahma, Samah K / Rousan, Liqa A / Shboul, Mohammad / Biella, Fabio / Lucchiari, Sabrina / Comi, Giacomo Pietro / Meola, Giovanni / Pagliarani, Serena

Frontiers in neurology

2024 Volume 15, Page(s) 1359479

Abstract: Introduction: CACNA1S: Clinical description: Both sisters had neonatal onset hypotonia, muscle weakness, and delayed walking. Episodic weakness started in infancy and continued thereafter, provoked mostly by cold exposure. Muscle imaging revealed fat ...

Abstract	Introduction: CACNA1S Clinical description: Both sisters had neonatal onset hypotonia, muscle weakness, and delayed walking. Episodic weakness started in infancy and continued thereafter, provoked mostly by cold exposure. Muscle imaging revealed fat replacement of gluteus maximus muscles. Next generation sequencing found the missense p.Cys944Tyr variant and the novel splicing variant c.3526-2A>G in Conclusion: This novel phenotype supports the notion that there are age related differences in the clinical expression of
Language	English
Publishing date	2024-02-15
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2024.1359479
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Article ; Online: Retro-psoas muscle vermiform appendix: an unusual location.

Rousan, Liqa A / Jibril, Mohammad I

Surgical and radiologic anatomy : SRA

2020 Volume 42, Issue 10, Page(s) 1259–1261

Abstract: The vermiform appendix is considered the most mobile organ in the human body. Due to its various positions in the abdomen and pelvis, it may result in confusion in diagnosis to the surgeons when it becomes inflamed. Atypical locations of the appendix ... ...

Abstract	The vermiform appendix is considered the most mobile organ in the human body. Due to its various positions in the abdomen and pelvis, it may result in confusion in diagnosis to the surgeons when it becomes inflamed. Atypical locations of the appendix have been reported previously in the literature. We report an unusual location of the vermiform appendix in the right retro-psoas muscle space that was incidentally discovered in a male patient who was involved in a road traffic accident.
MeSH term(s)	Accidents, Traffic ; Anatomic Variation ; Appendicitis/diagnosis ; Appendix/abnormalities ; Appendix/diagnostic imaging ; Humans ; Incidental Findings ; Male ; Psoas Muscles/diagnostic imaging ; Tomography, X-Ray Computed ; Young Adult
Language	English
Publishing date	2020-04-27
Publishing country	Germany
Document type	Case Reports ; Journal Article
ZDB-ID	632839-8
ISSN	1279-8517 ; 0930-312X ; 0930-1038
ISSN (online)	1279-8517
ISSN	0930-312X ; 0930-1038
DOI	10.1007/s00276-020-02477-9
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Article ; Online: Fatty Liver and Colonic Diverticulosis in an Obese Child.

Rousan, Liqa A / Al-Qaralleh, Mohammed A / Rousan, Nour A / Al-Quran, Thekraiat M / Bataineh, Ziad A

Clinical pediatrics

2022 Volume 62, Issue 3, Page(s) 195–197

MeSH term(s)	Humans ; Child ; Diverticulosis, Colonic/complications ; Diverticulosis, Colonic/diagnosis ; Fatty Liver ; Obesity/complications ; Colonoscopy
Language	English
Publishing date	2022-08-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	207678-0
ISSN	1938-2707 ; 0009-9228
ISSN (online)	1938-2707
ISSN	0009-9228
DOI	10.1177/00099228221119257
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Article ; Online: Chest x-ray findings and temporal lung changes in patients with COVID-19 pneumonia.

Rousan, Liqa A / Elobeid, Eyhab / Karrar, Musaab / Khader, Yousef

BMC pulmonary medicine

2020 Volume 20, Issue 1, Page(s) 245

Abstract: Background: Chest CT scan and chest x-rays show characteristic radiographic findings in patients with COVID-19 pneumonia. Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia. The study aims at describing the chest x- ... ...

