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  1. Article: Left lower lobe sleeve resection for the clear cell variant of pulmonary mucoepidermoid carcinoma: A case report.

    Yu, Xiao-Hui / Wang, Wen-Xiang / Yang, De-Song / Gong, Liang-Hui

    World journal of clinical cases

    2024  Volume 12, Issue 8, Page(s) 1422–1429

    Abstract: Background: Pulmonary mucoepidermoid carcinoma (PMEC) is a rare malignancy that arises from minor salivary glands within the tracheobronchial tree. The clear cell variant of PMEC is exceptionally uncommon and presents notable diagnostic challenges, ... ...

    Abstract Background: Pulmonary mucoepidermoid carcinoma (PMEC) is a rare malignancy that arises from minor salivary glands within the tracheobronchial tree. The clear cell variant of PMEC is exceptionally uncommon and presents notable diagnostic challenges, primarily attributable to its morphological similarity to other tumors containing clear cells.
    Case summary: A 22-year-old male, formerly in good health, came in with a two-month duration of persistent cough and production of sputum. Subsequent imaging and bronchoscopy examinations revealed a 2 cm tumor in the distal left main bronchus, which resulted in complete atelectasis of the left lung. Further assessment
    Conclusion: This article describes an unusual case of a clear cell variant of PMEC characterized by the presence of a
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v12.i8.1422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Harzianic acids and oxazolidinone from the endophytic fungus Ilyonectria sp. and their cytotoxicity activity.

    Tong, Shun-Yao / Ye, Ke / Wang, Wen-Xiang / Ai, Hong-Lian

    Fitoterapia

    2024  Volume 175, Page(s) 105941

    Abstract: Four undescribed compounds including three harzianic acids (1, 3 and 4) and one oxazolidinone (2), along with three known ones (5-7) were isolated from the solid fermented product of endophytic fungus Ilyonectria sp., their structures were elucidated as ... ...

    Abstract Four undescribed compounds including three harzianic acids (1, 3 and 4) and one oxazolidinone (2), along with three known ones (5-7) were isolated from the solid fermented product of endophytic fungus Ilyonectria sp., their structures were elucidated as 1-amino-harzianic acid (1), ilyonectria-oxazolidinone (2),10'-nor- isoharzianic acid (3), isohomoharzianic acid (4), harzianic acid (5), isoharzianic acid (6), homoharzianic acid (7) by means of detailed chemical evidences and spectroscopic data analysis. All the compounds were evaluated for cytotoxicity against SMMC-7721 human cancer cell lines by MTS assay. Among the seven tested compounds, 1-amino-harzianic acid (1) demonstrated well cytotoxic activity against SMMC-7721 with IC
    Language English
    Publishing date 2024-04-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 412385-2
    ISSN 1873-6971 ; 0367-326X
    ISSN (online) 1873-6971
    ISSN 0367-326X
    DOI 10.1016/j.fitote.2024.105941
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1873: Show issues Location:
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  3. Article ; Online: Isolation and identification of novel phenolic and lignan glycosides from

    Feng, Xin / Yang, Ce / Wang, Wen-Xiang / Wang, Ju-Tao

    Journal of Asian natural products research

    2023  Volume 25, Issue 10, Page(s) 992–998

    Abstract: Phytochemical analyses ... ...

    Abstract Phytochemical analyses of
    MeSH term(s) Lignans/pharmacology ; Swertia/chemistry ; Glycosides/pharmacology ; Glycosides/chemistry ; Plant Extracts/chemistry ; Magnetic Resonance Spectroscopy ; Phenols/pharmacology ; Phenols/chemistry
    Chemical Substances Lignans ; Glycosides ; Plant Extracts ; Phenols
    Language English
    Publishing date 2023-03-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077926-4
    ISSN 1477-2213 ; 1028-6020
    ISSN (online) 1477-2213
    ISSN 1028-6020
    DOI 10.1080/10286020.2023.2190520
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  4. Article ; Online: Sex-specific gene expression patterns in head and neck squamous cell carcinomas

    Shuo Wang / Wei Pan / Wen-xiang Mi / Shao-hai Wang

    Heliyon, Vol 9, Iss 4, Pp e14890- (2023)

    2023  

    Abstract: Objective: The head and neck squamous cell carcinomas (HNSCCs) have higher incidence rates in men, but the reasons are still obscure. This study aimed to investigate the sex-specific gene expression patterns and predict the regulatory mechanisms. Design: ...

