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  1. Article ; Online: Biomedical, socio-behavioral, and implementation science gaps in multipurpose prevention technology research.

    Cummins, James E / Allen, C Leigh / Lee, Sonia / Senn, Theresa E

    Frontiers in reproductive health

    2023  Volume 5, Page(s) 1244659

    Abstract: There is strong global need for the development of Multipurpose Prevention Technologies (MPTs) that prevent HIV, pregnancy, and/or other sexually transmitted infections (STIs). However, despite decades of research focused on the development of MPTs, ... ...

    Abstract There is strong global need for the development of Multipurpose Prevention Technologies (MPTs) that prevent HIV, pregnancy, and/or other sexually transmitted infections (STIs). However, despite decades of research focused on the development of MPTs, numerous research gaps remain, contributing to reproductive health disparities. This commentary will highlight biomedical, socio-behavioral, and implementation science gaps in MPT research. Biomedical gaps and barriers include limited dosage forms, challenges around drug selection and stable coformulation of multiple drugs, and an unclear regulatory pathway. Behavioral, social, and structural gaps include lack of research around MPT preferences for some subgroups of potential end users, lack of knowledge around whether MPTs improve uptake, adherence, and persistence vs. separate products, and a need to further understand how social and cultural factors might impact MPT interest and use. Gaps in implementation science research will need to be addressed to better understand how to implement MPTs to maximize effectiveness and benefit. This commentary will also identify opportunities for integrating biomedical and behavioral science around MPTs.
    Language English
    Publishing date 2023-09-01
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-3153
    ISSN (online) 2673-3153
    DOI 10.3389/frph.2023.1244659
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Incorporating a trauma-informed perspective in HIV-related research with transgender and gender diverse individuals.

    Allison, Susannah M / Parker, Karen L / Senn, Theresa E

    Journal of the International AIDS Society

    2022  Volume 25 Suppl 5, Page(s) e25976

    MeSH term(s) Gender Identity ; HIV Infections/epidemiology ; HIV Infections/psychology ; Health Behavior ; Humans ; Social Stigma ; Transgender Persons ; Violence
    Language English
    Publishing date 2022-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2467110-1
    ISSN 1758-2652 ; 1758-2652
    ISSN (online) 1758-2652
    ISSN 1758-2652
    DOI 10.1002/jia2.25976
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  3. Article ; Online: Global mental health and HIV care: gaps and research priorities.

    Senn, Theresa E / Greenwood, Gregory L / Rao, Vasudev R

    Journal of the International AIDS Society

    2021  Volume 24 Suppl 2, Page(s) e25714

    MeSH term(s) Global Health ; HIV Infections/diagnosis ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Health Priorities ; Humans ; Mental Health ; Research
    Language English
    Publishing date 2021-08-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2467110-1
    ISSN 1758-2652 ; 1758-2652
    ISSN (online) 1758-2652
    ISSN 1758-2652
    DOI 10.1002/jia2.25714
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  4. Article ; Online: Advancing long-acting and extended delivery HIV prevention and treatment regimens through behavioural science: NIH workshop directions.

    Morton, Tia / Chege, Wairimu / Swann, Edith / Senn, Theresa E / Cleland, Naana / Renzullo, Philip O / Stirratt, Michael J

    AIDS (London, England)

    2021  Volume 35, Issue 8, Page(s) 1313–1317

    MeSH term(s) Acquired Immunodeficiency Syndrome ; Anti-HIV Agents/therapeutic use ; Behavioral Sciences ; HIV Infections/drug therapy ; HIV Infections/prevention & control ; Humans
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2021-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000002863
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    Zs.A 2228: Show issues Location:
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  5. Article ; Online: Factors related to life satisfaction among urban African American adults receiving care at a publicly-funded sexual health clinic.

    Dunne, Eugene M / Senn, Theresa E / Carey, Kate B / Carey, Michael P

    Psychology, health & medicine

    2017  Volume 23, Issue 3, Page(s) 360–368

    Abstract: Life satisfaction is linked to premature morbidity and mortality and it may be compromised for individuals living in economically-disadvantaged, urban neighborhoods. The present study explores how behavioral and social-environmental health factors are ... ...

    Abstract Life satisfaction is linked to premature morbidity and mortality and it may be compromised for individuals living in economically-disadvantaged, urban neighborhoods. The present study explores how behavioral and social-environmental health factors are associated with life satisfaction among a sample of African American young adults. Participants (N = 307, M
    MeSH term(s) Adolescent ; Adult ; African Americans/psychology ; Anxiety Disorders/psychology ; Depressive Disorder/psychology ; Health Behavior ; Humans ; Male ; Personal Satisfaction ; Quality of Life/psychology ; Reproductive Health Services ; Social Support ; Substance-Related Disorders/psychology ; Urban Population ; Young Adult
    Language English
    Publishing date 2017-08-04
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
    ZDB-ID 1477841-5
    ISSN 1465-3966 ; 1354-8506
    ISSN (online) 1465-3966
    ISSN 1354-8506
    DOI 10.1080/13548506.2017.1362109
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  6. Article: Development and Refinement of a Targeted Sexual Risk Reduction Intervention for Women With a History of Childhood Sexual Abuse.

