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  1. Article ; Online: Artificial intelligence: Is it wizardry, witchcraft, or a helping hand for an equine veterinarian?

    Alexeenko, Vadim / Jeevaratnam, Kamalan

    Equine veterinary journal

    2023  Volume 55, Issue 5, Page(s) 719–722

    MeSH term(s) Animals ; Humans ; Artificial Intelligence ; Horses ; Veterinarians
    Language English
    Publishing date 2023-08-08
    Publishing country United States
    Document type Editorial
    ZDB-ID 41606-x
    ISSN 2042-3306 ; 0425-1644
    ISSN (online) 2042-3306
    ISSN 0425-1644
    DOI 10.1111/evj.13969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The cardiac sodium channel from function to dysfunction.

    Ahmad, Shiraz / Jeevaratnam, Kamalan

    The Journal of physiology

    2023  Volume 601, Issue 5, Page(s) 903–904

    MeSH term(s) Humans ; Heart ; Long QT Syndrome ; Sodium Channels ; NAV1.5 Voltage-Gated Sodium Channel ; Myocytes, Cardiac
    Chemical Substances Sodium Channels ; NAV1.5 Voltage-Gated Sodium Channel
    Language English
    Publishing date 2023-02-21
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP284172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chloroquine and hydroxychloroquine for COVID-19: implications for cardiac safety.

    Jeevaratnam, Kamalan

    European heart journal. Cardiovascular pharmacotherapy

    2020  Volume 6, Issue 4, Page(s) 256–257

    MeSH term(s) Adenosine Monophosphate/analogs & derivatives ; Alanine/analogs & derivatives ; Betacoronavirus ; COVID-19 ; Chloroquine ; Coronavirus ; Coronavirus Infections/drug therapy ; Humans ; Hydroxychloroquine ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Chemical Substances remdesivir (3QKI37EEHE) ; Adenosine Monophosphate (415SHH325A) ; Hydroxychloroquine (4QWG6N8QKH) ; Chloroquine (886U3H6UFF) ; Alanine (OF5P57N2ZX)
    Keywords covid19
    Language English
    Publishing date 2020-03-31
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2808613-2
    ISSN 2055-6845 ; 2055-6837
    ISSN (online) 2055-6845
    ISSN 2055-6837
    DOI 10.1093/ehjcvp/pvaa041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Chloroquine and hydroxychloroquine for COVID-19

    Jeevaratnam, Kamalan

    European Heart Journal - Cardiovascular Pharmacotherapy

    implications for cardiac safety

    2020  Volume 6, Issue 4, Page(s) 256–257

    Keywords covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 2808613-2
    ISSN 2055-6845 ; 2055-6837
    ISSN (online) 2055-6845
    ISSN 2055-6837
    DOI 10.1093/ehjcvp/pvaa041
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Framing Heartaches: The Cardiac ECM and the Effects of Age.

    Ringström, Nathalie / Edling, Charlotte / Nalesso, Giovanna / Jeevaratnam, Kamalan

    International journal of molecular sciences

    2023  Volume 24, Issue 5

    Abstract: The cardiac extracellular matrix (ECM) is involved in several pathological conditions, and age itself is also associated with certain changes in the heart: it gets larger and stiffer, and it develops an increased risk of abnormal intrinsic rhythm. This, ... ...

    Abstract The cardiac extracellular matrix (ECM) is involved in several pathological conditions, and age itself is also associated with certain changes in the heart: it gets larger and stiffer, and it develops an increased risk of abnormal intrinsic rhythm. This, therefore, makes conditions such as atrial arrythmia more common. Many of these changes are directly related to the ECM, yet the proteomic composition of the ECM and how it changes with age is not fully resolved. The limited research progress in this field is mainly due to the intrinsic challenges in unravelling tightly bound cardiac proteomic components and also the time-consuming and costly dependency on animal models. This review aims to give an overview of the composition of the cardiac ECM, how different components aid the function of the healthy heart, how the ECM is remodelled and how it is affected by ageing.
    MeSH term(s) Animals ; Proteomics ; Heart ; Extracellular Matrix/metabolism ; Extracellular Matrix Proteins/metabolism ; Arrhythmias, Cardiac/metabolism
    Chemical Substances Extracellular Matrix Proteins
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24054713
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Framing Heartaches

    Nathalie Ringström / Charlotte Edling / Giovanna Nalesso / Kamalan Jeevaratnam

    International Journal of Molecular Sciences, Vol 24, Iss 4713, p

    The Cardiac ECM and the Effects of Age

    2023  Volume 4713

    Abstract: The cardiac extracellular matrix (ECM) is involved in several pathological conditions, and age itself is also associated with certain changes in the heart: it gets larger and stiffer, and it develops an increased risk of abnormal intrinsic rhythm. This, ... ...

