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  1. Article: Erratum corrige: "Increased expression of interferon-λ in minor salivary glands of patients with primary Sjögren's syndrome and its synergic effect with interferon-α on salivary gland epithelial cells". Y.-J. Ha et al.

    Ha, You-Jung / Choi, Yong Seok / Kang, Eun Ha / Chung, Jin-Haeng / Cha, Seunghee / Song, Yeong Wook / Lee, Yun Jong

    Clinical and experimental rheumatology

    2018  Volume 36, Issue 5, Page(s) 936

    Language English
    Publishing date 2018-09-26
    Publishing country Italy
    Document type Journal Article ; Published Erratum
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2002: Show issues Location:
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  2. Article: [Validation of a C57/BL6J mouse model of focal cerebral ischemia established by electrocoagulation of the middle cerebral artery].

    Kang, Y / Tang, D / Zhang, J / Xia, Q

    Nan fang yi ke da xue xue bao = Journal of Southern Medical University

    2024  Volume 44, Issue 1, Page(s) 100–107

    Abstract: Objective: To modify the method for establishing mouse models of middle cerebral artery occlusion (MCAO)-induced focal cerebral ischemia using electrocoagulation.: Methods: Forty-six C57/BL6J male mice were divided into MCAO model group (: Results!# ...

    Abstract Objective: To modify the method for establishing mouse models of middle cerebral artery occlusion (MCAO)-induced focal cerebral ischemia using electrocoagulation.
    Methods: Forty-six C57/BL6J male mice were divided into MCAO model group (
    Results: The mice in the model group showed significantly reduced cerebral blood flow in the MCA on the ischemic side and obvious neurological deficits with increased forelimb use asymmetry on days 1, 7 and 14 after modeling (
    Conclusion: We successfully prepared mouse models of MCAO using a modified method by changing the electrocoagulation location from the distal location of the junction between the MCA and the inferior cerebral vein to a 2 mm segment medial to the junction between the MCA and the olfactory bundle.
    MeSH term(s) Male ; Mice ; Animals ; Middle Cerebral Artery/surgery ; Brain-Derived Neurotrophic Factor ; Brain Ischemia ; Infarction, Middle Cerebral Artery ; Staining and Labeling ; Disease Models, Animal
    Chemical Substances Brain-Derived Neurotrophic Factor
    Language Chinese
    Publishing date 2024-01-31
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2250951-3
    ISSN 1673-4254
    ISSN 1673-4254
    DOI 10.12122/j.issn.1673-4254.2024.01.12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6344: Show issues Location:
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  3. Article: [Value of transnasal high-flow oxygen therapy and noninvasive ventilation in the management of acute respiratory distress syndrome].

    Yang, S / Yang, J / Kang, Y

    Zhonghua yi xue za zhi

    2024  Volume 104, Issue 15, Page(s) 1230–1235

    Abstract: Acute respiratory distress syndrome (ARDS) is one of the most common syndromes in the intensive care unit, with a high mortality and morbidity. Refractory hypoxia is the typical feature of ARDS, and improving hypoxia is the key to the treatment of ARDS. ... ...

    Abstract Acute respiratory distress syndrome (ARDS) is one of the most common syndromes in the intensive care unit, with a high mortality and morbidity. Refractory hypoxia is the typical feature of ARDS, and improving hypoxia is the key to the treatment of ARDS. Due to the rapid progression of ARDS, invasive ventilation is usually used to improve hypoxia. But in recent years, with the extending of the understanding of ARDS and the development of non-invasive oxygen therapy, high flow nasal oxygen (HFNO) and non-invasive ventilation (NIV) are gradually used in ARDS. Therefore, we reviewed the role of HFNO and NIV in ARDS in this paper.
    MeSH term(s) Humans ; Noninvasive Ventilation ; Respiration, Artificial ; Oxygen ; Respiratory Distress Syndrome/therapy ; Hypoxia/therapy ; Respiratory Insufficiency/therapy
    Chemical Substances Oxygen (S88TT14065)
    Language Chinese
    Publishing date 2024-04-18
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20231023-00865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Associations of meeting 24-h movement guidelines and metabolic syndrome in Korean adults during the COVID-19 pandemic.

    Shin, S W / Choi, Y / Kang, Y H / Kim, J

    Public health

    2024  Volume 227, Page(s) 187–193

    Abstract: Objectives: This study aimed to investigate the association between adherence to 24-h movement guidelines and metabolic syndrome (MetS) before and during the COVID-19 pandemic.: Study design: Repeated cross-sectional design.: Methods: We selected ... ...

