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  1. Article ; Online: Chloroquine and hydroxychloroquine for COVID-19: A word of caution.

    Annangi, Srinadh

    Respirology (Carlton, Vic.)

    2020  Volume 25, Issue 7, Page(s) 683–684

    MeSH term(s) Betacoronavirus ; COVID-19 ; Chloroquine ; Coronavirus ; Coronavirus Infections ; Humans ; Hydroxychloroquine ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Chemical Substances Hydroxychloroquine (4QWG6N8QKH) ; Chloroquine (886U3H6UFF)
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country Australia
    Document type Journal Article ; Comment
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.13845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chloroquine and hydroxychloroquine for COVID ‐19

    Annangi, Srinadh

    Respirology

    A word of caution

    2020  Volume 25, Issue 7, Page(s) 683–684

    Keywords Pulmonary and Respiratory Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.13845
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Zs.A 4957: Show issues Location:
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  4. Article: Isotretinoin induced small vessel vasculitis: a life-threatening pulmonary-renal syndrome-a case report.

    Annangi, Srinadh / Pasha, Sara

    Annals of translational medicine

    2021  Volume 9, Issue 7, Page(s) 584

    Abstract: Oral isotretinoin is a synthetic analog of vitamin - A, reserved for cases with severe resistant acne. We hereby report a case of drug-induced vasculitis (DV) from isotretinoin exposure leading to life-threatening pulmonary-renal syndrome requiring ... ...

    Abstract Oral isotretinoin is a synthetic analog of vitamin - A, reserved for cases with severe resistant acne. We hereby report a case of drug-induced vasculitis (DV) from isotretinoin exposure leading to life-threatening pulmonary-renal syndrome requiring immunosuppression and plasmapheresis. A previously healthy 21-year-old female receiving oral isotretinoin presented with a 10-day history of worsening myalgias, arthralgias, and abdominal pain. Soon after admission she progressed to severe pulmonary-renal syndrome requiring intubation and renal replacement therapy. Urinalysis revealed >50 dysmorphic RBC with casts and renal ultrasound was unremarkable. Serological testing was only positive for antineutrophil cytoplasmic antibodies (ANCA) at 1:80 with Anti- proteinase 3 (PR3) at 830 AU/mL and Anti-histone Ab at 2.9. As clinical presentation and serology are highly suggestive of ANCA associated DV, plasmapheresis, and rituximab were also initiated along with the continuation of steroids. She clinically improved but remained dialysis dependent and received a live donor renal transplant. The temporal relationship of symptom onset and drug initiation with no other possible identifiable etiologies-DV in our case was attributed to isotretinoin exposure. Though considered safe, oral Isotretinoin in rare instances can cause the life-threatening pulmonary-renal syndrome. Given its widespread use, it is prudent that prescribers should educate patients regarding the possible symptoms of vasculitis and to seek immediate medical attention when warranted. Physicians should also be vigilant of this complication and should act swiftly to avoid uneventful outcomes.
    Language English
    Publishing date 2021-05-13
    Publishing country China
    Document type Case Reports
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm-20-4212
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Endobronchial Band: An Unusual Bronchoscopy Finding.

    Annangi, Srinadh / Maskey, Ashish P

    Journal of bronchology & interventional pulmonology

    2020  Volume 27, Issue 2, Page(s) 147–149

    MeSH term(s) Bronchi/pathology ; Bronchogenic Cyst/pathology ; Bronchoscopy/methods ; Cough/etiology ; Electrocoagulation/methods ; Endoscopic Ultrasound-Guided Fine Needle Aspiration/methods ; Humans ; Incidental Findings ; Lymphadenopathy/diagnostic imaging ; Lymphadenopathy/therapy ; Male ; Mediastinum/pathology ; Middle Aged ; Tomography, X-Ray Computed/methods ; Treatment Outcome
    Language English
    Publishing date 2020-01-22
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2478320-1
    ISSN 1948-8270 ; 1944-6586
    ISSN (online) 1948-8270
    ISSN 1944-6586
    DOI 10.1097/LBR.0000000000000653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4027: Show issues Location:
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  6. Article ; Online: Early integration of palliative care in chronic obstructive pulmonary disease (COPD) is warranted based on symptom burden and quality of life.

    Yarra, Pradeep / Annangi, Srinadh

    Evidence-based nursing

    2020  Volume 24, Issue 4, Page(s) 130

    MeSH term(s) Hospice and Palliative Care Nursing ; Humans ; Palliative Care ; Pulmonary Disease, Chronic Obstructive/therapy ; Quality of Life
    Language English
    Publishing date 2020-10-01
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1425988-6
    ISSN 1468-9618 ; 1367-6539
    ISSN (online) 1468-9618
    ISSN 1367-6539
    DOI 10.1136/ebnurs-2020-103335
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  7. Article ; Online: Clinical Implications of Bronchodilator Testing: Diagnosing and Differentiating COPD and Asthma-COPD Overlap.

    Annangi, Srinadh / Coz-Yataco, Angel O

    Respiratory care

    2022  Volume 67, Issue 4, Page(s) 440–447

    Abstract: Background: Bronchodilation testing is an important component of spirometry testing, and omitting this procedure has potential clinical implications toward diagnosing respiratory diseases. We aimed to estimate the impact of bronchodilator testing in ... ...

