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Article ; Online: Evaluating pesticide degradation in artificial wetlands with compound-specific isotope analysis: A case study with the fungicide dimethomorph.

Gilevska, Tetyana / Payraudeau, Sylvain / Imfeld, Gwenaël

2023 Volume 900, Page(s) 165767

Abstract: Pesticide degradation in wetland systems intercepting agricultural runoff is often overlooked and mixed with other dissipation processes when assessing pesticide concentrations alone. This study focused on the potential of compound-specific isotope ... ...

Abstract	Pesticide degradation in wetland systems intercepting agricultural runoff is often overlooked and mixed with other dissipation processes when assessing pesticide concentrations alone. This study focused on the potential of compound-specific isotope analysis (CSIA) to estimate pesticide degradation in a stormwater wetland receiving pesticide runoff from a vineyard catchment. The fungicide dimethomorph (DIM), with diastereoisomers E and Z, was the prevalent pesticide in the runoff entering the wetland from June to September 2020. DIM Z, the most commonly detected isomer, exhibited a significant change (Δ(
MeSH term(s)	Pesticides/analysis ; Fungicides, Industrial/analysis ; Wetlands ; Carbon Isotopes/analysis ; Biodegradation, Environmental ; Plants ; Water Pollutants, Chemical/analysis ; Water/analysis
Chemical Substances	Pesticides ; Fungicides, Industrial ; dimethomorph (3EXL2158GV) ; Carbon Isotopes ; Water Pollutants, Chemical ; Water (059QF0KO0R)
Language	English
Publishing date	2023-07-26
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.165767
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Zs.A 949: Show issues

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Article ; Online: Emissions of the Urban Biocide Terbutryn from Facades: The Contribution of Transformation Products.

Junginger, Tobias / Payraudeau, Sylvain / Imfeld, Gwenaël

Environmental science & technology

2023 Volume 57, Issue 38, Page(s) 14319–14329

Abstract: Biocides are added to facade paints and renders to prevent algal and fungal growth. The emissions of biocides and their transformation products from building facades during wind-driven rain can contaminate surface waters, soil, and groundwater. Although ... ...

Abstract	Biocides are added to facade paints and renders to prevent algal and fungal growth. The emissions of biocides and their transformation products from building facades during wind-driven rain can contaminate surface waters, soil, and groundwater. Although the emissions of biocide transformation products may be higher than those of the parent biocide, knowledge of the emissions of transformation products over time is scarce. Combining field- and lab-scale experiments, we showed that solar irradiation on facades controls the formation of transformation products and can be used with runoff volume to estimate the long-term emissions of terbutryn transformation products from facades. The slow (
MeSH term(s)	Carbon Isotopes ; Chemical Fractionation ; Diffusion ; Groundwater
Chemical Substances	terbutryne (ZXL474TLFP) ; Carbon Isotopes
Language	English
Publishing date	2023-09-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.2c08192
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Article ; Online: Transformation and stable isotope fractionation of the urban biocide terbutryn during biodegradation, photodegradation and abiotic hydrolysis.

Junginger, Tobias / Payraudeau, Sylvain / Imfeld, Gwenaël

Chemosphere

2022 Volume 305, Page(s) 135329

Abstract: Terbutryn is a widely used biocide in construction materials like paint and render to prevent the growth of microorganisms, algae and fungi. Terbutryn is released from the facades into the environment during rainfall, contaminating surface waters, soil ... ...