    Abstract The cardiac extracellular matrix (ECM) is involved in several pathological conditions, and age itself is also associated with certain changes in the heart: it gets larger and stiffer, and it develops an increased risk of abnormal intrinsic rhythm. This, therefore, makes conditions such as atrial arrythmia more common. Many of these changes are directly related to the ECM, yet the proteomic composition of the ECM and how it changes with age is not fully resolved. The limited research progress in this field is mainly due to the intrinsic challenges in unravelling tightly bound cardiac proteomic components and also the time-consuming and costly dependency on animal models. This review aims to give an overview of the composition of the cardiac ECM, how different components aid the function of the healthy heart, how the ECM is remodelled and how it is affected by ageing.
    Keywords ageing ; extracellular matrix ; cardiovascular medicine ; cardiac remodelling ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Impact of accessible-distributed model for research mentorship: A prospective survey study.

    Tse, Gary / Liu, Tong / Chan, Jeffrey Shi Kai / Baranchuk, Adrian / Jeevaratnam, Kamalan / Lee, Sharen

    The clinical teacher

    2023  Volume 21, Issue 1, Page(s) e13663

    MeSH term(s) Humans ; Mentors ; Prospective Studies ; Mentoring ; Internship and Residency ; Surveys and Questionnaires
    Language English
    Publishing date 2023-10-03
    Publishing country England
    Document type Letter
    ZDB-ID 2151518-9
    ISSN 1743-498X ; 1743-4971
    ISSN (online) 1743-498X
    ISSN 1743-4971
    DOI 10.1111/tct.13663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Feedback contributions to excitation-contraction coupling in native functioning striated muscle.

    Salvage, Samantha C / Dulhunty, Angela F / Jeevaratnam, Kamalan / Jackson, Antony P / Huang, Christopher L-H

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences

    2023  Volume 378, Issue 1879, Page(s) 20220162

    Abstract: Skeletal and cardiac muscle excitation-contraction coupling commences with ... ...

    Abstract Skeletal and cardiac muscle excitation-contraction coupling commences with Na
    MeSH term(s) Animals ; Mice ; Ryanodine Receptor Calcium Release Channel/chemistry ; Ryanodine Receptor Calcium Release Channel/genetics ; Dantrolene/pharmacology ; Feedback ; Muscle, Skeletal ; Action Potentials ; Calcium/metabolism
    Chemical Substances Ryanodine Receptor Calcium Release Channel ; Dantrolene (F64QU97QCR) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2023-05-01
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 208382-6
    ISSN 1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
    ISSN (online) 1471-2970
    ISSN 0080-4622 ; 0264-3839 ; 0962-8436
    DOI 10.1098/rstb.2022.0162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Ageing and the Autonomic Nervous System.

    Takla, Michael / Saadeh, Khalil / Tse, Gary / Huang, Christopher L-H / Jeevaratnam, Kamalan

    Sub-cellular biochemistry

    2023  Volume 103, Page(s) 201–252

    Abstract: The vertebrate nervous system is divided into central (CNS) and peripheral (PNS) components. In turn, the PNS is divided into the autonomic (ANS) and enteric (ENS) nervous systems. Ageing implicates time-related changes to anatomy and physiology in ... ...

    Abstract The vertebrate nervous system is divided into central (CNS) and peripheral (PNS) components. In turn, the PNS is divided into the autonomic (ANS) and enteric (ENS) nervous systems. Ageing implicates time-related changes to anatomy and physiology in reducing organismal fitness. In the case of the CNS, there exists substantial experimental evidence of the effects of age on individual neuronal and glial function. Although many such changes have yet to be experimentally observed in the PNS, there is considerable evidence of the role of ageing in the decline of ANS function over time. As such, this chapter will argue that the ANS constitutes a paradigm for the physiological consequences of ageing, as well as for their clinical implications.
    MeSH term(s) Autonomic Nervous System/physiology ; Neurons
    Language English
    Publishing date 2023-04-29
    Publishing country United States
    Document type Journal Article
    ISSN 0306-0225 ; 0096-8757
    ISSN 0306-0225 ; 0096-8757
    DOI 10.1007/978-3-031-26576-1_10
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