    Senn, Theresa E / Braksmajer, Amy / Hutchins, Heidi / Carey, Michael P

    Cognitive and behavioral practice

    2017  Volume 24, Issue 4, Page(s) 496–507

    Abstract: Childhood sexual abuse (CSA) is associated with sexual risk behavior in adulthood. Traditional sexual risk reduction interventions do not meet the unique needs of women who have been sexually abused. In the current paper, we describe the four-stage ... ...

    Abstract Childhood sexual abuse (CSA) is associated with sexual risk behavior in adulthood. Traditional sexual risk reduction interventions do not meet the unique needs of women who have been sexually abused. In the current paper, we describe the four-stage process we followed to develop and refine a targeted sexual risk reduction intervention for this population. First, initial quantitative work revealed that the intervention should address how maladaptive thoughts related to traumatic sexualization, trust, powerlessness, and guilt/shame (traumagenic dynamics constructs) influence current sexual behavior. Second, qualitative interviews with 10 women who reported a history of CSA (
    Language English
    Publishing date 2017-01-12
    Publishing country United States
    Document type Journal Article
    ISSN 1077-7229
    ISSN 1077-7229
    DOI 10.1016/j.cbpra.2016.12.001
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  7. Article ; Online: Mediators of the Relation Between Community Violence and Sexual Risk Behavior Among Adults Attending a Public Sexually Transmitted Infection Clinic.

    Senn, Theresa E / Walsh, Jennifer L / Carey, Michael P

    Archives of sexual behavior

    2016  Volume 45, Issue 5, Page(s) 1069–1082

    Abstract: ... about the relation between community violence (i.e., violence that is witnessed or experienced in one's neighborhood ... i.e., mental health, substance use, and experiencing intimate partner violence). A separate sample ...

    Abstract Prior research shows that violence is associated with sexual risk behavior, but little is known about the relation between community violence (i.e., violence that is witnessed or experienced in one's neighborhood) and sexual risk behavior. To better understand contextual influences on HIV risk behavior, we asked 508 adult patients attending a publicly funded STI clinic in the U.S. (54 % male, M age = 27.93, 68 % African American) who were participating in a larger trial to complete a survey assessing exposure to community violence, sexual risk behavior, and potential mediators of the community violence-sexual risk behavior relation (i.e., mental health, substance use, and experiencing intimate partner violence). A separate sample of participants from the same trial completed measures of sexual behavior norms, which were aggregated to create measures of census tract sexual behavior norms. Data analyses controlling for socioeconomic status revealed that higher levels of community violence were associated with more sexual partners for men and with more episodes of unprotected sex with non-steady partners for women. For both men and women, substance use and mental health mediated the community violence-sexual risk behavior relation; in addition, for men only, experiencing intimate partner violence also mediated this relation. These results confirm that, for individuals living in communities with high levels of violence, sexual risk reduction interventions need to address intimate partner violence, substance use, and mental health to be optimally effective.
    MeSH term(s) Adult ; Ambulatory Care Facilities ; Female ; Humans ; Intimate Partner Violence/statistics & numerical data ; Male ; Risk-Taking ; Sexual Behavior/statistics & numerical data ; Sexually Transmitted Diseases/epidemiology ; Sexually Transmitted Diseases/prevention & control ; Unsafe Sex/statistics & numerical data ; Violence/statistics & numerical data
    Language English
    Publishing date 2016-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 184221-3
    ISSN 1573-2800 ; 0004-0002
    ISSN (online) 1573-2800
    ISSN 0004-0002
    DOI 10.1007/s10508-016-0714-6
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    Zs.A 1106: Show issues Location:
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  8. Article ; Online: The Potential of Pre-Exposure Prophylaxis for Women in Violent Relationships.

    Braksmajer, Amy / Senn, Theresa E / McMahon, James

    AIDS patient care and STDs

    2016  Volume 30, Issue 6, Page(s) 274–281

    Abstract: HIV and intimate partner violence (IPV) are significant intersecting threats to women's health. Women in violent relationships have few feasible HIV risk reduction options as traditional prevention methods are largely dependent on a partner's cooperation. ...

