LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 776

Search options

  1. Article ; Online: Acyl-ghrelin therapy for heart failure: already a novel inotrope or even more?

    Jankowska, Ewa A / Ponikowski, Piotr

    European heart journal

    2023  Volume 44, Issue 22, Page(s) 2026–2028

    MeSH term(s) Humans ; Ghrelin/metabolism ; Calcium ; Myocytes, Cardiac/metabolism ; Heart Failure/physiopathology
    Chemical Substances acyl-ghrelin ; Ghrelin ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2023-06-09
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad220
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Iron Deficiency in Heart Failure: A Korea-Oriented Review.

    Jankowska, Ewa A / Ponikowski, Piotr

    International journal of heart failure

    2023  Volume 5, Issue 4, Page(s) 173–183

    Abstract: Iron deficiency (ID) occurs at high frequency across the spectrum of heart failure (HF), with HF severity and race being potentially important predictors for its development. ID, irrespective of anaemia status, leads to poor outcomes in patients with HF, ...

    Abstract Iron deficiency (ID) occurs at high frequency across the spectrum of heart failure (HF), with HF severity and race being potentially important predictors for its development. ID, irrespective of anaemia status, leads to poor outcomes in patients with HF, including exacerbated reduction in exercise capacity, poor quality of life (QoL) and increased risk of HF hospitalisation. As ID has a large public health and economic burden in Asia, and patients hospitalised with acute HF in the Asia Pacific vs. other regions commonly present with more severe clinical symptoms, there is a clear need to identify and treat ID promptly in Asian patients with HF. The biomarkers serum ferritin and transferrin saturation are used for ID diagnosis, and periodic screening is recommended in all patients with HF. The intravenous iron treatments, ferric carboxymaltose (FCM) and ferric derisomaltose, have demonstrated efficacy and tolerability in patients with acute or chronic HF and ID, with FCM shown to be cost-effective (and in some cases cost-saving). Meta-analyses support the likely benefits of intravenous FCM for improving QoL and reducing HF hospitalisation, without reducing mortality risk in patients with HF and ID. Accordingly, European Society of Cardiology guidelines recommend considering intravenous FCM for patients with symptomatic HF with left ventricular ejection fraction ≤50% who were recently hospitalised for HF and have ID. Although analyses of Asian patients with HF and ID are limited, the effects of intravenous iron would be expected to be similar to that in White populations; further clarifying studies may be of interest.
    Language English
    Publishing date 2023-10-25
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ISSN 2636-1558
    ISSN (online) 2636-1558
    DOI 10.36628/ijhf.2023.0032
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Intravenous iron supplementation: novel anti-remodelling therapy for patients with heart failure?

    Jankowska, Ewa A / Ponikowski, Piotr

    European heart journal

    2021  Volume 42, Issue 48, Page(s) 4915–4918

    MeSH term(s) Anemia, Iron-Deficiency/drug therapy ; Dietary Supplements ; Heart Failure/drug therapy ; Humans ; Iron
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2021-09-14
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehab624
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Dilemmas on diagnosis and treatment of iron deficiency in patients after an episode of acute heart failure.

    Jankowska, Ewa A / Ponikowski, Piotr

    European heart journal

    2021  Volume 43, Issue 4, Page(s) 347–348

    MeSH term(s) Anemia, Iron-Deficiency/diagnosis ; Anemia, Iron-Deficiency/therapy ; Heart Failure/diagnosis ; Heart Failure/therapy ; Humans ; Iron Deficiencies
    Language English
    Publishing date 2021-11-23
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehab839
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Impact of Synthesis Parameters upon the Electronic Structure in PVD-Deposited Cd

    Das, Arkaprava / Partyka-Jankowska, Ewa / Zając, Marcin / Hemberg, Axel / Bittencourt, Carla

    ACS omega

    2024  Volume 9, Issue 8, Page(s) 9835–9846

    Abstract: The impact of different synthesis parameters, such as thickness, postsynthesis annealing temperature, and oxygen gas flow rate, upon the electronic structure is discussed in detail in the present experimental investigation. X-ray photoelectron ... ...

    Abstract The impact of different synthesis parameters, such as thickness, postsynthesis annealing temperature, and oxygen gas flow rate, upon the electronic structure is discussed in detail in the present experimental investigation. X-ray photoelectron spectroscopy (XPS) and X-ray absorption near-edge structure (XANES) spectroscopy techniques are used to evaluate the surface electronic properties along with the presence and stability of the CdO
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.4c00892
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Hypophosphataemia risk associated with ferric carboxymaltose in heart failure: A pooled analysis of clinical trials.

    Rosano, Giuseppe Mc / Kalantar-Zadeh, Kamyar / Jankowska, Ewa A

    ESC heart failure

    2023  Volume 10, Issue 2, Page(s) 1294–1304

    Abstract: Aims: Iron deficiency is a common finding among patients with heart failure (HF) and is associated with adverse outcomes, including decreased quality of life, increased risk of hospitalization, and decreased survival. Intravenous ferric carboxymaltose ( ... ...