    Abstract Objectives: This study aimed to investigate the association between adherence to 24-h movement guidelines and metabolic syndrome (MetS) before and during the COVID-19 pandemic.
    Study design: Repeated cross-sectional design.
    Methods: We selected 10,882 adults (2019: n = 5710; 2020: n = 5172) aged ≥20 years from the Korea National Health and Nutrition Examination Survey. Domain-specific physical activity and sedentary behavior were assessed using a global physical activity questionnaire. We also measured the typical sleep duration (h/day) on weekdays and weekends. MetS was defined as the presence of more than three risk factors.
    Results: During the COVID-19 pandemic, transportation-related physical activity decreased, while the prevalence of abdominal obesity (+3.3 %) and low HDL-C levels (+3.1 %) increased significantly. An elevated risk of MetS was observed in the lower aerobic (odds ratio [OR], 1.28; 95% confidence interval [CI], 1.04-1.58; P = 0.019) and muscular exercise (OR, 1.31; 95% CI, 1.04-1.66; P = 0.023) groups and in the high sedentary behavior (OR, 1.23; 95% CI, 1.00-1.51; P = 0.049) during the pandemic. Sensitivity analysis stratified by sex showed similar patterns with more pronounced changes in MetS components in males. The models also showed significant associations between aerobic physical activity, strength exercises, and sedentary behavior with MetS in males and females.
    Conclusions: Although sedentary behavior and sleep time remained unchanged, a significant decrease in transportation-related physical activity was observed during the pandemic. Moreover, our findings revealed that aerobic physical activity, strength exercise, and sedentary time during the pandemic were associated with an increased MetS risk. These results highlight the importance of promoting physical activity, particularly during periods of social restriction, to mitigate the pandemic's negative effects on metabolic health.
    MeSH term(s) Adult ; Male ; Female ; Humans ; Metabolic Syndrome/epidemiology ; Pandemics ; Nutrition Surveys ; Cross-Sectional Studies ; COVID-19/epidemiology ; COVID-19/complications ; Republic of Korea/epidemiology
    Language English
    Publishing date 2024-01-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 427333-3
    ISSN 1476-5616 ; 0033-3506
    ISSN (online) 1476-5616
    ISSN 0033-3506
    DOI 10.1016/j.puhe.2023.12.020
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  5. Article: [Using PGT to give birth to hereditary conductive deafness SYNS1 family a healthy offspring: a case report].

    Fu, Y / Huang, S S / Wang, Q Q / Han, M Y / Wang, G J / Kang, D Y / Dai, P / Yuan, Y Y

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2024  Volume 59, Issue 3, Page(s) 243–248

    MeSH term(s) Humans ; Genetic Testing ; Hearing Loss, Conductive ; Deafness/genetics
    Language Chinese
    Publishing date 2024-04-01
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20230925-00116
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    Zs.A 3733: Show issues Location:
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  6. Article: [Progress of artificial intelligence in gynecological oncology].

    Chen, M X / Gao, Y / Kang, Y / Xu, C J

    Zhonghua fu chan ke za zhi

    2023  Volume 57, Issue 1, Page(s) 72–78

    MeSH term(s) Female ; Humans ; Artificial Intelligence ; Genital Neoplasms, Female/therapy
    Language Chinese
    Publishing date 2023-05-16
    Publishing country China
    Document type Journal Article
    ZDB-ID 604570-4
    ISSN 0529-567X
    ISSN 0529-567X
    DOI 10.3760/cma.j.cn112141-20210924-00549
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    Zs.MO 324: Show issues

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  7. Article ; Online: IV low dose ketamine infusions for treatment resistant depression: Results from a five-year study at a free public clinic in an academic hospital.

    Gutierrez, Gilmar / Kang, Melody J Y / Vazquez, Gustavo

    Psychiatry research

    2024  Volume 335, Page(s) 115865

    Abstract: Individuals with major depressive disorder and treatment resistant depression (MDD-TRD) have limited and sometimes poorly tolerated therapeutic options. Low dose ketamine has presented promising and potent antidepressant effects in this population. To ... ...

