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Book: The cell

Cooper, Geoffrey M. / Hausman, Robert E.

a molecular approach

2013

Author's details	Geoffrey M. Cooper ; Robert E. Hausman
Keywords	Cells ; Cell Biology ; Molecular Biology
Language	English
Size	XXV, 832 S. : Ill., graph. Darst.
Edition	6. ed.
Publisher	Sinauer Assoc
Publishing place	Sunderland, Mass
Publishing country	United States
Document type	Book
Note	Includes bibliographical references and index
Accompanying material	Hinweis auf zusätzliches Internetmaterial im Buch
HBZ-ID	HT017546878
ISBN	978-0-87893-964-0 ; 0-87893-964-4
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2013 A 490	available for loan (reading room)	Lesesaal EG

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Article ; Online: A rapid recovery protocol for head and neck oncology patients undergoing resection, free flap reconstruction, and tracheostomy: a feasibility study.

Niziol, R / Cooper, A / Jacovou, E / Christodoulides, G / Alibhai, M / Fry, A

International journal of oral and maxillofacial surgery

2024

Abstract: Enhanced recovery after surgery (ERAS) for head and neck oncology patients was first introduced in 2017 and was found to improve patient outcomes, in line with results from other surgical specialties. This article presents a rapid recovery protocol (RRP) ...

Abstract	Enhanced recovery after surgery (ERAS) for head and neck oncology patients was first introduced in 2017 and was found to improve patient outcomes, in line with results from other surgical specialties. This article presents a rapid recovery protocol (RRP) to further enhance perioperative care in conjunction with the ERAS protocol, for patients undergoing ablative surgery together with free flap reconstruction and tracheostomy. A prospective multidisciplinary approach was adopted to identify a specific cohort of patients who would benefit from the RRP. Of 26 patients who fulfilled the eligibility criteria, 16 completed the RRP. On average, these patients spent 5 days less with a tracheostomy and were discharged 7 days sooner when compared to a matched control group of nine patients on the standard postoperative care pathway. This resulted in an approximate monetary saving of £ 9955 per patient for the hospital trust. These results demonstrate that the feasibility study should be rolled out further, as the RRP not only decreased the length of stay but also provided substantial monetary savings without compromising patient outcomes.
Language	English
Publishing date	2024-01-03
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	353721-3
ISSN	1399-0020 ; 0901-5027
ISSN (online)	1399-0020
ISSN	0901-5027
DOI	10.1016/j.ijom.2023.11.012
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Zs.A 931: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 401: Show issues

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Article ; Online: Protein signaling and morphological development of the tail fluke in the embryonic beluga whale (Delphinapterus leucas).

Gavazzi, L M / Nair, M / Suydam, R / Usip, S / Thewissen, J G M / Cooper, L N

Developmental dynamics : an official publication of the American Association of Anatomists

2024

Abstract: ... signals known to drive appendage outgrowth in other vertebrates (e.g., Sonic Hedgehog [SHH], GREMLIN [GREM ...

Abstract	Background: During the land-to-sea transition of cetaceans (whales, dolphins, and porpoises), the hindlimbs were lost and replaced by an elaborate tail fluke that evolved 32 Ma. All modern cetaceans utilize flukes for lift-based propulsion, and nothing is known of this organ's molecular origins during embryonic development. This study utilizes immunohistochemistry to identify the spatiotemporal location of protein signals known to drive appendage outgrowth in other vertebrates (e.g., Sonic Hedgehog [SHH], GREMLIN [GREM], wingless-type family member 7a [WNT], and fibroblast growth factors [FGFs]) and to test the hypothesis that signals associated with outgrowth and patterning of the tail fluke are similar to a tetrapod limb. Specifically, this study utilizes an embryo of a beluga whale (Delphinapterus leucas) as a case study. Results: Results showed epidermal signals of WNT and FGFs, and mesenchymal/epidermal signals of SHH and GREM. These patterns are most consistent with vertebrate limb development. Overall, these data are most consistent with the hypothesis that outgrowth of tail flukes in cetaceans employs a signaling pattern that suggests genes essential for limb outgrowth and patterning shape this evolutionarily novel appendage. Conclusions: While these data add insights into the molecular signals potentially driving the evolution and development of tail flukes in cetaceans, further exploration of the molecular drivers of fluke development is required.
Language	English
Publishing date	2024-03-17
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1102541-4
ISSN	1097-0177 ; 1058-8388
ISSN (online)	1097-0177
ISSN	1058-8388
DOI	10.1002/dvdy.704
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Zs.MG 64: Show issues

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Article ; Online: Evaluation of Electric and Air-Powered Shopping Scooters in Grocery Stores.