    Abstract Objective: The head and neck squamous cell carcinomas (HNSCCs) have higher incidence rates in men, but the reasons are still obscure. This study aimed to investigate the sex-specific gene expression patterns and predict the regulatory mechanisms. Design: Data including clinical, survival, RNA-seq, miRNA, and methylation information were derived from The Cancer Genome Atlas (TCGA). A total of 131 paired male and female cases were included based on propensity score matching. We concentrated on the prognostic values of the sex-specific pathways enriched by differentially expressed genes (DEGs) and predicted the potential regulatory mechanisms from immune cell infiltration, ceRNA regulatory network, methylation, and differential coexpression analysis. Results: Compared with females, males exhibited a lower activity of immune-related functions and higher activities of mitochondrial and ubiquitination functions. The pathway activities were associated with the prognosis of males but less relevant to females. We extracted eight pathways with sex-biased survival patterns, of which five were about down-regulated immune functions, and three were up-regulated pathways (GTP biosynthetic, DNA polymerase, and spliceosomal complex assembly). The five immune pathways were moderately or strongly correlated with the proportion of macrophages. We identified six over-expressed lncRNAs that might be involved in the regulation of the three up-regulated pathways. These lncRNAs exhibited a lower methylation density in males, which might account for their over-expression. Conclusions: For HNSCCs, males were characterized by immunosuppression. It was a sign of unfavorable prognosis and might be associated the proportion of macrophages. LncRNAs and methylation might be involved in the regulation of these pathways.
    Keywords HNSCCs ; Sexes ; Immunosuppression ; LncRNAs ; Spliceosome ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 570
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Design and experiment of high-field asymmetric waveform ion mobility spectrometry chip based on an integrated temperature control printed circuit board structure.

    Zeng, Hao / Zhang, Yu-Qiao / Wang, Yi-Fei / Du, Xiao-Xia / Xiao, Wen-Xiang / Li, Hua

    Rapid communications in mass spectrometry : RCM

    2024  Volume 38, Issue 5, Page(s) e9699

    Abstract: Rationale: During the detection of volatile organic compounds (VOC) using high-field asymmetric waveform ion mobility spectrometry (FAIMS), the ambient temperature significantly impacts the accuracy of planar FAIMS. To mitigate the influence of ambient ... ...

    Abstract Rationale: During the detection of volatile organic compounds (VOC) using high-field asymmetric waveform ion mobility spectrometry (FAIMS), the ambient temperature significantly impacts the accuracy of planar FAIMS. To mitigate the influence of ambient temperature on detection accuracy and enhance resolution, a FAIMS system based on the inner impedance characteristics of a printed circuit board (PCB) was designed for temperature control.
    Methods: This study, conducted under standard atmospheric pressure, aimed to assess the signal stability of a planar FAIMS instrument with and without temperature control, and the effect of temperature change on the detection ability of acetone, ethanol, and their mixture was studied using PCB self-heating.
    Results: Experimental results demonstrated that the base noise in FAIMS with temperature control was 0.2 pA, whereas that in FAIMS without temperature control was 1.8 pA. Notably, with increasing temperature, the detection ability of FAIMS changes accordingly. The optimal relative detection ability of acetone was observed when the electrode plate was heated to 45°C under an electric field of 15 kV/cm.
    Conclusions: This study provides a novel approach to improve the resolving power of FAIMS systems and their signal-to-noise ratio. The utilization of a PCB-based temperature control proved effective in stabilizing FAIMS signal characteristics and optimizing detection capabilities, particularly for VOCs such as acetone. These findings have significant implications for improving the accuracy and resolving power of FAIMS systems in VOC detection applications.
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 58731-x
    ISSN 1097-0231 ; 0951-4198
    ISSN (online) 1097-0231
    ISSN 0951-4198
    DOI 10.1002/rcm.9699
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3461: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article: Sex-specific gene expression patterns in head and neck squamous cell carcinomas.

    Wang, Shuo / Pan, Wei / Mi, Wen-Xiang / Wang, Shao-Hai

    Heliyon

    2023  Volume 9, Issue 4, Page(s) e14890

    Abstract: Objective: The head and neck squamous cell carcinomas (HNSCCs) have higher incidence rates in men, but the reasons are still obscure. This study aimed to investigate the sex-specific gene expression patterns and predict the regulatory mechanisms.: ... ...

    Abstract Objective: The head and neck squamous cell carcinomas (HNSCCs) have higher incidence rates in men, but the reasons are still obscure. This study aimed to investigate the sex-specific gene expression patterns and predict the regulatory mechanisms.
    Design: Data including clinical, survival, RNA-seq, miRNA, and methylation information were derived from The Cancer Genome Atlas (TCGA). A total of 131 paired male and female cases were included based on propensity score matching. We concentrated on the prognostic values of the sex-specific pathways enriched by differentially expressed genes (DEGs) and predicted the potential regulatory mechanisms from immune cell infiltration, ceRNA regulatory network, methylation, and differential coexpression analysis.
    Results: Compared with females, males exhibited a lower activity of immune-related functions and higher activities of mitochondrial and ubiquitination functions. The pathway activities were associated with the prognosis of males but less relevant to females. We extracted eight pathways with sex-biased survival patterns, of which five were about down-regulated immune functions, and three were up-regulated pathways (GTP biosynthetic, DNA polymerase, and spliceosomal complex assembly). The five immune pathways were moderately or strongly correlated with the proportion of macrophages. We identified six over-expressed lncRNAs that might be involved in the regulation of the three up-regulated pathways. These lncRNAs exhibited a lower methylation density in males, which might account for their over-expression.
    Conclusions: For HNSCCs, males were characterized by immunosuppression. It was a sign of unfavorable prognosis and might be associated the proportion of macrophages. LncRNAs and methylation might be involved in the regulation of these pathways.
    Language English
    Publishing date 2023-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e14890
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  7. Article ; Online: Relationship Between Short-chain Fatty Acids and Parkinson's Disease: A Review from Pathology to Clinic.