Abstract	Background: Chest CT scan and chest x-rays show characteristic radiographic findings in patients with COVID-19 pneumonia. Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia. The study aims at describing the chest x-ray findings and temporal radiographic changes in COVID-19 patients. Methods: From March 15 to April 20, 2020 patients with positive reverse transcription polymerase chain reaction (RT-PCR) for COVID-19 were retrospectively studied. Patients' demographics, clinical characteristics, and chest x-ray findings were reported. Radiographic findings were correlated with the course of the illness and patients' symptoms. Results: A total of 88 patients (50 (56.8%) females and 38 (43.2%) males) were admitted to the hospital with confirmed COVID-19. Their age ranged from 3 to 80 years (35.2 ± 18.2 years). 48/88 (45%) were symptomatic, only 13/88 (45.5%) showed abnormal chest x-ray findings. A total of 190 chest x-rays were obtained for the 88 patients with a total of 59/190 (31%) abnormal chest x-rays. The most common finding on chest x-rays was peripheral ground glass opacities (GGO) affecting the lower lobes. In the course of illness, the GGO progressed into consolidations peaking around 6-11 days (GGO 70%, consolidations 30%). The consolidations regressed into GGO towards the later phase of the illness at 12-17 days (GGO 80%, consolidations 10%). There was increase in the frequency of normal chest x-rays from 9% at days 6-11 up to 33% after 18 days indicating a healing phase. The majority (12/13, 92.3%) of patients with abnormal chest x-rays were symptomatic (P = 0.005). Conclusion: Almost half of patients with COVID-19 have abnormal chest x-ray findings with peripheral GGO affecting the lower lobes being the most common finding. Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; COVID-19 ; Child ; Child, Preschool ; Coronavirus Infections/diagnostic imaging ; Female ; Humans ; Lung/diagnostic imaging ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Radiography, Thoracic ; Retrospective Studies ; Time Factors ; Tomography, X-Ray Computed ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-09-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2059871-3
ISSN	1471-2466 ; 1471-2466
ISSN (online)	1471-2466
ISSN	1471-2466
DOI	10.1186/s12890-020-01286-5
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Article ; Online: Chest x-ray findings and temporal lung changes in patients with COVID-19 pneumonia

Liqa A. Rousan / Eyhab Elobeid / Musaab Karrar / Yousef Khader

BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-

2020 Volume 9

Abstract: Abstract Background Chest CT scan and chest x-rays show characteristic radiographic findings in patients with COVID-19 pneumonia. Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia. The study aims at describing the ... ...

Abstract	Abstract Background Chest CT scan and chest x-rays show characteristic radiographic findings in patients with COVID-19 pneumonia. Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia. The study aims at describing the chest x-ray findings and temporal radiographic changes in COVID-19 patients. Methods From March 15 to April 20, 2020 patients with positive reverse transcription polymerase chain reaction (RT-PCR) for COVID-19 were retrospectively studied. Patients’ demographics, clinical characteristics, and chest x-ray findings were reported. Radiographic findings were correlated with the course of the illness and patients’ symptoms. Results A total of 88 patients (50 (56.8%) females and 38 (43.2%) males) were admitted to the hospital with confirmed COVID-19. Their age ranged from 3 to 80 years (35.2 ± 18.2 years). 48/88 (45%) were symptomatic, only 13/88 (45.5%) showed abnormal chest x-ray findings. A total of 190 chest x-rays were obtained for the 88 patients with a total of 59/190 (31%) abnormal chest x-rays. The most common finding on chest x-rays was peripheral ground glass opacities (GGO) affecting the lower lobes. In the course of illness, the GGO progressed into consolidations peaking around 6–11 days (GGO 70%, consolidations 30%). The consolidations regressed into GGO towards the later phase of the illness at 12–17 days (GGO 80%, consolidations 10%). There was increase in the frequency of normal chest x-rays from 9% at days 6–11 up to 33% after 18 days indicating a healing phase. The majority (12/13, 92.3%) of patients with abnormal chest x-rays were symptomatic (P = 0.005). Conclusion Almost half of patients with COVID-19 have abnormal chest x-ray findings with peripheral GGO affecting the lower lobes being the most common finding. Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia.
Keywords	Diseases of the respiratory system ; RC705-779 ; covid19
Subject code	610
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
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Article: Bilateral Congenital Diaphragm Agenesis in a Neonate with Hydrocephalus: Case Report.

Rousan, Liqa A / Al-Nussair, Bayan / Qudah, Heba Al / A Bataineh, Ziad

European journal of radiology open

2020 Volume 7, Page(s) 100270

Abstract: Congenital diaphragmatic hernia (CDH) is one of the most common anomalies in neonates. Diaphragmatic agenesis (DA) is rare and is considered at the extreme spectrum of CDH, it is associated with a higher rate of multiple anomalies. A male neonate with ... ...