Daveler, Brandon J / Gebrosky, Benjamin / Eckstein, Ian J / Grindle, Garrett G / Cooper, Rosemarie / Cooper, Rory A

American journal of physical medicine & rehabilitation

2024

Abstract: Objective: The purpose of this study was to further previous research and gather additional information regarding the usage of motorized shopping scooters as well as feedback for improvements to an air-powered scooter.: Methods: Online surveys were ... ...

Abstract	Objective: The purpose of this study was to further previous research and gather additional information regarding the usage of motorized shopping scooters as well as feedback for improvements to an air-powered scooter. Methods: Online surveys were used to assess individuals' shopping characteristics and experience using the motorized scooters and to gather feedback from store employees regarding their experience. K-Means clustering analysis was used to determine user demographics who chose to use the air-powered scooter versus the electric powered scooter while shopping. Results: A total of 127 individuals provided informed consent, 65 individuals from Site 1 and 62 individuals from Site 2. 120 participants met the inclusion criteria and completed the survey. K-Means clustering found that age, type of personal mobility device, shopping bill total, and frequency using a motorized shopping scooter to be significant factors in whether individuals chose to use an air-powered scooter or electric-powered scooter. Conclusion: Motorized shopping scooters are in high demand and used by a wide variety of individuals, yet electric-powered scooters are commonly unavailable due to having dead batteries or all the devices being in use. Air-powered scooters may serve as a practical replacement for the current electric-powered scooters found in grocery and retail stores.
Language	English
Publishing date	2024-02-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	219390-5
ISSN	1537-7385 ; 0002-9491 ; 0894-9115
ISSN (online)	1537-7385
ISSN	0002-9491 ; 0894-9115
DOI	10.1097/PHM.0000000000002457
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Article ; Online: Are associations between physical activity and bone mineral density in adults sex- and age-dependent? An analysis of the UK Biobank study.

Montgomery, Gallin / Yusuf, Mohamed / Cooper, Rachel / Ireland, Alex

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

2024 Volume 39, Issue 4, Page(s) 399–407

Abstract: Although physical activity (PA) is recognized as a key bone mass determinant across life, athlete studies suggest that it may be less effective in women and older individuals. This has not been explored within the general population. We aimed to address ... ...

Abstract	Although physical activity (PA) is recognized as a key bone mass determinant across life, athlete studies suggest that it may be less effective in women and older individuals. This has not been explored within the general population. We aimed to address this knowledge gap using data from the UK Biobank Study, a large population-based study of middle-aged and older adults. Free-living PA data collected at 100 Hz for 7 d using wrist-worn accelerometers were classified as sedentary behavior (0-29 milligravities [mg]), light (30-124 mg), or moderate-to-vigorous PA (125 + mg). LS and FN-BMD were assessed using DXA. The associations between PA and BMD were assessed using linear regression models, with formal assessments of sex and age interactions undertaken and adjustments made for accelerometer wear time, height, body mass index, education, ethnicity, disability, and (in women only) menopausal status. In total, 15 133 UK Biobank participants (52% women) had complete PA, bone, and covariate data. In this sample, greater overall and moderate-to-vigorous PA was associated with higher LS BMD. In women, these associations were typically weaker in older individuals, for example, regression coefficients in women aged 70 yr or older were ~50% lower than at 45-54 yr (age-by-PA interactions P < .01 in all models). Similar associations were observed in basic but not full models for FN BMD. Greater sedentary time was associated with lower LS BMD in men only, and greater light PA and sedentary time were associated with higher and lower FN BMD, respectively, in both sexes. These results suggest that associations between PA and bone health at clinically-relevant sites are weaker in older than younger women. That positive associations are evident between overall and moderate-vigorous PA and FN BMD even in women ≥70 yr suggests that PA for bone health should still be promoted in older women.
MeSH term(s)	Humans ; Female ; Male ; Bone Density ; Exercise/physiology ; United Kingdom ; Middle Aged ; Aged ; Biological Specimen Banks ; Age Factors ; Sex Factors ; Sex Characteristics ; UK Biobank
Language	English
Publishing date	2024-03-14
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632783-7
ISSN	1523-4681 ; 0884-0431
ISSN (online)	1523-4681
ISSN	0884-0431
DOI	10.1093/jbmr/zjae017
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bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Visualizing Early Infection Sites of Rice Blast Disease (Magnaporthe oryzae) on Barley (Hordeum vulgare) Using a Basic Microscope and a Smartphone.