    Abstract Background: Bronchodilation testing is an important component of spirometry testing, and omitting this procedure has potential clinical implications toward diagnosing respiratory diseases. We aimed to estimate the impact of bronchodilator testing in accurately diagnosing COPD and differentiating COPD from asthma-COPD overlap (ACO).
    Methods: The National Health and Nutrition Examination Survey data were analyzed from 2007-2012. Airflow limitation was defined by FEV
    Results: We identified 11,763 subjects ≥ 40 y of age eligible for spirometry; 625 of them had a pre-bronchodilator FEV
    Conclusions: Spirometry with bronchodilation is an important element in the accurate diagnosis of ACO and COPD. Spirometry performed without bronchodilator testing may lead to an estimated misclassification of ACO by 7.6% to 19.8% and overdiagnosis of COPD by 39%.
    MeSH term(s) Asthma/drug therapy ; Bronchodilator Agents/therapeutic use ; Forced Expiratory Volume ; Humans ; Nutrition Surveys ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Spirometry ; Vital Capacity
    Chemical Substances Bronchodilator Agents
    Language English
    Publishing date 2022-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.09215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2285: Show issues Location:
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  8. Article ; Online: Bloody Bronchial Cast-Aftermath of Hemoptysis.

    Annangi, Srinadh / Smith, Kevin H

    American journal of respiratory and critical care medicine

    2019  Volume 201, Issue 2, Page(s) 243–244

    MeSH term(s) Airway Obstruction/etiology ; Bronchoscopy ; Female ; Hemoptysis/therapy ; Humans ; Imaging, Three-Dimensional ; Middle Aged ; Suction ; Thrombosis/complications ; Thrombosis/diagnostic imaging ; Thrombosis/pathology
    Language English
    Publishing date 2019-08-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201906-1277IM
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  9. Article ; Online: Curious Case of Unexplained Dyspnea With Malignancy.

    Annangi, Srinadh / Snyder, Daniel / Smith, Kevin

    Chest

    2020  Volume 158, Issue 5, Page(s) e251–e255

    Abstract: Case presentation: A 48-year-old female never smoker with hypothyroidism and no significant prior respiratory complaints presented with 1 month of gradually worsening dyspnea on exertion. She denied any associated fevers, chills, weight loss, chest pain, ...

    Abstract Case presentation: A 48-year-old female never smoker with hypothyroidism and no significant prior respiratory complaints presented with 1 month of gradually worsening dyspnea on exertion. She denied any associated fevers, chills, weight loss, chest pain, productive cough, hemoptysis, or sick contacts. She was recently diagnosed with stage IV triple negative adenocarcinoma of the breast and was yet to receive chemotherapy.
    MeSH term(s) Cardiac Catheterization/methods ; Chest Pain/diagnosis ; Chest Pain/etiology ; Diagnosis, Differential ; Dyspnea/diagnosis ; Dyspnea/etiology ; Female ; Heart Atria/diagnostic imaging ; Heart Atria/pathology ; Humans ; Microvessels/pathology ; Middle Aged ; Neoplastic Cells, Circulating/pathology ; Patient Care Management/methods ; Pulmonary Circulation ; Tomography, X-Ray Computed/methods ; Triple Negative Breast Neoplasms/complications ; Triple Negative Breast Neoplasms/pathology ; Triple Negative Breast Neoplasms/therapy
    Language English
    Publishing date 2020-11-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.03.077
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  10. Article ; Online: Eosinophilia and fractional exhaled nitric oxide levels in chronic obstructive lung disease.

    Annangi, Srinadh / Nutalapati, Snigdha / Sturgill, Jamie / Flenaugh, Eric / Foreman, Marilyn

    Thorax

    2021  Volume 77, Issue 4, Page(s) 351–356

    Abstract: Introduction: COPD is a heterogeneous disorder with varied phenotypes. We aimed to determine the prevalence of asthma history, peripheral eosinophilia and elevated FeNO levels along with the diagnostic utility of peripheral eosinophilia in identifying ... ...

    Abstract Introduction: COPD is a heterogeneous disorder with varied phenotypes. We aimed to determine the prevalence of asthma history, peripheral eosinophilia and elevated FeNO levels along with the diagnostic utility of peripheral eosinophilia in identifying airway eosinophilic inflammation.
    Methods: National Health and Nutrition Examination Survey data were analysed for the study period 2007-2010. Subjects aged ≥40 years with postbronchodilator FEV
    Results: A total of 3 110 617 weighted COPD cases were identified; predominantly male (64.4%) and non-Hispanic whites (86.1%). Among our COPD subjects, 14.6% had a history of doctor diagnosed asthma, highest among females and other race Americans. The overall prevalence of peripheral eosinophilia is 36%, 38.3% among COPD subjects with asthma history, and 35.6% among COPD without asthma history. The overall prevalence of elevated FeNO ≥25 ppb is 14.3%; 28.7% among COPD subjects with asthma history and 13.0% among COPD without asthma history.
    Discussion: The prevalence of FeNO levels ≥25 ppb and peripheral eosinophilia was significantly higher among COPD subjects with asthma compared with COPD without asthma history. Not all COPD subjects with peripheral eosinophilia and elevated FeNO levels have a reported history of asthma. Our study supports clinically phenotyping COPD subjects with eosinophilic inflammation be independent of their asthma history and peripheral eosinophilia can be used as a surrogate marker in resource-limited settings.
    MeSH term(s) Breath Tests ; Eosinophilia/epidemiology ; Eosinophils ; Female ; Fractional Exhaled Nitric Oxide Testing ; Humans ; Male ; Nitric Oxide/analysis ; Nutrition Surveys ; Pulmonary Disease, Chronic Obstructive
    Chemical Substances Nitric Oxide (31C4KY9ESH)
    Language English
    Publishing date 2021-08-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 204353-1
    ISSN 1468-3296 ; 0040-6376
    ISSN (online) 1468-3296
    ISSN 0040-6376
    DOI 10.1136/thoraxjnl-2020-214644
    Database MEDical Literature Analysis and Retrieval System OnLINE

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