Abstract	Congenital diaphragmatic hernia (CDH) is one of the most common anomalies in neonates. Diaphragmatic agenesis (DA) is rare and is considered at the extreme spectrum of CDH, it is associated with a higher rate of multiple anomalies. A male neonate with antenatal diagnosis of CDH and hydrocephalus was born at estimated gestational age of 36 + 4 weeks by emergency Caesarean section due to fetal distress. Chest x-ray showed a common pleuroperitoneal cavity with the liver, spleen, and stomach seen in the thoracic cavity suggesting the diagnosis of bilateral absence of the diaphragm, the neonate died after an hour and a half. DA associated with hydrocephalus has never been previously reported in the literature.
Language	English
Publishing date	2020-09-17
Publishing country	England
Document type	Case Reports
ISSN	2352-0477
ISSN	2352-0477
DOI	10.1016/j.ejro.2020.100270
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Article: The ability of digital breast tomosynthesis to reduce additional examinations in older women.

Gharaibeh, Maha / Alfwares, Ahmad Abu / Elobeid, Eyhab / Khasawneh, Ruba / Rousan, Liqa / El-Heis, Mwaffaq / Al-Jarrah, Mooath / Haj Hussein, Ahmed A / Altalhi, Maryam / Abualigah, Laith

Frontiers in medicine

2023 Volume 10, Page(s) 1276434

Abstract: Aims: To assess the diagnostic performance of digital breast tomosynthesis (DBT) in older women across varying breast densities and to compare its effectiveness for cancer detection with 2D mammography and ultrasound (U/S) for different breast density ... ...

Abstract	Aims: To assess the diagnostic performance of digital breast tomosynthesis (DBT) in older women across varying breast densities and to compare its effectiveness for cancer detection with 2D mammography and ultrasound (U/S) for different breast density categories. Furthermore, our study aimed to predict the potential reduction in unnecessary additional examinations among older women due to DBT. Methods: This study encompassed a cohort of 224 older women. Each participant underwent both 2D mammography and digital breast tomosynthesis examinations. Supplementary views were conducted when necessary, including spot compression and magnification, ultrasound, and recommended biopsies. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under the curve (AUC) were calculated for 2D mammography, DBT, and ultrasound. The impact of DBT on diminishing the need for supplementary imaging procedures was predicted through binary logistic regression. Results: In dense breast tissue, DBT exhibited notably heightened sensitivity and NPV for lesion detection compared to non-dense breasts (61.9% vs. 49.3%, Conclusion: Our findings indicate that among older women, DBT does not significantly decrease the requirement for further medical examinations.
Language	English
Publishing date	2023-11-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2023.1276434
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Article: Biochemical and Ultrasound Characteristics of Subclinical Hypothyroid Patients in North of Jordan: Who Was Treated?

Saadeh, Nesreen A / Saadeh, Rami / Rousan, Liqa A / Rawashdeh, Dalia / Obeidat, Aya / Saadeh, Abdullah M

International journal of general medicine

2020 Volume 13, Page(s) 305–310

Abstract: Background: Early diagnosis and management of subclinical hypothyroidism (SCH) are important to avoid the risk of developing overt hypothyroidism. This study aimed to evaluate patients with subclinical hypothyroidism (SCH), in regard to their ... ...

Abstract	Background: Early diagnosis and management of subclinical hypothyroidism (SCH) are important to avoid the risk of developing overt hypothyroidism. This study aimed to evaluate patients with subclinical hypothyroidism (SCH), in regard to their biochemical characteristics, and ultrasound features, and factors associated with initiating treatment for this condition. Methods: This was a retrospective study, which reviewed the data of patients who visited the Endocrinology clinic of a tertiary hospital in Jordan, King Abdullah University Hospital. Patients who visited the clinic with SCH over 1 year, Jan 2016-Dec 2016, were included. The charts were reviewed again 2 years later to check patients who started L-thyroxine for the different indications of treatment of SCH. Thyroid function tests (free T3, free T4, and TSH) and thyroid peroxidase antibodies (TPO-Ab) were found to be measured for all cases (n=287), among whom, thyroid ultrasound was done for 43 patients. Results: Most patients were females (88.1%). Mean age was 42.36 (±15.36 years). Positive TPO-Ab status was associated with higher TSH (p=0.056), lower free T4 levels (p= 0.012), and more patients treated with L- thyroxine for SCH in 2 years (p=0.001). On ultrasound, hypoechogenicity was more predominant among TPO-Ab positive patients than TPO-Ab negative patients (78% vs 30%). Conclusion: SCH patients with positive TPO-Abs were more likely to be treated for this condition based on the various indications, and more likely to have had hypoechogenicity on ultrasound. Hence, thyroid ultrasonography and TPO-Ab status should be implemented early in evaluating and treating patients with SCH.
Language	English
Publishing date	2020-06-15
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2452220-X
ISSN	1178-7074
ISSN	1178-7074
DOI	10.2147/IJGM.S252114
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Article ; Online: Myxoma of the renal pelvis masquerading pelviureteric stenosis: conservative limited resection with renal preservation: case presentation and literature review.