Cooper, Jessica G / Donofrio, Nicole M / Caplan, Jeffrey L / Chaya, Timothy R

Journal of visualized experiments : JoVE

2023 , Issue 193

Abstract: Understanding how plants and pathogens interact, and whether that interaction culminates in defense or disease, is required to develop stronger and more sustainable strategies for plant health. Advances in methods that more effectively image plant- ... ...

Abstract	Understanding how plants and pathogens interact, and whether that interaction culminates in defense or disease, is required to develop stronger and more sustainable strategies for plant health. Advances in methods that more effectively image plant-pathogen samples during infection and colonization have yielded tools such as the rice leaf sheath assay, which has been useful in monitoring infection and early colonization events between rice and the fungal pathogen, Magnaporthe oryzae. This hemi-biotrophic pathogen causes severe disease loss in rice and related monocots, including millet, rye, barley, and more recently, wheat. The leaf sheath assay, when performed correctly, yields an optically clear plant section, several layers thick, which allows researchers to perform live-cell imaging during pathogen attack or generate fixed samples stained for specific features. Detailed cellular investigations into the barley-M. oryzae interaction have lagged behind those of the rice host, in spite of the growing importance of this grain as a food source for animals and humans and as fermented beverages. Reported here is the development of a barley leaf sheath assay for intricate studies of M. oryzae interactions during the first 48 h post-inoculation. The leaf sheath assay, regardless of which species is being studied, is delicate; provided is a protocol that covers everything, from barley growth conditions and obtaining a leaf sheath, to inoculation, incubation, and imaging of the pathogen on plant leaves. This protocol can be optimized for high-throughput screening using something as simple as a smartphone for imaging purposes.
MeSH term(s)	Humans ; Hordeum ; Magnaporthe ; Smartphone ; Ascomycota ; Plant Diseases/microbiology ; Oryza
Language	English
Publishing date	2023-03-17
Publishing country	United States
Document type	Journal Article ; Video-Audio Media ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2259946-0
ISSN	1940-087X ; 1940-087X
ISSN (online)	1940-087X
ISSN	1940-087X
DOI	10.3791/64794
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: The cell

Cooper, Geoffrey M. / Hausman, Robert E.

a molecular approach

2009

Author's details	Geoffrey M. Cooper ; Robert E. Hausman
Keywords	Cells ; Cytology ; Molecular Biology ; Cytologie ; Zelle ; Molekularbiologie
Subject	Molekulare Biologie ; Zellbiologie ; Zellenlehre ; Zellforschung ; Zellkunde ; Zelluologie ; Zytologie ; Zelle
Language	English
Size	XIX, 820 S. : zahlr. Ill., graph. Darst.
Edition	5. ed.
Publisher	ASM Press u.a.
Publishing place	Washington, DC
Publishing country	United States
Document type	Book
Accompanying material	Freier Zugang zu begleitender Webseite im Buch vorhanden
HBZ-ID	HT015846647
ISBN	978-0-87893-300-6 ; 0-87893-300-X
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2009 A 3156	order for loan	Magazin

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Article ; Online: Fipronil Affects Craniofacial and Heart Development in Zebrafish Embryos (

Cooper, Kasey L / Krut, Zoe G / Franz, Bennet D / Walker, Benjamin S / Kramer, Alexander G / Morgan, Jonathan R / Lassiter, Christopher S

Zebrafish

2024 Volume 21, Issue 2, Page(s) 181–190

Abstract: Fipronil is a broad-spectrum insecticide that has off-target effects in developing vertebrate embryos. In this study, we investigate treatment of zebrafish embryos with fipronil over the course of 5 days and examine the effects on body length, the ... ...