Abstract	Terbutryn is a widely used biocide in construction materials like paint and render to prevent the growth of microorganisms, algae and fungi. Terbutryn is released from the facades into the environment during rainfall, contaminating surface waters, soil and groundwater. Knowledge of terbutryn dissipation from the facades to aquatic ecosystems is scarce. Here, we examined in laboratory microcosms degradation half-lives, formation of transformation products and carbon and nitrogen isotope fractionation during terbutryn direct (UV light with λ = 254 nm and simulated sunlight) and indirect (simulated sunlight with nitrate) photodegradation, abiotic hydrolysis (pH = 1, 7 and 13), and aerobic biodegradation (stormwater pond sediment, soil and activated sludge). Biodegradation half-lives of terbutryn were high (>80 d). Photodegradation under simulated sunlight and hydrolysis at extreme pH values indicated slow degradability and accumulation in the environment. Photodegradation resulted in a variety of transformation products, whereas abiotic hydrolysis lead solely to terbutryn-2-hydroxy in acidic and basic conditions. Biodegradation indicates degradation to terbutryn-2-hydroxy through terbutryn-sulfoxide. Compound-specific isotope analysis (CSIA) of terbutryn holds potential to differentiate degradation pathways. Carbon isotope fractionation values (ε
MeSH term(s)	Biodegradation, Environmental ; Carbon Isotopes/analysis ; Chemical Fractionation/methods ; Disinfectants ; Ecosystem ; Hydrolysis ; Nitrates ; Nitrogen Isotopes/analysis ; Organic Chemicals ; Photolysis ; Soil ; Triazines
Chemical Substances	Carbon Isotopes ; Disinfectants ; Nitrates ; Nitrogen Isotopes ; Organic Chemicals ; Soil ; Triazines ; terbutryne (ZXL474TLFP)
Language	English
Publishing date	2022-06-13
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2022.135329
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Zs.A 2540: Show issues

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Article ; Online: A diagnostic performance study of the 2022 American College of Rheumatology/EULAR classification criteria for giant cell arteritis in a cohort of patients presenting with suspected giant cell arteritis.

Hemmig, Andrea K / Aschwanden, Markus / Imfeld, Stephan / Berger, Christoph T / Daikeler, Thomas

Arthritis & rheumatology (Hoboken, N.J.)

2023 Volume 75, Issue 6, Page(s) 1075–1077

MeSH term(s)	Humans ; United States ; Giant Cell Arteritis/diagnosis ; Rheumatology ; Temporal Arteries ; Patients
Language	English
Publishing date	2023-03-28
Publishing country	United States
Document type	Letter ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	2756371-6
ISSN	2326-5205 ; 2326-5191
ISSN (online)	2326-5205
ISSN	2326-5191
DOI	10.1002/art.42440
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Zs.A 24: Show issues

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Article: Who is afraid of Christmas? The effect of Christmas and Easter holidays on psychiatric hospitalizations and emergencies-Systematic review and single center experience from 2012 to 2021.

Schneider, Else / Liwinski, Timur / Imfeld, Lukas / Lang, Undine E / Brühl, Annette B

Frontiers in psychiatry

2023 Volume 13, Page(s) 1049935

Abstract: Background: Major holidays such as Christmas and New Year's Eve are regular occasions for get-togethers in families and other social groups. Socially, these days are often loaded with memories and expectations but also involve the potential for ... ...

Abstract	Background: Major holidays such as Christmas and New Year's Eve are regular occasions for get-togethers in families and other social groups. Socially, these days are often loaded with memories and expectations but also involve the potential for interpersonal tension and conflicts and disappointments. In addition, loneliness might also be most intense during these days. All these factors might lead to the expectation of increased mental distress and subsequently increased help-seeking in psychiatric contexts resulting in emergency psychiatric contacts, psychiatric hospitalizations, and even suicidal behavior. But is there evidence for increased psychiatric emergencies and hospitalizations around the days of Christmas? Methods: The existing evidence is systematically reviewed here (studies in PubMed in English investigating annual and Christmas-related variations in suicide (attempts), psychiatric emergencies and hospitalizations, last search date (13.07.2022) and complemented by an analysis of acute admissions at the University Psychiatry Clinics Basel, Switzerland, around Christmas and Easter holidays compared to the other days of the year. Easter was chosen as a comparison holiday. Results: In 25 reviewed studies, Christmas holidays were not associated with increased utilization of emergency psychiatric services. In contrast, hospitalizations were lower on Christmas and other holidays than the rest of the year. Analyzing the annual variation of 26,088 hospitalizations in our center between 2012 and 2021 revealed the same pattern. Conclusion: The assumption of increased utilization of psychiatric emergency services on Christmas and other major holidays is not confirmed by multiple studies around the globe in various socio-cultural and medical settings. The study is registered in the international prospective register for systematic reviews (PROSPERO; 351057). Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier 351057.
Language	English
Publishing date	2023-01-11
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2022.1049935
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Article ; Conference proceedings: Vergleich postoperativer Schmerz-Scores bei Hunden mit totalem Hüftgelenksersatz (THR) unter Infusion von Lidocain-Ketamin oder epiduralem Morphin-Methadon