    Abstract Aims: Iron deficiency is a common finding among patients with heart failure (HF) and is associated with adverse outcomes, including decreased quality of life, increased risk of hospitalization, and decreased survival. Intravenous ferric carboxymaltose (FCM) has been shown to improve outcomes among patients with HF and concomitant iron deficiency, but FCM is associated with an increased risk of hypophosphataemia. We aimed to better characterize this risk among HF populations.
    Methods and results: This pooled analysis examined data from 41 studies of adults with iron deficiency across disease states and therapeutic areas. Among the 7931 patients treated with FCM available for analysis, 14% made up the HF subgroup. Additional subgroups included women's health (36%), non-dialysis-dependent chronic kidney disease (NDD-CKD; 27%), haemodialysis-dependent chronic kidney disease (HD-CKD; 1%), gastrointestinal (10%), neurology (3%), and other (10%). The incidence of post-baseline moderate or severe hypophosphataemia (i.e. serum phosphate [PO
    Conclusions: The risk of laboratory-assessed hypophosphataemia in HF patients treated with FCM was lower than that seen in patients in other therapeutic areas treated with FCM, and clinical events associated with hypophosphataemia are uncommon with FCM therapy in this population. Appropriate monitoring, particularly soon after administration in the unlikely event of repeated dosing in HF patients, will allow for further refinement of management strategies. [Correction added on 24 February 2023, after first online publication: In the preceding sentence, "…administration, will allow…" has been corrected to "…administration in the unlikely event of repeated dosing in HF patients, will allow…" in this version.].
    MeSH term(s) Adult ; Female ; Humans ; Heart Failure/complications ; Heart Failure/drug therapy ; Hypophosphatemia/complications ; Hypophosphatemia/epidemiology ; Hypophosphatemia/etiology ; Iron Deficiencies ; Quality of Life ; Renal Insufficiency, Chronic/complications
    Chemical Substances ferric carboxymaltose (6897GXD6OE)
    Language English
    Publishing date 2023-02-01
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't
    ZDB-ID 2814355-3
    ISSN 2055-5822 ; 2055-5822
    ISSN (online) 2055-5822
    ISSN 2055-5822
    DOI 10.1002/ehf2.14286
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Targeting Iron Deficiency in Heart Failure: Existing Evidence and Future Expectations.

    Ponikowski, Piotr / Jankowska, Ewa A

    Circulation. Heart failure

    2021  Volume 14, Issue 5, Page(s) e008299

    MeSH term(s) Anemia, Iron-Deficiency/diagnosis ; Anemia, Iron-Deficiency/drug therapy ; Ferritins ; Heart Failure/diagnosis ; Heart Failure/therapy ; Hemoglobins/metabolism ; Humans ; Motivation
    Chemical Substances Hemoglobins ; Ferritins (9007-73-2)
    Language English
    Publishing date 2021-05-18
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2429459-7
    ISSN 1941-3297 ; 1941-3289
    ISSN (online) 1941-3297
    ISSN 1941-3289
    DOI 10.1161/CIRCHEARTFAILURE.121.008299
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Synthesis and Characterization of Proton-Conducting Composites Prepared by Introducing Imidazole or 1,2,4-Triazole into AlPO-5 and SAPO-5 Molecular Sieves.

    Ostrowski, Adam / Jankowska, Aldona / Tabero, Agata / Janiszewska, Ewa / Kowalak, Stanisław

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 21

    Abstract: The present work concerns proton-conducting composites obtained by replacing the water molecules present in aluminophosphate and silicoaluminophosphate AFI-type molecular sieves (AlPO-5 and SAPO-5) with azole molecules (imidazole or 1,2,4-triazole). Both ...

    Abstract The present work concerns proton-conducting composites obtained by replacing the water molecules present in aluminophosphate and silicoaluminophosphate AFI-type molecular sieves (AlPO-5 and SAPO-5) with azole molecules (imidazole or 1,2,4-triazole). Both the introduction of azoles and the generation of Brønsted acid centers by isomorphous substitution in aluminophosphate materials were aimed at improving the proton conductivity of the materials and its stability. In the presented study, AlPO-5 and several SAPO-5 materials differing in silicon content were synthesized. The obtained porous matrices were studied using PXRD, low-temperature nitrogen sorption, TPD-NH
    Language English
    Publishing date 2023-10-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28217312
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Telemedicine in Heart Failure in the COVID-19 and Post-Pandemic Era: What Have We Learned?

    Sokolski, Mateusz / Kalużna-Oleksy, Marta / Tycińska, Agnieszka / Jankowska, Ewa A

    Biomedicines

    2023  Volume 11, Issue 8

    Abstract: Numerous studies showed that patients with heart failure (HF) and COVID-19 are at high risk of in-hospital complications and long-term mortality. Changes in the organisation of the medical system during the pandemic also worsened access to standard ... ...

    Abstract Numerous studies showed that patients with heart failure (HF) and COVID-19 are at high risk of in-hospital complications and long-term mortality. Changes in the organisation of the medical system during the pandemic also worsened access to standard procedures, increasing the general mortality in HF and forcing the systems to be reorganised with the implementation and development of telemedical technologies. The main challenges for HF patients during the pandemic could be solved with new technologies aimed to limit the risk of SARS-CoV-2 transmission, optimise and titrate the therapy, prevent the progression and worsening of HF, and monitor patients with acute HF events in the course of and after COVID-19. Dedicated platforms, phone calls or video conferencing and consultation, and remote non-invasive and invasive cardiac monitoring became potential tools used to meet the aforementioned challenges. These solutions showed to be effective in the model of care for patients with HF and undoubtedly will be developed after the experience of the pandemic. However, the multitude of possibilities requires central coordination and collaboration between institutes with data protection and cost reimbursement to create effective mechanisms in HF management. It is crucial that lessons be learned from the pandemic experience to improve the quality of care for HF patients.
    Language English
    Publishing date 2023-08-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11082222
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Effective cardioprotection with early initiation of sacubitrilvalsartan in a patient with breast cancer and cancer treatment-induced heart failure.

    Sławiński, Grzegorz / Jankowska, Hanna / Liżewska-Springer, Aleksandra / Lewicka, Ewa

    Kardiologia polska

    2022  Volume 80, Issue 7-8, Page(s) 869–870

    MeSH term(s) Breast Neoplasms/drug therapy ; Female ; Heart ; Heart Failure/drug therapy ; Humans
    Language English
    Publishing date 2022-06-15
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.a2022.0145
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top