Abstract	Fipronil is a broad-spectrum insecticide that has off-target effects in developing vertebrate embryos. In this study, we investigate treatment of zebrafish embryos with fipronil over the course of 5 days and examine the effects on body length, the cardiovascular system, and craniofacial morphology. We found the insecticide caused shorter body length and a decrease in eye size. By examining specific heart chamber morphology, as well as jaw angle and length, we quantified defects including enlargement of the heart and increases in jaw length and width. Further studies are needed to assess the mechanisms of fipronil's effect on vertebrate development for both environmental and human health concerns.
MeSH term(s)	Animals ; Humans ; Zebrafish ; Insecticides/toxicity ; Embryo, Nonmammalian ; Pyrazoles/toxicity ; Water Pollutants, Chemical
Chemical Substances	Insecticides ; fipronil (QGH063955F) ; Pyrazoles ; Water Pollutants, Chemical
Language	English
Publishing date	2024-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2156020-1
ISSN	1557-8542 ; 1545-8547
ISSN (online)	1557-8542
ISSN	1545-8547
DOI	10.1089/zeb.2023.0055
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The role of landscape and parent material on regolith under timber plantations at Highflats, KwaZulu-Natal, South Africa

Cooper, G.D. / Morris, A. / Botha, G. / Titshall, L. / Burgdorf, R.J. / Rozanov, A.

Geoderma Regional. 2023 Mar., v. 32 p.e00608-

2023

Abstract: Regolith is an important component of the Earth's critical zone. Little investigative work has been done in southern Africa on regolith characteristics as a component of the critical zone, and in particular the importance to forestry plantation ... ...

Abstract	Regolith is an important component of the Earth's critical zone. Little investigative work has been done in southern Africa on regolith characteristics as a component of the critical zone, and in particular the importance to forestry plantation productivity in the eastern hinterland of South Africa. Regolith cores were extracted from five positions across two slopes underlain by sandstone and tillite to characterize these regolith profiles and ascertain the effect of slope position and parent material on regolith development. Regolith profiles were characterized and analysed on hill crest and lower midslope positions at both sites. The profile descriptions noted the degree of weathering, rooting activity, and mineral composition. The deepest in situ weathering of regolith was found on the hill crest positions; sandstone crest (24.0 m) and tillite crest (8.2 m) respectively. The accumulation of colluviated sediment on lower slopes also resulted in a thicker regolith at the tillite site, despite the less intensely weathered bedrock. These findings were consistent with earlier geophysical and pedohydrological studies of the area and the regolith profiles are consistent with those described for a range of other sedimentary lithologies in similar regions in sub-tropical and tropical landscapes The results show that tree roots utilize the saprolite and saprock below soil horizons and the nature of these layers indicate the full regolith profile should be considered in the water and nutrient supply available to forest plantations. Current concepts of ‘effective rooting depth’, as widely used by South African forestry, are inadequate for understanding ecosystem processes in forest plantations.
Keywords	bedrock ; ecosystems ; forestry ; forests ; geophysics ; hinterland ; landscapes ; lithology ; mineral content ; regolith ; sandstone ; saprolite ; sediments ; soil ; trees ; South Africa ; Slope ; Tillite ; Dolerite ; Cambisol ; Leptosol
Language	English
Dates of publication	2023-03
Publishing place	Elsevier B.V.
Document type	Article ; Online
ISSN	2352-0094
DOI	10.1016/j.geodrs.2023.e00608
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Step-by-Step Approach to Build Multiple Reaction Monitoring (MRM) Profiling Instrument Acquisition Methods for Class-based Lipid Exploratory Analysis by Mass Spectrometry.

Reis, Leriana G / Casey, Theresa M / Sobreira, Tiago J P / Cooper, Bruce R / Ferreira, Christina R

Journal of biomolecular techniques : JBT

2023 Volume 34, Issue 2

Abstract: Multiple reaction monitoring (MRM) profiling is a strategy for the exploratory analysis of small molecules and lipids by direct sample injection, ie, without the use of chromatographic separation. It is based on instrument methods that comprise a list of ...

Abstract	Multiple reaction monitoring (MRM) profiling is a strategy for the exploratory analysis of small molecules and lipids by direct sample injection, ie, without the use of chromatographic separation. It is based on instrument methods that comprise a list of ion transitions (MRMs), in which the precursor ion is the expected ionized
MeSH term(s)	Mass Spectrometry ; Carbon ; Databases, Factual ; Fatty Acids ; Isomerism
Chemical Substances	Carbon (7440-44-0) ; Fatty Acids
Language	English
Publishing date	2023-06-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2116011-9
ISSN	1943-4731 ; 1943-4731
ISSN (online)	1943-4731
ISSN	1943-4731
DOI	10.7171/3fc1f5fe.1972c438
Database	MEDical Literature Analysis and Retrieval System OnLINE

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