Imfeld, T / Steblaj, BB

Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere

2020 Volume 48, Issue 05

Event/congress	5. Tagung der DVG-Fachgruppe Veterinärmedizinische Anästhesie, Intensivmedizin, Notfallmedizin & Schmerztherapie (VAINS), Berlin, 2020-10-16
Language	German
Publishing date	2020-10-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ISSN	2567-5842 ; 1434-1239
ISSN (online)	2567-5842
ISSN	1434-1239
DOI	10.1055/s-0040-1716617
Database	Thieme publisher's database

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Article ; Online: Pre-hospital transfusion of post-traumatic hemorrhage: Medical and regulatory aspects.

Labarthe, A / Mennecart, T / Imfeld, C / Lély, P / Ausset, S

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine

2021 Volume 28, Issue 4, Page(s) 391–396

Abstract: Data of good methodological quality have recently become available to support prehospital use of transfusion in the severe trauma setting. Consistent with recent guidelines for the implementation of damage control resuscitation in the hospital in this ... ...

Abstract	Data of good methodological quality have recently become available to support prehospital use of transfusion in the severe trauma setting. Consistent with recent guidelines for the implementation of damage control resuscitation in the hospital in this setting and in the wake of numerous cohort study data from wartime medicine, they are now guided by recent guidelines for the use of freeze-dried plasma. The main difficulties to overcome in order to implement a practice are of a regulatory and logistic nature.
MeSH term(s)	Cohort Studies ; Emergency Medical Services ; Hemorrhage/etiology ; Hemorrhage/therapy ; Hospitals ; Humans ; Resuscitation ; Wounds and Injuries/complications ; Wounds and Injuries/therapy
Language	English
Publishing date	2021-08-28
Publishing country	France
Document type	Journal Article
ZDB-ID	1204698-x
ISSN	1953-8022 ; 1246-7820
ISSN (online)	1953-8022
ISSN	1246-7820
DOI	10.1016/j.tracli.2021.08.345
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Zs.A 4097: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 308: Show issues

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Article ; Online: Prior polymyalgia rheumatica is associated with sonographic vasculitic changes in newly diagnosed patients with giant cell arteritis.

Hemmig, Andrea K / Aschwanden, Markus / Berger, Christoph T / Kyburz, Diego / Mensch, Noemi / Staub, Daniel / Stegert, Mihaela / Imfeld, Stephan / Daikeler, Thomas

Rheumatology (Oxford, England)

2023

Abstract: Objectives: To investigate the hypothesis that a history of polymyalgia rheumatica (PMR) is associated with a more severe and damaging disease course in newly diagnosed giant cell arteritis (GCA) patients.: Methods: Retrospective analysis of GCA ... ...

Abstract	Objectives: To investigate the hypothesis that a history of polymyalgia rheumatica (PMR) is associated with a more severe and damaging disease course in newly diagnosed giant cell arteritis (GCA) patients. Methods: Retrospective analysis of GCA patients diagnosed between 12/2006 and 05/2021. We compared vascular ultrasound findings (presence of vasculitis and vascular stenosis) in GCA patients with and without prior PMR. Results: 49 of 311 GCA patients (15.8%) had prior PMR in median 30.6 (IQR 7.1-67.3) months before GCA diagnosis. Patients with prior PMR had more often large vessel vasculitis (LVV) (51.0% vs 25.0%, p< 0.001) and stenosis within the vasculitic segments (18.4% vs 3.1%, p< 0.001) on ultrasound. In multivariable analysis, prior PMR remained significantly associated with LVV (OR 7.65, 95% CI 2.72-23.97, p< 0.001). Polymyalgic symptoms at GCA diagnosis in the patients without prior PMR were not associated with a higher prevalence of LVV (p= 0.156). Conclusion: Patients with a diagnosis of PMR before GCA diagnosis had two times more often large vessel involvement and significant more vasculitic stenoses on ultrasound examination than patients without prior PMR. Pre-existing PMR is an independent risk factor for more extensive and advanced ultrasound findings at GCA diagnosis. The contribution of subclinical vasculitis to disease associated damage has to be further studied.
Language	English
Publishing date	2023-08-30
Publishing country	England
Document type	Journal Article
ZDB-ID	1464822-2
ISSN	1462-0332 ; 1462-0324
ISSN (online)	1462-0332
ISSN	1462-0324
DOI	10.1093/rheumatology/kead450
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Zs.B 240: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 497: Show issues