Aldaoud, Najla / Hallak, Amer / Rousan, Liqa A / Halalsheh, Omar / Darayseh, Bashar / Al-Abbadi, Mousa A

BMC urology

2020 Volume 20, Issue 1, Page(s) 80

Abstract: Background: Myxoma is a relatively rare mesenchymal tumor seen mainly in the heart and skin. Renal myxomas in particular are exceptionally rare where only 17 cases were previously reported in the English Language literature. Only 2 of the 17 reported ... ...

Abstract	Background: Myxoma is a relatively rare mesenchymal tumor seen mainly in the heart and skin. Renal myxomas in particular are exceptionally rare where only 17 cases were previously reported in the English Language literature. Only 2 of the 17 reported cases were located in the renal sinus/pelvis. Case presentation: This is a case of an 18-year-old male patient who complained of right, colicky flank pain associated with abdominal pain and discomfort. Imaging findings revealed right kidney hydronephrosis with a provisional diagnosis of pelviureteric junction (PUJ) stenosis. On computed tomography, there was a very faint thin walled mass abutting the calyces, camouflaged within the dilated renal pelvis. During surgery, a polypoid mass was found at the pelviureteric junction, causing the obstruction. Histological examination showed a hypocellular, paucivascular myxoid neoplasm, with few spindle cells displaying serpentine nuclei and inconspicuous nucleoli. The tumor cells expressed immunoreactivity for vimentin, but not for S100, CD34, actin, or desmin. This will qualify as the third case of renal pelvis myxoma. Conclusion: Myxomas in the renal pelvis/sinus are extremely rare and can present with hydronephrosis and subtle radiological findings mimicking a PUJ stenosis. Being aware of this entity can save the patient unnecessary nephrectomy with possible preservation of the kidney.
MeSH term(s)	Adolescent ; Constriction, Pathologic ; Diagnosis, Differential ; Humans ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/surgery ; Kidney Pelvis ; Male ; Myxoma/diagnosis ; Myxoma/surgery ; Nephrectomy/methods ; Organ Sparing Treatments ; Ureteral Obstruction/diagnosis
Language	English
Publishing date	2020-06-30
Publishing country	England
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2059857-9
ISSN	1471-2490 ; 1471-2490
ISSN (online)	1471-2490
ISSN	1471-2490
DOI	10.1186/s12894-020-00657-8
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Article ; Online: Bilateral Congenital Diaphragm Agenesis in a Neonate with Hydrocephalus

Liqa A Rousan / Bayan Al-Nussair / Heba Al Qudah / Ziad A Bataineh

European Journal of Radiology Open, Vol 7, Iss , Pp 100270- (2020)

Case Report

2020

Abstract	Congenital diaphragmatic hernia (CDH) is one of the most common anomalies in neonates. Diaphragmatic agenesis (DA) is rare and is considered at the extreme spectrum of CDH, it is associated with a higher rate of multiple anomalies.A male neonate with antenatal diagnosis of CDH and hydrocephalus was born at estimated gestational age of 36 + 4 weeks by emergency Caesarean section due to fetal distress. Chest x-ray showed a common pleuroperitoneal cavity with the liver, spleen, and stomach seen in the thoracic cavity suggesting the diagnosis of bilateral absence of the diaphragm, the neonate died after an hour and a half. DA associated with hydrocephalus has never been previously reported in the literature.
Keywords	congenital diaphragm hernia ; diaphragm agenesis ; neonates ; hydrocephalus ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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