    Duan, Wen-Xiang / Wang, Fen / Liu, Jun-Yi / Liu, Chun-Feng

    Neuroscience bulletin

    2023  Volume 40, Issue 4, Page(s) 500–516

    Abstract: Parkinson's disease (PD) is a complicated neurodegenerative disease, characterized by the accumulation of α-synuclein (α-syn) in Lewy bodies and neurites, and massive loss of midbrain dopamine neurons. Increasing evidence suggests that gut microbiota and ...

    Abstract Parkinson's disease (PD) is a complicated neurodegenerative disease, characterized by the accumulation of α-synuclein (α-syn) in Lewy bodies and neurites, and massive loss of midbrain dopamine neurons. Increasing evidence suggests that gut microbiota and microbial metabolites are involved in the development of PD. Among these, short-chain fatty acids (SCFAs), the most abundant microbial metabolites, have been proven to play a key role in brain-gut communication. In this review, we analyze the role of SCFAs in the pathology of PD from multiple dimensions and summarize the alterations of SCFAs in PD patients as well as their correlation with motor and non-motor symptoms. Future research should focus on further elucidating the role of SCFAs in neuroinflammation, as well as developing novel strategies employing SCFAs and their derivatives to treat PD.
    MeSH term(s) Humans ; Parkinson Disease/metabolism ; Neurodegenerative Diseases/pathology ; Brain/pathology ; Mesencephalon/metabolism ; Fatty Acids, Volatile/metabolism
    Chemical Substances Fatty Acids, Volatile
    Language English
    Publishing date 2023-09-27
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2419741-5
    ISSN 1995-8218 ; 1673-7067
    ISSN (online) 1995-8218
    ISSN 1673-7067
    DOI 10.1007/s12264-023-01123-9
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    Zs.A 6734: Show issues Location:
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  8. Article ; Online: Correction: Geography, phylogeny and host switch drive the coevolution of parasitic Gyrodactylus flatworms and their hosts.

    Lei, Hong-Peng / Jakovlić, Ivan / Zhou, Shun / Liu, Xiang / Yan, Chuan / Jin, Xiao / Wang, Bo / Li, Wen-Xiang / Wang, Gui-Tang / Zhang, Dong

    Parasites & vectors

    2024  Volume 17, Issue 1, Page(s) 125

    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2409480-8
    ISSN 1756-3305 ; 1756-3305
    ISSN (online) 1756-3305
    ISSN 1756-3305
    DOI 10.1186/s13071-024-06223-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Zhong gu wen xue si xiang

    Wang, Yao

    (Zhong gu wen xue shi lun zhi yi ; Zhong guo gu dian wen xue yan jiu cong kan ; 中古文學史論之一 ; 中国古典文学研究叢刊)

    1953  

    Author's details Wang yao
    Series title Zhong gu wen xue shi lun zhi yi
    Zhong guo gu dian wen xue yan jiu cong kan
    中古文學史論之一
    中国古典文学研究叢刊
    Language Chinese
    Size 1, 3, 194 S
    Edition Liu ban
    Publisher Tang di chu ban she
    Publishing place Shang hai
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  10. Article ; Online: Isolation and identification of novel phenolic and lignan glycosides from Swertia davidii Franch

    Feng, Xin / Yang, Ce / Wang, Wen-Xiang / Wang, Ju-Tao

    Journal of Asian Natural Products Research. 2023 Oct. 3, v. 25, no. 10 p.992-998

    2023  

    Abstract: Phytochemical analyses of Swertia davidii Franch. extracts using column chromatography and semi-preparative HPLC were performed. Two novel phenolic glycosides named swertiosides A and B (compounds 1 and 2, respectively) were isolated and characterized. ... ...

    Abstract Phytochemical analyses of Swertia davidii Franch. extracts using column chromatography and semi-preparative HPLC were performed. Two novel phenolic glycosides named swertiosides A and B (compounds 1 and 2, respectively) were isolated and characterized. Four known phenolic glycosides were also extracted (compounds 3-6). The structural characteristics of these novel compounds were analyzed using 1D, 2D NMR, and HRMS. All six compounds have never been isolated from this particular plant species before this study. Subsequent assessment of bioactive properties suggested that compounds 1 and 2 exhibited moderate levels of cytotoxicity.
    Keywords Swertia ; chromatography ; cytotoxicity ; glycosides ; lignans ; phytochemicals ; research ; Gentianaceae ; Swertia davidii ; phenolic glycosides ; swertioside A ; swertioside B
    Language English
    Dates of publication 2023-1003
    Size p. 992-998.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2077926-4
    ISSN 1477-2213 ; 1028-6020
    ISSN (online) 1477-2213
    ISSN 1028-6020
    DOI 10.1080/10286020.2023.2190520
    Database NAL-Catalogue (AGRICOLA)

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