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Article: Ernährung und Zahnkaries. Nicht kariogene Zwischenmahlzeiten und Süssigkeiten: Marktnische für kleine und mittlere Unternehmen der Nahrungsmittelindustrie. Gespräch mit Dr. med. dent. T. Imfeld.

Imfeld, T

Swiss dent

1983 Volume 4, Issue 9, Page(s) 6–10

Title translation	Nutrition and dental caries. Non-cariogenic between-meal snacks and sweets: a marketplace for small and average-size businesses in the food industry. An interview with Dr. med. dent. T. Imfeld.
MeSH term(s)	Dental Caries/prevention & control ; Eating ; Feeding Behavior ; Food ; Food-Processing Industry ; Humans ; Nutritional Physiological Phenomena
Language	German
Publishing date	1983-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	604660-5
ISSN	0251-1657
ISSN	0251-1657
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Zs.B 2531: Show issues

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Article ; Online: Imaging to predict early relapses after treatment discontinuation in patients with large vessel giant cell arteritis - A cohort study.

Hemmig, Andrea K / Rottenburger, Christof / Baruti, Luan / Mensch, Noemi / Aschwanden, Markus / Kyburz, Diego / Pradella, Maurice / Staub, Daniel / Stegert, Mihaela / Berger, Christoph T / Imfeld, Stephan / Sommer, Gregor / Daikeler, Thomas

Seminars in arthritis and rheumatism

2024 Volume 66, Page(s) 152425

Abstract: Objectives: To investigate the value of [: Methods: This study included patients with LV-GCA whose treatment was discontinued between 2018 and 2023. All patients underwent PET/CT and/or MRI at the time of treatment discontinuation in clinical ... ...

Abstract	Objectives: To investigate the value of [ Methods: This study included patients with LV-GCA whose treatment was discontinued between 2018 and 2023. All patients underwent PET/CT and/or MRI at the time of treatment discontinuation in clinical remission. Qualitative and quantitative PET/CT scores, by measuring standardized uptake values (SUV), and semiquantitative MRI scores of the aorta and supraaortic vessels were compared between patients who relapsed within 4 months after treatment discontinuation and those who did not. Results: Forty patients were included (median age 67.4 years, interquartile range (IQR) 60.8-74.0; 77.5 % females). Eleven patients (27.5 %) relapsed after treatment discontinuation (time to relapse 1.9 months, IQR 1.4-3.3). Patients who relapsed were comparable to those who remained in remission with respect to the presence of active vasculitis on MRI and/or PET/CT (54.5% vs. 58.6 %, p = 1.0), the number of segments with vasculitic findings on MRI (0, IQR 0.0-1.5, vs. 2, IQR 0.0-3.0, p = 0.221) or the highest SUV artery/liver ratio on PET/CT (1.5, IQR 1.4-1.6, vs. 1.3, IQR 1.2-1.6, p = 0.505). The median number of vasculitic segments on PET/CT was 2.5 (IQR 0.5-4.5) in those with vs. 0 (IQR 0.0-1.5, p = 0.085) in those without relapse, and the PET/CT scores 4.5 (IQR 0.75-8.25) vs. 0 (IQR 0.0-3.0, p = 0.172). Conclusion: PET/CT or MRI at treatment stop did not predict relapse and may not be suited to guide treatment decisions in patients with LV-GCA in remission.
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	120247-9
ISSN	1532-866X ; 0049-0172
ISSN (online)	1532-866X
ISSN	0049-0172
DOI	10.1016/j.semarthrit.2024.152425
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