    Abstract Individuals with major depressive disorder and treatment resistant depression (MDD-TRD) have limited and sometimes poorly tolerated therapeutic options. Low dose ketamine has presented promising and potent antidepressant effects in this population. To support the existent literature, we conducted a longitudinal study examining five years of real-world clinical data on the use of IV low-dose ketamine alongside standard care for MDD-TRD outpatients. For this study we collected demographic information, clinical scale scores, side effects and dropout data. The data was analyzed using descriptive statistics, effect size using Cohen's D analysis, and multivariate ANOVA (MANOVA) to determine the impact of sociodemographic variables. 71 outpatients (50.28 years old, SD: 14.26; female 74.65%) were included in the analysis. The results showed a significant reduction in depressive symptoms and suicide ideation (SI) by treatment endpoint. 54.93% of patients responded to the treatment, 78.26% experienced transient and mild side effects, and 11.27% of dropped out of the treatment. Multivariate analysis showed that the demographic variables did not impact treatment effect or tolerability. The results of this study suggest that IV low dose ketamine treatment is effective, fast-acting, and well tolerated for the management of depressive symptoms and SI in patients with MDD-TRD in naturalistic clinical practice.
    MeSH term(s) Humans ; Female ; Middle Aged ; Ketamine ; Depressive Disorder, Treatment-Resistant/drug therapy ; Depressive Disorder, Treatment-Resistant/diagnosis ; Depressive Disorder, Major/diagnosis ; Longitudinal Studies ; Infusions, Intravenous ; Suicidal Ideation ; Depression/drug therapy
    Chemical Substances Ketamine (690G0D6V8H)
    Language English
    Publishing date 2024-03-19
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 445361-x
    ISSN 1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
    ISSN (online) 1872-7123 ; 1872-7506
    ISSN 0925-4927 ; 0165-1781
    DOI 10.1016/j.psychres.2024.115865
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    Zs.A 1541: Show issues Location:
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  8. Article ; Online: Nodular mass in the nasal columella of a 15-year-old girl.

    Jeon, Y / Shin, S-J / Jin, J C / Kang, J W

    European annals of otorhinolaryngology, head and neck diseases

    2023  Volume 140, Issue 3, Page(s) 139–140

    MeSH term(s) Female ; Humans ; Adolescent ; Nasal Septum/surgery ; Rhinoplasty
    Language English
    Publishing date 2023-01-11
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 2558008-5
    ISSN 1879-730X ; 1879-7296
    ISSN (online) 1879-730X
    ISSN 1879-7296
    DOI 10.1016/j.anorl.2022.12.009
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  9. Article ; Online: Histone H3K4ac, as a marker of active transcription start sites and enhancers, plays roles in histone eviction and RNA transcription.

    Kang, Jin / Kang, Yujin / Kim, AeRi

    Biochimica et biophysica acta. Gene regulatory mechanisms

    2024  Volume 1867, Issue 2, Page(s) 195021

    Abstract: The lysine 4 of histone H3 (H3K4) can be methylated or acetylated into four states: H3K4me1, H3K4me2, H3K4me3, or H3K4ac. Unlike H3K4 methylation, the genome-wide distribution and functional roles of H3K4ac remain unclear. To understand the relationship ... ...

    Abstract The lysine 4 of histone H3 (H3K4) can be methylated or acetylated into four states: H3K4me1, H3K4me2, H3K4me3, or H3K4ac. Unlike H3K4 methylation, the genome-wide distribution and functional roles of H3K4ac remain unclear. To understand the relationship of acetylation with methylation at H3K4 and to explore the roles of H3K4ac in the context of chromatin, we analyzed H3K4ac across the human genome and compared it with H3K4 methylation in K562 cells. H3K4ac was positively correlated with H3K4me1/2/3 in reciprocal analysis. A decrease in H3K4ac through the mutation of the histone acetyltransferase p300 reduced H3K4me1 and H3K4me3 at the H3K4ac peaks. H3K4ac was also impaired by H3K4me depletion in the histone methyltransferase MLL3/4-mutated cells. H3K4ac peaks were enriched at enhancers in addition to the transcription start sites (TSSs) of genes. H3K4ac of TSSs and enhancers was positively correlated with mRNA and eRNA transcription. A decrease in H3K4ac reduced H3K4me3 and H3K4me1 in TSSs and enhancers, respectively, and inhibited the eviction of histone H3 from them. The mRNA transcription of highly transcribed genes was affected by the reduced H3K4ac. Interestingly, H3K4ac played a redundant role with regard to H3K27ac in eRNA transcription. These results indicate that H3K4ac serves as a marker of both active TSSs and enhancers and plays a role in histone eviction and RNA transcription by leading to H3K4me1/3.
    Language English
    Publishing date 2024-02-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2918786-2
    ISSN 1876-4320 ; 1874-9399
    ISSN (online) 1876-4320
    ISSN 1874-9399
    DOI 10.1016/j.bbagrm.2024.195021
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  10. Article: [Early to mid-term clinical outcomes of aortic valve repair in patients with bicuspid aortic insufficiency].

    Sun, J / Zhang, S / Kang, W Y / Chang, Y / Zhao, D / Guo, H W / Qian, X Y / Zheng, Z

    Zhonghua wai ke za zhi [Chinese journal of surgery

    2024  Volume 62, Issue 5, Page(s) 393–399

    Abstract: Objective: ...

    Abstract Objective:
    Language Chinese
    Publishing date 2024-03-27
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 604573-x
    ISSN 0529-5815
    ISSN 0529-5815
    DOI 10.3760/cma.j.cn112139-20240111-00024
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