    Abstract HIV and intimate partner violence (IPV) are significant intersecting threats to women's health. Women in violent relationships have few feasible HIV risk reduction options as traditional prevention methods are largely dependent on a partner's cooperation. The purpose of this review is to explore potential benefits and drawbacks of pre-exposure prophylaxis (PrEP) use among women in the United States experiencing IPV. Advantages of PrEP use in this population include the potential for covert or autonomous use, coital independence, dual protection against sexual and injection risk, and facilitated connections to social services. A number of barriers, however, may interfere with the effective use of PrEP, including partner resistance, cost, frequent medical visits, gendered norms regarding sexuality, and stigma. To realize its potential for women in violent relationships, it will be necessary to incorporate PrEP into behavioral and structural interventions that encourage uptake, facilitate adherence, ensure women's safety, and challenge existing gender norms.
    MeSH term(s) Adult ; Anti-HIV Agents/therapeutic use ; Female ; Gender Identity ; HIV Infections/prevention & control ; Humans ; Interpersonal Relations ; Intimate Partner Violence ; Pre-Exposure Prophylaxis ; Risk Reduction Behavior ; Sexual Behavior ; Sexual Partners ; Social Stigma ; Spouse Abuse ; United States
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2016-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1326868-5
    ISSN 1557-7449 ; 0893-5068 ; 1087-2914
    ISSN (online) 1557-7449
    ISSN 0893-5068 ; 1087-2914
    DOI 10.1089/apc.2016.0098
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    Zs.A 2328: Show issues Location:
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  9. Article ; Online: Health and life concerns among patients attending a publicly funded sexually transmitted infection clinic.

    Carey, Michael P / Senn, Theresa E

    Journal of public health management and practice : JPHMP

    2013  Volume 19, Issue 1, Page(s) E30–4

    Abstract: Objectives: Sexually transmitted infection (STI) clinics provide opportune settings in which to address a range of health concerns with an underserved population. The current research sought to identify and prioritize patients' health and social ... ...

    Abstract Objectives: Sexually transmitted infection (STI) clinics provide opportune settings in which to address a range of health concerns with an underserved population. The current research sought to identify and prioritize patients' health and social concerns.
    Design and setting: Patients attending a publicly funded STI clinic (50% female, 62% African American) were invited to participate in a cross-sectional study. Participants completed a brief paper-and-pencil questionnaire.
    Participants: Participants were 150 patients attending the STI clinic.
    Main outcome measure: A survey of health and social concerns.
    Results: Participants rated STIs, human immunodeficiency virus/AIDS, teeth problems, and eye problems as their most concerning health problems. Other than STI-related concerns, patients expressed few concerns about their somatic health. Instead, these (mostly younger) patients expressed more concern about economic issues.
    Conclusions: Sexually transmitted infection clinics provide a unique setting to provide health and mental health services to an at-need, underserved population; however, patients may prefer assistance with economic issues.
    MeSH term(s) Adult ; Ambulatory Care Facilities/statistics & numerical data ; Cross-Sectional Studies ; Female ; Health Status ; Humans ; Male ; Mental Health ; Public Sector ; Sexually Transmitted Diseases/epidemiology ; Sexually Transmitted Diseases/psychology ; Socioeconomic Factors
    Language English
    Publishing date 2013-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2027860-3
    ISSN 1550-5022 ; 1078-4659
    ISSN (online) 1550-5022
    ISSN 1078-4659
    DOI 10.1097/PHH.0b013e31822d4bd5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5302: Show issues Location:
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  10. Article: Positive social interaction offsets impact of low socioeconomic status on stress.

    Woodward, Eva N / Walsh, Jennifer L / Senn, Theresa E / Carey, Michael P

    Journal of the National Medical Association

    2017  Volume 110, Issue 4, Page(s) 371–377

    Abstract: Background: Stress is associated with unhealthy behaviors and premature morbidity and mortality, especially among those of low socioeconomic status (SES). Clarifying the roles of stress-related risk and protective factors can guide interventions ... ...

    Abstract Background: Stress is associated with unhealthy behaviors and premature morbidity and mortality, especially among those of low socioeconomic status (SES). Clarifying the roles of stress-related risk and protective factors can guide interventions designed to reduce stress and improve health among socioeconomically disadvantaged populations.
    Purpose: (1) Replicate prior research showing that lower SES is associated with higher stress in a predominantly racial minority, socioeconomically disadvantaged sample, and (2) test the hypothesis that different types of social support (a protective factor) mitigate the deleterious effects of SES on self-reported perceived stress.
    Methods: Low-income patients (N = 508, 54% male, 68% African American, M
    Results: Individuals of lower SES, β = -0.27 (0.08), p < 0.01, and lower overall social support, β = -0.47 (0.05), p < 0.001, reported higher stress. Social support moderated associations between SES and stress, with participants with lower SES benefitting the most from social support. Of the four types of social support that were measured, positive social interaction was the strongest moderator, β = 0.20 (0.08), p = 0.01.
    Conclusions: The associations among SES, stress, and social support corroborate prior research. Positive social interaction was particularly important for decreasing stress among socioeconomically disadvantaged persons.
    MeSH term(s) Adolescent ; Adult ; African Americans/psychology ; Female ; Health Surveys ; Humans ; Male ; Middle Aged ; Models, Psychological ; Poverty/psychology ; Social Class ; Social Support ; Stress, Psychological/economics ; Stress, Psychological/psychology ; United States ; Young Adult
    Language English
    Publishing date 2017-08-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 419737-9
    ISSN 0027-9684
    ISSN 0027-9684
    DOI 10.1016/j.jnma.2017.07.006
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    Zs.B 150: Show issues Location:
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